Dystrophic Adipocytes Mimicking Metastatic Signet Ring Cell Adenocarcinoma: A Diagnostic Pitfall in a Cachectic Patient by Xin Zhang, Jennifer J. Findeis-Hosey

“…While pathological changes of cachectic conditions on adipose tissue have been studied and documented in tumor-bearing animal models, similar morphological changes in human surgical specimens are rare. Here we report a case of a cachectic patient with pancreatic adenocarcinoma whose adipocytes underwent dramatic lipodystrophy mimicking signet ring cell adenocarcinoma. …”
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Targeting glycolytic reprogramming by tsRNA-0032 for treating pathological lymphangiogenesis by Fan Ye, Ziran Zhang, Lianjun Shi, Shuting Lu, Xiumiao Li, Wan Mu, Qin Jiang, Biao Yan

“…In this study, we elucidate the role of tsRNA-0032 in lymphangiogenesis and its molecular mechanism. tsRNA-0032 expression is significantly decreased in corneal suture model and human lymphatic endothelial cell (HLEC) model under inflammatory condition. …”
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EEG analysis of speaking and quiet states during different emotional music stimuli by Xianwei Lin, Xinyue Wu, Zefeng Wang, Zhengting Cai, Zihan Zhang, Guangdong Xie, Lianxin Hu, Laurent Peyrodie

“…IntroductionMusic has a profound impact on human emotions, capable of eliciting a wide range of emotional responses, a phenomenon that has been effectively harnessed in the field of music therapy. …”
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Identifying Candidate Genes for Type 2 Diabetes Mellitus and Obesity through Gene Expression Profiling in Multiple Tissues or Cells by Junhui Chen, Yuhuan Meng, Jinghui Zhou, Min Zhuo, Fei Ling, Yu Zhang, Hongli Du, Xiaoning Wang

“…In the current study, gene expression levels in multiple human tissues from GEO datasets were analyzed, and 21 candidate genes displaying high percentages of differential expression were filtered out. …”
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Anti-cancer effect of midazolam via downregulating YWHAH in papillary thyroid cancer cells by Yang Li, Ai-Ping Tan, Yu-Shan Zhong

“…Cell viability was detected by CCK-8 method when treated by varying doses of midazolam to detect the cytotoxicity of midazolam on human thyroid follicular epithelial cell line and thyroid cancer cell lines. …”
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Perspectives in Molecular Imaging Using Staging Biomarkers and Immunotherapies in Alzheimer’s Disease by Benoît Leclerc, Abedelnasser Abulrob

“…The complex molecular mechanisms of AD not only are supported by cholinergic, beta-amyloid, and tau theories but also have a genetic basis that accounts for the difference in symptomatology processes activation among human population which will evolve into divergent neuropathological features underlying cognitive and behaviour alterations. …”
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Land Subsidence in the Yangtze River Delta, China Explored Using InSAR Technique From 2019 to 2021 by Hongbo Jiang, Guangcai Feng, Yuexin Wang, Zhiqiang Xiong, Hesheng Chen, Ning Li, Zeng Lin

“…The combined effects of global warming and human activities have intensified land subsidence (LS), limiting the sustainable development of economy in delta regions. …”
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Adenocarcinoma with Neuroendocrine Differentiation of the Colon Accompanying Osteoclast-Like Giant Cells by Mitsuhiro Tachibana, Tadahiro Isono, Yutaka Tsutsumi

“…The carcinoma cells were labeled focally for synaptophysin and diffusely for the DR locus of the human leukocyte antigen and programmed death-ligand 1 (PD-L1). …”
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Government crisis communication tools in the light of the extreme drought of 2022 by Ágnes Kovács, Edina Kriskó, Tamás Pálvölgyi, László Balatonyi

“…Value: Due to the acceleration of the hydrological cycle, it is likely that in the future humanity will have to prepare for more intense periods of extreme water scarcity. …”
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Transcutaneous Intraluminal Impedance Measurement for Minimally Invasive Monitoring of Gastric Motility: Validation in Acute Canine Models by Michael D. Poscente, Gang Wang, Dobromir Filip, Polya Ninova, Gregory Muench, Orly Yadid-Pecht, Martin P. Mintchev, Christopher N. Andrews

“…Further chronic animal studies of this novel long-term gastric motility measurement technique are needed before testing it on humans.…”
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Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran by J. Saki, N. Mohammadpour, F. Moramezi, S. Khademvatan

“…Toxoplasma gondii is an obligate intracellular protozoan parasite causing toxoplasmosis in animals and humans. Primary maternal infection with toxoplasmosis during pregnancy is frequently associated with transplacental transmission to the fetus. …”
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Can floseal™ be applied safely during otologic surgery? Assessment of ototoxicity in a chinchilla animal model by Carol Nhan, Aren Bezdjian, Abdullah Alarfaj, Sam J. Daniel

“…More studies are warranted to assess the safety and applicability of the product in humans.…”
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Developmental Changes in Sleep Oscillations during Early Childhood by Eckehard Olbrich, Thomas Rusterholz, Monique K. LeBourgeois, Peter Achermann

“…This study utilized our time-frequency method to examine sleep oscillations as characteristic features of human sleep EEG. Data were collected from a longitudinal sample of young children (n=8; 3 males) at ages 2, 3, and 5 years. …”
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Banana residue could be a viable rice straw alternative for Pleurotus mushroom production by Hend Hamed, Mohamed Mohamed, Khalid elshaikh, Maher Hosseney

“…Purpose Oyster mushroom (Pleurotus ostreatus) is becoming more popular as an efficient biotechnological procedure for upcycling agricultural by-products into valuable human food. This study looked into the possibility of employing banana residue (BR) and sorghum stalks (SS) as localized feasible rice straw (RS) substitutes for cultivating P. ostreatus. …”
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Polysaccharides of St. John’s Wort Herb Stimulate NHDF Proliferation and NEHK Differentiation via Influence on Extracellular Structures and Signal Pathways by S. Abakuks, A. M. Deters

“…Biological activity on human skin keratinocytes and fibroblasts was assessed by investigation of their effect on proliferation, metabolism, cytotoxicity, apoptosis and differentiation. …”
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Highly Sensitive Amperometric α-Ketoglutarate Biosensor Based on Reduced Graphene Oxide-Gold Nanocomposites by Gang Peng, Yadong Yu, Xiaojun Chen, He Huang

“…Moreover, the prepared GLUD/rGO-Aunano/GCE was further evaluated to be highly selective and used to test α-KG in human serum samples. The recovery and the RSD values were calculated in the range of 97.9–102.4% and 3.8–4.5%, respectively, showing a great prospect for its real application.…”
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Evaluation of Staining Reduction of Teeth Endodontically Treated with CTZ Paste through the Use of Polytetrafluoroethylene Isolation Tape by Lucas de Lima Oliveira Barbosa, Jaine Viviane Silva, Leopoldo Cosme-Silva, Daniela Maria Carvalho Pugliesi, Patrícia Batista Lopes do Nascimento, Dayse Andrade Romão, Priscylla Gonçalves Correia Leite de Marcelos, Daniel Pinto de Oliveira, Valdeci Elias dos Santos Junior

“…Material and Methods: 50 human deciduous incisors were selected. The teeth received CTZ filling and were divided according to whether or not PTFE was used, as well as by the length of the remaining root (1/3 or 2/3 of the root) and by the restorative material (Modified Resin Glass Ionomer Cement or Opus Bulk Resin Fill Flow). …”
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Evaluation of Gingival Microleakage in Class II Composite Restorations with Different Lining Techniques: An In Vitro Study by Vedavathi Bore Gowda, B. V. Sreenivasa Murthy, Swaroop Hegde, Swapna Devarasanahalli Venkataramanaswamy, Veena Suresh Pai, Rashmi Krishna

“…Forty standardized MO cavities were prepared on human permanent mandibular molars extracted for periodontal reasons and then divided into 4 groups of ten specimens. …”
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15-Lipoxygenase-1 Is Involved in the Effects of Atorvastatin on Endothelial Dysfunction by Peng Zhang, Xin Xing, Chunxiao Hu, Hui Yu, Qian Dong, Guanglei Chang, Shu Qin, Jian Liu, Dongying Zhang

“…Immunohistochemistry and western blotting showed that atorvastatin increased the expression of cellular adhesion molecules (CAMs) but decreased the expression of endothelial nitric oxide synthase (eNOS); these effects of atorvastatin were blocked by ALOX15 overexpression. In human umbilical venous endothelial cells (HUVECs), silencing of ALOX15 enhanced the effects of atorvastatin on endothelial function. …”
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Cysteinyl Leukotriene Receptor-1 Antagonists as Modulators of Innate Immune Cell Function by A. J. Theron, H. C. Steel, G. R. Tintinger, C. M. Gravett, R. Anderson, C. Feldman

“…These and other secondary anti-inflammatory mechanisms of the commonly used cysLTR1 antagonists are the major focus of the current review, which also includes a comparison of the anti-inflammatory effects of montelukast, pranlukast, and zafirlukast on human neutrophils in vitro, as well as an overview of both the current clinical applications of these agents and potential future applications based on preclinical and early clinical studies.…”
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