Selective epithelial expression of KRASG12D in the Oncopig pancreas drives ductal proliferation and desmoplasia that is accompanied by an immune response by Carlos P. Jara, Al-Murtadha Al-Gahmi, Audrey Lazenby, Michael A. Hollingsworth, Mark A. Carlson

“…These findings highlight the potential for site-specific activation of oncogenes in large animal models of epithelial tumors, with the ability to induce stromal alterations reminiscent of human PDAC.…”
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Molecular Epidemiology and Antimicrobial Resistance of Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella pneumoniae in Retail Cattle Meat by Nasrin Akter Liza, Hemayet Hossain, Md. Shahidur Rahman Chowdhury, Jarin Al Naser, Rayhan Mahmud Lasker, Asikur Rahman, Md. Ariful Haque, Md. Al Mamun, Md. Mukter Hossain, Md. Mahfujur Rahman

“…Enterobacteriaceae that produce extended-spectrum β-lactamases (ESBLs) can result in severe human infections, contributing to the development of complex diseases. …”
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Design Considerations of Online Infertility Prevention Training (OIPT): Development and Evaluation by Bahar Baran, Sirin Nur Yaci, Murat Ocal, Digdem Muge Siyez

“…In addition, while teaching concrete parts of the human body, interactive animations and visuals may be useful to motivate and increase engagement students to use the content again and again. …”
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Effective Connectivity Study Guiding the Neuromodulation Intervention in Figurative Language Comprehension Using Optical Neuroimaging by Tania Alexandra Couto, Shiyang Xu, Paulo Armada da Silva, Chenggang Wu, Karl Neergaard, Meng-Yun Wang, Juan Zhang, Yutao Xiang, Zhen Yuan

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Mechanistic insights into pachymic acid’s action on triple-negative breast Cancer through TOP2A targeting by Ming Liu, Li Zheng, Yang Zhang, Jinhui Tian

“…Abstract Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen and progesterone receptors, and lack of human epidermal growth factor receptor 2 (HER2) expression. …”
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Total Phenolic, Flavonoid Contents, and Antioxidant Activities of Fruit, Seed, and Bark Extracts of Zanthoxylum armatum DC by Nirmala Phuyal, Pramod Kumar Jha, Pankaj Prasad Raturi, Sangeeta Rajbhandary

“…These plants contain polyphenols and flavonoids that act as free radical scavengers and reduce oxidative stress and may be an alternative remedy to cure various harmful human diseases. This study aims to quantify the total phenolic and flavonoid contents (TPC and TFC) and antioxidant properties of methanol extracts of fruits, seeds, and bark of an important medicinal and aromatic plant, Zanthoxylum armatum collected from wild and cultivated populations in Nepal. …”
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Prevalence of root caries in relation to various risk factors in a sample of subjects aged (25-64) years in Erbil city: A cross sectional study by Tara Kamal Talib, Vian Omer Majeed

“… Backgrounds: Root surface caries is a significant oral public health problem among humans' due to improvements in health care, long life expectancy, and increasing demand to maintain oral health. …”
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Digital Health Intervention (SANGYAN Podcast) to Enhance Knowledge Related to COVID-19 and Other Health Conditions: Protocol for an Implementation and Evaluation Study by Ashish Joshi, Surapaneni Krishna Mohan, Apurva Kumar Pandya, Ashoo Grover, Sofia Rani Saggu, Saravanavel Kalpana Revathi, Shruti Sharma

“…ConclusionsThe finding from this research project will aid in the development and implementation of data-driven, evidence-based, and human-centered behavior change interventions using podcasts to address public health challenges among populations living in diverse settings. …”
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Mitochondrial trifunctional protein deficiency caused by a deep intronic deletion leading to aberrant splicing by Thomas Cassini, Sarah Silverstein, Molly Behan, Cynthia J. Tifft, May Christine Malicdan, David R. Adams, Undiagnosed Diseases Network, Sun‐Young Ahn, Debra S. Regier

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De Novo Genome Assembly for an Endangered Lemur Using Portable Nanopore Sequencing in Rural Madagascar by Lindsey Hauff, Noa Elosmie Rasoanaivo, Andriamahery Razafindrakoto, Hajanirina Ravelonjanahary, Patricia C. Wright, Rindra Rakotoarivony, Christina M. Bergey

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Meaningful Engagement as a Cornerstone for Implementing the Key Recommendations to Advance the Sexual and Reproductive Health and Rights of Women Living With HIV Across Policy, Pra... by Zoë Osborne MPH, Muluba Habanyama, Brittany Cameron, Alexandra de Pokomandy MD, MSc, Brenda Gagnier, Elizabeth King MD, Jill Koebel MPH, Mona Loutfy MD, MPH, Carrie Martin BA, BSW, Renée Masching MSW, Manjulaa Narasimhan PhD, Valerie Nicholson, Neora Pick MD, Stephanie Smith, Shelly Tognazzini BA, Wangari Tharao PhD, Angela Kaida PhD

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Feasibility, safety and tolerability of estrogen and/or probiotics for improving vaginal health in Canadian African, Caribbean, and Black women: A pilot phase 1 clinical trial. by Biban Gill, Jocelyn M Wessels, Christina L Hayes, Jenna Ratcliffe, Junic Wokuri, Elizabeth Ball, Gregor Reid, Rupert Kaul, Jesleen Rana, Muna Alkhaifi, Wangari Tharao, Fiona Smaill, Charu Kaushic

“…<h4>Background</h4>A dysbiotic vaginal microbiome (VMB) is associated with clinical conditions such as bacterial vaginosis (BV) and an increased risk of human immunodeficiency virus (HIV-1) infection. Considering the high prevalence of BV among African, Caribbean and Black (ACB) women, we conducted a prospective, randomized, open-label phase 1 clinical trial to determine the feasibility, safety and tolerability of administering low-dose estrogen, probiotics or both in combination to improve vaginal health and decrease HIV-1 susceptibility.…”
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Model Pengambilan Keputusan Pemilihan Bibit Unggul Sapi Bali Menggunakan Metode Weighted Product by Dyna Marisa Khairina, Indra Cahya Pramukti, Heliza Rahmania Hatta, Septya Maharani

“…Decision-making models can be used to help humans, especially cattle ranchers in making decisions. …”
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Designing a model of mutual expectations in the relationship between the person and the organization in governmental organizations and service providers in Isfahan based on the phe... by Abbas Nosouhi, Akbar Etebarian, Mehraban Hadi Peykani

“…One hundred managers and experts of government and service organizations and 100 of their clients were purposefully selected using the pairwise comparison test method and identifying in the quantitative section.Findings: The findings in DEMETEL technique showed that the most impact was related to the factor of capable and knowledgeable client and the most impact was related to the factor of respect for human dignity of employees. Also the findings show that among the components of the organizational questionnaire, the most gaps are in the component of the rule of law and avoidance of illegal methods, and the minor gaps are in the component of participation in client-related organizational systems by using the questionnaire to collect the required information. …”
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Magnitude, risk factors and economic impacts of diabetic emergencies in developing countries: A systematic review. by Halefom Kahsay Haile, Teferi Gedif Fenta

“…As the prevalence of diabetes grows in developing countries, so too does the impact of these costly human and economic complications. Noticeable scarcity of data concerning the magnitude, the cost expenditures as well as well unidentified predictors of these complications made the management more difficult in the resource limited health care settings. …”
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Investigation on inherent angle ventilation control of residential kitchen range hoods by Zhilin Guo, Huixing Li, Guohui Feng, Kailiang Huang, Tengfei Yu

“…The emission of oil fume particles during kitchen cooking processes constitutes a significant factor that impacts indoor air quality and human health. Range hoods, as indispensable ventilation devices in kitchens, play a crucial role in reducing indoor particle concentrations. …”
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CRISPR/Cas9-mediated genomic insertion of functional genes into Lactiplantibacillus plantarum WCFS1 by Kamilla Wiull, Lisa K. Haugen, Vincent G. H. Eijsink, Geir Mathiesen

“…ABSTRACT Lactiplantibacillus plantarum, a natural inhabitant of the human body, is a promising candidate vehicle for vaccine delivery. …”
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Influence of Treadmill Speed and Perturbation Intensity on Selection of Balancing Strategies during Slow Walking Perturbed in the Frontal Plane by Zlatko Matjačić, Matjaž Zadravec, Andrej Olenšek

“…The aim of this study was to investigate strategies that humans use to cope with lateral perturbations during very slow walking. …”
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Contribution à l’étude de la mobilité pollicale des primates actuels. Plaidoyer en faveur de l’importance du rôle de leur pouce by J Norbert Kuhlmann

“…This instability prohibits a powerfull and accurate grip. Only the human has a stable metacarpophalangeal joint. This stability is a critical factor during handling. …”
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Is the EnodePro^® a Valid Tool to Determine the Bar Velocity in the Bench Press and Barbell Back Squat? A Comparative Analysis by Nina Behrmann, Martin Hillebrecht, José Afonso, Konstantin Warneke

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