Lessons learnt from measures taken to prevent rabies introduction and spread into a long rabies free territory (case study of the Irkutsk Oblast) by I. V. Meltsov, A. M. Ablov, E. N. Shkolnikova, M. E. Koplik, P. A. Minchenko, T. V. Desyatova, I. D. Zarva, A. D. Botvinkin, A. Ye. Metlin

“…Retrospective study of archive and previously published reports on human and animal rabies cases in the Irkutsk Oblast starting from 1954 was performed. …”
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Integrative analysis of Ewing’s sarcoma reveals that the MIF-CD74 axis is a target for immunotherapy by Fangzhou He, Jiuhui Xu, Fanwei Zeng, Boyang Wang, Yi Yang, Jie Xu, Xin Sun, Tingting Ren, Xiaodong Tang

“…Methods Since novel immunotherapies may address this need, we performed an integrative analysis involving single-cell RNA sequencing, cell function experiments, and humanized models to dissect the immunoregulatory interactions in EwS and identify strategies for optimizing immunotherapeutic efficacy. …”
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Chronic GIPR agonism results in pancreatic islet GIPR functional desensitisation by Iona Davies, Alice E. Adriaenssens, William R. Scott, David Carling, Kevin G. Murphy, James S. Minnion, Stephen R. Bloom, Ben Jones, Tricia M-M. Tan

“…Understanding whether pancreatic GIPR desensitisation affects the long-term benefits of GIPR agonists in humans is vital to design effective metabolic pharmacotherapies.…”
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Cryopreservation of epididymal semen of domestic cat by S. Ya. Amstislavsky, E. Yu. Brusentsev, V. I. Mokrousova, E. A. Kizilova, V. V. Kozhevnikova, V. A. Naprimerov, I. N. Rozhkova

“…Taken together these results suggest that both CPAs are suitable for the purpose of domestic cat semen freezing and cryopreservation, although CPF was designed for Canidae semen cryopreservation and SF was developed for human semen freezing and so far was used exclusively in reproductive medicine. …”
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Radioprotective effects of polysaccharides from Poria cocos peels against 60Co-γ induced oxidative damage in vitro and in vivo by Keke Suo, Chaoqiang Zheng, Zhipeng Li, Limin Hao, Jiaqing Zhu, Changcheng Zhao, Yanling Shi, Juanjuan Yi, Jike Lu

“…Ionizing radiation (IR) can produce superfluous reactive oxygen species (ROS) and induce oxidative damage to human health. In view of the shortcomings of chemosynthetic radioprotectors, natural radioprotectors have garnered attention due to their effectiveness, safety, and suitability for long-term use. …”
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Diagnosis and presenting features of autoimmune hepatitis at a central referral hospital in South Africa by Y Maharaj, V G Naidoo

“…Similarly, few studies have focused on the relationship between AIH and Human-Immunodeficiency Virus (HIV) infection. Aim We aim to describe the presenting features of AIH from a single referral centre in a Sub-Sahara African setting. …”
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Oncogenic RIT1 mutations confer ferroptosis vulnerability in lung adenocarcinoma by Ruilan Ma, Dian Yang, Peng Wang, Ziyi Zhang, Xuehong Zhang, Jialiang Song, Han Liu, Shuyan Liu, Yingqiu Zhang, Lijuan Zou

“…Abstract Members from the RAS GTPase superfamily have been closely implicated in the tumorigenesis of various human cancers. Recent sequencing analysis of lung adenocarcinoma has revealed the prevalence of alterations in the RIT1 gene that is a close RAS paralog. …”
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Iron deficiency anaemia and its associated risk factors among lactating mothers in Ghana by Mensah K, Abbam G, Gadzeto FF, Marfo L, Daud S, Kuntah S, Bani SB, Dzamesi HK, Apodola FA, Badu A, Chukwurah FE

“…ackground: Anaemia is one of the most common conditions affecting human physiology. Iron deficiency, with or without anaemia, reduces the working capacity of individuals and the entire population. …”
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Benefits of Immobilized Bacteria in Bioremediation of Sites Contaminated with Toxic Organic Compounds by Emanuel Gheorghita Armanu, Simone Bertoldi, Łukasz Chrzanowski, Irina Volf, Hermann J. Heipieper, Christian Eberlein

“…It focuses on the following four key areas: (i) the types of organic pollutants impacting environmental and human health, (ii) the bacterial strains used in bioremediation processes, (iii) the types and benefits of immobilization, and (iv) the immobilization of bacterial cells on various carriers for targeted pollutant degradation.…”
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Association between Consumption of Fluoroquinolones and Carbapenems and Their Resistance Rates in Pseudomonas aeruginosa in Argentina by Silvia Boni, Gustavo H. Marin, Laura Campaña, Lupe Marin, Soledad Risso-Patrón, Gina Marin, Fernanda Gabriel, Alejandra Corso, Valeria Garay, Manuel Limeres

“…Irrational use of antimicrobials (ATMs) triggers microbial resistance (AMR) which has severe consequences for human health. ATM consumption varies among countries and within each territory. …”
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Study on Seroprevalence and Leptospiral Antibody Distribution Among Livestock Breeders and Farmers in Golestan Province by Malihe Naderi, Vahideh Hamidi Sofiani, Reza Hoseinpour, Amir Mohammad Alborzi, Seyed Amir Soltani

“…ABSTRACT Background The high prevalence of leptospirosis in humans is of great public health concern, particularly in tropical and subtropical regions. …”
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Thymus ad astra, or spaceflight-induced thymic involution by Wataru Muramatsu, Wataru Muramatsu, Maria Maryanovich, Maria Maryanovich, Maria Maryanovich, Taishin Akiyama, Taishin Akiyama, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis

“…Understanding these dynamics will not only enhance the safety of human space missions but also provide critical insights into thymus biology under extreme conditions.…”
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YKL-40 as a Novel Factor Associated with Inflammation and Catabolic Mechanisms in Osteoarthritic Joints by Tuija Väänänen, Anna Koskinen, Erja-Leena Paukkeri, Mari Hämäläinen, Teemu Moilanen, Eeva Moilanen, Katriina Vuolteenaho

“…Moreover, IL-6 and IL-17 enhanced YKL-40 production in human primary chondrocyte cultures. The present study introduces YKL-40 as a cartilage-derived factor associated with mediators of inflammation and cartilage destruction involved in the pathogenesis of OA.…”
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The mirror preference test: A reverse translational approach to study anomalous subjective experience in rats by Daria Chestnykh, Liubov S. Kalinichenko, Stephan von Hörsten, Johannes Kornhuber, Christian P. Müller

“…Symptoms related to the misinterpretation of reality are crucial for diagnosis but pose challenges for preclinical research. In humans, a Mirror-Gazing test is used to examine abnormal self-experience and to predict the risk of schizophrenia. …”
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Complementary Non‐invasive Fish Monitoring Distinguishes Depth‐Dependent Fish Communities by Ewan Burns, Vijini Mallawaarachchi, Thomas M. Clarke, Belinda Martin, Joseph D. DiBattista, Jamie Hicks, Danny Brock, Elizabeth A. Dinsdale, Charlie Huveneers, Michael P. Doane

“…ABSTRACT Human activities are increasingly affecting marine environments, with fish communities serving as critical indicators of ecosystem health. …”
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The Prognostic Significance of TRs in Hepatocellular Carcinoma: Insights from TCGA and GEO Databases by Hao Zhou, Weijie Wang, Ruopeng Liang, Rongtao Zhu, Jiahui Cao, Chenguang Sun, Yuling Sun

“…Background: Reduced expression of thyroid hormone receptors (TRs) has been observed in various human malignancies, though its predictive value in hepatocellular carcinoma (HCC) remains uncertain. …”
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Isolation of Helicobacter pylori from Gastric Biopsy of Dyspeptic Patients in Ghana and In Vitro Preliminary Assessment of the Effect of Dissotis rotundifolia Extract on Its Growth by Michael Buenor Adinortey, Charles Ansah, Cynthia Ayefoumi Adinortey, Ansumana Sandy Bockarie, Martin Tangnaa Morna, Damian H. Amewowor

“…Helicobacter pylori (H. pylori) is a gram-negative bacterium that colonizes the human stomach. Infection with this microaerophilic bacterium causes gastric and duodenal ulcer. …”
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Antimicrobial Activity of Aspergillus sp. from the Amazon Biome: Isolation of Kojic Acid by Josy Caldas Rodrigues, Weison Lima da Silva, David Ribeiro da Silva, Carolina Rabelo Maia, Clarice Virginia Santos Goiabeira, Haile Dean Figueiredo Chagas, Gigliola Mayara Ayres D’Elia, Gleica Soyan Barbosa Alves, Viviane Zahner, Cecilia Veronica Nunez, Ormezinda Celeste Cristo Fernandes

“…The elucidated molecule was evaluated for cytotoxicity against the human fibroblast strain (MRC5). The extract presented inhibitory activity against both Gram-positive and negative bacteria, with the range of inhibition halos from 5.3 to 14 mm in diameter and an MIC ranging from 500 to 15.6 μg/mL. …”
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Vision-Based Underwater Docking Guidance and Positioning: Enhancing Detection with YOLO-D by Tian Ni, Can Sima, Wenzhong Zhang, Junlin Wang, Jia Guo, Lindan Zhang

“…This study proposed a vision-based underwater vertical docking guidance and positioning method to address docking control challenges for human-operated vehicles (HOVs) and unmanned underwater vehicles (UUVs) under complex underwater visual conditions. …”
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Evaluation of a compressed air foam system to clean quail rearing facilities by Jill Wright Skrobarczyk, David James Caldwell, Kenneth Scott McKenzie, Ashley Charles Blankenburg, James Allen Byrd, Morgan Brian Farnell

“…This is especially important in cases of salmonellosis where there is a risk of disease transmission to humans. Compressed air foam systems (CAFS) may serve as an alternative carrier for foaming agents to clean and sanitize agricultural surfaces following an outbreak. …”
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