Immunogenicity of HIV-1 <i>Env</i> mRNA and <i>Env-Gag</i> VLP mRNA Vaccines in Mice by Qi Ma, Jing Yang, Xiaoguang Zhang, Hongxia Li, Yanzhe Hao, Xia Feng

“…Background: The development of a protective vaccine is critical for conclusively ending the human immunodeficiency virus (HIV) epidemic. Methods: We constructed nucleotide-modified mRNA vaccines expressing HIV-1 Env and Gag proteins. …”
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miR-203 Expression in Exfoliated Cells of Tongue Coating Represents a Sensitive and Specific Biomarker of Gastroesophageal Reflux Disease by Xiuli Yan, Shengliang Zhu, Hui Zhang

“…MicroRNAs (miRNAs) have been implicated in the pathophysiology of numerous human diseases including gastroesophageal reflux disease (GERD). …”
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Object-Level Contrastive-Learning-Based Multi-Branch Network for Building Change Detection from Bi-Temporal Remote Sensing Images by Shiming Li, Fengtao Yan, Cheng Liao, Qingfeng Hu, Kaifeng Ma, Wei Wang, Hui Zhang

“…Buildings are fundamental elements of human environments, and detecting changes in them is crucial for land cover studies, urban expansion monitoring, and the detection of illegal construction activities. …”
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Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity by Boyuan Peng, Ziwei Li, Yong Cheng, Henghua Jiang, Qingsong Ye, Guangli Han

“…Methods We isolated and identified dental pulp stem cell-derived intracellular vesicles (DPSC-IV) from human dental pulp tissue. To investigate its effect, DPSC-IV was added to osteoblast or osteoclast differentiation medium. …”
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Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway by Song Yang, Lei Yao, Xiaolong Wang, Hao Sun, Chaogang Du, Chengpeng Song, Jingyu Fu, Yongjun Wu, Hongwu Huang, Chuansi Wang, Yongsen Wang, Yixiang Xie

“…The CCK-8 assay, migration assay, tube formation assay, qPCR, and Western blotting were performed in human umbilical vein endothelial cells (HUVECs). …”
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Eucalyptus-based livelihoods: enhancing household food security and resilience in Northwest Ethiopia by Fasika Belay, Fasika Belay, Messay Mulugeta, Teferee Makonnen

“…However, households that own eucalyptus plantations demonstrate a lower index for human capital than those without eucalyptus plantations. …”
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Reconstruction of climatic events from the 16th century in Transylvania: interdisciplinary analysis based on historical sources by Ovidiu Răzvan Gaceu, Tudor Caciora, Ștefan Baias, Cezar Morar, Mihai Dudaș, Marius Stupariu, Maria Maxim

“…Finally, the manuscript emphasizes the significant role of the climate in shaping the historical and socio-economic landscape of Transylvania in the 16th century, offering perspectives on the complex interactions between the climate and the human component.…”
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Grazing-Induced Habitat Degradation: Challenges to Giant Panda Survival Resulting from Declining Bamboo and Soil Quality by Huawei Tian, Ying Zeng, Zejun Zhang, Ming Lu, Wei Wei

“…Grazing is the primary human-induced disturbance affecting giant panda (<i>Ailuropoda melanoleuca</i>) habitats and has a severe impact on the long-term sustainability of the giant panda population. …”
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Stress-Driven Production of γ-Aminobutyric Acid Using Non-Conventional Yeast Strains <i>Kluyveromyces marxianus</i> JMY140K and <i>Metschnikowia reukaufii</i> JMY075 by Ting-Ting Fan, Chao Chen, Du-Wen Zeng, Feng-Lou Wang, Zhao-Xian Xu, Ming-Jie Jin, Yue Zou, Jun Li, Xin-Qing Zhao

“…The culture filtrate of <i>K. marxianus</i> JMY140K also showed promising activities in human skin cells. In addition, <i>K. marxianus</i> JMY140K could also produce GABA using rice straw hydrolysate, which indicated that it has the potential to produce GABA using renewable biomass. …”
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Programme de développement professionnel des fonctionnaires en vue de la création d’un environnement éducatif sûr dans le cadre de la loi martiale by Iryna Trubavina, Oleksandr Cherednychenko, Kirill Nedria, Nadiia Oliinyk

“…The research methodology of the article is a complex of scientific approaches that determined the content, methods and form of training: competencebased, axiological, systemic, risk-oriented approaches, public administration approach; approach for human rights. Research methods included analysis of theoretical sources, synthesis, modeling, oral interviews of educators, generalization of experience, and observation. …”
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The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research by Zihui Liu, Qing Cao, Wenqing Wang, Bowen Wang, Yilun Yang, Cory J. Xian, Tiejun Li, Yuankun Zhai

“…<i>Lactobacillus reuteri</i> is a Gram-positive rod-shaped bacterium that exists in various body parts of humans, including the gastrointestinal tract, urinary tract, skin, and so on. …”
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CULTURAL MORPHOLOGICAL AND BIOCHEMICAL CHARACTERISTICS OF BACILLUS SUBTILIS STRAINS by V. S. Rusaleyev, О. V. Pruntova, D. A. Vasilyev

“…Many studies in this feld are focused on Bacillus subtilis that is widespread in the environment and non-pathogenic for animals and humans. Results of tests of Bacillus subtilis for its biological properties and antagonistic activity aimed at optimization of methodical approaches for detection of strain with the highest antagonistic effect on some opportunistic microorganisms and their further use as probiotics are described. …”
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An Overview of Innovative Techniques to Improve Cervical Cancer Screening by Esther R. Nijhuis, Nathalie Reesink-Peters, G. Bea A. Wisman, Hans W. Nijman, Jelmer van Zanden, Haukeline Volders, Harry Hollema, Albert J. H. Suurmeijer, Ed Schuuring, Ate G. J. van der Zee

“…When available, data on cost– effectiveness of certain approaches will be provided. In short, Human Papillomavirus (HPV) DNA detection stands closest to implementation in nation-wide screening programs of all markers reviewed. …”
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Hyperglycemia Does Not Affect Iron Mediated Toxicity of Cultured Endothelial and Renal Tubular Epithelial Cells: Influence of L-Carnosine by Shiqi Zhang, Emmanouil Ntasis, Sarah Kabtni, Jaap van den Born, Gerjan Navis, Stephan J. L. Bakker, Bernhard K. Krämer, Benito A. Yard, Sibylle J. Hauske

“…We sought to assess if high glucose (HG) exposure makes cultured human umbilical vein endothelial cells (HUVECs) and renal proximal tubular epithelial cells (PTECs) more susceptible to metal induced toxicity and if this is ameliorated by L-carnosine. …”
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Drought risk management in agricultural sector with an emphasis on the socioeconomic dimension under Fuzzy Logic in the Sistan region by Zahra Sarani, Ali Sardar Shahraki, Mahdi Safdari

“…In addition to the legal risk, the human and social risks are also at lower ranks with a weight of 0.4. …”
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Model of Driver’s Eye Movement and ECG Index under Tunnel Environment Based on Spatiotemporal Data by Weiwei Qi, Bin Shen, Linhong Wang

“…The experimental schemes have been scientifically designed based on methods of traffic engineering and human factor engineering, which aims to test the driver’s spatiotemporal data of eye movement and ECG (electrocardiogram) index in the tunnel environment. …”
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The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells by Katarína Smolková, Petr Ježek

“…When oxidative phosphorylation is dormant, this mode causes substantial oxidative stress. Arg172 mutants of human IDH2—frequently found with similar mutants of cytosolic IDH1 in grade 2 and 3 gliomas, secondary glioblastomas, and acute myeloid leukemia—catalyze reductive carboxylation of 2-oxoglutarate and reduction to D-2-hydroxyglutarate, which strengthens the neoplastic phenotype by competitive inhibition of histone demethylation and 5-methylcytosine hydroxylation, leading to genome-wide histone and DNA methylation alternations. …”
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Plant Compounds Inhibit the Growth of W12 Cervical Precancer Cells Containing Episomal or Integrant HPV DNA; Tanshinone IIA Synergizes with Curcumin in Cervical Cancer Cells by Linda Saxe Einbond, Jing Zhou, Kunhui Huang, Mario R. Castellanos, Emeka Mbazor, Michael Balick, Hongbao Ma, James A. DeVoti, Stephen Redenti, Hsan-au Wu

“…This study explores the effects of plant compounds on human papillomavirus (HPV)-induced W12 cervical precancer cells and bioelectric signaling. …”
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Combination Antiretroviral Therapy for HIV in Rwandan Adults: Clinical Outcomes and Impact on Reproductive Health up to 24 Months by Brenda Asiimwe-Kateera, Nienke Veldhuijzen, Jean Paul Balinda, John Rusine, Sally Eagle, Joseph Vyankandondera, Julie Mugabekazi, Pascale Ondoa, Kimberly Boer, Anita Asiimwe, Joep Lange, Peter Reiss, Janneke van de Wijgert

“…Many patients were coinfected with herpes simplex virus type 2 (79–92%), human papillomavirus (38–53%), and bacterial sexually transmitted infections (STIs) with no differences between groups. …”
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An Intelligent Carbon-Based Prediction of Wastewater Treatment Plants Using Machine Learning Algorithms by Anwer Mustafa Hilal, Maha M. Althobaiti, Taiseer Abdalla Elfadil Eisa, Rana Alabdan, Manar Ahmed Hamza, Abdelwahed Motwakel, Mesfer Al Duhayyim, Noha Negm

“…This may leads to algal bloom and spoils aquatic life which is consumed by human. The presence of nitrogen and phosphorous elements is in the content of wastewater, and these elements are associated with eutrophication which should be prevented. …”
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