Community-based HPV self-collection versus visual inspection with acetic acid in Uganda: a cost-effectiveness analysis of the ASPIRE trial by Joel Singer, Angeli Rawat, Heather Armstrong, Josaphat Byamugisha, Gina S Ogilvie, Alex K Mezei, Heather N Pedersen, Stephen Sy, Catherine Regan, Sheona M Mitchell-Foster, Musa Sekikubo, Jane J Kim, Nicole G Campos

“…Community-based self-collected human papillomavirus (HPV) testing has been proposed to reduce barriers to screening.Objective Our objective was to evaluate the cost-effectiveness of the Advances in Screening and Prevention of Reproductive Cancers (ASPIRE) trial, conducted in Kisenyi, Uganda in April 2014 (n=500). …”
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Probabilistic nested model selection in pharmacokinetic analysis of DCE-MRI data in animal model of cerebral tumor by Hassan Bagher-Ebadian, Stephen L. Brown, Mohammad M. Ghassemi, Prabhu C. Acharya, Indrin J. Chetty, Benjamin Movsas, James R. Ewing, Kundan Thind

“…Sixty-six immune-compromised-RNU rats were implanted with human U-251 N cancer cells, and DCE-MRI data were acquired from all the rat brains. …”
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Factors associated with having a steady homosexual partner among men who have sex with men, based on internet recruitment by Peng Zhang, Weiyong Chen, Jing Li, Yun Fu, Fang Wang, Xing Wang, Zhongrong Yang

“…Multivariate logistic regression analysis showed that older participants having a steady HP (adjusted odds ratio [aOR]: 1.04; 95% confidence interval [CI]: 1.01–1.07)was associated with an average monthly income >6,000 Chinese yuan (aOR: 1.47; 95% CI: 1.01–2.16), a belief that using enhancers such as Rush Popper increases the human immunodeficiency virus (HIV) infection risk (aOR: 1.56; 95% CI: 1.02–2.41), identification as purely homosexual (aOR: 2.02; 95% CI: 1.37–2.99), having engaged in anal sex with a HP in the previous 6 months (aOR: 4.13; 95% CI:2.51–6.90), and knowing the HIV status of their HP (aOR: 1.88; 95% CI: 1.17–3.06). …”
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Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

“…In addition, melanoma mouse tumor immunotherapy models were performed to explore the synergistical efficacy of antitumor immunity via prevention of tumor-specific T cell senescence combined with anti-programmed death-ligand 1 (anti-PD-L1) checkpoint blockade therapy.Results We report that both mouse malignant tumor cells and Treg cells can induce responder T cell senescence, similar as shown in human Treg and tumor cells. Accumulated senescent T cells also exist in the TME in tumor models of lung cancer, breast cancer and melanoma. …”
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Snow depth estimation on leadless landfast ice using Cryo2Ice satellite observations by M. Saha, J. Stroeve, J. Stroeve, D. Isleifson, J. Yackel, V. Nandan, V. Nandan, J. C. Landy, H. M. Lam

“…<p>Observations of snow on Arctic Sea ice are vitally important for sea ice thickness estimation, bio-physical processes, and human activities. While previous studies have combined CryoSat-2- and ICESat-2-derived freeboards to estimate snow depth over Arctic sea ice, these approaches require leads within the ice pack to estimate the freeboard heights above the sea surface. …”
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Your period and your pregnancy, a cohort study of pregnant patients investigating the associations between menstruation and birth outcomes in Australia: study protocol by Miranda Davies-Tuck, Billie Bradford, Adrienne Gordon, Beverley Vollenhoven, Kirsten Rebecca Palmer, Kirstin Tindal, Caroline E Gargett, Fiona Cousins, Stacey Ellery

“…Participants will also be invited to complete an optional fetal movements survey at 28–32 and 36+ weeks’ gestation, and consent for placental collection at the time of birth will be sought.Ethics and dissemination Ethics approval was obtained from Monash Health Human Research Ethics Committee (83559) on 24 April 2024. …”
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NALCN expression is down-regulated and associated with immune infiltration in gastric cancer by Xuewei Li, Xuewei Li, Na Wu, Chen Wang, Beibei Pei, Xiaoyan Ma, Jun Xie, Jun Xie, Wenhui Yang

“…BackgroundNALCN has been identified as a tumor suppressor gene, and its role in human cancer progression has garnered significant attention. …”
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A phase 1b clinical trial to determine the safety, tolerability and immunogenicity of simian adenovirus and poxvirus vectored vaccines against Mycobacterium avium complex subspecie... by Jeremy Sanderson, Jeremy Aboagye, Rebecca Makinson, Katerina Rapi, Samuel Provstgaard-Morys, Lisa Stockdale, Alison Lawrie, Isabelle Lanigan, Nishat Halim, Abdel Douiri, Emily Greenlay, Rayka Malek, Emma Gray, Lindsey West, Fatima El Oulidi, Paul Ian Cross, Michael Stallibrass, Sarah C. Gilbert, Adrian V.S. Hill, Katie J. Ewer

“…The Sponsor was involved in protocol development, trial conduct, including data monitoring and analysis, and the preparation of this manuscript in line with the Medicines for Human Use (Clinical Trials) Regulations 2004 and amendments.…”
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High-resolution mapping of global winter-triticeae crops using a sample-free identification method by Y. Fu, X. Chen, C. Song, X. Huang, J. Dong, Q. Peng, W. Yuan

“…<p>Winter-triticeae crops, such as winter wheat, winter barley, winter rye and triticale, are important in human diets and are planted worldwide, and thus accurate spatial distribution information on winter-triticeae crops is crucial for monitoring crop production and food security. …”
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Power Transmission for Millimeter-Wave Indoor/Outdoor Wearable IoT Devices Using Grounded Coplanar Waveguide-Fed On-Body Antenna by Fuad Erman, Slawomir Koziel, Alhareth Zyoud, Leifur Leifsson, Ubaid Ullah, Shaker Alkaraki

“…A prototype of the proposed antenna is fabricated and validated experimentally for both cases on a human volunteer arm/chest and in the free space. …”
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Deciphering the therapeutic effects of Xiyanping injection: insights into pulmonary and gut microbiome modulation, SerpinB2/PAI-2 targeting, and alleviation of influenza a virus-in... by Tengwen Liu, Shuping Li, Xuerui Wang, Mingjiang Liu, Yuchen Wang, Jie Ying, Shuwen Zhang, Yan Lin, Ning Wang, Yungjing Bai, Lan Xie, Tengfei Chen, Quansheng Feng, Xiaolong Xu

“…KEGG pathway analysis indicated significant modifications in genes associated with influenza A, mitogen-activated protein kinase signaling, nuclear factor kappa-B signaling, and apoptosis following XYP injection. Finally, human protein chips and molecular docking were carried out to confirm the binding of the main component of XYP injection, andrographolide, with SERPINB2/PAI-2 protein. …”
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Co-Infection of <i>Culex tarsalis</i> Mosquitoes with Rift Valley Fever Phlebovirus Strains Results in Efficient Viral Reassortment by Emma K. Harris, Velmurugan Balaraman, Cassidy C. Keating, Chester McDowell, J. Brian Kimble, Alina De La Mota-Peynado, Erin M. Borland, Barbara Graham, William C. Wilson, Juergen A. Richt, Rebekah C. Kading, Natasha N. Gaudreault

“…Rift Valley fever phlebovirus (RVFV) is a zoonotic mosquito-borne pathogen endemic to sub-Saharan Africa and the Arabian Peninsula which causes Rift Valley fever in ruminant livestock and humans. Co-infection with divergent viral strains can produce reassortment among the L, S, and M segments of the RVFV genome. …”
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Safety and efficacy of intravenous thrombolysis: a systematic review and meta-analysis of 93,057 minor stroke patients by Mostafa Hossam El Din Moawad, Talal Salem, Anas Alaaeldin, Youssef Elaraby, Peter D. Awad, Amr Ahmed Khalifa, Ahmed El Naggar, Khaled Ashraf Mohamed, Mohamed Elhalal, Mostafa Badr, Ramy Abdelnaby

“…Intravenous thrombolysis (IVT) is a crucial treatment option for acute ischemic stroke (AIS) including: alteplase, recombinant human tissue-type plasminogen activator (r-tPA), and the recently approved tenecteplase. …”
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Synthesis of novel titania nanoparticles using corn silky hair fibres and their role in developing a smart restorative material in dentistry by Afsheen Mansoor, Emaan Mansoor, Ezza Mansoor, Efrah Mansoor, Atta Ullah Shah, Uzma Asjid, João Filipe Brochado Martins, Sami Ullah Khan, Paulo J. Palma

“…Objectives: The oral healthcare sector is witnessing a significant increase in the creation of eco-friendly biomaterials intended to inflict minimal damage to humans and the environment, primarily due to the inadequacies of conventional synthetic restorative materials which have a short shelf life and are prone to instability. …”
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Associations of HLA-G 3’UTR polymorphisms and increased HLA-G expression with gastric cancer susceptibility and prognosis by Ines Zemni, Daria Bortolotti, Sabrine Dhouioui, Sana Baroudi, Malek Ferjani, Inès Nasri, Yosr Zenzri, Md Ataur Rahman, Abdel Halim Harrath, Roberta Rizzo, Nadia Boujelbene, Inès Zidi

“…The aim of the current study was to examine the relationship between Human leukocyte antigen (HLA)-G 3’UTR polymorphisms and the expression of HLA-G in both tumor tissues and plasma samples from patients with GC in the Tunisian population. …”
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Distribution of Major HLA-A, -B, -DR, and -DQ Loci Potentially Associated with Multiple Sclerosis in a Healthy Population from Southern Morocco by Abir Fguirouche, Fatimazahra Ouahmani, Ikram Brahim, Raja Hazime, Nissrine Louhab, Najib Kissani, Mohamed Chraa, Brahim Admou

“…<b>Background:</b> Many factors contribute to the development and the progression of Multiple Sclerosis (MS), including Human Leukocyte Antigen (HLA) molecules. Some of them are considered as predisposing, like DRB1*15, DRB1*13, DRB1*03, DRB1*04, DQB1*06, DQB1*02, while HLA A2, HLA B44, DRB1*11, and DRB1*12 are rather considered as protective. …”
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Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract by Chun-Nun Chao, Chi-Feng Hung, Wei‑Hong Lai, Chun-Liang Tung, Wan-Yun Yeh, Kai-Wu Yang, Meilin Wang, Ya-Yan Lai, Pei-Lain Chen, Cheng-Huang Shen

“…Abstract Background Human polyomaviruses (HPyVs), JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV), have been found in upper tract urothelial carcinoma UTUC; however, the association of the viral oncogenic factors and clinical characteristics of UTUC remains unclear. …”
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A synthesis of academic literature on eco-spirituality by A.H.A. Adow, M.M. Safeer, M.G.H. Mohammed, M. Sayeed Alam, M.M. Sulphey

“…By synthesizing existing evidence and highlighting avenues for future research, it contributes to ongoing discussions on the role of spirituality in shaping human interactions with the natural world, ultimately empowering individuals and communities to enact meaningful change and promote a more harmonious relationship with the planet.…”
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Neuronal cell type specific roles for Nprl2 in neurodevelopmental disorder-relevant behaviors by Brianne Dentel, Lidiette Angeles-Perez, Abigail Y. Flores, Katherine Lei, Chongyu Ren, Andrea Pineda Sanchez, Peter T. Tsai

“…These phenotypes enhance understanding of the spectrum of disease found in human populations with GATOR1 loss of function and highlight the significance of distinct cellular populations to NDD-related behaviors. …”
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Systematic collection, annotation, and pattern analysis of viral vaccines in the VIOLIN vaccine knowledgebase by Anthony Huffman, Mehul Gautam, Arya Gandhi, Priscilla Du, Lauren Austin, Kallan Roan, Jie Zheng, Yongqun He, Yongqun He

“…., viral entry, assembly, exit, and immune evasion) as identified in top ranked human, animal vaccines, and HPV vaccines. The vaccine antigen proteins also show up in different virion locations in viruses such as HRSV vaccines. …”
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