Screening of Insertion Sites and Tags on EV-A71 VP1 Protein for Recombinant Virus Construction by Miaomiao Kang, Xiangyi Li, Xiaohong Li, Rui Yu, Shuo Zhang, Jingjing Yan, Xiaoyan Zhang, Jianqing Xu, Buyong Ma, Shuye Zhang

“…This study aimed to create a new recombinant virus by modifying the EV-A71 capsid protein, serving as a useful tool and model for studying human Enteroviruses. We developed a new screening method using EV-A71 pseudovirus particles to systematically identify suitable insertion sites and tag types in the VP1 capsid protein. …”
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Development of a Novel Sensor System Based on Magnetic Microspheres to Detect Cardiac Troponin T by Junrong Zhang, Hongxiang Liu, Baofeng Xu, Sijun Huang, Rui Liu, Jinming Zhu, Yi Guo, Li Xu

“…The present study is aimed at exploring a novel sensing system with high specificity and precision based on magnetic microspheres developed to detect cardiac troponin T (cTnT), which is the most specific diagnostic marker for AMI in cardiovascular diseases. Naive human cTnT protein in serum samples and antigens on functional magnetic microspheres will competitively bind with limited specific antibodies. …”
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Diagnosis of planktonic trophic network dynamics with sharp qualitative changes by Gaucherel, Cedric, Fayolle, Stolian, Savelli, Raphael, Philippine, Olivier, Pommereau, Franck, Dupuy, Christine

“…These topological changes, as opposed to a dynamic on a static (frozen) network, can be triggered by natural forcings (e.g., seasons) and/or by human influences (e.g., nutrient or pollution inputs). …”
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Graphene-Based, Flexible, Wearable Piezoresistive Sensors with High Sensitivity for Tiny Pressure Detection by Rui Li, Jiahao Hu, Yalong Li, Yi Huang, Lin Wang, Mohan Huang, Zhikun Wang, Junlang Chen, Yan Fan, Liang Chen

“…The piezoresistive performance converts subtle laryngeal articulatory vibration into a stable, regular electrical signal; in addition, there is excellent real-time monitoring capability of human joint movements. This work provides a new idea for the development of wearable electronic devices, healthcare, and other fields.…”
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The effect of AKT inhibition in α-synuclein-dependent neurodegeneration by Bedri Ranxhi, Zoya R. Bangash, Zachary M. Chbihi, Sokol V. Todi, Sokol V. Todi, Peter A. LeWitt, Peter A. LeWitt, Peter A. LeWitt, Wei-Ling Tsou

“…We observed that administration of the AKT inhibitor, A-443654 led to mild improvements in both survival and motor function in flies expressing human α-Syn. Genetic studies revealed that reduction of AKT levels decreased α-Syn protein levels, concomitant with improved physiological outcomes. …”
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The semi-wild mariculture of Caribbean King Crab (Maguimithrax spinosissimus) for coral reef restoration by Samantha Glover, Mark J. Butler, IV

“…Aquaculture has traditionally focused on supporting human food production, but there is a growing need for aquaculture associated with environmental restoration. …”
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Sensitive and label-free fluorescent microRNA detection via catalytic DNAzyme assembly initiated primer exchange reaction by Heng Wang, Yi Sun

“…MicroRNAs (miRNAs) have an intricate connection to the development of human diseases, such as malignancies, diabetes, and viral infections; therefore, their rapid and precise identification is critical in disease diagnosis and treatment. …”
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3D Imaging of Dead Sea Area Using Weighted Multipath Summation: A Case Study by Shemer Keydar, Benjamin Medvedev, Abdallah Al-Zoubi, Michael Ezersky, Emad Akkawi

“…The formation of sinkholes along the Dead Sea is caused by the rapid decline of the Dead Sea level, as a possible result of human extensive activity. According to one of the geological models, the sinkholes in several sites are clustered along a narrow coastal strip developing along lineaments representing faults in NNW direction. …”
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The Role of Architectural Preservation Processes on the Permanence of Heritage Buildings of Value by Sham Mustafa Qadir, Banaz N. Muhealdeen, Mahmood Ahmed Khayat, Sherko Karim Kader Maruf, Shava Shirwan Ibrahim Agha

“…The architectural heritage has been exposed to natural and human factors that caused much damage. This requests to deal with these factors at every level through joint action, which includes the maintenance and protection of heritage buildings. …”
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Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review by Linda Tong Pao, Mohamed Tashani, Catherine King, Harunor Rashid, Ameneh Khatami

“…There appears to be an association between attendance at mass gatherings and the acquisition of some AMR phenotypes and genotypes in some significant human pathogens, including <i>E. coli</i> and <i>S. pneumoniae</i>.…”
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Analysis of Rainfall Trends and Its Relationship with SST Signals in the Lake Tana Basin, Ethiopia by Tesfay Mekonnen Weldegerima, Tadesse Terefe Zeleke, Belay Simane Birhanu, Benjamin Frederick Zaitchik, Zewdu Alamineh Fetene

“…The impacts of climate change and climate variability on human life have led the scientific community to monitor the behavior of weather and climate variables at different spatial and temporal scales. …”
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Forecasting O3 and NO2 concentrations with spatiotemporally continuous coverage in southeastern China using a Machine learning approach by Zeyue Li, Jianzhao Bi, Yang Liu, Xuefei Hu

“…The presence of O3 and NO2 has detrimental effects on human health, the ecosystem, and agricultural production. …”
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Electrodeposition of 4-Benzenesulfonic Acid onto a Graphite-Epoxy Composite Electrode for the Enhanced Voltammetric Determination of Caffeine in Beverages by Leonardo de A. Furtado, Mariana C. de O. Gonçalves, Carlos V. M. Inocêncio, Edilson M. Pinto, Daniela de L. Martins, Felipe S. Semaan

“…Caffeine is widely present in food and drinks, such as teas and coffees, being also part of some currently commercialized medicines, but despite its enhancement on several functions of human body, its exceeding use can promote many health problems. …”
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Reduced UPF1 levels in senescence impair nonsense-mediated mRNA decay by Dahyeon Koh, Yebin Lee, Kyuchan Kim, Hyeong Bin Jeon, Chaehwan Oh, Sangik Hwang, Minjung Lim, Kwang-Pyo Lee, Yeonkyoung Park, Yong Ryoul Yang, Yoon Ki Kim, Donghwan Shim, Myriam Gorospe, Ji Heon Noh, Kyoung Mi Kim

“…While the role of NMD in cancer and developmental and genetic diseases is well documented, its implications in human aging remain largely unexplored. This study reveals a significant decline in the levels of the protein UPF1, a key player in NMD, during cellular senescence. …”
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THE EFFECT OF TRANSACTIONAL LEADERSHIP ON EMPLOYEES PERFORMANCE – CASE STUDY OF 5 ALGERIAN BANKING INSTITUTIONS by Ali Bousbia Brahim, Ognjen Riđić, Tomislav Jukić

“…The research was conducted to see how efficiently and effectively managers used available human and other material and financial resources to satisfy customers and achieve organizational goals. …”
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Analysis of factors affecting the evolution of the sign system and the duality of identity in the urban context with a semiotic approach by azadeh atashpanjeh, mohammad naghizadeh, Zahrasadat saeideh zarabadi

“…Studies in the old context relied heavily on documents and in the new context is field and the samples were studied in hot and dry areas of Iran.The results show that based on the study of representations in the symbolic system in the textual layers of the city form, the duality of meaning and identity of the old and new textures of a city over time indicate several main factors of change within the textual layers of the form of city, the rupture and duality in the human layer and change in the system of codes that affect the structure of the city form, which is manifested in the elimination, replacement or change of signs in the natural, social and artificial layers.…”
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Simple assay quantifying sediment resuspension effects on marine carbon storage by Ines Bartl, Tegan Evans, Jenny Hillman, Simon Thrush

“…Abstract The seafloor plays a vital role in Earth's climate by storing carbon. However, human activities that disturb the seafloor undermine this function and receive little regulatory attention. …”
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Complex Probiotics Suppress Inflammation by Regulating Intestinal Metabolites in Kittens by Shimin Zhu, Musu Zha, Yanan Xia

“…Cats are popular companions for humans, and their health is of importance to a growing number of pet owners. …”
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Regulatory Role of GSK-3β on NF-κB, Nitric Oxide, and TNF-α in Group A Streptococcal Infection by Yu-Tzu Chang, Chia-Ling Chen, Chiou-Feng Lin, Shiou-Ling Lu, Miao-Huei Cheng, Chih-Feng Kuo, Yee-Shin Lin

“…Group A streptococcus (GAS) imposes a great burden on humans. Efforts to minimize the associated morbidity and mortality represent a critical issue. …”
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Utility of complexity analysis in electroencephalography and electromyography for automated classification of sleep-wake states in mice by Naoki Furutani, Yuki C. Saito, Yasutaka Niwa, Yu Katsuyama, Yuta Nariya, Mitsuru Kikuchi, Tetsuya Takahashi, Takeshi Sakurai

“…This integrated model significantly enhances the accuracy of sleep stage identification, achieving an accuracy of 97.4–98.1% for novel wild-type mice, on par with the agreement level among human scorers (97.3–97.8%). The efficacy of SAC was validated through tests conducted on wild-type mice, and it demonstrated remarkable success in identifying sleep architecture abnormalities in narcoleptic mice as well. …”
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