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22601
Exploring the efficacy of drought tolerant, IAA-producing plant growth-promoting rhizobacteria for sustainable agriculture
Published 2025-12-01“…The growing human population and abiotic stresses pose significant threats to food security, with PGPR favorable as biofertilizers for plant growth and stress relief. …”
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22602
Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter
Published 2025-02-01“…N -Acetylneuraminic acid (Neu5Ac) is a negatively charged nine-carbon amino sugar that is often the peripheral sugar in human cell-surface glycoconjugates. Some bacteria scavenge, import, and metabolize Neu5Ac or redeploy it on their cell surfaces for immune evasion. …”
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22603
Differentiating False Loss of Resistance from True Loss of Resistance While Performing the Epidural Block with the CompuFlo® Epidural Instrument
Published 2019-01-01“…A CompuFlo® epidural instrument has been introduced to measure the pressure of human tissues in real time at the orifice of a needle and has been used as a tool to identify the epidural space. …”
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22604
Mf-net: multi-feature fusion network based on two-stream extraction and multi-scale enhancement for face forgery detection
Published 2024-11-01“…Abstract Due to the increasing sophistication of face forgery techniques, the images generated are becoming more and more realistic and difficult for human eyes to distinguish. These face forgery techniques can cause problems such as fraud and social engineering attacks in facial recognition and identity verification areas. …”
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22605
Enhanced quantitative precipitation estimation through the opportunistic use of Ku TV-SAT links via a dual-channel procedure
Published 2025-01-01“…This technique provides rain measurements at a fine temporal resolution (a few tens of seconds) and with a spatial resolution of a few kilometres, which is a good compromise for human activities such as civil security (watershed monitoring, flash flood), agriculture or transport. …”
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22606
Generation of microdissected DNA probes from metaphase chromosomes when chromosome identification by routine staining is impossible
Published 2020-08-01“…Application of microdissected DNA libraries and DNA probes in numerous and various modern molecular cytogenetic studies showed them as an efficient and reliable tool in the analysis of chromosome reorganization during karyotypic evolution and in the diagnosis of human chromosome pathology. An important advantage of DNA probe generation by metaphase chromosome microdissection followed by sequence-independent polymerase chain reaction in comparison with the method of DNA probe generation using chromosome sorting is the possibility of DNA probe preparation from chromosomes of an individual sample without cell line establishment for the production of a large number of metaphase chromosomes. …”
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22607
Addressing challenges in vector control: a review of current strategies and the imperative for novel tools in India’s combat against vector-borne diseases
Published 2024-07-01“…The promising new vector control tools are insecticide-treated nets with synergist and/or pyrrole chlorfenapyr, alternatives/additions to synthetic pyrethroids like neonicotinoids, clothianidin for indoor residual spray, newer formulations such as Bacillus sphaericus for use in larvicides, attractive toxic sugar baits, especially to curtail outdoor transmission, endectocides like ivermectin for use in animals/humans, insecticidal paints, spatial repellents, insecticide-treated wearables and others. …”
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22608
Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity
Published 2025-01-01“…Additionally, LNP-M effectively delivered DNA-encoded antigens, such as mouse PD-L1 and p53R172H, or monoclonal antibodies targeting mouse PD1 and human p53R282W. This approach inhibited tumor growth or metastasis in several mouse models. …”
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22609
Biological Impact of Exposure to Extremely Fine-Grained Volcanic Ash
Published 2018-01-01“…Detailed studies about the impact of volcanic ash on human health are still lacking. Therefore, the disease of exposed populations is unknown. …”
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22610
A comparative bio-mechanical performance assessment of additively manufactured bone scaffolds using different beta Ti alloys and Gyroid based cellular structure
Published 2025-03-01“…An exponential rise in demand for artificial implants has emphasized the need for novel biomaterials with good biocompatibility and mechanical properties comparable to human cortical and cancellous bone, to mitigate stress shielding and other post implantation challenges. …”
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22611
An open-label study to determine the maximum tolerated dose of oral ESK-440 administered as a single agent in patients with advanced or metastatic solid tumors
Published 2025-03-01“…Tyrosine kinase inhibitors (TKIs) targeting ALK have improved disease outcomes, but resistance mechanisms are common. This first-in-human trial evaluates ESK-440, a dual inhibitor of ALK and focal adhesion kinase, as a novel strategy for cancers with resistance to ALK-targeting TKIs. …”
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22612
Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation
Published 2019-01-01“…To investigate the protective effect of ginsenoside Rg1 on relieving sepsis-induced lung inflammation and injury in vivo and in vitro. Methods. Cultured human pulmonary epithelial cell line A549 was challenged with LPS to induce cell injury, and CLP mouse model was generated to mimic clinical condition of systemic sepsis. …”
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22613
Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome
Published 2022-01-01“…The murine RNA-sequencing data were validated with mouse and human MFS aortic tissue, demonstrating elevated Notch3 activation in MFS. …”
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22614
Spray-Induced Gene Silencing (SIGS): Nanocarrier-Mediated dsRNA Delivery Improves RNAi Efficiency in the Management of Lettuce Gray Mold Caused by <i>Botrytis cinerea</i>
Published 2025-01-01“…The management of gray mold disease is still mainly based on the use of chemicals, which could have harmful effects not only due to impacts on the environment and human health, but also because they favor the development of fungicide-resistant strains. …”
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22615
Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance
Published 2025-01-01“…The visually-based immunochromatographic test (ICT) described herein allows for quick detection and quantification of IgG and IgM FH-FHAA complexes in human EDTA-plasma or serum. This ICT offers improved detection of FHAAs compared to ELISA as demonstrated by cases where the ICT identifies FH-FHAA complexes in samples that tested negative with the free FHAA ELISA. …”
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22616
Fatal intoxication after oral ingestion of amphetamine: Two case reports
Published 2025-06-01“…The toxicity of the amphetamine by-products on the human body remains unclear and is subject of further studies.…”
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22617
Genetic Analysis of Cytokine Promoters in Nonhuman Primates: Implications for Th1/Th2 Profile Characteristics and SIV Disease Pathogenesis
Published 2004-01-01“…The shift from a predominant synthesis of prototype Th1 cytokines to Th2 or Th0 type of cytokines by antigen activated PBMC's from HIV infected humans and SIV infected disease susceptible rhesus macaques (RM) has been shown to be associated with disease progression. …”
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22618
The Role of Antioxidant Activity of Chitosan-Pinus merkusii Extract Nanoparticle in against Lead Acetate-Induced Toxicity in Rat Pancreas
Published 2019-01-01“…Lead is one of the heavy metals with oxidative stress that causes toxicity in human and animals. The aim of this study was to evaluate the antioxidant activity of Chitosan-Pinus merkusii extract nanoparticle on lead acetate-induced toxicity in rat pancreas. …”
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22619
Comprehensive analysis of H3K27me3 LOCKs under different DNA methylation contexts reveal epigenetic redistribution in tumorigenesis
Published 2025-01-01“…Result In this study, we identify and categorize H3K27me3 LOCKs in 109 normal human samples, distinguishing between long and short LOCKs. …”
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22620
Distribution and Conservation of Ephedra rhytidosperma
Published 2025-01-01“…ABSTRACT With global warming and increasingly intensified human activities, numerous species are on the verge of extinction, ca. 28% of living species are threatened globally, although conservation of endangered species has received worldwide attention. …”
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