Drug Target Identification and Elucidation of Natural Inhibitors for : An Study by Surya Narayan Rath, Manisha Ray, Animesh Pattnaik, Sukanta Kumar Pradhan

“…Environmental microbes like Bordetella petrii has been established as a causative agent for various infectious diseases in human. Again, development of drug resistance in B. petrii challenged to combat against the infection. …”
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Nuclear Position and Shape Deformation of Chromosome 8 Territories in Pancreatic Ductal Adenocarcinoma by Sylvia Timme, Eberhard Schmitt, Stefan Stein, Jutta Schwarz-Finsterle, Jenny Wagner, Axel Walch, Martin Werner, Michael Hausmann, Thorsten Wiech

“…Cell type specific radial positioning of chromosome territories (CTs) and their sub-domains in the interphase seem to have functional relevance in non-neoplastic human nuclei, while much less is known about nuclear architecture in carcinoma cells and its development during tumor progression. …”
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Hyaluronate Acid-Dependent Protection and Enhanced Corneal Wound Healing against Oxidative Damage in Corneal Epithelial Cells by Jing Zhong, Yuqing Deng, Bishan Tian, Bowen Wang, Yifang Sun, Haixiang Huang, Ling Chen, Shiqi Ling, Jin Yuan

“…To evaluate the effects and mechanism of exogenous hyaluronate (HA) in promoting corneal wound healing. Methods. Human corneal epithelial cells (HCECs) were incubated with different concentrations of HA to evaluate their efficiency in promoting cell migration and their modulation of repair factors. …”
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Multiparametric Ultrasound (mpUS) of a Rare Testicular Capillary Hemangioma by Paul Spiesecke, Thomas Fischer, Carsten Stephan, Andreas Maxeiner, Bernd Hamm, Markus Lerchbaumer

“…We demonstrate the case of an 18-year-old patient with palpatoric and sonographic conspicuous left testicle and negative serum tumor markers (α-fetoprotein, β-human chorionic gonadotropin, and lactate dehydrogenase). …”
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Design and Evaluation of a Leader–Follower Isomorphic Vascular Interventional Surgical Robot by Pengfei Chen, Yutang Wang, Dapeng Tian

“…The leader–follower delivery error of the catheter/guidewire is less than 1 mm, and the leader–follower rotation error of the guidewire is less than 0.3° in an actual intervention task based on a human vascular model. Subsequently, the cumulative sum (CUSUM) method was used to evaluate the learning curve of the robot system, demonstrating that both operators could master the operation method within 10 trials. …”
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Vegetation Activity Trend and Its Relationship with Climate Change in the Three Gorges Area, China by Guifeng Han, Yongchuan Yang, Shuiyu Yan

“…In addition, resettlement schemes mitigate the impact of human activity on vegetation activity.…”
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Pharmacokinetic and Biodistribution Assessment of a Near Infrared-Labeled PSMA-Specific Small Molecule in Tumor-Bearing Mice by Joy L. Kovar, Lael L. Cheung, Melanie A. Simpson, D. Michael Olive

“…IRDye 800CW was conjugated to YC-27 or an anti-PSMA antibody used for reference. Human 22Rv1, PC3M-LN4, and/or LNCaP prostate tumor cells were exposed to the labeled compounds. …”
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Molecular Epidemiology of Enteric Adenovirus Gastroenteritis in under-Five-Year-Old Children in Iran by Anahita Sanaei Dashti, Pedram Ghahremani, Tayebeh Hashempoor, Abdollah Karimi

“…The aim of this study was to determine the prevalence of human adenovirus- (HAdV-) 40 and HAdV-41 in children hospitalized with gastroenteritis in five different health centers of Iran. …”
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Welfare of horses at slaughter by EFSA Panel on Animal Health and Welfare (AHAW), Søren Saxmose Nielsen, Julio Alvarez, Anette Boklund, Sabine Dippel, Fernanda Dorea, Jordi Figuerola, Mette Herskin, Miguel Angel Miranda Chueca, Eleonora Nannoni, Romolo Nonno, Anja Riber, Karl Stahl, Jan Arend Stegeman, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Mohan Raj, Antonio Velarde, Denise Candiani, Yves Van der Stede, Virginie Michel

“…Abstract The objective of this Scientific Opinion is to assess the hazards and welfare consequences associated with the slaughter of horses for human consumption. The entire slaughter procedure, from arrival at the slaughterhouse until death, is divided into three phases: Phase 1 – pre‐stunning, Phase 2 – stunning and Phase 3 – bleeding. …”
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The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling by Liusong Yin, Xiaoying Chen, Abhinav Tiwari, Paolo Vicini, Timothy P. Hickling

“…Therapeutic protein products (TPP) have been widely used to treat a variety of human diseases, including cancer, hemophilia, and autoimmune diseases. …”
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Coupling between topological edge state and defect mode-based biosensor using phononic crystal by Zaky A. Zaky, M. Al-Dossari, Ahmed S. Hendy, Yassine Bouazzi, Attia Boudjemline, Arafa H. Aly

“…Abstract A wealth of details regarding an individual’s state of health, like a person’s respiratory and metabolic functioning, can be studied by analyzing the volatile molecules and atoms in human exhaled breath. Besides, the salinity of seawater is a crucial factor in understanding its characteristics because any variation in the salinity of seawater represents the variations in the hydrological, biological, and chemical distributions. …”
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Bringing Motor Imagery BCI systems outside of the laboratory into daily activities by Sonal Santosh Baberwal, Shirley Coyle

“…Furthermore, integrating soft robotics as intuitive control interfaces for performing daily activities, such as pressing spray buttons, exemplifies potential for seamless human-machine interaction. By advancing training protocols, reducing complexity, and enhancing usability, this work brings MI-BCIs closer to real-world applications. …”
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Production of an Extract with β-1,4-Xylanase Activity by <i>Fusarium oxysporum</i> f. sp. <i>melonis</i> on a Sonicated Brewer’s Spent Grain Substrate by Irma A. Arreola-Cruz, Rosalba Troncoso-Rojas, Francisco Vásquez-Lara, Nina G. Heredia-Sandoval, Alma R. Islas-Rubio

“…The <i>Fusarium oxysporum</i> species commonly found in soil include plant and human pathogens, and nonpathogenic species. <i>F. oxysporum</i> grown on lignocellulosic substrates under submerged conditions produces an extracellular enzyme profile with hemicellulolytic and cellulolytic activities. …”
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Symptom Status Predicts Patient Outcomes in Persons with HIV and Comorbid Liver Disease by Wendy A. Henderson, Angela C. Martino, Noriko Kitamura, Kevin H. Kim, Judith A. Erlen

“…Persons living with human immunodeficiency virus (HIV) are living longer; therefore, they are more likely to suffer significant morbidity due to potentially treatable liver diseases. …”
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Atomic Force Microscopy (AFM) nanomechanical characterization of micro- and nanoplastics to support environmental investigations in groundwater by Massimiliano Galluzzi, Michele Lancia, Chunmiao Zheng, Viviana Re, Valter Castelvetro, Shifeng Guo, Stefano Viaroli

“…Micro and nanoplastic (MNP) pollution is a severe environmental issue, posing potential risks to environmental and human health due to the intrinsic toxicity of plastic particles and their capacity to adsorb other pollutants. …”
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Sargassum plagiophyllum Ethanolic Extract Enhances Wound Healing by Modulating FAK/Src/Akt/p38 and Rac1 Signaling in Keratinocytes HaCaT Cells by Furoida Moolsup, Wanida Sukketsiri, Wipawadee Sianglum, Jirawat Saetan, Nattakanwadee Khumpirapang, Supita Tanasawet

“…This study, therefore, aimed to explore phytochemical analysis, antimicrobial, antioxidant, and wound healing properties of brown seaweed Sargassum plagiophyllym ethanolic extract (SPEE) on human skin keratinocyte HaCaT cells and the possible mechanism involved. …”
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Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death by Jialin Dai, Jiangjin Liu, Qiong Zhang, Yang An, Bing Xia, Changwu Wan, Yuanyuan Zhang, Yanni Yu, Jie Wang

“…It provides a proteomic analysis of human left anterior descending coronary artery from subjects diagnosed with SCD through histological examination and cases of nondisease accidental deaths through autopsy. …”
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Intelligent methods for natural data analysis: application to space weather by O.V. Mandrikova

“…The negative impact of space weather anomalies on human health and practically all modern infrastructure objects requires the development of methods and the creation of effective means of detecting anomalies. …”
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Adolescents: Contraceptive Knowledge and Use, a Brazilian Study by Divanise S. Correia, Ana C. P. Pontes, Jairo C. Cavalcante, E. Sócrates T. Egito, Eulália M.C. Maia

“…This study was approved by the Human Research Ethics Committee, and Epi InfoTM software was used for data and result evaluation using the mean and chi-square statistical test. …”
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Investigation of Air Quality and the Effects of Meteorological Factors on Air Pollution in Nevşehir Province by Kahraman Oğuz

“…Increasing urban air pollution causes important problems affecting the environment and human health. One of the most important sources of urban air pollution is the road transport sector. …”
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