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23661
Helicobacter mastomyrinus infection induces autoimmune hepatitis in mice
Published 2025-06-01“…This model may serve as a novel animal model for the study of the pathogenesis and potential therapeutic strategies for human AIH.…”
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23662
Performance of Bell Pepper (Capsicum annum) Under Different Grow Bag Media in Lalitpur District, Nepal
Published 2025-01-01“…Promoting rooftop farming using suitable grow bag media is of utmost importance in densely populated cities like Lalitpur to sustain the human race. To assess the productivity and other economic characteristics of bell peppers, an experiment was conducted from Feb 2022 to Jun 2022 in different grow bag media on the premises of Vegetable Crop Development Centre, Khumaltar, Lalitpur. …”
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23663
Association of ambient temperatures with suicide attempts and violence with the future projections under climate change scenarios: a nationwide time-stratified case-crossover study...
Published 2025-02-01“…Abstract Background Both climate change and intentional injuries (suicide attempts and violence) are recognized as crucial factors that affect human health. Previous studies revealed the association between ambient temperatures and deaths due to intentional injuries but mostly about the consequences of severe events. …”
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23664
The association between Planetary Health Diet Index (PHDI) and chronic obstructive pulmonary disease (COPD): the mediating role of dietary inflammatory index (DII)
Published 2025-01-01“…PHDI is a dietary scoring system designed to balance human health and environmental sustainability by promoting increased consumption of plant-based foods and reduced intake of red meat, sugar, and highly processed foods. …”
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23665
Intraperitoneal paclitaxel for patients with primary malignant peritoneal mesothelioma: a phase I/II dose escalation and safety study—INTERACT MESO
Published 2022-06-01“…Through this PAC, 8–16 weekly cycles of intraperitoneal chemotherapy will be administered.Ethics and dissemination The Central Committee on Research Involving Human Subjects (CCMO, The Hague, The Netherlands) and the Medical Research Ethics Committee (METC, Rotterdam, The Netherlands) have granted permission to carry out this study protocol. …”
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23666
Causal relationship of familial hypercholesterolemia with risk of intestinal vascular disorders: A mendelian randomization study
Published 2025-03-01“…This study aims to investigate the cause-and-effect relationship of FH with risk of intestinal vascular diseases in human. Methods: A Mendelian randomization (MR) analysis was performed by extracting summary-level datasets for FH or FH concurrently with ischemic heart disease (IHD) and intestinal vascular diseases from the FinnGen study including 329,115, 316,290 and 350,505 individuals. …”
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23667
Assessments of Antibacterial Effects of Aqueous-Ethanolic Extracts of Sida rhombifolia’s Aerial Part
Published 2018-01-01“…Because of this, searching of new treatment method is important from natural substances to against those infectious diseases in both human and animals’ aspects. Among those plants, Sida rhombifolia has various roles against those infectious diseases through its different phytochemical components. …”
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23668
Identification of the Highly Polymorphic Prion Protein Gene (<i>PRNP</i>) in Frogs <i>(Rana dybowskii</i>)
Published 2025-01-01“…The origin of prion seeds is unclear, especially in non-human hosts, and this identification is pivotal to preventing the spread of prion diseases from host animals. …”
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23669
House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model
Published 2023-01-01“…As guinea pigs exhibit anatomical, physiological, and pharmacological features resembling human airways, including mast cell distribution and mediator release, we evaluated the effect of extracts from two common allergens, house dust mite (HDM) and cat dander (CDE), on histopathological changes and the composition of tryptase- and chymase-positive mast cells in the guinea pig lungs. …”
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23670
Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China
Published 2025-01-01“…Conclusions The clinical manifestations observed in HCWs during and after Omicron infection displayed intricate patterns, shedding new light on the complex interplay between SARS‐CoV‐2 and humans.…”
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23671
Opposing Effects of Omega-3 and Omega-6 Long Chain Polyunsaturated Fatty Acids on the Expression of Lipogenic Genes in Omental and Retroperitoneal Adipose Depots in the Rat
Published 2010-01-01“…This study aimed to determine the effect of varying dietary intake of the major n-3 PUFA in human diets, α-linolenic acid (ALA; 18 : 3n-3), on expression of lipogenic genes in adipose tissue. …”
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23672
Air Quality of Bursa: Temporal and Spatial Evaluation of PM10, PM2.5, NO2 and SO2 Pollutants Using IDW Geostatistical Technique
Published 2025-01-01“…One of the most significant environmental issues is air pollution. Human health is negatively impacted by this issue in addition to the environment. …”
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23673
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling
Published 2025-01-01“…Using a cytokine cocktail containing IL-17A, interferon-gamma and tumour necrosis factor-alpha to produce a psoriasis-like phenotype, a role for ALOX15B in human epidermal keratinocyte inflammation was investigated. siRNA-mediated silencing of ALOX15B increased CCL2 expression and secretion. …”
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23674
Critical signals for grassland desertification prediction in the transition zone between desert and typical steppe in InnerMongolia, China
Published 2025-01-01“…Global climate change and intensifying human activities have driven an accelerated desertification of grasslands in arid and semi-arid regions. …”
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23675
Pollution Characteristics and Source Analysis of Carbonaceous Components in PM2.5 in a Typical Industrial City
Published 2024-03-01“…Abstract Carbonaceous components are important components of fine atmospheric particulate matter (PM2.5) and can affect the local environment, climate, and human health. In this study, online observation data from September 1, 2022, to August 31, 2023, were used to analyze the carbonaceous components, namely, organic carbon (OC) and elemental carbon (EC), in PM2.5 in Jincheng, which is a typical industrial city. …”
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23676
Development of Virus-Like Particles (VLPs) for Hepatitis C Virus genotype 4: a novel approach for vaccine development in Egypt
Published 2025-01-01“…Methods Lentiviral-based vectors were constructed and employed to integrate the full-length sequence of Core, E1, E2, and P7 genes of HCV genotype 4 into the genome of Human Embryonic Kidney cells (HEK293T). Upon the expression, HCV structural proteins can oligomerize and self-assemble into VLPs mimicking the structure of HCV native virus. …”
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23677
Research on the possibility of carrying out convoy driving missions using vehicles with varying degrees of autonomy
Published 2024-12-01“… The objective of this work is to assess the possibility of driving unmanned vehicles in a convoy, depending on the vehicle type (wheeled or tracked, level 0, according to SAE J3016), and the mutual coincidence with a human-controlled vehicle in accordance with the driving scenario adopted. …”
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23678
Current developments in robotic assistance technology for total knee arthroplasty: a comprehensive overview
Published 2025-01-01“…Total knee arthroplasty, also known as TKA, is one of the most effective treatments for osteoarthritis of the knee that has progressed to the end stage. The inevitable human factor in conventional total knee arthroplasty (TKA) frequently results in poor positioning of the prosthesis during the reconstruction of the lower limb's biomechanical axis. …”
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23679
Novel insights into immunopathogenesis and crucial biomarkers between primary open‐angle glaucoma and systemic lupus erythematosus
Published 2024-12-01“…Finally, reverse transcription quantitative real‐time polymerase chain reaction (RT‐qPCR) was performed in human trabecular meshwork stem cells to validate the five identified biomarkers. …”
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23680
Correlation between MDA Level and Chitotriosidase-1 Activity in Seminal Fluid of Iraqi Infertile Males
Published 2024-12-01“…The notable chitinase in humans plays a significant role in the body's immunological response and is linked to inflammation, infection, tissue damage, and remodeling processes. …”
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