Vedolizumab for inflammatory bowel diseasesI by Igor L. Khalif, M. V. Shapina

“…The vedolizumab is anti-α4β7-integrin humanized class IgG1 antibodies which suppresses migration of leukocytes in intestinal tissue, interfering thereby with development of pathologic inflammation. …”
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Experimental opisthorchiasis: a study of blood cells, hematopoiesis and startle reflex in laboratory animals by D. F. Avgustinovich, I. A. Orlovskaya, L. B. Toporkova, G. B. Vishnivetskaya, A. V. Katokhin, M. N. Lvova, E. V. Kashina, N. P. Bondar, N. A. Feofanova, V. A. Mordvinov

“…One of the species of the family Opisthorchiidae, Opisthorchis felineus (O. felineus), causes severe disturbances in humans and animals, and so it is the subject of important research studies. …”
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Knowledge, Attitude, and Practice Regarding High Salt Intake and Association With Hypertension Among Rural Women in Chandpur District of Bangladesh by Pradip Chandra, Aminul Islam, Shahara Robertson, Abu‐Al‐Rafe, Md. Abu Sayed, Afra Anjum Ahona, Mst. Nadira Parvin, Pradip Sen Gupta

“…ABSTRACT Background and Aims The human body requires a relatively little quantity of sodium to transmit nerve impulses, contract and relax muscles, and maintain appropriate water and mineral balance and which is typically added from diets. …”
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Chromosome 1 Sequence Analysis of C57BL/6J-Chr1KM Mouse Strain by Fuyi Xu, Tianzhu Chao, Yiyin Zhang, Shixian Hu, Yuxun Zhou, Hongyan Xu, Junhua Xiao, Kai Li

“…Further functional annotation identified 155 genes harboring potentially functional variants, among which 27 genes have been associated with human diseases. We then performed sequence similarity and Bayesian concordance analysis using the SNPs identified on Chr 1 and their counterparts in three subspecies, Mus musculus domesticus, M. m. musculus, and M. m. castaneus. …”
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Investigative genetic genealogy practices warranting policy attention: Results of a modified policy Delphi. by Christi J Guerrini, Louiza Kalokairinou, Jill O Robinson, Whitney Bash Brooks, Stephanie M Fullerton, Sara Huston, Jacklyn Dahlquist, Diana Madden, Norah Crossnohere, Nicola Campoamor, John F P Bridges, Amy L McGuire

“…A technique known as investigative genetic genealogy (IGG) was first introduced to criminal investigations in 2018, and it has since been used by U.S. law enforcement to help identify hundreds of criminal perpetrators and unidentified human remains. As expertise in IGG grows, policymakers have shown interest in regulating it. …”
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Prostanoid Receptor Subtypes and Its Endogenous Ligands with Processing Enzymes within Various Types of Inflammatory Joint Diseases by Mohammed A. Al-Madol, Mohammed Shaqura, Thilo John, Rudolf Likar, Reham Said Ebied, Magdi M. Salih, Sascha Treskatsch, Michael Schäfer, Shaaban A. Mousa

“…Our findings show a distinct expression profile of EP receptor subtypes and PGE2 as well as the corresponding processing enzymes in human synovium that modulate the inflammatory process in JT, OA, and RA patients.…”
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Frequency of Trypanosoma cruzi Infection in Synanthropic and Wild Rodents Captured in a Rural Community in Southeast of Mexico by Ivonne Hernández-Cortazar, Karla Cecilia Amaya Guardia, Marco Torres-Castro, Karla Acosta-Viana, Eugenia Guzmán-Marín, José Israel Chan-Pérez, Antonio Ortega-Pacheco, Roger I. Rodríguez-Vivas, Rodrigo Medina-Pinto, Matilde Jiménez-Coello

“…The active and chronic infection of T. cruzi in synanthropic or wild rodents of the rural community of southern Mexico evidences the natural infection in these reservoirs which contribute to maintaining the agent in the wild and domestic environments and can represent a risk of infection for the human population when the vector is present.…”
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Differential Susceptibility to Propofol and Ketamine in Primary Cultures of Young and Senesced Astrocytes by Liang Huang, Ferit Tuzer, Abigail Murtha, Michael Green, Claudio Torres, Henry Liu, Shadi Malaeb

“…Oxidative stimulus was applied to commercially available fetal cell lines of human astrocytes in vitro to induce morphological changes in cellular senescence. …”
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Copy Number Variation of UGT 2B Genes in Indian Families Using Whole Genome Scans by Avinash M. Veerappa, Prakash Padakannaya, Nallur B. Ramachandra

“…We investigated the presence of CNVs in UGT2B genes in 31 members from eight Indian families using Affymetrix Genome-Wide Human SNP Array 6.0 chip. Results. Our data revealed >50% of the study members carried CNVs in UGT2B genes, of which 76% showed deletion polymorphism. …”
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Vaginal Dysplasia and HIV: An African American and Caribbean American Cohort Study by Lunthita M. Duthely, Jose A. Carugno, Cayla Y. Suthumphong, Erica B. Feldman, JoNell E. Potter

“…In the US, vaginal infections are more prevalent among Caribbean women, and these infections contribute to higher rates of Human Papilloma Virus (HPV). Given the high rate of anogenital cancers in the Caribbean and the high rates of HPV among Caribbean women in the US, we sought to describe the occurrence of VaIN in a cohort of Black non-Hispanic WLWH. …”
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An Enhanced Vehicle-to-Vehicle Wireless Power Transfer System for Electric Vehicle Applications Using a Reconfigurable Coil Approach by Venkatesan Ramakrishnan, Dominic Savio A, Mohammad Shorfuzzaman, Waleed Mohammed Abdelfattah

“…However, the conventional plug-in approach limits safety and human intervention aspects. Recent advancements in wireless power transfer (WPT) offer both convenience and reliable power exchange, making them the most suitable approach for V2V technology. …”
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Role of CD117 and mast cells in periodontal diseases: Histological and immunohistochemical study by Fatin L. Khaphi, Hanaa Ali Hussein, Oula Fouad Hameed, Huda Jassem Jebur, Zahra Kadhum Saeed

“…Thus, an increase in mast cells in human periodontal diseases suggests that these cells are crucial for developing chronic periodontitis. [ J Adv Biotechnol Exp Ther 2025; 8(1.000): 182-191]…”
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5-Fluorouracil-β-Cyclodextrin conjugates:Linker strategies to enhance the anticancer efficacy and reduce the side effects by Liangliang Hu, Ting Meng, Davies Marabada, Zhichao Jin, Qing Huang, Shijie Wei, Zhizhong Wang

“…The cytotoxicity assays on human colon cancer cell lines HT-29 and normal colon epithelial cells NCM-460 demonstrated that the IC50 value of the 5-FUBA-β-CD conjugate for the HT-29 cells was 38.72 ± 0.13 μM, indicating superior antitumor activity compared to both 5-FUBA-β-CD and 5-FU. …”
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Analysis on Quantified Self-Behavior of Customers in Food Consumption under the Perspective of Social Networks by Lei Lei, Yaling Zhu, Qiang Liu

“…In addition to obtaining information through their own human capital for quantitative activities, consumers will also obtain information through social networks. …”
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Date pomace polysaccharides-capped selenium nanoparticles: Biosynthesis, optimization, physicochemical characterization, biological activities, stability and gut microbiota modulat... by Gafar Babatunde Bamigbade, Athira Subhash, Mohammed Abdin, Hebah Jarusheh, Basim Abu-Jdayil, Shao-Quan Liu, Giovanni Palmisano, Abdelmoneim Ali, Afaf Kamal Eldin, Mutamed Ayyash

“…The MPS-NPS characteristics, digestibility and impact on human gut microbiota were investigated. The MPS-NPS were well-stabilized, spherical particles averaging 65.4 nm in size, with PDI (0.032), zeta potential (–21.07 mV) and notable antioxidant activity (82.7 % DPPH, 68.9 % ABTS, 491.0 µg/mL FRAP, and 961.2 µg/mL TAC at 100 mg/L). …”
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Successful treatment with efgartigimod as an add-on therapy for acute attack of anti-NMDA receptor encephalitis: a case report by Huasheng Huang, Yizhi Wei, Huihui Qin, Guangshun Han, Jie Li

“…Case presentation We present a case of a 42-year-old male patient diagnosed with anti-NMDAR encephalitis, initially treated with intravenous methylprednisolone(IVMP) and human immunoglobulin (IVIG) without clinical improvement. …”
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The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells by Faranak Korfi, Hossein Javid, Reza Assaran Darban, Seyed Isaac Hashemy

“…Substance P (SP), a peptide released by sensory nerves, increases cellular excitability by activating the neurokinin-1 receptor (NK1R) in several human tumor cells. Aprepitant is a potent and long-lasting NK1R antagonist, considered a new agent for inhibiting proliferation and induction of apoptosis in malignant cells. …”
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Lecanemab’s Path Forward: Navigating the Future of Alzheimer’s Treatment in Europe Amidst the EMA's Rejection by Alessandro Martorana, Chiara Giuseppina Bonomi, Martina Gaia Di Donna, Caterina Motta

“…Abstract Lecanemab (Leqembi©, Biogen), a humanized anti-amyloid-beta monoclonal antibody, has been approved for early-stage Alzheimer’s disease (AD) in several countries, including the US and Japan. …”
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Ecological relationships of Haemaphysalis longicornis Neumann with other tick species on wildlife hosts at cow–calf farms implementing integrated pest management in eastern Tenness... by Rebecca A. Butler, Lisa I. Muller, Dan Grove, Rebecca T. Trout Fryxell, Ala Tabor

“…Longhorned tick (Haemaphysalis longicornis) is an invasive tick species that parasitizes a variety of vertebrate hosts and transmits pathogens affecting humans and livestock in the United States (US). Unfortunately, the behaviour of this tick at the wildlife–livestock interface is not well understood. …”
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Detection of N-Glycolyl GM3 Ganglioside in Neuroectodermal Tumors by Immunohistochemistry: An Attractive Vaccine Target for Aggressive Pediatric Cancer by Alejandra M. Scursoni, Laura Galluzzo, Sandra Camarero, Jessica Lopez, Fabiana Lubieniecki, Claudia Sampor, Valeria I. Segatori, Mariano R. Gabri, Daniel F. Alonso, Guillermo Chantada, María Teresa G. de Dávila

“…The N-glycolylated ganglioside NeuGc-GM3 has been described in solid tumors such as breast carcinoma, nonsmall cell lung cancer, and melanoma, but is usually not detected in normal human cells. Our aim was to evaluate the presence of NeuGc-GM3 in pediatric neuroectodermal tumors by immunohistochemistry. …”
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