Evaluating the Mechanisms of Improved Glucose Homeostasis after Bariatric Surgery in Ossabaw Miniature Swine by Jonathan G. Sham, Vlad V. Simianu, Andrew S. Wright, Skye D. Stewart, Mouhamad Alloosh, Michael Sturek, David E. Cummings, David R. Flum

“…Conclusions. Similar to humans, Ossabaw swine exhibit both obesity-dependent and obesity-independent IR. …”
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Evaluation of post-earthquake fractures according to anatomical body parts: A retrospective study by Muhammed Furkan Arpaci, Ferhat Tas, Gokce Bagci Uzun, Mehmet Akcicek, Feyza Inceoglu, Mine Argali Deniz, Emre Demirel, Hidir Pekmez

“…Bone fractures that occur in earthquakes threaten human life. The study aims to localize the fractures in earthquake victims according to anatomical regions in the earthquake centered in Kahramanmaraş 2023. …”
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Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease by Hui Xu, Anakha Ajayan, Ralf Langen, Jeannie Chen

“…We investigated whether these defects extend to the zQ175KI mouse model which is thought to be more representative of the human condition because it was engineered to contain the extended CAG repeat within the endogenous HTT locus. …”
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Pain in the Prehospital Setting in Rwanda: Results of a Mixed-Methods Quality Improvement Project by A. Rosenberg, E. Uwitonze, M. Dworkin, J. P. D. Guidry, T. Cyuzuzo, D. Banerjee, K. McIntyre, K. Carlyle, J. M. Uwitonze, I. Kabagema, T. Dushime, S. Jayaraman

“…Introduction. Pain is a universal human experience tied to an individual’s health but difficult to understand. …”
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High-performance UWB Vivaldi antenna on FR4: A cost-effective solution for wearable technologies by Sahar Saleh, Tale Saeidi, Nick Timmons, Bader Alali, Faroq Razzaz, Ayman A. Althuwayb

“…The antenna's suitability for wearable applications was validated through testing on flat and curved human phantoms made of skin, fat, and muscle, showing low Specific Absorption Rate (SAR) values across the UWB spectrum, confirming its safety for body-centric use. …”
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Ferroptosis triggers mitochondrial fragmentation via Drp1 activation by Lohans Pedrera, Laura Prieto Clemente, Alina Dahlhaus, Sara Lotfipour Nasudivar, Sofya Tishina, Daniel Olmo González, Jenny Stroh, Fatma Isil Yapici, Randhwaj Pratap Singh, Nils Grotehans, Thomas Langer, Ana J. García-Sáez, Silvia von Karstedt

“…Abstract Constitutive mitochondrial dynamics ensure quality control and metabolic fitness of cells, and their dysregulation has been implicated in various human diseases. The large GTPase Dynamin-related protein 1 (Drp1) is intimately involved in mediating constitutive mitochondrial fission and has been implicated in mitochondrial cell death pathways. …”
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Association between herpes simplex virus infection and Alzheimer’s disease biomarkers: analysis within the MAPT trial by Morgane Linard, Isabelle Garrigue, Bruno Vellas, Nicola Coley, Henrik Zetterberg, Kaj Blennow, Nicholas James Ashton, Pierre Payoux, Anne-Sophie Salabert, Jean-François Dartigues, Joachim Mazere, Sandrine Andrieu, Catherine Helmer

“…Here, we studied the association between HSV-1 and Alzheimer’s disease biomarkers in humans. Our sample included 182 participants at risk of cognitive decline from the Multidomain Alzheimer Preventive Trial who had HSV-1 plasma serology and an amyloid PET scan. …”
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Multiple Dental Inclusion in Monozygotic Twins with Congenital Visual Impairment by G. Galluccio, A. Impellizzeri, A. A. De Stefano, E. Serritella, E. Guercio Monaco

“…Finally, the possibility that alterations in the eruptive pattern of the dental elements may be associated with other congenital problems broadens the range of investigations related to the possible aetiological causes of the inclusions in humans.…”
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Assessment of Wettability and Contact Angle of Bonding Agent with Enamel Surface Etched by Five Commercially Available Etchants: An In Vitro Study by Deepika Katyal, Aravind Kumar Subramanian, Adith Venugopal, Anand Marya

“…Materials and Methods. Twenty-five human maxillary and mandibular central incisors and premolars extracted for orthodontic or dental purposes were used in this study as samples. …”
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Artemisia capillaris with two novel active compounds, Kawarayomogin I and II, inhibits HYBID (KIAA1199) expression as well as hyaluronic acid degradation by Kazal Boron Biswas, Yuka Kawai, Satoshi Nakagawa, Kyoko Kanai, Hiroyuki Kojima, Teruaki Masutani, Masayoshi Oyama, Arunasiri Iddamalgoda, Kotaro Sakamoto

“…Screening of various plant extracts was performed for the inhibition of histamine-induced mRNA expression of HYBID in normal human dermal fibroblasts (NHDF). The molecular size distribution of HA was evaluated by incubating fluorescein isothiocyanate (FITC)-labeled large HA (1200–1600 kDa) in NHDF for certain time followed by measuring different sizes of FITC-labeled HA in the cultured medium by HPLC. …”
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The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target by Reem Alharthi, Monica Sueiro-Olivares, Isabelle Storer, Hajer Bin Shuraym, Jennifer Scott, Reem Al-Shidhani, Rachael Fortune-Grant, Elaine Bignell, Lydia Tabernero, Michael Bromley, Can Zhao, Jorge Amich

“…We further showed that the structure of the ligand-binding pocket of the fungal enzyme differs significantly from its human counterpart, suggesting that specific inhibitors can be designed. …”
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Trifarotene alleviates skin photoaging injury by inhibition of JNK/c-Jun/MMPs by Fei Xuan, Yang Lele Zixin, Zhang Jingjing, Li Xiang, Pan Mengtian, Xu Guangchen, Zhang Cuixia, Liu Fei, Fang Weirong

“…This study aimed to investigate the therapeutic effects and mechanisms of trifarotene, a functional retinoic acid analog, on UV-irradiated photoaging ICR and BALB/c nude mice and UVB photodamaged human epidermal keratinocyte (HaCaT) cells by examining indicators such as collagen, oxidoreductase, and inflammatory factor presence through histochemical staining, Western blot, and ELISA. …”
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Fibrocyte enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity by Yi Sun, Yan Peng, Zezhuo Su, Kyle, K. H. So, Qiuji Lu, Maojiang Lyu, Jianwei Zuo, Yongcan Huang, Zhiping Guan, Kenneth M. C. Cheung, Zhaomin Zheng, Xintao Zhang, Victor Y. L. Leung

“…In this study, we performed an integrative analysis of multiple single-cell RNA sequencing datasets to interrogate the cellular heterogeneity and fibroblast-like entities in degenerative human NP specimens. We found that disc degeneration severity is associated with an enrichment of fibrocyte phenotype, characterized by CD45 and collagen I dual positivity, and expression of myofibroblast marker α-smooth muscle actin. …”
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Investigation of groundwater quality indices and health risk assessment of water resources of Jiroft city, Iran, by machine learning algorithms by Sobhan Maleky, Maryam Faraji, Majid Hashemi, Akbar Esfandyari

“…Abstract Assessing water quality is essential for acquiring a better understanding of the importance of water in human society. In this study, the quality of groundwater resources in Jiroft city, Iran, using artificial intelligence methods to estimate the groundwater quality index (GWQI) was evaluated. …”
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MGScoliosis: Multi-grained scoliosis detection with joint ordinal regression from natural image by Xiaojia Zhu, Rui Chen, Zhiwen Shao, Ming Zhang, Yuhu Dai, Wenzhi Zhang, Chuandong Lang

“…Extensive experiments demonstrate that our approach outperforms state-of-the-art methods as well as human performance, which provides a promising and economical solution to wide-range scoliosis screening. …”
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Current Status of Canine Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Veterinary Medicine by Tania Sultana, Soojung Lee, Hun-Young Yoon, Jeong Ik Lee

“…Although MSCs have been isolated from UCB of diverse species such as human, equine, sheep, goat, and canine, there are inherent limitations of using UCB from these species for the expansion of MSCs. …”
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Meta-analysis on the entomological effects of differentially treated ITNs in a multi-site experimental hut study in sub-Saharan Africa by Natalie Lissenden, John Bradley, Benjamin Menze, Charles Wondji, Constant Edi, Benjamin Koudou, Raphael N’Guessan, Koama Bayili, Abdoulaye Diabaté, Njelembo Mbewe, Basiliana Emidi, Jacklin Mosha, Alphaxard Manjurano, Graham Small, Welbeck Oumbouke, Sarah Jane Moore, Derric Nimmo, Janneke Snetselaar

“…These trials were conducted on a range of net products with different AIs, across a range of geographies in Africa (East and West), vector species (Anopheles gambiae, Anopheles coluzzii, Anopheles arabiensis, and Anopheles funestus), hut designs (East and West African style) and hosts (cows and humans). The combined data from these trials were analysed in a meta-analysis, and odds ratios for the effect of the different net designs on mortality and blood-feeding were estimated using mixed effects logistic regression. …”
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EFFORTS IN CONTROLLING COAL DUST HAZARDS IN THE STOCKPILE AREA OF A STEAM POWER PLANT (PLTU) by Alifiah Rizky Rosydah, Y. Denny Ardyanto Wahyudiono, Ahmad Imaduddin, Dani Nasirul Haqi, Meirina Ernawati

“…The smaller the particle size, the more harmful effects it can have on human health, such as bronchitis, decreased lung function, Chronic Obstructive Pulmonary Disease (COPD), Coal Worker's Pneumoconiosis (CWP), and other respiratory diseases. …”
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Anti-Apoptosis Effects of Green Tea in Diagnostic and Therapeutic Doses of Ionizing Radiation by Najmeh Anbiaee, Mohammad Taghi Bahreyni Toossi, Hosein Azimian, Zoha Sahebnasagh, Sepideh Abdollahi Dehkordi, Majid Kianmehr, samaneh soudmand salarabadi, Maryam Najafi Amiri

“…The aim of the present study is assessing the protective effect of green tea on lymphocytes affected by radiation injury.Material and Methods: Blood samples was obtained from four adults healthy human and lymphocytes were extracted. Afterward, lymphocytes were exposed to X-radiation by OPG, CBCT, CT and radiotherapy instruments. …”
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Does welfare technology contribute to security, activity, participation and independence within municipal elder care? A qualitative study protocol by Ingrid Hellström, Johannes Österholm, Åsa Larsson Ranada, Katarina Baudin, Vedrana B Baric

“…As the ageing population continues to rise, the strain on welfare resources both, human and financial, intensifies. The adoption of WT holds promise for enhancing the well-being of older persons, their significant others, organisations and caregiving staff. …”
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