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20661
Targeting ferroptosis for improved radiotherapy outcomes in HPV‐negative head and neck squamous cell carcinoma
Published 2025-02-01“…To enhance the efficacy of radiotherapy (RT) in human papillomavirus (HPV)‐negative head and neck squamous cell carcinoma (HNSCC), we explored targeting ferroptosis, a regulated cell death process. …”
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20662
Comparison of HER2-Targeted Antibodies for Fluorescence-Guided Surgery in Breast Cancer
Published 2021-01-01“…Although therapeutic advances have led to enhanced survival in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer, detection of residual disease remains challenging. …”
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20663
Binding and cleavage of pro-urokinase by a tegument extract of Fasciola hepatica newly excysted juveniles activate the host fibrinolytic system
Published 2025-01-01“…The trematode Fasciola hepatica is the leading cause of fasciolosis, a major disease of livestock and an emerging zoonosis in humans. Infection success depends on the ability of F. hepatica newly excysted juveniles (FhNEJ) to penetrate the host intestinal wall, a process that remains incompletely understood. …”
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20664
Composition of Anthocyanins in Colored Grains and the Relationship of Their Non-Acylated and Acylated Derivatives
Published 2019-03-01“…Bearing in mind that cereals are widely grown crops, anthocyanins-rich colored grains could be used as a functional food ingredient that provide health benefits to a large part of human world's population. This study investigated composition and content of anthocyanins in the grain of blue popping maize, deep purple maize, purple wheat and black soybean. …”
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20665
Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux
Published 2015-01-01“…Chemotactic agents, cytokines, and particulate molecules were used to stimulate human neutrophils. MSU crystals, PMA, and H2O2 induced the release of S100A8, S100A9, and S100A12 homodimers, as well as S100A8/A9 heterodimer. …”
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20666
Barriers to and facilitators of access to mental health services among pregnant adolescents and young mothers in Belize
Published 2025-02-01“…The second theme was health systems and highlighted a lack of trust and confidence in health care providers, as well as limited access to mental health services due to insufficient human resources, long waiting times, and transportation costs. …”
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20667
Identification and interpretive ranking of factors affecting the improvement of agility in business process management
Published 2023-11-01“…After that, the results showed that environmental awareness, knowledgeable and competent human resources, organizational learning dimension, contingent and appropriate structures, governance, improvisation-based strategy-making, technological infrastructure, dynamic adaptation, culture, and creative sustainability are prioritized, respectively.Originality/Value: Using soft operations research techniques, including the interpretive ranking process, in designing an agile model for managing business processes will significantly help process organizations in complex and dynamic environments to simultaneously exploit the benefits of stability in managing processes and dynamism coming from being agile.…”
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20668
The Influence of Multi-Sensory Perception on Public Activity in Urban Street Spaces: An Empirical Study Grounded in Landsenses Ecology
Published 2024-12-01“…Understanding how various urban street spatial characteristics affect public behavior, alongside the role of multi-sensory perception, enables designers and planners to create more human-centered urban environments. Grounded in landsenses ecology, this study employs correlation analysis, regression analysis, and Partial Least-Squares Structural Equation Modeling (PLS-SEM) to examine the effects of different urban street spatial characteristics on public behavior and the mediating role of multi-sensory perception. …”
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20669
Ester derivatives of Dictyostelium differentiation-inducing factors exhibit antibacterial activity, possibly via a prodrug-like function
Published 2025-01-01“…Results In vitro tests revealed that the antibacterial activity of 3 and 4 was lost in the presence of human serum albumin (HSA), suggesting that HSA might inhibit their effectiveness. …”
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20670
The Myth of Air Purifier in Mitigating the Transmission Risk of SARS-CoV-2 Virus
Published 2022-01-01“…Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious disease that emerged in December of 2019, threatening human health and leading to global public health crises. …”
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20671
Extreme high temperatures and heatwave events across Europe in 2023
Published 2025-01-01“…With global mean temperatures reaching record highs in 2023, many regions experienced successive heatwaves, causing negative impacts on human health, social economy, and ecosystems. Europe is among the continents that experienced a series of extreme heatwaves over large areas in the year. …”
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20672
A New Metaheuristic-Based Hierarchical Clustering Algorithm for Software Modularization
Published 2020-01-01“…Experimental results on seven folders of Mozilla Firefox with different functionalities and five other software systems show that the TDHC produces modularization closer to the human expert’s decomposition (i.e., directory structure) than the other existing algorithms. …”
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20673
The National Police of Ukraine as an object to combat illegal migration
Published 2023-09-01“…This article has a scientific and theoretical significance based on the relevance of illegal migration in our country and combating human trafficking as one of the factors that threaten national security and law and order.…”
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20674
Neural progenitor cell-derived exosomes in ischemia/reperfusion injury in cardiomyoblasts
Published 2025-02-01“…Abstract The physiologic relationship between the brain and heart is emerging as a novel therapeutic target for clinical intervention for acute myocardial infarction. In the adult human brain, vestigial neuronal progenitor stem cells contribute to neuronal repair and recovery following cerebral ischemic injury, an effect modulated by secreted exosomes. …”
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20675
«CULTURAL REVOLUTION» IN THE USSR IN 1929–1932 AND THE EARLY ATTACKS AGAINST N.I. VAVILOV’S SCHOOL. A STUDY BASED ON DOCUMENTS FROM ST. PETERSBURG ARCHIVES
Published 2014-12-01“…Lysenko was a competition between two rival academic schools for financial, material, and human resources. Already in the early attacks against Vavilov, which began in the years of the «cultural revolution», before T.D. …”
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20676
Lewy body diseases and the gut
Published 2025-01-01“…Recent experimental and human observational studies raise the possibility that pathogenic alpha-synuclein (⍺-syn) might develop in the GI tract and subsequently spread to susceptible brain regions. …”
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20677
Calculation of Involved and Noninvolved Organs Doses in Carbon Therapy of Brain Tumor Using GEANT4 Simulation Toolkit
Published 2024-10-01“…Introduction: This study used the GEANT4 Monte Carlo toolkit for radiation transport simulations in brain carbon therapy, incorporating a human phantom model to accurately assess dose delivery to targeted and non-targeted organs. …”
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20678
First Autologous Cell Therapy of Cerebral Palsy Caused by Hypoxic-Ischemic Brain Damage in a Child after Cardiac Arrest—Individual Treatment with Cord Blood
Published 2013-01-01“…Therefore, based on experimental evidence, we explored the therapeutic potential of human cord blood, known to contain stem cells, to examine the functional neuroregeneration in a child with cerebral palsy after cardiac arrest. …”
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20679
A deep learning model based on RGB and hyperspectral images for efficiently detecting tea green leafhopper damage symptoms
Published 2025-03-01“…However, traditional methods of recognizing and classifying the damage symptoms of this pest rely on human visual observation, which is time-consuming, labor-intensive, and subjective. …”
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20680
Enhancing Orthopedic Surgery and Treatment Using Artificial Intelligence and Its Application in Health and Dietary Welfare
Published 2022-01-01“…The current decade has seen an increased usage of high-end digital technologies like machine learning in the field of health care services which enable in supporting and performing different functions with less or no human interventions. The application of machine learning tools in the orthopedic area is gaining more popularity as it can support in analyzing the issues in a more comprehensive manner, provide accurate data, support in forecasting the pattern. …”
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