Functional Live-Cell Imaging Demonstrates that β-Integrin Promotes Type IV Collagen Degradation by Breast and Prostate Cancer Cells by Mansoureh Sameni, Julie Dosescu, Kenneth M. Yamada, Bonnie F. Sloane, Dora Cavallo-Medved

“…Here we conducted functional live-cell imaging in real time to investigate the effects of modulating β 1 -integrin expression and function on proteolytic remodeling of the extracellular matrix. Human breast and prostate cancer cells were grown on reconstituted basement membrane containing a quenched fluorescent form of collagen IV. …”
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Characterizing cell-type spatial relationships across length scales in spatially resolved omics data by Rafael dos Santos Peixoto, Brendan F. Miller, Maigan A. Brusko, Gohta Aihara, Lyla Atta, Manjari Anant, Mark A. Atkinson, Todd M. Brusko, Clive H. Wasserfall, Jean Fan

“…Finally, we apply CRAWDAD to SRO datasets of the human spleen to identify consistent as well as patient and sample-specific cell-type spatial relationships. …”
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Role of Interleukin- (IL-) 17 in the Pathogenesis and Targeted Therapies in Spondyloarthropathies by I-Tsu Chyuan, Ji-Yih Chen

“…Further evidence from human and animal studies have defined that IL-17 and IL-17-producing cells contribute to tissue inflammation, autoimmunity, and host defense, leading to the following pathologic events associated with SpA. …”
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Comprehensive analysis of poly(A) tails in mouse testes and ovaries using Nanopore Direct RNA Sequencing by Agnieszka Czarnocka-Cieciura, Michał Brouze, Natalia Gumińska, Seweryn Mroczek, Olga Gewartowska, Paweł S. Krawczyk, Andrzej Dziembowski

“…For instance, the defect of TENT5D causes infertility in humans. The data described here are generated mainly using the Oxford Nanopore Direct RNA Sequencing (DRS) method, which provides ground-truth information about mRNA molecules, including poly(A) tail length and nucleotide content. …”
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Dynamics of global economic growth: a Bayesian exploration of basic and augmented Solow models by Nguyen Thi My Diem, Nguyen Ngoc Thach

“…Specifically, strategies such as increasing investment, fostering technological innovation, enhancing human capital, and optimizing resource allocation should be prioritized to drive sustainable economic growth.…”
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An energy self-sustaining scheduling scheme for UAV delivery networks by XU Jia, YUAN Ming, WU Sixu, TAN Xin, LUO Jian

“…The unmanned aerial vehicle (UAV) delivery has become an effective supplement to vehicle delivery due to its low human cost, flexibility and convenience. However, UAVs are often limited by factors such as endurance and load capacity, requiring a low-cost and energy self-sustaining scheduling scheme for delivery and charging to support collaborative delivery of multiple UAVs. …”
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Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids by Martin Roumain, Giulio G. Muccioli

“…Finally, the method was successfully applied to the analysis of preclinical and clinical samples, quantifying 12 oxysterols and 14 bile acids in human plasma, 10 oxysterols and 18 bile acids in mouse plasma from the vena cava, and 10 oxysterols and 20 bile acids in mouse plasma from the portal vein within a single chromatographic run.…”
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Un climat de compétition : le changement climatique comme économie politique dans la fiction spéculative, 1889-1915 by Steve Asselin

“…In speculative fiction of the period, climate change occurs principally as a result of largescale human geoengineering projects aimed at transforming the world. …”
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Gamification: characteristics, trends, risks by A. P. Avdeeva, Yu. A. Safonova

“…The request for immersiveness is closely related to the human need to be the author of the “text”, to control the plot, to create a plurality of readings (hypertext). …”
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Gab Docking Proteins in Cardiovascular Disease, Cancer, and Inflammation by Yoshikazu Nakaoka, Issei Komuro

“…In addition, abnormal Gab protein signaling has been linked to human diseases including cancer, cardiovascular disease, and inflammatory disorders. …”
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Laser Irradiation Alters the Expression Profile of Genes Involved in the Extracellular Matrix In Vitro by Sandra M. Ayuk, Nicolette N. Houreld, Heidi Abrahamse

“…This study aimed to evaluate various genes involved in the ECM, in response to laser irradiation. Isolated human skin fibroblasts were used in three different cell models, namely, normal, normal wounded, and diabetic wounded. …”
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Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation by Jie Ruan, Xuxia Wei, Suizhi Li, Zijian Ye, Linyi Hu, Ru Zhuang, Yange Cao, Shaozhou Wang, Shengpeng Wu, Dezhi Peng, Shangwu Chen, Shaochun Yuan, Anlong Xu

“…Here, we found that Apaf-1-like molecules from lancelets, fruit flies, mice, and humans have conserved DNA sensing functionality. Mechanistically, mammalian Apaf-1 recruits receptor-interacting protein 2 (RIP2, also known as RIPK2) via its WD40 repeat domain and promotes RIP2 oligomerization to initiate NF-κB-driven inflammation upon cytoplasmic DNA recognition. …”
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Coupling adaptation mode and regulation strategy for the wind–thermal climate environment of vernacular dwellings in Jiangnan, China based on regional bioclimatic evaluation by Tianyi Min, Tong Zhang

“…As native building types, vernacular dwellings present the mode of human – environment mutualism, which is an important reference for responding to low-carbon and sustainable development of buildings and reshaping regional architectural styles. …”
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Salivary biomarkers in cancer - A narrative review by R. Swaathi, Madhu Narayan, Rajkumar Krishnan

“…Cancer remains as the most persistent disease among human population and is one of the leading causes of morbidity and mortality worldwide. …”
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Drivers’ Interaction with Adaptive Cruise Control on Dry and Snowy Roads with Various Tire-Road Grip Potentials by Ioana Koglbauer, Jürgen Holzinger, Arno Eichberger, Cornelia Lex

“…A future adaptation of ACC’s control strategy to reduced tire-road grip potential would not only improve comfort and user acceptance of the human driver but also increase the potential to react in emergency situations with braking or evasive steering.…”
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Comparative Analysis of Pre-trained based CNN-RNN Deep Learning Models on Anomaly-5 Dataset for Action Recognition by Fayaz Ahmed Memon, Umair Ali Khan, Pardeep Kumar, Imtiaz Ali Halepoto, Farida Memon

“… Action recognition in videos is one of the essential, challenging and active area of research in the field of computer vision that adopted in various applications including automated surveillance systems, security systems and human computer interaction. In this paper, we present an in-depth comparative analysis of five CNN-RNN models based on pre-trained networks such as InceptionV3, VGG16, MobileNetV2, ResNet152V2 and InceptionResNetV2 with recurrent LSTM units for action recognition on Anomaly-5 dataset. …”
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Cranial Cruciate Ligament Desmotomies in Sheep Resulting in Peroneus Tertius Injury by Peter J. Welsh, Crystal G. Collier, Holly M. Clement, Michael N. Vakula, Jeffrey B. Mason

“…Traditionally performed in rats, rabbits, cats, and dogs, CCLD in sheep provides an opportunity to study the pathology and treatment of joint instability in a species whose stifle better represents the equivalent human femorotibial joint. The surgical approaches for CCLD in sheep are variable and can result in inconsistent outcomes. …”
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Inclusive Education and Physical Education in Spain: A Qualitative Analysis of Teachers’ Perspectives by Pablo Saiz-González, Sara de la Fuente-González, Jacob Sierra-Díaz, Pablo Uría-Valle

“…This study underscores the need for ongoing, discipline-specific training for physical education teachers, supported by strong institutional commitments to ensure the provision of adequate human and material resources. Without such support, the burden on teachers remains disproportionate and ultimately unfair, hindering progress towards a truly inclusive educational environment.…”
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Rancher Perceptions of the Coyote in Florida by Raoul K. Boughton, Bethany Wright, Martin B . Main

“…As coyotes become a fixture of the Florida landscape, potential grows for conflict with humans. Coyotes are in Florida to stay, and understanding the agricultural community’s perception of their influence on livestock and wildlife is important to developing effective policies for coyote management. …”
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Delaware Inland Bays and Market Oyster (Crassostrea virginica) Quality for Consumption by Gulnihal Ozbay, Lathadevi Karuna Chintapenta, Talaysha Lingham, Stephen Lumor, Jung-lim Lee, Bettina Taylor, Shobha Sriharan, Samuel Besong

“…Ensuring seafood safety for human consumption is always a concern. Since oysters are consumed raw, disease causing organisms, environmental contaminants, toxins, chemicals, and even physical hazards such as soils and metals retained in the oysters can enter through feeding. …”
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