Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex by Harald Bernhard, Hana Petržílková, Barbora Popelářová, Kamil Ziemkiewicz, Karolina Bartosik, Marcin Warmiński, Laura Tengo, Henri Gröger, Luciano G. Dolce, Cameron D. Mackereth, Ronald Micura, Jacek Jemielity, Eva Kowalinski

“…Abstract Kinetoplastids are a clade of eukaryotic protozoans that include human parasitic pathogens like trypanosomes and Leishmania species. …”
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Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes by Daniel Espes, Mats Martinell, Per-Ola Carlsson

“…Future studies are clearly needed to delineate the exact role, if any, of betatrophin in regulating human beta-cell mass.…”
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Dynamics of <i>Nakaseomyces glabratus</i> biofilm formation by E. M. Lenchenko, N. P. Sachivkina, A. V. Liseitsev

“…Formation of biofilms of microorganisms, including those of Nakaseomyces glabratus, is responsible for the development of local and systemic pathologies in humans and animals. The system of gene expression coordination (quorum sensing) in the representation of signaling molecules allows regulation of the amount and composition of biofilm populations thus expanding the adaptive capacity of microorganisms. …”
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Identification of innovation drivers based on technology-related news articles by Albina Latifi, David Lenz, Peter Winker

“…However, given that the rate of false alarms is not negligible, at the end also human judgement is needed when using this approach.…”
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Effects of reproductive technologies and SPF status on some physiological and behavioral characteristics in rats with arterial hypertension (ISIAH strain) by D. S. Ragaeva, T. O. Abramova, I. N. Rozhkova, E. Yu. Brusentsev, E. V. Kalinichenko, T. N. Igonina, S. Ya. Amstislavsky

“…On the other hand, assisted reproductive technologies (ART) are widely used in modern medicine for human infertility treatment as well as for genome resource banking. …”
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Evaluation the efficiency of using Artificial Neural Networks in predicting meteorological droughts in north-west of Iran by Arash malekian, mahro dehbozorgi, Amir hoshang ehsani

“…Drought is one of the most destructive natural disasters in human societies that cause irreparable impacts on agriculture, environment, society and economics. …”
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Mast Cell Activation Syndrome in COVID-19 and Female Reproductive Function: Theoretical Background vs. Accumulating Clinical Evidence by Dariusz Szukiewicz, Piotr Wojdasiewicz, Mateusz Watroba, Grzegorz Szewczyk

“…Coronavirus disease 2019 (COVID-19), a pandemic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, can affect almost all systems and organs of the human body, including those responsible for reproductive function in women. …”
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N7-methylguanosine modification in cancers: from mechanisms to therapeutic potential by Qihui Wu, Xiaodan Fu, Guoqian Liu, Xiaoyun He, Yimin Li, Chunlin Ou

“…Their influence on the synthesis and processing of messenger RNA, ribosomal RNA, and transfer RNA allows m7G modifications to affect diverse cellular, physiological, and pathological processes. m7G modifications are pivotal in human diseases, particularly cancer progression. …”
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Chitosan suitability to adhesion, neuronal differentiation and maturation of hiPSCs compared to Matrigel coated substrates by Sara Grasselli, Donatella Di Lisa, Pier Francesco Ferrari, Sergio Martinoia, Laura Pastorino

“…Human induced pluripotent stem cells (hiPSCs) derived neurons are revolutionising the study of patient-specific conditions. …”
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Ethanol Disrupts the Protective Crosstalk Between Macrophages and HBV-Infected Hepatocytes by Murali Ganesan, Anup S. Pathania, Grace Bybee, Kusum K. Kharbanda, Larisa Y. Poluektova, Natalia A. Osna

“…This study was performed on HBV-replicating HepG2.2.15 cells and human monocyte-derived macrophages (MDMs). We found that exposure of HepG2.2.15 cells to an acetaldehyde-generating system (AGS) increased HBV RNA, HBV DNA, and cccDNA expressions and suppressed the activation of ISGs, <i>APOBEC3G</i>, <i>ISG15</i>, and <i>OAS1</i>. …”
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Exploring the effects of gut microbiota on cholangiocarcinoma progression by patient-derived organoids by Ann-Kathrin Lederer, Nele Görrissen, Tinh Thi Nguyen, Clemens Kreutz, Hannah Rasel, Fabian Bartsch, Hauke Lang, Kristina Endres

“…Organoids are 3D cell models cultivated in a modifiable and controlled condition, which can be grown from tumor tissue. 3D cell models are able to imitate physiological and pathological processes in the human body and thus contribute to a better understanding of health and disease. …”
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Detection of Jihadism in Social Networks Using Big Data Techniques Supported by Graphs and Fuzzy Clustering by Cristina Sánchez-Rebollo, Cristina Puente, Rafael Palacios, Claudia Piriz, Juan P. Fuentes, Javier Jarauta

“…Future applications are not limited to detecting terrorist activism. Human resources departments can apply the power of profile identification to automatically classify candidates, security teams can detect undesirable clients in the financial or insurance sectors, and immigration officers can extract additional insights with these techniques.…”
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Toll-like receptor 1/2 activation reduces immunoglobulin free light chain production by multiple myeloma cells in the context of bone marrow stromal cells and fibronectin. by Jahan Abdi, Frank Redegeld

“…This study explored the effect of TLR1/2 ligand (Pam3CSK4) alone or combined with bortezomib (BTZ) on production of FLCs in human myeloma cell lines, L363, OPM-2, U266 and NCI-H929. …”
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Research on the Decision Mechanism of University-Enterprise Collaborative Innovation Based on Quantum Cognition by Sheng-Yuan Wang, Wan-Ming Chen, Ying Liu, Xiao-Lan Wu

“…The relationship between quantum cognition and decision-making is an important field in the direction of human behavior research. The uncertain and entangled state of quantum cognition has largely explained the decision-making process with limited information and ambiguity. …”
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Public and Service Activity of the Ministry of Internal Affairs of Ukraine: Current Issues by O. V. Dzhafarova, O. O. Mozhovyi

“…It has been emphasized that the content of public and service activity of the Ministry of Internal Affairs of Ukraine is: a) a separate function of the service state, the content of which is to change the ideology, forms and methods in the work of law enforcement agencies; b) one of the externally-oriented functions of a specially created state institution along with such functions as regulatory, supervisory and law enforcement, c) the basis for the authorized entity to implement the tasks and functions of the state to ensure human rights and freedoms, as well as the interests of society and the state, keeping public order and security, combating crime, d) high-quality and affordable provision of administrative services to specific individuals in the form of licensing, registration and other similar actions in the law enforcement sphere.…”
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Evaluation of DNA Damage in Common Carp (Cyprinus carpio L.) by Comet Assay for Determination of Possible Pollution in Lake Mogan (Ankara) by İsmet Çok, Onur Kenan Ulutas, Öncü Okusluk, Emre Durmaz, Nilsun Demir

“…Contamination of the aquatic environment with various concentrations of pollutants results in unexpected threats to humans and wildlife. The consequences of exposure and metabolism of pollutants/xenobiotics, especially carcinogens and mutagens, can be suitably assessed by investigating severe events, such as DNA damage; for example, DNA adducts and DNA strand breaks. …”
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The circular economy, 5R framework, and green organic practices: pillars of sustainable development and zero-waste living by Kshitij K. Meshram

“…The pillars of SDGs prevent potential destructive impacts on the environment and human health. They promote green-organic domain practices to obtain a more sustainable economy, addition to boosting quality of life by harmonizing disturbed climate change. …”
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Monitoring Disease Progression and Therapeutic Response in a Disseminated Tumor Model for Non-Hodgkin Lymphoma by Bioluminescence Imaging by Margarethe Köberle, Kristin Müller, Manja Kamprad, Friedemann Horn, Markus Scholz

“…By stably transfecting a luciferase expression vector, we created two bioluminescent human non-Hodgkin lymphoma cell lines, Jeko1(luci) and OCI-Ly3(luci), that are CD20 positive, a prerequisite to studying rituximab, a chimeric anti-CD20 antibody. …”
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Poética de los Valores y sus metáforas by Francisco das Chagas Amorim de Carvalho

“…The art of cultivating good words also contributes to the cultivation of humanity.…”
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Study protocol for a multi-center stepped-wedge cluster randomized trial to explore the usability and outcomes among young people living with HIV in Kiambu and Kirinyaga counties o... by Eric Nturibi, Jared Mecha, Elizabeth Kubo, Albert Orwa, Florence Kaara, Faith Musau, Christine Wamuyu, Justus Kilonzi, Randeep Gill, Sanne Roels

“…While the incidence of Human Immunodeficiency Virus (HIV) infection is decreasing in most age groups worldwide, it is rising among adolescents and young adults, who also face a higher rate of HIV-related deaths. …”
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