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25721
655Val and 1170Pro ERBB2 SNPs in Familial Breast Cancer Risk and BRCA1 Alterations
Published 2007-01-01“…Human ERBB2 presents several SNPs. One of these, Ile655Val, introduces a structural change in the transmembrane region of ERBB2 and has been the focus of debate over its potential role as a susceptibility marker for breast cancer risk. …”
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25722
A Push on Job Anxiety for Employees on Managing Recent Difficult to Understand Computing Equipment in the Modern Issues in Indian Banking Quarter
Published 2015-01-01“…Stress management can be defined as intervention planned to decrease the force of stressors in the administrative center. These can have a human being focus, aimed at raising an individual’s ability to cope with stressors and the implementation of the CRM is essential to establish a better performance of the banking sector. …”
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25723
Secretory phospholipase A2 inhibitory activity in Tragia hispida: A novel and promising therapeutic agent for dengue fever
Published 2025-02-01“…Furthermore, THB exhibited significant inhibition of sPLA2 activity in human serum from dengue patients (n = 31, p < 0.0001) than that exhibited by CAY 10590. …”
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25724
Landslide susceptibility assessment for Uttarakhand, a Himalayan state of India, using multi-criteria decision making, bivariate, and machine learning models
Published 2025-01-01“…Uttarakhand, with its unique topographical and hydrological conditions, unplanned human settlements, and changing precipitation patterns, is highly susceptible to landslides. …”
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25725
Results of a modified Delphi consensus on the optimal testing pathway for oesophago-gastric cancer care in the UK
Published 2025-02-01“…Given the level of agreement and that the stopping criteria were met, it was decided not to undertake further Delphi rounds.Conclusion The recommendations support the use of a reflex testing approach for human epidermal growth factor receptor 2, programmed death ligand 1 and microsatellite instability high/mismatch repair deficiency in patients diagnosed with OG cancer who are suitable for treatment with targeted therapy.…”
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25726
Effect of Kinases in Extracellular Vesicles from HIV-1-Infected Cells on Bystander Cells
Published 2025-01-01“…As of 2023, there were 39.9 million people living with Human Immunodeficiency Virus type 1 (HIV-1). Although great strides have been made in treatment options for HIV-1, and our understanding of the HIV-1 life cycle has vastly improved since the start of this global health crisis, a functional cure remains elusive. …”
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25727
Migration patterns of oil leakage from underground oil depots on coral islands and reefs, and its impact on freshwater lenses
Published 2025-01-01“…Amid the increasing scarcity of terrestrial resources, the vast resource potential of the marine environment has accelerated human exploration and exploitation of the ocean. …”
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25728
Bullatine A suppresses glioma cell growth by targeting SIRT6
Published 2025-01-01“…In this study, we investigated the effects of BLA on human brain malignant glioblastoma cells. Our results showed that BLA inhibited the proliferation of U87MG and U251 cells in a dose-dependent manner and decreased their survival rate. …”
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25729
Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells
Published 2017-01-01“…One recent example targeted the virus-encoded G protein-coupled receptor US28 as a strategy for specific and efficient treatment of human cytomegalovirus (HCMV) infections. US28 is expressed on virus-infected cells and scavenge chemokines by rapid internalization. …”
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25730
Classification, Processing Procedures, and Market Demand of Chinese Biscuits and the Breeding of Special Wheat for Biscuit Making
Published 2022-01-01“…Biscuits are composed of four main ingredients, which are flour, fat/oil, sugar, and water, whereas several secondary ingredients also are important sources of high molecular carbohydrates, plant proteins, vitamins, and minerals for human beings. In this study, we systematically summarized the related research of biscuits, including the main types of China’s biscuits, the market demands, and statistics of wheat planting, production, and import in recent ten years, as well as the research of soft wheat breeding for biscuit. …”
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25731
Clinicopathological characteristics and long-term prognosis of triple-negative breast cancer patients with HER2-Low expression: a retrospective propensity score-matched cohort stud...
Published 2024-12-01“…Abstract Purpose The objective of the current research was to assess the clinicopathological characteristics and long-term prognosis of triple-negative breast cancer (TNBC) patients with human epidermal growth factor receptor 2 (HER2)-low status following breast surgery. …”
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25732
Clinical Characteristics and Short-Term Outcomes of HIV Patients Admitted to an African Intensive Care Unit
Published 2016-01-01“…In high-income countries, improved survival has been documented among intensive care unit (ICU) patients infected with human immune deficiency virus (HIV). There are no data from low-income country ICUs. …”
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25733
Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping Review
Published 2025-01-01“… BackgroundGender is known to have a strong influence on human health and disease. Despite its relevance to treatment and outcome, gender is insufficiently considered in current health research. …”
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25734
Interleukin-6 related signaling pathways as the intersection between chronic diseases and sepsis
Published 2025-01-01“…This article summarized the inflammatory mechanisms of IL-6 cross-talked with other mediators of some chronic diseases in vitro, animal models, and human experiments, leading to the activation of pathways and accelerating the progression of sepsis. …”
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25735
Selective Activation of Cancer Stem Cells by Size-Specific Hyaluronan in Head and Neck Cancer
Published 2015-01-01“…We determined that human head and neck cancer cells (HSC-3 cell line) contain a subpopulation displaying cancer stem cell (CSC) properties and are very tumorigenic. …”
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25736
Projecting Surface Water Area Under Different Climate and Development Scenarios
Published 2024-07-01“…However, most projections of surface water dynamics focus on climate drivers using local‐scale hydrological models, with few studies accounting for climate and human drivers such as land‐use/land‐cover change. …”
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25737
Unified Visual-Aware Representations for Data Analytics
Published 2025-01-01“…The visual representations serve for data analytics tasks performed by human users as well as serve for universal data representations used in machine learning models for automated tasks. …”
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25738
Corrosion behavior of NiTi alloys fabricated by laser powder bed fusion in relation to the formed passive films in Hank's solution
Published 2025-01-01“…Varying the parameters of the L-PBF process may result in the NiTi alloys with different ratios of B2 and B19′ phases, thereby, the different corrosion performance in the human body. However, a dearth of research efforts remains dedicated to resolving this issue. …”
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25739
A systematic review of neurological symptoms and brain abnormalities in SARS-CoV-2 infections
Published 2023-08-01“… The aim of this systematic review is to show some clear evidence of COVID-19 infections in the human brain and draw attention to the neurological symptoms that were described during the early stages of the pandemic. …”
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25740
Dredging and sediment discharge in a river with floodplain. Physicochemical and microbiological effects in Paraná river
Published 2025-01-01“…Alterations caused by human activities in the environment, such as dredging, modify the physicochemical conditions and affect the habitat. …”
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