Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization by Ruofei Zhang, Yanfang Shen, Xiaoying Zhou, Jianru Li, Hanqing Zhao, Zixia Zhang, Jun Zhao, Hongjun Jin, Shuanshuan Guo, Hui Ding, Guohui Nie, Zhe Zhang, Ying Wang, Xiyun Yan, Kelong Fan

“…Here, we identify transferrin receptor 1 (TfR1) as an upregulated target in NPC, with its expression levels positively correlated with hypoxia. Human heavy-chain ferritin, a specific ligand of TfR1, selectively recognizes hypoxic NPC lesions in preclinical models. …”
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Immunopathogenesis of inflammatory bowel diseases by Ye. A. Konovich, I. L. Khalif, M. V. Shapina

“…Investigations of experimental enterocolites and human IBD confirm immunologic hypothesis of pathogenesis: relation of their development to defects of innate and adaptive immune system.…”
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MENTAL BARRIERS TO REDUCE VULNERABILITY TO INJURY DURING A FALL: AN ELEMENTARY ISSUE OF PERSONAL SAFETY IN A GLOBAL CIVILIZATION by Bartłomiej Gąsienica-Walczak, Artur Kalina, Artur Litwiniuk, Joanna Baj-Korpak

“…The effects of unintentional human falls are seen as a serious public health problem. …”
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The Impact of Bioactive Lipids on Cardiovascular Development by Alexander Kleger, Stefan Liebau, Qiong Lin, Götz von Wichert, Thomas Seufferlein

“…Interestingly, S1P may also act to maintain human stem cell pluripotency. …”
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Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages by Susu M. Zughaier, Brandon B. Stauffer, Nael A. McCarty

“…This is the first report to show that inflammation and ER stress downregulate the expression of BDH2 in human THP-1 macrophages.…”
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Cytochrome P450 Metabolism of Betel Quid-Derived Compounds: Implications for the Development of Prevention Strategies for Oral and Pharyngeal Cancers by Che-Yi Lin, Tien-Szu Pan, Chun-Chan Ting, Shih-Shin Liang, Shu-Hung Huang, Hsiu-Yueh Liu, Edward Cheng-Chuan Ko, Chung-Wei Wu, Jen-Yang Tang, Ping-Ho Chen

“…Betel quid (BQ) products, with or without tobacco, have been classified by the International Agency for Research on Cancer (IARC) as group I human carcinogens that are associated with an elevated risk of oral potentially malignant disorders (OPMDs) and cancers of the oral cavity and pharynx. …”
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The Impact of Land Development Rights Transfer on Urban–Rural Spatial Justice: A Case Study of Chongqing’s Land Quota Trading by Siyi Wei, Jing Huang, Zhanlu Zhang

“…Spatial justice, as a fundamental value in social systems, plays a key role in achieving social justice and improving human well-being. Drawing on theories of spatial justice, property rights, and new institutional economics, this study explores the comprehensive impact of land development rights (LDR) transfer on urban–rural spatial economic, resources, social, and ecological equity from the perspective of urban–rural spatial justice. …”
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Potentials of Curcumin as an Antidepressant by S.K. Kulkarni, Ashish Dhir, Kiran Kumar Akula

“…Major depression, a debilitating psychiatric disorder, is predicted to be the second most prevalent human illness by the year 2020. Various antidepressants, ranging from monoamine oxidase inhibitors to recently developed dual reuptake inhibitors, are prescribed for alleviating the symptoms of depression. …”
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Quantitative Analysis of the Proteome and the Succinylome in the Thyroid Tissue of High-Fat Diet-Induced Hypothyroxinemia in Rats by Baoxiang Hu, Meng Zhao, Dandan Luo, Chunxiao Yu, Shanshan Shao, Lifang Zhao, Yashuang Yang, Xiaohan Zhang, Jiajun Zhao, Ling Gao

“…Finally, the mitochondrial oxygen consumption rates of human normal thyroid epithelial cells were measured to further verify the role of lysine succinylation. …”
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Green Space Planning and Landscape Sustainable Design in Smart Cities considering Public Green Space Demands of Different Formats by Juan Shan, Zhuo Huang, Sibo Chen, Yue Li, Wenli Ji

“…Smart UGS planning is a technical management tool and a human-centered smart application. A novel UGS classification method based on function combinations is proposed in the present work. …”
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Complementary feeding and the early origins of obesity risk: a study protocol by Daniel D Reidpath, Ireneous N Soyiri, Naleena Devi Muniandy, Pascale A Allotey

“…For the qualitative strand, selected mothers will be interviewed to explore their infant feeding practices and factors that influence their practices and food choices in detail.Ethics and dissemination Ethical clearance for this study was sought through the Monash University Human Research and Ethics Committee (application number CF14/3850-2014002010). …”
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Use of Magnetic Nanoparticles as Targeted Therapy: Theranostic Approach to Treat and Diagnose Cancer by Arif Malik, Tariq Tahir Butt, Sara Zahid, Fatima Zahid, Sulayman Waquar, Mahmood Rasool, Mahmood Husain Qazi, Aamer Mahmood Qazi

“…To overcome the uncontrolled growth of the proliferating cells, nanosystems have been developed and have undergone many preclinical trials both in vitro and in vivo and many practices have been further applied clinically on human beings. In practice, magnetic nanoparticles- (MNPs-) based systems following the application of Fe3O4 bound antitumor drug have shown an enhanced therapeutic index in comparison with conventional chemotherapy ensuring the significant decline in nanosystems’ toxicity. …”
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Developing the Preventing Model of Transnational Crimes in Russia and Indonesia in the Age of Sanctions and Global Economic Instability by Toebagus Galang Windi Pratama, Ruslan Puzikov, Sergey Lantsov, Vadim Ponkratov, Ekaterina Khomenko, Larisa Vatutina, Gustavo Henrique Rodrigues Pessoa

“…This study reveals novel insights into the distinct patterns of transnational crime: Russia primarily faces cybercrime, economic offenses, and money laundering, while Indonesia grapples with human trafficking, environmental crimes, and maritime piracy. …”
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Towards a Vaccine Against Rheumatic Fever by L. Guilherme, K. C. Faé, F. Higa, L. Chaves, S. E. Oshiro, S. Freschi de Barros, C. Puschel, M. A. Juliano, A. C. Tanaka, G. Spina, J. Kalil

“…We have focused on the search for protective T and B cell epitopes by testing 620 human blood samples against overlapping peptides spanning 99 residues of the C-terminal portion of the M protein, differing by one amino acid residue. …”
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A Comparative Phytochemical Investigation of the Greek Members of the Genus <i>Helichrysum</i> Mill., with Emphasis on the Local Endemic <i>Helichrysum amorginum</i> Boiss and Orph by Iordanis Samanidis, Nikos Krigas, Vassilis Athanasiadis, Ioannis Makrygiannis, Martha Mantiniotou, Stavros I. Lalas

“…Their importance is recognized as several species hold significant ethnopharmacological value, being traditionally used to address ailments in human systems, such as respiratory, gastrointestinal, and urinary conditions, among others. …”
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Enhancing Mixed Traffic Flow Safety via Connected and Autonomous Vehicle Trajectory Planning with a Reinforcement Learning Approach by Yanqiu Cheng, Chenxi Chen, Xianbiao Hu, Kuanmin Chen, Qing Tang, Yang Song

“…The safety impact of CAV trajectory planning to the mixed traffic flow with both CAV and human-driven vehicle (HDV), however, is not well understood yet. …”
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Protection Effect of Endomorphins on Advanced Glycation End Products Induced Injury in Endothelial Cells by Jing Liu, Liping Yan, Ruilan Niu, Limin Tian, Qi Zhang, Jinxing Quan, Hua Liu, Suhong Wei, Qian Guo

“…This study is to investigate the effects of EMs on the synthesis and secretion of vasoactive substances induced by advanced glycation end products in primary cultured human umbilical vein endothelial cells (HUVECs). …”
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Transmitted Drug Resistance among People Living with HIV/Aids at Major Cities of Sao Paulo State, Brazil by Joao Leandro Paula Ferreira, Rosangela Rodrigues, Andre Minhoto Lança, Valeria Correia de Almeida, Simone Queiroz Rocha, Taisa Grotta Ragazzo, Denise Lotufo Estevam, Luis Fernando de Macedo Brigido

“…Human immunodeficiency virus type 1 (HIV-1) transmitted drug resistance (TDR) is an important public health issue. …”
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Partly cloudy with a chance of mosquitoes: Developing a flexible approach to forecasting mosquito populations by Travis McDevitt‐Galles, Arthur T. Degaetano, Sarah C. Elmendorf, John R. Foster, Howard S. Ginsberg, Mevin B. Hooten, Shannon LaDeau, Katherine M. McClure, Sara Paull, Erin Posthumus, Ilia Rochlin, Daniel Grear

“…Abstract Climate‐induced shifts in mosquito phenology and population structure have important implications for the health of humans and wildlife. The timing and intensity of mosquito interactions with infected and susceptible hosts are a primary determinant of vector‐borne disease dynamics. …”
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Social communication networks and videoconferencing by Ian Saunderson, Gideon de Wet

“…The nature of social networks reveals that it will always be in existence where human interaction is present. However, communication management strategies are indeed required to ensure that the quality of information disseminated over the social network contributes to sound managerial outcomes. …”
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