Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2 by Shaun Martin, Sarah van Veen, Tine Holemans, Seyma Demirsoy, Chris van den Haute, Veerle Baekelandt, Patrizia Agostinis, Jan Eggermont, Peter Vangheluwe

“…Here, we analyzed stable human SHSY5Y cell lines overexpressing wild-type (WT) or ATP13A2 mutants in which three N-terminal lipid binding sites (LBS1–3) were mutated. …”
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Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon by Kagoué Simeni Luc-Aimé, Yindom Louis-Marie, Loni Ekali Gabriel, Clauvis Kunkeng Yengo, F. Esemu Livo, Nguedia Jules Clement Assob

“…This may be partly due to differences in host immunogenetic factors in highly polymorphic regions of the human genome such as those encoding the killer-cell immunoglobulin-like receptor (KIR) molecules which modulate the activities of natural killer cells. …”
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Tailoring traditional Chinese medicine in cancer therapy by Shuiquan Li, Xi Chen, Hui Shi, Ming Yi, Bing Xiong, Tianye Li

“…The traditional Chinese medicine (TCM), as an embodiment of ancient wisdom, has been validated to regulate the holistic human capacity against both internal and external “evils” in accordance with TCM principles. …”
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Community-based culturally tailored education programmes for black adults with cardiovascular disease, diabetes, hypertension and stroke: a systematic review protocol of primary em... by Hardeep Singh, Michelle LA Nelson, Joseph IV Fulton, Oya Pakkal, Elizabeth M Uleryk

“…The aggregated data will be presented through textual descriptions of programme characteristics and outcomes.Ethics and dissemination This systematic review protocol does not require ethics approval without the inclusion of human participants and will use studies that have previously obtained informed consent. …”
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Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa) by Jinhua He, Geng Zhao, Mingxia Chen, Ximing Ren, Peizhi Zhu, Zhizhong Liu, Jiayi Zhou, Hanwei Chen, Chuqiao Xiao, Xiang-Guang Li

“…The porcine digestive system is physiologically similar to that of humans, making pigs a suitable model for studying DON-induced enterotoxicity. …”
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Characterization of Amino Acid Composition, Nutritional Value, and Taste of Fruits from Different Actinidia arguta Resources by Yanli He, Hongyan Qin, Jinli Wen, Lin Wang, Weiyu Cao, Shutian Fan, Wenpeng Lu, Jiaqi Li, Changyu Li

“…The results of the nutritional value evaluation showed that the Leu of the fruits of the A. arguta resources all conformed to the ideal model proposed by FAO/WHO, and the Leu content of all the resources exceeded the human body’s needs, and it was also found that the first limiting amino acid of the Actinidia argute resources was Ile and the second limiting amino acid was Lys. …”
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Detection and Classification of Teacher-Rated Children’s Activity Levels Using Millimeter-Wave Radar and Machine Learning: A Pilot Study in a Real Primary School Environment by Tianyi Wang, Takuya Sakamoto, Yu Oshima, Itsuki Iwata, Masaya Kato, Haruto Kobayashi, Manabu Wakuta, Masako Myowa, Tokomo Nishimura, Atsushi Senju

“…Traditional assessments of children’s health and behavioral issues primarily rely on subjective evaluation by adult raters, which imposes major costs in time and human resource to the school system. This pilot study investigates the utilization of millimeter-wave radar coupled with machine learning for the objective and semi-automatic detection and classification of children’s activity levels, defined as restlessness, within a real classroom environment. …”
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Renewable energy consumption, institutional quality and life expectancy in EU countries: a cointegration analysis by Anca-Florentina Vatamanu, Mihaela Onofrei, Elena Cigu, Florin Oprea

“…Using panel data from 27 European countries over the period 2000–2020, this study examines the effects of renewable energy consumption on human life expectancy as well as how institutional quality and investment in renewable energy projects might promote better health outcomes. …”
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What motivates West African cocoa farmers to value trees? Taking the 4 W approach to the heart of the field by Marie Ruth Dago, Irié Casimir Zo‐Bi, Isaac Kouamé Konan, Aimé Kouadio Kouassi, Stéphane Guei, Patrick Jagoret, Anny Estelle N'Guessan, Elsa Sanial, Chloé Tankam, Soulemane Traoré, Bruno Hérault

“…The distribution of use values by category shows that the highest values are associated with (i) agronomic uses (such as shade for cocoa trees and soil fertilization), (ii) food for human consumption, (iii) social purposes, and (iv) medicinal uses. …”
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Whole Genome Sequencing Reveals Substantial Genetic Structure and Evidence of Local Adaptation in Alaskan Red King Crab by Carl A. St. John, Laura E. Timm, Kristen M. Gruenthal, Wesley A. Larson

“…A long tradition of responsible fisheries management has sustained these species for generations, but modern threats from climate change, habitat loss, and new fishing technologies threaten their ecosystems and the human communities that depend on them. Among these species, Alaska's most charismatic megafaunal invertebrate, the red king crab, faces all three of these threats and has declined substantially in many parts of its distribution. …”
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Effect of Amelogenin Solution in the Microhardness of Remineralized Enamel and Shear Bond Strength of Orthodontic Brackets by Guilherme Genovez-Júnior, Sandrine Bittencourt Berger, Lucineide Lima dos Santos, Eloisa Aparecida Carlesse Paloco, Murilo Baena Lopes, Débora Fernandes Giuliangeli, Júlia Graciela Monteiro dos Santos, Ricardo Danil Guiraldo

“…Materials and Methods. In total, 24 human premolars were selected and divided into 3 experimental groups (n = 8): SE—sound enamel, DE—demineralized enamel, and TE—demineralized enamel treated with amelogenin solution. …”
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Rare Taxa Are Key Links in Regional Antimicrobial Resistance Profiles in Dusts Across Diverse North American Regions by Paul B. L. George, Florent Rossi, Marc Veillette, Amélia Bélanger Cayouette, Samantha Leclerc, Cindy Dumais, Nathalie Turgeon, Caroline Duchaine

“…Factors positively linked to total numbers of ARGs included human and livestock populations; whereas mean annual precipitation was negatively linked to resistance gene quantities. …”
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A qualitative research on career expectations of civilian nurses in military hospitals (军队医院文职护理人员职业期待的质性研究) by CAI Aini (蔡爱旎), HONG Hanhan (洪涵涵), LU Jiaojiao (卢姣姣), JI Dandan (季丹丹), SHANG Yanjun (尚彦君)

“…Objective To investigate the true career expectations of civilian nurses in military hospitals, so as to provide reference for relevant administrators to formulate plans of human resource management and career development. …”
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Realist evaluation of the impact of the research translation process on health system sustainability: a study protocol by Yvonne Zurynski, Delia Hendrie, Suzanne Robinson, Elizabeth Geelhoed, Abby Mosedale

“…This approach to evaluation of a research translation funding programme may be adapted to similar programmes operating in other settings.Ethics and dissemination Curtin University Human Research Ethics Committee, Western Australia, approved this study (approval number: HRE2020-0464). …”
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Construction and Investigation of MicroRNA-mRNA Regulatory Network of Gastric Cancer with Helicobacter pylori Infection by Ping Yang, Junjie Liu, Tianci Yang, Lei Zhang, Peiyou Gong, Boqing Li, Xiuzhi Zhou

“…Helicobacter pylori (H. pylori) is a common human pathogen, which is closely correlated with gastric cancer (GC). …”
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Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae by Kuang-Yao Chen, Yi-Hsuan Lin, Chien-Ju Cheng, Yi-Hao Huang, Sheng-Yu Lin, Chyi-Liang Chen, Cheng-Hsun Chiu

“…Background: Angiostrongylus cantonensis is a significant foodborne zoonotic parasite that causes severe neuropathological damage and symptoms in humans. Excretory-secretory products (ESPs) play a pivotal role in elucidating host-parasite interactions and can aid in penetrating host defensive barriers in helminths. …”
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Analysis of differentially expressed genes in hypertension and hypertensive cerebral hemorrhage via RNA-sequencing by Hongwu Qi, Min Qiao, Yansong Liu, Weijun Zeng, Lizhao Zhang, Hongjun Guo

“…The RT-qPCR validation results in human subjects and cell models were generally consistent with the sequencing results. …”
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Research on power plant security issues monitoring and fault detection using attention based LSTM model by Shengda Wang, Zeng Dou, Danni Liu, Han Xu, Ji Du

“…Wind power is well distributed around the world, making it suitable to be exploited in human activities for the general welfare of society. …”
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Effects of fiber engraving laser on metallurgical, surface topography, and corrosion properties of AZ80 magnesium-based alloy by Narges Ahmadi, Homam Naffakh-Moosavy, Seyed Mohammad Mahdi Hadavi, Fatemeh Bagheri

“…Magnesium, a lightweight metal similar to natural bone, shows no toxicity and can aid in hard tissue recovery when implanted in the human body. However, its main drawback is its fast degradation rate in medical applications. …”
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Study protocol: an observational study of distress, immune function and persistent pain in HIV by John A Joska, Mark R Hutchinson, Maia Lesosky, Victoria J Madden, Ncumisa Msolo, Luyanduthando Mqadi, Gillian J Bedwell, Jonathan Grant Peter, Romy Parker, Andrew Schrepf, Robert R Edwards

“…The study has been approved by the Human Research Ethics Committee of the University of Cape Town (approval number: 764/2019) and the City of Cape Town (ref: 24699).Trial registration number NCT04757987.…”
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