An Aptamer Sensor Based on Alendronic Acid-Modified Upconversion Nanoparticles Combined with Magnetic Separation for Rapid and Sensitive Detection of Thiamethoxam by Qian Huang, Lu Han, Hui Ma, Weijie Lan, Kang Tu, Jing Peng, Jing Su, Leiqing Pan

“…The widespread use of thiamethoxam has led to pesticide residues that have sparked global concerns regarding ecological and human health risks. A pressing requirement exists for a detection method that is both swift and sensitive. …”
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Smart Home Security: An Efficient Multi-Factor Authentication Protocol by Ghazaleh Sarbishaei, Amir Masoud Aminian Modarres, Farahnaz Jowshan, Fateme Zahra Khakzad, Hasti Mokhtari

“…The benefits of smart homes have made them a necessary part of modern human life. It is, however, essential to ensure the security of smart homes in order to protect personal information, prevent unauthorized access, provide physical security, and defend against cyberattacks. …”
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Biochar and carbon-negative technologies: exploring opportunities for climate change mitigation by Muhammad Ayaz, Sidra Tul Muntaha, Edita Baltrėnaitė-Gedienė, Zita Kriaučiūnienė

“…However, concerns regarding potential health implications for humans in agricultural contexts warrant further investigation and risk assessment to ensure safe and sustainable BC application. …”
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Cigarette smoke compromises macrophage innate sensing in response to pneumococcal infection by Wei-Chih Liao, Chia-Huei Chou, Mao-Wang Ho, Jo-Tsen Chen, Shu-Ling Chou, Yu-Tsen Huang, Ngoc-Niem Bui, Hui-Yu Wu, Chi-Fan Lee, Wei-Chien Huang, Chih-Ho Lai

“…Streptococcus pneumoniae, also known as pneumococcus, is one of the most common pathogens that colonizes the human respiratory tract, causing life-threatening infections. …”
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Transcriptional profiles analysis of effects of Toxoplasma gondii rhoptry protein 16 on THP-1 macrophages by Ningai Yang, Ningai Yang, Ningai Yang, Mingyang Li, Hong Yang, Jiaming Li, Tiantian Dang, Guangqi Li, Zhijun Zhao, Zhijun Zhao, Zhijun Zhao

“…However, the precise mechanisms underlying the involvement of type II ROP16 proteins in infection, inflammation, and other processes remain unknown.MethodsTo investigate the mechanism of action of gonococcal ROP16 proteins in human macrophages, we constructed a lentivirus overexpressing ROP16 and established stably transfected cell lines. …”
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Investigation of morphology changes in Karun River and its hazards (Case Study: Bandagir to Khorramshahr) by Amir Saffati, EzatAllah ghanavati, Hamid Alipour Dezdouli Asl

“…These changes have resulted in the destruction of natural habitats along the river, the ability to self-purify water, sudden floods, threatening and damaging human structures, agriculture, and so on.…”
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Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention by Sonia Youhanna, Aurino M. Kemas, Shane C. Wright, Yi Zhong, Britta Klumpp, Kathrin Klein, Aikaterini Motso, Maurice Michel, Nicole Ziegler, Mingmei Shang, Pierre Sabatier, Aimo Kannt, Hongda Sheng, Nuria Oliva‐Vilarnau, Florian A. Büttner, Brinton Seashore‐Ludlow, Jonas Schreiner, Maike Windbergs, Martin Cornillet, Niklas K. Björkström, Andreas J. Hülsmeier, Thorsten Hornemann, Jesper V. Olsen, Yi Wang, Roberto Gramignoli, Michael Sundström, Volker M. Lauschke

“…To narrow the translational gap in the development of pharmacological MASH treatments, a 3D liver model from primary human hepatocytes and non‐parenchymal cells derived from patients with histologically confirmed MASH was established. …”
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MCT1 lactate transporter blockade re-invigorates anti-tumor immunity through metabolic rewiring of dendritic cells in melanoma by Camille Niveau, Mélanie Cettour-Cave, Stéphane Mouret, Eleonora Sosa Cuevas, Mylene Pezet, Benoît Roubinet, Hugo Gil, Florence De Fraipont, Ludovic Landemarre, Julie Charles, Philippe Saas, Caroline Aspord

“…Here we explore metabolic features of human DC subsets (cDC2s, cDC1s, pDCs) in melanoma, at single cell level, using the flow cytometry-based SCENITH (Single-Cell ENergetIc metabolism by profiling Translation inHibition) method. …”
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An Overview on the Role of Relative Humidity in Airborne Transmission of SARS-CoV-2 in Indoor Environments by Ajit Ahlawat, Alfred Wiedensohler, Sumit Kumar Mishra

“…Based on earlier studies, a relative humidity of 40–60% was found to be optimal for human health in indoor places. Thus, it is extremely important to set a minimum relative humidity standard for indoor environments such as hospitals, offices and public transports for minimization of airborne spread of SARS-CoV-2.…”
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Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/β-Catenin by Yufeng Zhang, Huaxin Deng, Zhiqiang Yang, Zhe Chen, Sheng Zhang, Yufan Zhu, Min Yang, Houcheng Zhong, Fuling Zhou, Yuanlong Xie, Lin Cai

“…We use a single high-dose ionizing radiation (6Gy) to analyze the effect of radiotherapy on osteoblast function. Human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) were cocultured with irradiated osteoblasts to examine their therapeutic effects and mechanisms on osteoblast injury. …”
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Design, synthesis, and in vitro, in vivo, and in silico evaluation of novel substituted 1,3,4-thiadiazole derivatives as anticonvulsant agents by Tulika Anthwal, Swati Pant, Preeti Rana, Sumitra Nain

“…The synthesized compounds were assayed for in vitro human carbonic anhydrase (CA) inhibition against two isoforms II and IX. …”
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Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review by Raghavendra B. Narasimha, Singireddy Shreya, Vijay Anand Jayabal, Vikas Yadav, Prasana Kumar Rath, Bidyut Prava Mishra, Sudhakar Kancharla, Prachetha Kolli, Gowtham Mandadapu, Sudarshan Kumar, Ashok Kumar Mohanty, Manoj Kumar Jena

“…Although there are substantial studies revealing the treatment of human degenerative diseases using stem cells, this is yet to be explored in livestock animals. …”
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Autoantibody to MDM2: A Potential Serological Marker of Systemic Lupus Erythematosus by Yuan Liu, Liping Dai, Weihong Liu, Guixiu Shi, Jianying Zhang

“…Systemic lupus erythematosus (SLE) is one of the systemic autoimmune diseases characterized by the polyclonal autoantibody production. The human homologue of the mouse double minute 2 (MDM2) is well known as the negative regulator of p53. …”
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Cyberattack Monitoring Architectures for Resilient Operation of Connected and Automated Vehicles by Zulqarnain H. Khattak, Brian L. Smith, Michael D. Fontaine

“…The deployment of connected and automated vehicles (CAVs) may enhance operations and safety with little human feedback. Automation requires the use of communication and smart devices, thus introducing potential access points for adversaries. …”
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miR-224-5p Attenuates Allergic Responses in Mice with Allergic Rhinitis by Modulating the Th1/Th2 Response by Yuxiao Li, Ran An, Mingjin Wu, Jiayan He, Xiaoguang He

“…In this work, the mechanism by which miR-224-5p regulates AR in vivo and in vitro was examined. Methods. Human nasal epithelial cells (HNEpCs) were used to establish an AR cell model induced by Der P1, and C57BL/6 mice were used to establish an AR animal model induced by OVA (ovalbumin). …”
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Ethno-cultural particularity of English, French and Russian phrasiological units with components of names of domestic animals by E. N. Belaya

“…contains stereotyped representations of arrogant behavior of a person’s senseless activity who poses as the other person than he is in reality; of touch with Scottish realia and literature; 2) the figurative basis of French P.U. contains patterned and stereotyped representations of a person who works by the sweat of his brow, of the interaction of man and a horse, of a bad French, of a drunkard, a silly man who is fond of bombastic speech, of a cruel man; 3) the figurative basis of Russian P.U. contains stereotyped representations of a ridiculously dressed person, a pattern of human obstinacy; of touch with Russian peasant’s way of life. …”
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Exploring the Potential of Selenium-Containing Amine (Se-AMA) to Enhance Photosynthesis and Leaf Water Content: New Avenues for Carbonic Anhydrase Modulation in <i>Arabidopsis thal... by Sara Beltrami, Francesca Alderotti, Antonella Capperucci, Damiano Tanini, Cecilia Brunetti, Francesco Ferrini, Ermes Lo Piccolo, Antonella Gori

“…We hypothesize that the modulators of human CAs could affect plant physiology. Our research demonstrated that foliar treatments with a synthetic selenium-containing CA activator (Se-AMA) influenced the physiological performances of <i>Arabidopsis thaliana</i>. …”
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Ensemble automated approaches for producing high‐quality herbarium digital records by Robert P. Guralnick, Raphael LaFrance, Julie M. Allen, Michael W. Denslow

“…Discussion This work shows that an ensemble approach has particular value for creating high‐quality digital data records, even for complicated label content. While human validation is still needed to ensure the best possible quality, automated approaches can speed digitization of herbarium specimen labels and are likely to be broadly usable for all natural history collection types.…”
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Quercetin attenuates cisplatin-induced fatigue through mechanisms associated with the regulation of the HPA axis and MCP-1 signaling by Cheng-Hung Chuang, Yu-An Tai, Ting-Jing Wu, Ying-Jui Ho, Shu-Lan Yeh, Shu-Lan Yeh

“…The main objective of the present study was to investigate whether quercetin regulates the hypothalamic-pituitary-adrenal (HPA) axis and chemoattractant protein-1 (MCP-1) signaling, two factors contributing to CRF in mice exposed to cisplatin.MethodsMale BALB/c mice were randomly assigned to the following five groups for 15 weeks: Control, CDDP, CDDP+TAK779 (an antagonist of MCP-1 receptor, human CC chemokine receptor R2 (CCR2)), CDDP+OQ (a diet containing 1% quercetin) and CDDP+IQ (quercetin given by ip, 10 mg/kg, 3 times/week).ResultsThe results first showed that OQ and IQ significantly increased grip strength and locomotor activity, decreased plasma cortisol/corticosterone levels, and decreased the corticotropin releasing hormone (CRH) mRNA level in the brain tissues in mice exposed to CDDP. …”
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Developing a GIS Model for Identifying Bear Corridors with Open-Source Data: The Romanian Context by Sanda Roșca, Alexandru Chira, Iuliu Vescan, Ștefan Bilașco, Ioan Fodorean, András-István Barta, Vasile Ceuca, Paul Sestraș

“…The fragmentation of the bears’ habitat is the main cause of conflict occurrences between bears and the human population, which have occurred increasingly often in recent years. …”
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