NF-κB Inhibitory Activity of the Di-Hydroxy Derivative of Piperlongumine (PL-18) by Yael Schlichter Kadosh, Subramani Muthuraman, Ariel Kushmaro, Rajendran Saravana Kumar, Jacob Gopas

“…NF-kB was inhibited by PL-18 in two human cell-lines, L428 and A549, by preventing the nuclear translocation of p65 NF-kB. …”
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Measuring the Complex Construct of Macroergonomic Compatibility: A Manufacturing System Case Study by Arturo Realyvásquez, Aide A. Maldonado-Macías

“…Macroergonomic compatibility (MC) refers to the extent to which macroergonomic factors and elements (MFEs) interact positively with humans. It is one of the most complex constructs to measure in work systems and in ergonomics. …”
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Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity by Dyah Ika Krisnawati, Yung-Ching Liu, Yuarn-Jang Lee, Yun-Ting Wang, Chia-Ling Chen, Po-Chun Tseng, Ting-Jing Shen, Chiou-Feng Lin

“…In the presence of patient serum, IFN-γ-induced type 1 macrophage (M1) differentiation was inhibited in PMA-stimulated human monocytic THP-1 cells. Treatment with patient serum significantly blocked the production of proinflammatory factors, including cytokines/chemokines and reactive oxygen/nitrogen species, by M1 macrophages. …”
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Dietary Cocoa Powder Improves Hyperlipidemia and Reduces Atherosclerosis in apoE Deficient Mice through the Inhibition of Hepatic Endoplasmic Reticulum Stress by Hua Guan, Yan Lin, Liang Bai, Yingfeng An, Jianan Shang, Zhao Wang, Sihai Zhao, Jianglin Fan, Enqi Liu

“…Cocoa powder is rich in flavonoids, which have many beneficial effects on human health, including antioxidative and anti-inflammatory effects. …”
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Engineering Activity and Engineering Thinking in the Context of Artificial Intelligence Expansion by V. S. Sheinbaum, V. S. Nikolskiy

“…A definition of engineering activity is proposed, which reveals its essence through its goal of solving human and societal problems. A non-instrumental approach to the interpretation of engineering based on AI technologies is substantiated, within which artificial intelligence appears as a partner in engineering activity. …”
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Synthesis, Characterization, and Biological Activity of N′-[(Z)-(3-Methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)(phenyl)methyl]benzohydrazide and Its Co(II), Ni(II), and... by Jonnie N. Asegbeloyin, Oguejiofo T. Ujam, Emmanuel C. Okafor, Ilknur Babahan, Esin Poyrazoglu Coban, Ali Özmen, Halil Biyik

“…The compounds were screened for their in vitro cytotoxic activity against HL-60 human promyelocytic leukemia cells and antimicrobial activity against some bacteria and yeasts. …”
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Water Management Practices Affect Arsenic and Cadmium Accumulation in Rice Grains by Liming Sun, Manman Zheng, Hongyan Liu, Shaobing Peng, Jianliang Huang, Kehui Cui, Lixiao Nie

“…Cadmium (Cd) and arsenic (As) accumulation in rice grains is a great threat to its productivity, grain quality, and thus human health. Pot and field studies were carried out to unravel the effect of different water management practices (aerobic, aerobic-flooded, and flooded) on Cd and As accumulation in rice grains of two different varieties. …”
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Analysis of the impact of the Covid-19 epidemic through the sojourn tax and the attitudes of the respondents by Jakovljević Nemanja

“…The impact of the global epidemic caused by the appearance and spread of the Covid19 virus has led to strong effects on all human labor activities, of which tourism stands out, as the activity most affected by the virus. …”
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Advancements in the development of antivirals against SARS-Coronavirus by Mrityunjay Kumar, Mirza Sarwar Baig, Kanchan Bhardwaj, Kanchan Bhardwaj

“…Later research showed that SARS-CoV came from animals (zoonosis) and stressed the possibility of a similar spread from host to human, which was clearly shown by the COVID-19 outbreak. …”
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A Look into Stem Cell Therapy: Exploring the Options for Treatment of Ischemic Stroke by Cesar Reis, Michael Wilkinson, Haley Reis, Onat Akyol, Vadim Gospodarev, Camila Araujo, Sheng Chen, John H. Zhang

“…Clinical trials performed using various stem cell types show promising results to their safety and effectiveness on reducing the effects of ischemic stroke in humans. Another important aspect of stem cell therapy discussed in this review is tracking endogenous and exogenous NSCs with magnetic resonance imaging. …”
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Eco-driving optimal control for electric vehicles with driver preferences by Roberto Lot, James Fleming, Boli Chen, Simos Evangelou

“…An optimal control formulation of an eco-driving system for front-wheel drive electric vehicles is proposed in this paper, demonstrating that including an optimal control model of driver preferences in such systems can successfully blend the objective of energy-efficiency with the subjective goals of human drivers, including desired following distances and time headways, a desired vehicle speed, smooth vehicle acceleration, and a comfortable corner negotiation speed. …”
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Factors Associated with Methicillin Resistant Staphylococcus aureus Carriage by Masood Abdulkareem Abdulrahman, Arazoo Issa Taher

“…S. aureus is a common commensal of the skin and mucosal membranes of humans, with estimates of 20% (range from 12% to 30%) of healthy people are persistent  S.  …”
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Low Cost Skin Segmentation Scheme in Videos Using Two Alternative Methods for Dynamic Hand Gesture Detection Method by Eman Thabet, Fatimah Khalid, Puteri Suhaiza Sulaiman, Razali Yaakob

“…On the contrary, there are certain challenges in using human skin colour as a feature to segment dynamic hand gesture, due to various illumination conditions, complicated environment, and computation time or real-time method. …”
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Deep learning in defects detection of PV modules: A review by Katleho Masita, Ali Hasan, Thokozani Shongwe, Hasan Abu Hilal

“…Traditional manual inspection methods are time-consuming, labor-intensive, and subject to human error, necessitating the development of automated, efficient detection techniques. …”
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Respiratory pathology in the mdx/utrn -/- mouse: A murine model for Duchenne Muscular Dystrophy (DMD). by Marán Y Hernández Rodríguez, Debolina D Biswas, Aoife D Slyne, Jane Lee, Evelyn Scarrow, Sarra M Abdelbarr, Heather Daniels, Ken D O'Halloran, Leonardo F Ferreira, Charles A Gersbach, Mai K ElMallah

“…The most studied DMD mouse model- the mdx mouse- has a milder respiratory phenotype compared to humans, likely due to compensatory overexpression of utrophin. mdx/utrn-/- mice lack both dystrophin and utrophin proteins. …”
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Serpina3k lactylation protects from cardiac ischemia reperfusion injury by Le Wang, Dandan Li, Fang Yao, Shanshan Feng, Chao Tong, Rongjia Rao, Meiyan Zhong, Xianqiang Wang, Wei Feng, Zhan Hu, Bo Jin, Li Wang, Shengshou Hu, Bingying Zhou

“…Both Serpina3k and its human homolog, SERPINA3, are abundantly expressed in cardiac fibroblasts, but not  in cardiomyocytes. …”
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Tissue Engineering of Urinary Bladder and Urethra: Advances from Bench to Patients by Hazem Orabi, Sara Bouhout, Amélie Morissette, Alexandre Rousseau, Stéphane Chabaud, Stéphane Bolduc

“…Autologous equivalents have already been produced for pigs (bladder) and human (urethra and bladder). The purpose of this paper is to present a review for the existing methods of engineering bladder and urethra and to point toward perspectives for their replacement.…”
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A review on speech recognition approaches and challenges for Portuguese: exploring the feasibility of fine-tuning large-scale end-to-end models by Yan Li, Yapeng Wang, Lap Man Hoi, Dingcheng Yang, Sio-Kei Im

“…Abstract At present, automatic speech recognition has become an important bridge for human-computer interaction and is widely applied in multiple fields. …”
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Interaction model estimation-based robotic force-position coordinated optimization for rigid–soft heterogeneous contact tasks by Haochen Zheng, Xueqian Zhai, Hongmin Wu, Jia Pan, Zhihao Xu, Xuefeng Zhou

“…Experimental validations were designed for two contact modes: “single-point contact” and “continuous contact”, involving materials with four different Young’s moduli and tested in human arm “relaxation–contraction” task. Results indicate that our framework ensures consistent geometry-aware parameter estimation and maintains reliable force interaction to guarantee safety. …”
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Sustainable Environmental Monitoring: Multistage Fusion Algorithm for Remotely Sensed Underwater Super-Resolution Image Enhancement and Classification by Wad Ghaban, Jawad Ahmad, Ali Akbar Siddique, Mohammad S. Alshehri, Anila Saghir, Faisal Saeed, Baraq Ghaleb, Mujeeb Ur Rehman

“…If compared with the land mass there are a lot of unexplored locations, a wealth of natural resources, and diverse ocean creatures that are inaccessible to us humans. Underwater rovers and vehicles play a vital role in discovering these resources, yet limited visibility in deep waters and technological constraints impede underwater exploration. …”
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