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17481
Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer
Published 2018-01-01“…Thus, it is unsurprising that alteration of protein acetylation is involved in human disease, including metabolic disorders and cancers. …”
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17482
Harmonising careers: opera, hospitality and tourism industries unite to elevate graduate students employability
Published 2025-12-01“…Drawing on Social Exchange and Human Capital Theories, it showcases how this model enhances employability, bestowing graduates with a unique fusion of artistic flair and practical hospitality expertise. …”
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17483
Diagnosis dan Penatalaksanaan Papiloma Laring Berulang pada Dewasa
Published 2018-10-01“…Pendahuluan: Papiloma laring merupakan tumor yang berasal dari infeksi Human Papiloma Virus (HPV) yang bersifat jinak, berulang dan berisiko berubah menjadi ganas. …”
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17484
Manufacturing high-performance flexible sensors via advanced patterning techniques
Published 2025-01-01“…Sensors play an important role in information perception during the age of intelligence, particularly in areas such as environmental monitoring and human perception. To meet the huge demands for information acquisition in the whole society, the development of elaborated sensor structures using patterned manufacturing technology is important to improve the performance of sensors. …”
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17485
Comparative Analysis of Traditional and Modern NLP Techniques on the CoLA Dataset: From POS Tagging to Large Language Models
Published 2025-01-01“…These challenges include distinguishing between subtle grammatical errors, understanding complex syntactic structures, and detecting semantic inconsistencies, all of which make the task difficult even for human annotators. In this article, we compare a range of techniques, from traditional methods such as Part-of-Speech (POS) tagging and feature extraction methods like CountVectorizer with Term Frequency-Inverse Document Frequency (TF-IDF) and N-grams, to modern embeddings such as FastText and Embeddings from Language Models (ELMo), as well as deep learning architectures like transformers and Large Language Models (LLMs). …”
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17486
On Facial Expression Recognition Benchmarks
Published 2021-01-01“…Facial expression is an important form of nonverbal communication, as it is noted that 55% of what humans communicate is expressed in facial expressions. …”
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17487
Allogeneic Antigen Composition for Preparing Universal Cancer Vaccines
Published 2016-01-01“…Recently it was demonstrated that tumors induce specific changes to the surface of human endothelial cells thereby providing the basis for designing endothelial cell-based vaccines that directly target antigens expressed by the tumor endothelium. …”
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17488
Microenvironment-confined kinetic elucidation and implementation of a DNA nano-phage with a shielded internal computing layer
Published 2025-01-01“…Finally, we show that DNP can efficiently work in complex human blood samples by shielding the interference of erythrocytes and enhance phagocytosis of macrophages toward target cells by blocking CD47-SIRPα pathway.…”
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17489
Exploring the maternal inheritance transmitted by the oocyte to its progeny
Published 2024-06-01“…Organisms that propagate via sexual reproduction often come from the fusion between two gametes, an oocyte and a sperm, whose qualities seem to be decreasing in the human species. Interestingly, while the sperm mostly transmits its haploid genome, the oocyte transmits not only its haploid set of chromosomes but also its huge cytoplasm to its progeny. …”
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17490
Inferring single-cell and spatial microRNA activity from transcriptomics data
Published 2025-01-01“…Abstract The activity of miRNA varies across different cell populations and systems, as part of the mechanisms that distinguish cell types and roles in living organisms and in human health and disease. Typically, miRNA regulation drives changes in the composition and levels of protein-coding RNA and of lncRNA, with targets being down-regulated when miRNAs are active. …”
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17491
Phospholipogenic Pharmaceuticals Are Associated with a Higher Incidence of Histological Findings than Nonphospholipogenic Pharmaceuticals in Preclinical Toxicology Studies
Published 2012-01-01“…While phospholipidosis is thought to be an adaptive response to chemical challenge, many phospholipogenic compounds are known to display adverse effects in preclinical species and humans. To investigate the link between phospholipogenic administration and incidence of preclinical histological signals, an internal AstraZeneca in vivo toxicology report database was searched to identify phospholipogenic and nonphospholipogenic compounds. …”
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17492
Promoting HOTS and critical thinking to English students of higher education through authentic assessment
Published 2022-05-01“…The development of social life relationship in this 21st century becomes more challenging than the previous era. All the human being needs to be designed sophisticatedly with some skills to maintain the global welfare, such as critical thinking skill which is the ability to test, analyze and explain the validity of the information according to a particular task or situation. …”
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17493
Evaluation of Oxidative Stress and Mitophagy during Adipogenic Differentiation of Adipose-Derived Stem Cells Isolated from Equine Metabolic Syndrome (EMS) Horses
Published 2018-01-01“…Mesenchymal stem cells (MSCs) are frequently used in both human and veterinary medicine because their unique properties, such as modulating the immune response and differentiating into multiple lineages, make them a valuable tool in cell-based therapies. …”
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17494
Therapeutic Targeting of Fibroblast Growth Factor Receptors in Gastric Cancer
Published 2015-01-01“…Many molecular-targeted therapies inhibiting signaling pathways of various tyrosine kinase receptors have been developed, and monoclonal antibodies targeting human epidermal growth factor receptor 2 (HER2) have become standard therapy for HER2-positive GC. …”
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17495
INTERNATIONAL CHARITABLE ORGANIZATIONS: ESTABLISHMENT, DEVELOPMENT AND FEATURES OF FUNCTIONING
Published 2024-12-01“…With the help of an interdisciplinary approach, it was possible to identify the historical background of the origin of the phenomenon of selfless human activity, a systematic political and legal analysis of international and domestic legislation helped to identify the peculiarities of the functioning of international charitable organizations in the United States, Europe and Ukraine, and a generalization of the obtained results crystallized the foundations and features of their direct involvement in problem areas. …”
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17496
An atlas of metabolites driving chemotaxis in prokaryotes
Published 2025-02-01“…Our analysis reveals that (i) not all chemical classes trigger chemotaxis equally, in particular, amino acids and benzenoids are much stronger attractants than carbohydrates; (ii) over one-quarter of attractants tested are not used for growth but solely act as chemotactic signals; (iii) the prokaryote’s origin matters, as terrestrial strains respond to 50% more chemicals than those originating from human or marine biomes; (iv) repellents affect cell behaviour at concentrations 10-fold higher than attractants; (v) the effect of large molecules and the behaviour of bacteria other than Proteobacteria have been largely overlooked. …”
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17497
Integrating Sustainable HRM, AI, and Employee Well-Being to Enhance Engagement in Greater Jakarta: An SDG 3 Perspective
Published 2025-01-01“…This study explores a combination of Sustainable Human Resource Management and Artificial Intelligence on employee well-being with a view to improving employee engagement for workers in Greater Jakarta, Indonesia. …”
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17498
EVALUATION OF WORLD ENERGY SCENARIOS
Published 2016-04-01“…It remains one the biggest unknown, especially in terms of energy, as it is globally considered as both cause and solution for multiple problems of the humanity. Therefore, nowadays a number of experts are exploring driving forces, critical uncertainties and unknowns that have an influence on future energy systems development. …”
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17499
Evaluation of Randomised Controlled Trials Published in Indian Specialty Dental Journals for Statistical Testing of Baseline Differences: A Meta-Epidemiological Study
Published 2023-07-01“…Objective: This study aimed to assess the proportion of RCTs on human participants comparing the baseline differences between intervention groups using the test of significance in nine dental specialty journals published in India and to estimate the proportion of studies reporting baseline demographic and clinical characteristics in a table. …”
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17500
Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials
Published 2010-01-01“…A review of www.ClinicalTrials.gov of the United States National Institute of Health was performed, and ongoing clinical trials will be discussed in addition to the sentinel preclinical studies that paved the way for human investigations.…”
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