Development of a broad-spectrum epitope-based vaccine against Streptococcus pneumoniae. by Md Nahian, Muhammad Shahab, Md Rasel Khan, Shopnil Akash, Tanjina Akhtar Banu, Murshed Hasan Sarkar, Barna Goswami, Sanjana Fatema Chowdhury, Mohammad Ariful Islam, Ahmed Abu Rus'd, Shamima Begum, Ahashan Habib, Aftab Ali Shaikh, Jonas Ivan Nobre Oliveira, Shahina Akter

“…Docking analysis of the vaccine candidate by ClusPro demonstrated robust and stable binding interactions between the MEV and toll-like receptor 4 in both humans and animals. The iMOD server and Amber v.22 tool has verified the stability of the docking complexes. …”
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Analysis of Noise Pollution during Dussehra Festival in Bhubaneswar Smart City in India: A Study Using Machine Intelligence Models by Sourav Kumar Bhoi, Chittaranjan Mallick, Chitta Ranjan Mohanty, Ranjan Soumya Nayak

“…However, since this sound pollution is creating a risk to human health, regular monitoring is strictly needed. …”
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Investigation study of face mask consumption in Malaysia and its impact on environment by Low Chung-Yu, Bee Soo-Tueen, Law Yung-Siang, Lee Tin-Sin, Bee Soo-Ling

“…In overall, RFL washable face mask is found to provide a lower environmental impact when compared to 3-ply surgical face mask in terms of the ReCiPe midpoint and endpoint indicator, which included Global Warming Potential, Photochemical Oxidant Formation Potential, Toxicity Potential, Ecosystem Quality, Human Health and Resource Depletion.…”
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The Assessment of CDX1, IHH, SHH, GATA4, FOXA2, FOXF1 in Congenital Intra-Abdominal Adhesions by Helēna Freijere Pope, Māra Pilmane, Anna Junga, Aigars Pētersons

“…This research examines the expression of Caudal Type Homeobox 1 (CDX1), Indian Hedgehog (IHH), Sonic Hedgehog (SHH), GATA Binding Protein 4 (GATA4), Forkhead Box A2 (FOXA2) and Forkhead Box F1 (FOXF1) gene expression in human abdominal congenital adhesion fibroblast and endothelium cells by chromogenic in situ hybridization, with the aim of elucidating their potential association with the etiology of congenital intra-abdominal adhesion band development. …”
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When surgery leaves more than just scars: The curious case of gossypiboma— A case report and literature review by Syed Muhammad Ali, MBBS, Affan Faisal, MBBS, Talha Ashraf Zia, MBBS, Fatima Shahid, MBBS, Muhammad Nabeel Saddique, MBBS, Anurag Jha, MBBS, Atif Hussain Sarwar, MD, Javed Iqbal, RN, PhD

“…This case highlights the need for the fusion of medicine with technology< which prompts the use of innovations such as RFID-tagged sponges and electronic counting to minimize human error. Increased awareness and reporting of gossypibomas will aid in their timely diagnosis and management, ultimately reducing patient morbidity and associated legal challenges.…”
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Postgraduate education at the Juan José Apolinaire Pennini polyclinic in Cienfuegos by Marisela García de la Torre, Dayme Rodríguez Fumero, Zulema González Abreu, Grisel Vidal Cabrera, Carlos Manuel Crespo Tamayo

“…<p><strong>Background:</strong> postgraduate education constitutes the upper stage of the educational cycle and responds to the need to train human resources of the highest level, both professionally, as well as in teaching and research.…”
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Spatiotemporal Variation Characteristics of Water Pollution and the Cause of Pollution Formation in a Heavily Polluted River in the Upper Hai River by Chunfang Meng, Xiaoyu Song, Kening Tian, Bingxiao Ye, Tianxiu Si

“…Blackening and odorization of heavily polluted rivers has become a serious concern and threat to ecological and human health. This paper aims to gain a deeper understanding of changes in water pollution and the cause of pollution formation in a heavily polluted river in the upper Hai River. …”
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Proton magnetic resonance spectroscopy-based evaluation of metabolic abnormalities in the right dorsolateral prefrontal cortex and caudate nucleus in treatment-naïve patients with... by Gagan Hans, Uma Sharma, Novy Gupte, Ragul Ganesh, Vaibhav Patil, Pratap Sharan

“…The 1H-MRS experiments were performed using the 3 Tesla (3T) human MR scanner, and absolute concentrations of metabolites were estimated using the LC model. …”
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PERFORMANCE EVALUATION OF NATURAL COAGULANTS FOR WASTEWATER TREATMENT by Muhammad Imran, Shahbaz Nasir Khan, Saba Abid, Hafiz Muhammad Safdar Khan

“…But these coagulants have bad effects on human health. So this study is to focus on alternatives of these coagulants by finding efficient natural coagulants. …”
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Resin composite aggregated S-PRG particles are not superior to non-S-PRG under microcosm biofilm by Andrea Freire, Victor Augusto Alves Bento, Eduardo Inocente Jussiani, Avacir Casanova Andrello, Maria Carolina Silva Marques

“…Abstract This study assessed the effect of composite resins, aggregated or not with S-PRG particles, and the use of toothpaste in controlling demineralization and bacterial growth. Human molars were distributed into 3 groups: control (CT) – sound teeth, Beautifil Bulk Restorative System (aggregated with S-PRG) (BB), Filtek One Bulk Fill (without S-PRG) (FB). …”
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PD-1 Blockade in Advanced Melanoma in Patients with Hepatitis C and/or HIV by Diwakar Davar, Melissa Wilson, Chelsea Pruckner, John M. Kirkwood

“…Given hypothesized risk of triggering exacerbations of autoimmune diseases and/or chronic viral infections, clinical trials (including regulatory studies) evaluating checkpoint blocking antibodies PD-1 and CTLA-4 have excluded patients with autoimmune diseases, chronic hepatitis B/C virus (HBV/HCV), and/or human immunodeficiency virus (HIV) infections. Herein, we describe two patients with advanced melanoma and concomitant HCV/HIV infections treated with PD-1 inhibitor pembrolizumab. …”
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Feasibility and potential effect of a pilot blended digital behavior change intervention promoting sustainable diets over a year by Ujué Fresán, Miguel López-Moreno, Sergi Fàbregues, Paquito Bernard, Anna Boronat, Vera Araújo-Soares, Laura M. König, Joren Buekers, Guillaume Chevance

“…Abstract Well-designed effective interventions promoting sustainable diets are urgently needed to benefit both human and planetary health. This study evaluated the feasibility, acceptability, and potential impact of a pilot blended digital intervention aimed at promoting sustainable diets. …”
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Real-Time Needle Force Modeling for VR-Based Renal Biopsy Training with Respiratory Motion Using Direct Clinical Data by Feiyan Li, Yonghang Tai, Qiong Li, Jun Peng, Xiaoqiao Huang, Zaiqing Chen, Junsheng Shi

“…In this paper, a dynamic biomechanics experimental framework is designed to achieve a highly immersive haptic sensation during the biopsy therapy with human respiratory motion; it is the first time to introduce the idea of periodic extension idea into the dynamic percutaneous force modeling. …”
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Development of Lettuce Growth Monitoring Model Based on Three-Dimensional Reconstruction Technology by Jun Ju, Minggui Zhang, Yingjun Zhang, Qi Chen, Yiting Gao, Yangyue Yu, Zhiqiang Wu, Youzhi Hu, Xiaojuan Liu, Jiali Song, Houcheng Liu

“…However, conventional methods of growth monitoring, although simple and direct, have limitations such as destructive sampling, reliance on human experience, and slow detection speed. This study estimated the fresh weight of lettuce (<i>Lactuca sativa</i> L.) in a plant factory with artificial light based on three-dimensional (3D) reconstruction technology. …”
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Identifying the Economic Criteria for Sustainable Development Reporting Based on Islamic Texts at the Level of Companies by Morteza Yousefi, Rasoul Baradaran Hassanzadeh, Ali Reza Radbin, Mohammad Ali Rabbipoor, Saeed Hassanzadeh Delgsha

“…From the point of view of Islamic teachings, as long as a balanced human culture does not rule a society, we can not expect development from it.One of the main pillars and components of this development and culture is a balanced economy. …”
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The Effect of Crank Length Changes from Cycling Rehabilitation on Muscle Behaviors by Lu Zongxing, You Shengxian, Wei Xiangwen, Chen Xiaohui, Jia Chao

“…In addition, the relationship between crank length and muscle biological force was analyzed with the AnyBody Modeling System™, a human simulation modeling software based on the Hill-type model. …”
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The ultradian rhythm of glucocorticoid secretion and the time course of target gene regulation by V. M. Merkulov, N. V. Klimova, T. I. Merkulova

“…Glucocorticoid hormones (cortisol in humans and corticosterone in rodents) are secreted in discrete pulses during a day with a periodicityof approximately 1 h (ultradian rhythm), and this pattern is also maintained in plasma and extracellular fluid. …”
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The Effects of Different Phase on Independent Visual Fields SSVEP Responses by Dalu Zheng, Songyun Xie, Xinzhou Xie, Michael Scholz, Hao Tang

“…Utilizing the phase of the stimulus in addition to its frequency creates a new dimension and thus helps significantly to overcome frequency limitations in SSVEP research which otherwise dramatically hinder the read-out due to the prominent lowpass nature of the human head.…”
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Epac1 Restores Normal Insulin Signaling through a Reduction in Inflammatory Cytokines by Elizabeth Curtiss, Youde Jiang, Li Liu, Claire Hawthorne, Jessica Zhang, Jena J. Steinle

“…Whole retinal lysates from Epac1 floxed and endothelial cell-specific Epac1 knockout mice were used to investigate proteins involved in the insulin signaling cascade. Primary human REC were cultured in normal and high glucose followed by Epac1 agonist treatment or transfection with IL-1β or TNFα siRNA for protein analyses of insulin signaling proteins. …”
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Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity by Evelyn F Okal, Philip A. Romero, Pete Heinzelman

“…Abstract Background Angiotensin-Converting Enzyme 2 (ACE2) is a crucial peptidase in human peptide hormone signaling, catalyzing the conversion of Angiotensin-II to Angiotensin-(1–7), which activates the Mas receptor and elicits vasodilation, increased blood flow, reduced inflammation, and decreased pathological tissue remodeling. …”
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