Therapeutic efficacy of LysGH15 against necrotising pneumonia caused by Staphylococcus aureus in a rabbit model by Bowei Zhang, Liran Song, Yongran Wang, Meimei Zhang, Chong Chen, Hui Ning, Li Wang, Cao Qiu, Xinwu Wang, Changjiang Sun, Xin Feng, Wenyu Han, Wenyu Han, Bin Wang, Yalu Ji, Jingmin Gu, Jingmin Gu

“…IntroductionStaphylococcus aureus (S. aureus) is one of the most important zoonotic pathogens and can be transmitted to humans through the meat diet routes, causing necrotising pneumonia.MethodsThis study investigated the therapeutic effect of bacteriophage lysin LysGH15 on necrotising pneumonia in rabbit model caused by S. aureus.ResultsIn the in vitro experiments, 50 μg/mL LysGH15 not only significantly reduced the viable count (approximately 3.24 × 106 CFU/g) of chicken meat stored at 4°C for 48 h but also effectively reduced the viable count of chicken meat thawed at 4°C and 30°C, with reductions of approximately 1.42 × 106 CFU/g and 2.78 × 106 CFU/g, respectively. …”
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Effect of Double Masking with Silk or Cotton Over-masks on the Source Control Capabilities of a Surgical Mask by Adam F. Parlin, Mikhail Yermakov, Samuel M. Stratton, Susan R. Reutman, Theresa M. Culley, Patrick A. Guerra, Sergey A. Grinshpun

“…Finally, an additional study with five human subjects revealed no significant differences in perceived comfort (measured by proxies such as relative humidity, temperature, and CO2 level inside the mask) between single masking and double masking, as well as between double masking with either a silk or cotton over-mask.…”
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Exploring the Anticancer Potential of MonoHER (7-Mono-O-(β-Hydroxyethyl)-Rutoside): Mitochondrial-Dependent Apoptosis in HepG2 Cells by Chujie Li, Yue Wang, Jian Liang, Guido R. M. M. Haenen, Yonger Chen, Zhengwen Li, Ming Zhang, Ludwig J. Dubois

“…Conclusion: MonoHER can inhibit cell growth and induce apoptosis especially in HepG2 human liver cancer cells by triggering the mitochondrial signal transduction pathway, leading to the release of cytochrome C in the cytoplasm and the subsequent activation of caspase-9 and caspase-3. …”
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Assessing the role of selenium in Minamata disease through reanalysis of historical samples by Mineshi Sakamoto, Masumi Marumoto, Koichi Haraguchi, Takashi Toyama, Yoshiro Saito, Steven J. Balogh, Chiharu Tohyama, Masaaki Nakamura

“…Minamata disease, a severe neurological disorder identified in Japan in 1956, results from methylmercury (MeHg) intoxication in humans due to environmental contamination. Before MeHg was recognized as the cause, selenium (Se) was suspected of being the potential cause owing to elevated Se levels in patients’ organs. …”
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Serum Levels of IL-1β, IL-6, TGF-β, and MMP-9 in Patients Undergoing Carotid Artery Stenting and Regulation of MMP-9 in a New In Vitro Model of THP-1 Cells Activated by Stenting by Rongrong Zhang, Fan Jiang, Cindy Si Chen, Tianzhu Wang, Jinzhou Feng, Tao Tao, Xinyue Qin

“…Second, we established a new in vitro model, where THP-1 monocytes were treated with the supernatants of human umbilical vein endothelial cells (HUVECs) that were scratched by pipette tips, which mimics monocytes activated by mechanical injury of stenting. …”
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First Report on Association of Hyperuricemia with Type 2 Diabetes in a Vietnamese Population by Tran Quang Binh, Pham Tran Phuong, Nguyen Thanh Chung, Bui Thi Nhung, Do Dinh Tung, Tran Quang Thuyen, Duong Tuan Linh, Bui Thi Thuy Nga, Nguyen Anh Ngoc, Le Danh Tuyen

“…Uric acid is a powerful free-radical scavenger in humans, but hyperuricemia may induce insulin resistance and beta-cell dysfunction. …”
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Adsorption of iron by using hybrid Akar Putra and commercialized chicken eggshells as bio-sorbents from aqueous solution by H.M. Nasir, A. Azmi, A.Z. Aris, S.M. Praveena

“…Heavy metal contamination in the environment could cause harmful effects both to human health and aquatic life. Numerous remediation methods had been developed to encounter with the contamination problem prior to degrade, decrease and to purify the contaminated water at minimal concentration as low as possible. …”
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CD4+CD25highCD127low/−FoxP3+ Regulatory T Cell Subpopulations in the Bone Marrow and Peripheral Blood of Children with ALL: Brief Report by M. Niedźwiecki, O. Budziło, M. Zieliński, E. Adamkiewicz-Drożyńska, L. Maciejka-Kembłowska, T. Szczepański, P. Trzonkowski

“…CD4+CD25highCD127low/−FoxP3+ regulatory T cells (Tregs) are currently under extensive investigation in childhood acute lymphoblastic leukemia (ALL) and in other human cancers. Usually, Treg cells maintain the immune cell homeostasis. …”
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The Use of Digital Microscopy to Compare the Thicknesses of Normal Corneas and Ex Vivo Rejected Corneal Grafts with a Focus on the Descemet’s Membrane by Taíse Tognon, Sabrina Bergeron, Christina Mastromonaco, Kleyton Barella, Adriano Pasqualotti, Laura Nunez, Francisco Murta, Luciene Barbosa de Sousa, Mauro Campos, Miguel Noel Nascentes Burnier

“…Histopathological sections of 25 normal human corneas and 40 FGRs were fully digitalized and examined. …”
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Antimildew Treatment and Control Effect of Citral on Bamboo by Jingjing Zhang, Chungui Du, Rui Peng, Ailian Hu, Qi Li, Chunlin Liu, Yingying Shan, Shiqin Chen, Wenxiu Yin

“…Presently, chemical agents remain the main antimildew agents for bamboo, which has a certain negative impact on the environment and human health. Therefore, it is urgent to develop new environment-friendly antimildew agents for bamboo. …”
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Impact of Strontium and Krypton Release from Ghana’s MNSR following a Conjectural Accident Scenario by S. A. Birikorang, R. G. Abrefah, H. K. Obeng, K. Gyamfi

“…No adverse effect was experienced with respect to human health and the environment.…”
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Development of a novel encystment medium: Enhancing diagnostic potential of Acanthamoeba spp. by Julalak Chuprom, Suthinee Sangkanu, Watcharapong Mitsuwan, Rachasak Boonhok, Alok K. Paul, Sonia M. Rodrigues Oliveira, Maria L. Pereira, Tajudeen O. Jimoh, Mohammed Rahmatullah, Polrat Wilairatana, Christophe Wiart, Ajoy K. Verma, Veeranoot Nissapatorn

“…Background and Aim: Acanthamoeba spp. are pathogenic microorganisms linked to severe infections in humans and animals, requiring a deeper understanding of their encystation process for effective diagnostics and research. …”
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Interleukin 10 Plays an Important Role in Neonatal Rats with Hypoxic-Ischemia Associated with B-Cell Lymphoma 2 and Endoplasmic Reticulum Protein 29 by Xue Bai, Liu-Lin Xiong, Chang-Le Fang, Hao-Li Zhou, Lu-Lu Xue, Yue Hu, Qing-Jie Xia, Jia Liu, Jun-Yan Zhang, Ting-Hua Wang, Si-Jin Yang

“…Interleukin 10 (IL-10) is a synthetic inhibitor of human cytokines with immunomodulatory and anti-inflammatory effects. …”
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Exploring the nexus between economic growth and economic performance in Nepal by Yadav Mani Upadhyaya, Khom Raj Kharel, Suman Kharel, Basu Dev Lamichhane

“…This study found that short-term causality running from lagged GDP, gross capital formation (GCF), exports, human development index (HDI), and employment ratio influence immediate GDP growth. …”
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Exploring Synergies: Greenhouse Gas Dynamics, Soil Mechanisms, and Forest Ecosystems for Climate Resilience and Sustainable Environmental Stewardship by Ihsan Muhammad, Xinyu Luo, Imran Khan, Abdullah Ahmed Al‐Ghamdi, Mohamed Soliman Elshikh, Weijun Shen

“…This research provides valuable insights for promoting a sustainable balance between human activities and the vital role of forests in maintaining a healthy environment.…”
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Role of the Kaiso gene in the development of inflammation in Mucin-2 defcient mice by E. A. Litvinova, K. M. Achasova, M. A. Borisova, S. V. Zhenilo, E. B. Prokhortchouk, E. N. Kozhevnikova

“…We have shown that mice with impaired intestinal barrier function that develop processes similar to human IBD also develop inflammatory responses, such as increased expression of Il1, Tnf and Il17a genes. …”
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HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content by Dedipya Yelamanchili, Baiba K. Gillard, Antonio M. Gotto, Jr., Miguel Caínzos Achirica, Khurram Nasir, Alan T. Remaley, Corina Rosales, Henry J. Pownall

“…Here we show that plasma HDL-FC content varies 2-fold among normolipidemic human subjects and linearly correlates with low-density lipoprotein (LDL)-FC content. …”
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Finger roots (Uvaria chemea) and African greenheart (Cylicodiscus gabunensis): Alternative potent therapy to sildenafil in erectile dysfunction by Etukudo Okon Jimmy, Grace Edet Bassey, Abijah Ekwere, Udoh Idorenyin Umoh, Adeyemi Fatai Odetayo, Udoh Nsikan Malachy

“…Further investigations are necessary to elucidate the underlying mechanisms of action, determine optimal dosages, and evaluate the long-term safety profiles of these herbal extracts for potential human applications.…”
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Perception, Trust, and Motivation in Consumer Behavior for Organic Food Acquisition: An Exploratory Study by Elena Moroșan, Violeta Popovici, Ioana Andreea Popescu, Adriana Daraban, Oana Karampelas, Liviu Marian Matac, Monica Licu, Andreea Rusu, Larisa-Marina-Elisabeth Chirigiu, Sinziana Opriţescu, Elena Iuliana Ionita, Alina Saulean, Maria Nitescu

“…(1) Background: A sustainable healthy diet assures human well-being in all life stages, protects environmental resources, and preserves biodiversity. …”
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Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade by Junjie Li, Yuandong Luo, Quanlan Fu, Shuxian Tang, Pingping Zhang, Ian H. Frazer, Xiaosong Liu, Tianfang Wang, Guoying Ni

“…These results indicate that F1/F3 may be effective to improve the efficacy of ICB and therapeutic vaccine-based immunotherapy for human epithelial cancers and warrants consideration for clinical trials.…”
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