Transcriptomic Profiling and Tumor Microenvironment Classification Reveal Unique and Dynamic Immune Biology in HIV-Associated Kaposi Sarcoma by Jihua Yang, Ayse Ece Cali Daylan, Aleksei Shevkoplias, Ekaterina Postovalova, Meng Wang, Andrey Tyshevich, Matthew Lee, Hiba Narvel, Ksenia Zornikova, Nara Shin, Nikita Kotlov, Luca Paoluzzi, Changcheng Zhu, Balazs Halmos, Xingxing Zang, Haiying Cheng

“…Kaposi Sarcoma (KS) is a vascular tumor originating from endothelial cells and is associated with human herpesvirus 8 (KSHV) infection. It disproportionately affects populations facing health disparities. …”
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Green Tea Extract (<i>Theaceae</i>; <i>Camellia sinensis</i> L.): A Promising Antimicrobial, Anti-Quorum Sensing and Antibiofilm Candidate Against Multidrug-Resistant <i>Campylobac... by Mona S. Emara, Ahmed M. Ammar, Ashraf M.O. Abdelwahab, Attia A. Elgdawy, Adel Abdelkhalek, Elena Pet, Gabi Dumitrescu, Mirela Ahmadi, Norhan K. Abd El-Aziz

“…Many studies have been carried out to explore innovative and alternative strategies to control antibiotic-resistant campylobacters in animal reservoirs and human hosts; however, limited studies have been performed to develop efficient control schemes against <i>Campylobacter</i> biofilms. …”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…This was parallel to laboratory molecular investigations of in vitro GABAergic neurons derived from induced human pluripotent stem cells (hiPSCs) of SSADHD subjects and biochemical analyses performed on a versatile murine model that uses an inducible and reversible rescue strategy allowing on-demand and cell-specific gene therapy. …”
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Characteristics and real-world medication persistence of people living with HIV treated with DTG/3TC or BIC/FTC/TAF: a hospital claims database study in Japan by Rie Kanamori, Nozomi Aoki, Akio Kanazawa, Mayumi Yuda, Nao Makino, Emi Ohata, Nobuyuki Fukui, Hirotake Mori, Hirohide Yokokawa, Toshio Naito

“…BackgroundAs the life expectancy of people living with human immunodeficiency virus (HIV) (PLWH) has improved, chronic disease burden and polypharmacy have increased in PLWH. …”
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The CYP4/20-HETE/GPR75 axis in the progression metabolic dysfunction-associated steatosis liver disease (MASLD) to chronic liver disease by James P. Hardwick, Byoung-Joon Song, Paul Rote, Charles Leahy, Yoon Kwang Lee, Alexandra Rudi Wolf, Danielle Diegisser, Victor Garcia

“…This work illustrates key correlations associated with the CYP4/20-HETE/GPR75 axis and the progression of liver disease in humans.…”
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CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma by Laura M. Moser, Laura M. Moser, Laura M. Moser, Laura M. Moser, Laura M. Moser, Catrin Heim, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Philipp Wendel, Philipp Wendel, Philipp Wendel, Philipp Wendel, Süleyman Bozkurt, Sabine Harenkamp, Hermann Kreyenberg, Hermann Kreyenberg, Michael Merker, Michael Merker, Christian Münch, Christian Münch, Christian Münch, Elise Gradhand, Meike Vogler, Meike Vogler, Meike Vogler, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Halvard Bönig, Halvard Bönig, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Peter Bader, Peter Bader, Peter Bader, Peter Bader, Peter Bader, Winfried S. Wels, Winfried S. Wels, Winfried S. Wels, Eva Rettinger, Eva Rettinger, Eva Rettinger, Eva Rettinger, Eva Rettinger

“…Efficacy was assessed in human ErbB2+ RMS cancer cell lines and primary patient samples in vitro and ex vivo using cytotoxicity and spheroid co-incubation assays. …”
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Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults by Jung Hyuk Lee, Yuna Shin, Kwang-Soo Shin, Ju Yeon Park, Mi Sun Kim, Young-Shin Park, Wuhyun Kim, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Chang-Yuil Kang, Sang Hwan Seo, Jae-Ouk Kim, Deok Ryun Kim, Nathaniel S. Hwang, Jae Seung Yang, Jerome H. Kim, Byoung-Shik Shim, Manki Song

“…ABSTRACT AdCLD-CoV19-1, a chimeric adenovirus-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, was previously reported to elicit robust antibody responses in mice and non-human primates after a single dose. In this study, we conducted a systems serology analysis to investigate changes in humoral immune responses induced by varying doses of the AdCLD-CoV19-1 vaccine in a phase I clinical trial. …”
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Seasonal analysis of indoor and outdoor ratios of PM2.5 and PM10 in Bangkok and Chiang Mai: A comparative study of haze and non-haze episodes by Wissanupong Kliengchuay, Sarima Niampradit, Narut Sahanavin, William Mueller, Susanne Steinle, Miranda Loh, Helinor Jane Johnston, Sotiris Vardoulakis, San Suwanmanee, Walaiporn Phonphan, John W. Cherrie, Kraichat Tantrakarnapa

“…Particulate matter (PM) air pollution has been identified as one cause of human health impact with the estimated global 8.8 million attributable deaths. …”
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Brucella suis ΔmapB outer membrane vesicles as an acellular vaccine against systemic and mucosal B. suis infection by Florencia Muñoz González, Florencia Muñoz González, Magali G. Bialer, Maria L. Cerutti, Silvia M. Estein, Lila Y. Ramis, Pablo C. Baldi, Pablo C. Baldi, Ángeles Zorreguieta, Ángeles Zorreguieta, Mariana C. Ferrero, Mariana C. Ferrero

“…Currently, there are no available human or porcine vaccines to protect against B. suis infection, which is primarily acquired through the mucosa. …”
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Experimental evidence-based construction of electroacupuncture for ischemic stroke: a meta-analysis and systematic review by Yaoguang Guo, Sihan Hu, Sihan Hu, Shiman Luo, Lang Tu, Yao Tang, Fang Zeng, Fang Zeng, Fang Zeng

“…These findings advocate for the integration of EA into stroke rehabilitation protocols and underscore the need for clinical trials to validate its efficacy in human subjects. Our study not only reinforces the therapeutic value of EA but also prompts further investigation into its underlying mechanisms, potentially guiding more effective stroke recovery strategies.…”
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High-fat diet promotes gestational diabetes mellitus through modulating gut microbiota and bile acid metabolism by Lei Yao, Xuefei Zhou, Xianqi Jiang, Hao Chen, Yuanliang Li, Xiao Xiong, Yan Tang, Haogang Zhang, Pengfei Qiao

“…Bile acids of serum, fecal samples from human and mice were analysised. Body weight, average feed intake, blood glucose, insulin levels and oral glucose tolerance test was performed among each groups. …”
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Transfer of aflatoxin M1 and sterigmatocystin from buffalo milk to soft cheeses by Maurizio Cossu, Andrea Sanna, Giannina Chessa, Stefano Sdogati, Ivan Pecorelli, Ilaria Di Marco Pisciottano, Sara Lambiase, Pasquale Gallo, Stefania Massafra, Elena Torres, Marilena Gili, Giovanni Lo Cascio, Antonio Vella, Roberto Condoleo, Bruno Neri, Guglielmo Militello, Gilberto Giangolini, Carlo Boselli

“…AFM1 is a toxic molecule classified by the IARC as “potentially carcinogenic to humans” in Group 1. In addition to the four aflatoxins (AFB1, AFB2, AFG1, and AFG2), these fungi also produce other toxins such as Sterigmatocystin (STC), while Aflatoxicol (AFL) is a metabolite of AFB1. …”
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Immunomodulatory and growth-promoting effects of Rauwolfia serpentina root powder in broiler chicks challenged with Salmonella Gallinarum by Yingyu Zhang, Hiba Rehman, Farina Khattak, Maryam Tariq, Bushra Nisar Khan, Sadia Chaman, Ayaesha Riaz, Muhammad Ovais Omer, Aqib Ali, Qamar un Nisa, Muhammad Muddassir Ali, Gulbeena Saleem

“…BackgroundAmid growing concern about antimicrobial resistance due to the irrational use of antibiotics in treating common poultry diseases, particularly Salmonella which is a foodborne pathogen in humans. This study investigates the effects of ethnoveterinary supplementation of Rauwolfia serpentina (L. …”
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Flood susceptibility mapping based on watershed geomorphometric characteristics and land use/land cover on a small island by B.H. Narendra, O. Setiawan, R.A. Hasan, C.A. Siregar, , Pratiwi, N. Sari, A. Sukmana, I.W.S. Dharmawan, R. Nandini

“…BACKGROUND AND OBJECTIVES: Flooding is the most frequent hydrological disaster which greatly impacts humans and the environment. Lombok, a small tropical island, experiences severe flooding almost yearly. …”
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Non-formal encounters between Israeli families and African immigrant families foster lifelong learning competence by Michal Ganz Meishar

“…Social implications – The non-formal encounters between the two groups of families create an atmosphere of equality: all are parents of children seeking to inculcate humane and social values. The collaborative atmosphere contributed to the understanding that closeness overpowers distance. …”
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Radiological safety assessment of sugar consumption in South Africa—a study of 226Ra, 228Ra, and 40K levels by Samuel Odumu Ogana John, Stephen Friday Olukotun, Stephen Friday Olukotun, Moses Mpofana Radebe, Manny Mathuthu

“…Human exposure to natural radionuclides in the environment primarily occurs through ingestion of foodstuffs, highlighting the importance of continuous monitoring of radionuclide levels in foodstuffs by ensuring consumer safety and compliance with regulatory standards. …”
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Prior Anticoagulation and Risk of Hemorrhagic Transformation in Acute Stroke: A Post Hoc Analysis of the PRODAST Study by Gerrit M. Grosse, Anika Hüsing, Andreas Stang, Nils Kuklik, Marcus Brinkmann, Martin Grond, Jens D. Rollnik, Lars Marquardt, Andrea Kraft, Eckhard Schlemm, Carsten Eggers, Christoph C. Eschenfelder, Christian Weimar, Hans‐Christoph Diener

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Changes in Microbial Safety and Quality of High-Pressure Processed Camel Milk by Tareq M. Osaili, Dinesh Kumar Dhanasekaran, Fayeza Hasan, Reyad S. Obaid, Anas A. Al-Nabulsi, Amin N. Olaimat, Leila Cheikh Ismail, Nadia Alkalbani, Mutamed Ayyash, Gafar Babatunde Bamigbade, Richard Holley, Adan Shahzadi Cheema, Wael Ahmad Bani Odeh, Khalid Abdulla Mohd, Ayesha Khalid Haji Kamal

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Identifikasi Gagal Ginjal Kronis dengan Mengimplementasikan Metode Support Vector Machine beserta K-Nearest Neighbour (SVM-KNN) by Alvin Tarisa Akbar, Novanto Yudistira, Achmad Ridok

“…Abstract Kidneys are a vital part for humans because they function to filter or clean the fluids we ingest so that they can be consumed safely. …”
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Effectiveness of the entomopathogenic fungus Alternaria murispora and the predatory ladybird Harmonia convergens in controlling Phenacoccus solenopsis (Tinsley) by Mohamed El Aalaoui, Said Rammali, Said Rammali, Fatima Zahra Kamal, Fatima Zahra Kamal, Gabriela Calin, Viorica Rarinca, Viorica Rarinca, Viorica Rarinca, Luminita Diana Hritcu, Alin Ciobică, Alin Ciobică, Alin Ciobică, Alin Ciobică, Mohamed Sbaghi

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