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22381
Equipping our public health nutrition workforce to promote planetary health: a case example of tertiary education co-designed with students
Published 2025-01-01“…Students’ descriptions of what planetary health means to them were focused on humans’ role in protecting and preserving the ecosystem, the responsible and sustainable use of natural resources and a need to sustain a healthy life for future generations. …”
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22382
Carboxymethyl Hyaluronan-Stabilized Nanoparticles for Anticancer Drug Delivery
Published 2015-01-01“…These studies tested the ability of CMHA to stabilize the formation of calcium phosphate nanoparticles and evaluated their potential to target therapy resistant, CD44+/CD24−/low human breast cancer cells (BT-474EMT). CMHA stabilized particles (nCaPCMHA) were loaded with the chemotherapy drug cis-diamminedichloroplatinum(II) (CDDP) to form nCaPCMHACDDP. …”
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22383
An electrolyte-gated transistor for the monitoring of a CRISPR/Cas activity
Published 2025-05-01“…Detection of Ribonucleic acids (RNA) is a critical step in the identification of viral or bacterial infections in humans and animals. Reverse transcriptase-polymerase chain reaction (RT-PCR) remains the gold standard, but clustered regularly interspaced short palindromic repeats linked to a Cas endoribonuclease particle (CRISPR/Cas) have recently revolutionized the recognition step of two RNAs, i.e. the CRISPR-RNA (crRNA) and the target, providing a much better selectivity compared to the naked hybridization on which RT-PCR is based. …”
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22384
Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity
Published 2018-09-01“…During conducting a first-in-human trial for a new molecular entity, we were able to determine the mechanism of dichotomized variability in plasma drug concentrations, which appeared closely related to adverse drug reactions (ADRs) through integrated omics analysis. …”
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22385
Life Cycle Assessment of Methanol Production from Municipal Solid Waste: Environmental Comparison with Landfilling and Incineration
Published 2025-01-01“…To answer this, this study evaluates the environmental performance of MSW-to-methanol technologies using life cycle assessment (LCA), focusing on key indicators such as global warming potential, resource depletion, and impacts on human health and ecosystem quality. The results reveal that methanol production from MSW significantly reduces global warming potential (GWP) by 87% compared to landfilling and 56% compared to incineration. …”
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22386
Infiltration and subtype analysis of CD3 + CD20 + T cells in lung cancer
Published 2025-01-01“…Abstract Background CD3 + CD20 + T cells (TB cells) are a subset of lymphocytes in the human body that are associated with inflammation. …”
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22387
Liquid chromatography-high resolution mass spectrometry based analysis of persistent mobile organic compounds in aqueous samples: Method development and optimization
Published 2025-03-01“…Persistent Mobile Organic Compounds (PMOCs) represent a critical threat to water resources due to their high solubility, resistance to degradation, and potential toxicity, posing risks to human health and ecosystems. Their detection and analysis are particularly challenging, necessitating advanced analytical techniques to support regulatory measures and ensure safe drinking water. …”
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22388
A comprehensive analysis of the epidemiological and genomic characteristics of global Serratia Marcescens
Published 2025-01-01“…Results: The study analysed genomes from 33 countries, with major contributions from the USA (27.8%), UK (15.3%), Italy (14.7%), and Japan (10.7%). Human clinical samples accounted for 73.5% of the isolates, primarily from blood (44.8%) and sputum (19.3%). …”
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22389
The impact of the Lesotho health reform in the re-structuring of the village health workers program
Published 2025-01-01“…Abstract Background Community Health Workers locally known as Village Health Workers (VHW) in Lesotho are key members of the primary health workforce, and has been playing a significant role in building primary health systems in many countries and they can fill significant gaps in human resources as low and middle income countries work towards universal health coverage in the era of Sustainable Development Goals (SDGs). …”
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22390
The Role of Artificial Lakes Located in Forests in the Context of Small Retention, Biodiversity and Climatic Changes—Evidence From Southern Poland
Published 2025-01-01“…The model of plant associations showed the occurrence of 24 species of plants within nine plant assemblages in the Phragmitetea and Potametea classes of associations (Biocenotic index 1.007–1.692). Despite human activities, lake condition, as assessed by the ESMI index or the biocenotic diversity indices, is good (0.416–0.648). …”
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22391
Examining Indonesian College Students’ Behavioral Intention of Using Moodle App for E-Learning Platform
Published 2024-08-01“…However, the technology readiness and acceptance of the human resource to this shift towards distance education via Learning Management System (LMS) remained in question. …”
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22392
An extensive review on implantable antennas for biomedical applications: Health considerations, geometries, fabrication techniques, and challenges
Published 2025-01-01“…Meeting these stringent standards is essential to ensure that IMDs operate safely and effectively within the human body over extended periods. By providing an in-depth review of state-of-the-art solutions and identifying emerging trends, this paper serves as an invaluable resource for researchers, engineers, and medical practitioners involved in the design and deployment of implantable medical devices. …”
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22393
One Earth-One Health (OE-OH): Antibacterial Effects of Plant Flavonoids in Combination with Clinical Antibiotics with Various Mechanisms
Published 2024-12-01“…<b>Background/Objectives:</b> Antimicrobial resistance (AMR) poses a significant threat to human health, and combination therapy has proven effective in combating it. …”
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22394
Chronic Inflammation May Enhance Leiomyoma Development by the Involvement of Progenitor Cells
Published 2018-01-01“…The aim of this work was to understand if progenitor cells sustain a chronic inflammatory microenvironment that enhances leiomyoma development. Cells from 12 human leiomyoma and 12 normal myometrium samples of the same patients were in vitro isolated and exhaustively characterized (morphology, proliferation, cytofluorometry, differentiation, RT-PCR, immunofluorescence, immunohistochemistry, and Western blotting assays). …”
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22395
Application and Evaluation of [Tc]-Labeled Peptide Nucleic Acid Targeting in Breast Cancer Imaging
Published 2020-06-01“…Both antisense PNA (anti-PNA, fully complementary bound to human mature miR-155 , referred to as “anti-PNA-155”) and mismatched PNA (referred to as “mis-PNA”) single strands containing 23-mer were synthesized. …”
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22396
Concordance of Australian state and territory government guidelines for classifying the healthiness of foods in public settings
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22397
Filterable PM2.5, Metallic Elements, and Organic Carbon Emissions from the Exhausts of Diesel Vehicles
Published 2020-05-01“…Abstract Urban air pollution in the form of fine particulate matter (PM2.5) poses a substantial health threat to humans via inhalation. To assess the risks from this pollutant, we characterized and quantified the PM2.5 exhausted by 15 diesel vehicles ranging from 28,306 to 883,374 km (an average of 525,854 km) in total mileage and varying in manufacturer and model year (1988–2005). …”
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22398
Spatiotemporal range dynamics and conservation optimization for endangered medicinal plants in the Himalaya
Published 2025-01-01“…The Himalaya, a global biodiversity hotspot, harbors one of the richest medicinal plant communities, which are economically significant and contribute to human well-being through their health benefits. However, our understanding of species distribution across space and time under climate change scenarios, as well as effective conservation planning for these medicinal plants in the Himalaya, remains limited. …”
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22399
Identifying Zoonotic Parasites in Domiciled and Non‐Domiciled Dogs (Canis lupus familiaris) Within an Urban Zone of the Eastern State of Mexico
Published 2024-11-01“…Interactions among non‐domiciled dogs, domiciled dogs and humans heighten the risk of transmission. Implementing prevention, control and awareness strategies is crucial to reduce the spread of these parasites.…”
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22400
Succinate Supplement Elicited “Pseudohypoxia” Condition to Promote Proliferation, Migration, and Osteogenesis of Periodontal Ligament Cells
Published 2020-01-01“…The purpose of the present study was to explore whether a supplement of succinate, a natural metabolite of the tricarboxylic acid (TCA) cycle, can mimic hypoxia condition to promote human periodontal ligament cells (hPDLCs). Culturing hPDLCs in hypoxia condition promoted cell proliferation, migration, and osteogenic differentiation; moreover, hypoxia shifted cell metabolism from oxidative phosphorylation to glycolysis with accumulation of succinate in the cytosol and its release into culture supernatants. …”
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