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  1. 27501

    Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion. by Harriet V Mears, George R Young, Theo Sanderson, Ruth Harvey, Jamie Barrett-Rodger, Rebecca Penn, Vanessa Cowton, Wilhelm Furnon, Giuditta De Lorenzo, Margaret Crawford, Daniel M Snell, Ashley S Fowler, Anob M Chakrabarti, Saira Hussain, Ciarán Gilbride, Edward Emmott, Katja Finsterbusch, Jakub Luptak, Thomas P Peacock, Jérôme Nicod, Arvind H Patel, Massimo Palmarini, Emma Wall, Bryan Williams, Sonia Gandhi, Charles Swanton, David L V Bauer

    Published 2025-01-01
    “…We show well-supported examples upstream of the Spike gene-within the nsp16 coding region of ORF1b-which is expressed during human infection, and upstream of the canonical Envelope gene TRS, both of which have evolved convergently in multiple lineages. …”
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  2. 27502

    Case report: Patients with positive HER-2 amplification locally advanced gastroesophageal junction cancer achieved pathologic complete response with the addition of pembrolizumab t... by Huanhuan Li, Chao Ren, Donghai Cui, Tao Wu, Zhiyong Nie

    Published 2025-02-01
    “…BackgroundHuman epidermal growth factor receptor 2(HER-2) is the most prominent therapeutic target for gastric (G)/gastroesophageal junction (GEJ) cancer. …”
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  3. 27503

    Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions by Ghaleb Elyamany, Eman Al Mussaed, Ali Matar Alzahrani

    Published 2015-01-01
    “…Plasmablastic lymphoma (PBL) is an aggressive subtype of non-Hodgkin’s lymphoma (NHL), which frequently arises in the oral cavity of human immunodeficiency virus (HIV) infected patients. …”
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  4. 27504

    Phonetic and Grammatical Characteristics of Mojtabā Minovi’s Pānzdah Goftār by Negar Khan Mohammadi, Naser Rahimi

    Published 2024-10-01
    “…For example, he used feminine Arabic adjectives for broken/internal plural (jam'-e mokassar) or singular Arabic nouns, compound prepositions in their complete form, such as az baraye (for), dar tahte (under), and dar moghe-ye (while), singular verb for a non-human plural subject, descriptive (participial) form frequently, and other such characteristics.…”
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  5. 27505

    BIOSYNTHESIS OF NANOPARTICLES FROM PLANT EXTRACTS AND THEIR APPLICATIONS IN MEDICAL TREATMENTS AND DRUG DELIVERY: A REVIEW by N. A. Jdayea, E. E. Al-Abodi

    Published 2024-12-01
    “…Green chemistry methods are suitable for producing and processing hazardous chemicals that threaten human health and the environment. This technology requires extensive experience in dealing with the raw materials, especially in the elements and metals used to transform them into nanomaterials and the resulting side effects and chemical reactions. nanotechnology has achieved a systemic breakthrough and metal nanoparticles (green nanoparticles) have received much attention due to their physiological, technological and chemical differences. …”
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  6. 27506

    Isolation, Identification, and Antimicrobial Study of Yersinia spp. Isolated from Traditional and Industrial Olivier Salad Specimens in Tehran by Farnaz Eskandarzadeh, Mohammad Reza Mohammadi, Abbas Rahimi Foroushani, Mohammad Mehdi Soltan Dallal

    Published 2025-02-01
    “…The biotype of Yersinia enterocolitica was investigated, and three strains of biotype 1A and one strain of biotype 1B were identified. The human pathogenic serotype was not found in the serotype analysis. …”
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  7. 27507

    Which curriculum components do medical students find most helpful for evaluating AI outputs? by William J. Waldock, George Lam, Ana Baptista, Risheka Walls, Amir H. Sam

    Published 2025-02-01
    “…Abstract Introduction The risk and opportunity of Large Language Models (LLMs) in medical education both rest in their imitation of human communication. Future doctors working with generative artificial intelligence (AI) need to judge the value of any outputs from LLMs to safely direct the management of patients. …”
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  8. 27508

    THE EFFECTS OF THE PRESENCE OF UiTM NEGERI SEMBILAN BRANCH CAMPUSES ON BUSINESSES IN KUALA PILAH, SEREMBAN AND REMBAU by A. N. Jannah, A. Shanthi

    Published 2024-10-01
    “…The impact of the establishment of UiTM Negeri Sembilan Branch can be seen not only through the growth it has brought to the human resources, academic and physical sectors, but can also be seen via the impact it has brought to the economic, political, social as well as the environment sectors on the communities of Kuala Pilah, Seremban, and Rembau. …”
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  9. 27509

    The Clinical Sociology Honours Programme at the University of KwaZulu-Natal (UKZN) in South Africa by Mariam Seedat-Khan, Jayanathan Govender

    Published 2024-12-01
    “…The programme focuses on understanding human behaviour in a social context, diagnosing social problems, and developing strategies for social change. …”
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  10. 27510

    The role of delays in innate and adaptive immunity to intracellular bacterial infection by Simeone Marino, Edoardo Beretta, Denise E. Kirschner

    Published 2007-01-01
    “…The immune response in humans is complex and multi-fold. Initially an innate response attempts to clear any invasion by microbes. …”
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  11. 27511

    DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells by Siti Razila Abdul Razak, Yukihiro Baba, Hiromitsu Nakauchi, Makoto Otsu, Sumiko Watanabe

    Published 2014-01-01
    “…We have been analyzing comprehensive expression patterns of microRNA in human and mouse embryonic stem and induced pluripotent stem cells. …”
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  12. 27512

    Intelligent Target Detection in Synthetic Aperture Radar Images Based on Multi-Level Fusion by Qiaoyu Liu, Ziqi Ye, Chenxiang Zhu, Dongxu Ouyang, Dandan Gu, Haipeng Wang

    Published 2025-01-01
    “…Decision-level fusion based on DST can not only consolidate complementary strengths in different models but also incorporate human or expert involvement in proposition for guiding effective decision making. …”
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  13. 27513

    The Deconstruction of Modern Mortality of Death: An Analysis Through Law, War, and Social Philosophy by Tomasz Wierzchowski, Bożena Iwanowska, Dawid Stadniczeńko, Yan Kapranov

    Published 2024-12-01
    “…Material and methods A qualitative analysis is conducted through a review of international legal frameworks, including the Universal Declaration of Human Rights and the International Covenant on Civil and Political Rights. …”
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  14. 27514

    Purposefulness and spontaneity as properties of self-organization of thinking by Denis F. Dautov, Alla K. Belousova

    Published 2022-07-01
    “…Attention is drawn to the correlation of the conscious and unconscious in the human psyche, with the manifestations of verbal and nonverbal components of thinking. …”
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  15. 27515

    Chloroplast DNA Diversity of Tunisian Barley Landraces as Revealed by cpSSRs Molecular Markers and Implication for Conservation Strategies by Marwa Snoussi, Leila Riahi, Mériam Ben Romdhane, Ahmed Mliki, Nejia Zoghlami

    Published 2022-01-01
    “…In Tunisia, barley local landraces are still cropped for human and animal consumption in some subsistence farming systems under marginal and stressed conditions. …”
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  16. 27516

    Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases [version 2; peer review: 2 approved] by Céline Heinl, Ines Schadock, Maximilian Wurm, Paul Lucas Wildner, Daniel Butzke, Bettina Bert, Alexandra Bannach-Brown, Matthias Steinfath, Kai Diederich

    Published 2024-11-01
    “…Maximizing translation should be central to animal research on human diseases, guiding researchers in study design and animal model selection. …”
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  17. 27517

    Z-Guggulsterone Induces Apoptosis in Gastric Cancer Cells through the Intrinsic Mitochondria-Dependent Pathway by Ruxi Lv, Min Zhu, Kun Chen, Haitao Xie, Hongxia Bai, Qingfa Chen

    Published 2021-01-01
    “…Materials and Methods. Human gastric tumor SGC-7901 cells and GES-1 normal epithelial cells were treated with z-guggulsterone (0–75 μM) for 24 h. …”
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  18. 27518

    Assessing and predicting Bojiang lake area and LULC changes from 2000 to 2045 by Muhammad Naeem, Yongqiang Zhang, Xiaoqiang Tian, Ping Miao, Congcong Li, Zhenwu Xu, Longhao Wang, Faisal Mumtaz, Zixuan Tang, Shaoyang He

    Published 2025-04-01
    “…Study focus: While the global significance of lake ecosystems is well established, few studies have investigated the long-term dynamics of Bojiang Lake, particularly the interplay between human activities and climate change. This study assesses lake area fluctuations and land use/land cover changes in the Bojiang Lake Basin from 2000 to 2023 and provides projections for 2024–2045 using the CA-ANN model. …”
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  19. 27519

    Ethnopharmacology, Biological Evaluation, and Chemical Composition of Ziziphus spina-christi (L.) Desf.: A Review by Mahmoud Dogara Abdulrahman, Ali Muhammad Zakariya, Harmand A. Hama, Saber W. Hamad, Sawsan S. Al-Rawi, Sarwan W. Bradosty, Ahmad H. Ibrahim

    Published 2022-01-01
    “…However, the safety and efficacy of Z. spina have not been wholly assessed in humans, and further well-designed clinical trials are needed to corroborate preclinical findings. …”
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  20. 27520

    High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma by Solenne Bourdier, Anne-Sophie Fisch, Keziban Merve Alp, Ridhima Das, Philipp Mertins, Ingeborg Tinhofer

    Published 2025-01-01
    “…Abstract Human papilloma virus-negative head and neck squamous cell carcinoma (HNSCC) frequently harbors 11q13 amplifications. …”
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