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17081
Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa
Published 2025-01-01“…Although underscored by animal studies, the endotypes of human RDEB are poorly understood. To fill this gap, we apply systems immunology approaches using single-cell high-dimensional techniques to capture the signature of peripheral immune cells and the diversity of metabolic profiles in RDEB adults, sampled outside of any opportunistic infection and active cancer. …”
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17082
Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons
Published 2016-01-01“…Transport of BDNF was altered at a very early time point after onset of human APP expression or after acute amyloid-beta(1-42) treatment, while the activity-dependent release of BDNF remained unaffected. …”
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17083
Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity
Published 2019-01-01“…Methods. Human ARPE-19 cells engineered to secrete high levels of the glial cell line-derived neurotrophic factor (GDNF) were encapsulated into hollow fiber membranes. …”
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17084
Effect of quercetin on the transport of ritonavir to the central nervous system in vitro and in vivo
Published 2016-03-01“…The aim of this study was to identify an effective flavonoid that could improve the intracellular accumulation of ritonavir in human brain-microvascular endothelial cells (HBMECs). …”
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17085
The lingering menace: How legacy organochlorine pesticides still threaten our rivers and food chains
Published 2025-01-01“…The bioaccumulation of organochlorine pesticides (OCPs) in aquatic organisms has been extensively explored in recent years due to associated ecological risks and potential threats to human health through food. This study aims to assess the bioaccumulation of organochlorine pesticides (OCPs) in 18 freshwater fish species from the Pearl River Delta, China. …”
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17086
Oxygenation of the Intraportally Transplanted Pancreatic Islet
Published 2016-01-01“…At our institutions, large human alloislets (>200 μm diameter) account for ~20% of total islet number but ~70% of total islet volume; since most of the total transplanted islet volume is accounted for by large islets, most of the intraportal islet cells are likely to be anoxic and not fully functional.…”
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17087
Prednisone inhibits osteosarcoma cell by regulating the Wnt/β-catenin signaling pathway
Published 2024-12-01“… Prednisone, a synthetic glucocorticoid, possesses a moderate duration of action in the human body. To investigate the effect of prednisone on osteosarcoma cells in vitro, CCK8, wound healing, Transwell assays, flow-cytometry, western blot, and ELISA were used to measure cell proliferation, cell migration, cell invasion, cell cycle, cell apoptosis, and the key proteins in Wnt/β-catenin pathway. …”
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17088
Investigating Stability Problems in Solid Waste Landfills
Published 2025-01-01“…The quality of groundwater has been seriously compromised due to improper storage methods. Problems related to human health and environmental pollution are more common in open dumps. …”
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17089
Influence of the cleaning method employed prior to the use of ionomeric materials in micro filtration of cavities at the cervical level
Published 2019-07-01“…Materials and Methods: In 40 human premolar teeth, cavities were prepared at the level of the cemetery amelo, the teeth were randomly divided into 4 groups (n: 10) received cleaning and restoration procedures according to the group, G1 cleaning with abrasive air and restoration with IV Ketac Molar Easy Mix (IVKM), G2 abrasive air and restoration with IV Gold Label 2 (IVGL), G3 pumice stone and IVKM, G4 pumice stone and IVGL. …”
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17090
Honduran nurses’ perceptions among the quality of care for stroke patients: a qualitative study
Published 2025-01-01“…Likewise, “positive outcomes regarding the nursing process”, defined as pleasant and helpful among the care of stroke patients, such as ethical and humanized caring, and activities on promoting patient self-care with involvement of the relatives. …”
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17091
A. A. ZINOVIEV ON THE TRANSFORMATION OF THE SOVIET MANAGERIAL ELITE
Published 2021-05-01“…Zinoviev considers it as a consequence of the death of the spirit of communism, that is, the state of human souls that were characteristic of the first stages of the life of the Soviet administrative elite, and raised the spiritual life of people to the unattainable heights of historical romance.…”
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17092
COVID-19 Seguridad de alimentos: Es el coronavirus un problema de seguridad en los alimentos?
Published 2020-04-01“…Written by Natalie Seymour, Mary Yavelak, Candice Christian, and Ben Chapman (NC State University Extension), and published by the UF/IFAS Food Science and Human Nutrition Department, April 2020. FSHN20-18s/FS363: COVID-19 Seguridad de alimentos: Es el coronavirus un problema de seguridad en los alimentos? …”
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17093
ELEMENTAL MUSIC-MAKING AS A HEALTH SAVING PHENOMENON IN THE SYSTEM OF GENERAL EDUCATION
Published 2015-03-01“…The traditional musical education focused mainly on musicology leads to artificial intellectualization, and leaves no room for chil-dren's imagination, intuition, creativity, joyful feelings and activities.The author discusses the specificity of the music teaching concept, developed by Carl Orff and his followers, and based on the complex understanding of human nature, history, living conditions, and corresponding with genetic laws. …”
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17094
RF Performance of Layer-Structured Broadband Passive Millimeter-Wave Imaging System
Published 2016-01-01“…Finally, passive millimeter-wave imaging of a car, a human, and a metal plate in clothes is demonstrated in this paper.…”
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17095
Predicting Solar Energetic Particle Events with Time Series Shapelets
Published 2025-01-01“…Solar energetic particle (SEP) events pose significant risks to both space and ground-level infrastructure, as well as to human health in space. Understanding and predicting these events are critical for mitigating their potential impacts. …”
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17096
Removal of Mercury from Coal-Fired Flue Gas and Its Sulfur Tolerance Characteristics by Mn, Ce Modified γ-Al2O3 Catalyst
Published 2020-01-01“…Mercury in coal-fired flue gas is the first human mercury emission source and has become the focus of national mercury pollution control. …”
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17097
A Review of Hybrid Process Development Based on Electrochemical and Advanced Oxidation Processes for the Treatment of Industrial Wastewater
Published 2022-01-01“…Nowadays, increased human activity, industrialization, and urbanization result in the production of enormous quantities of wastewater. …”
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17098
Integrating landscape ecological risk with ecosystem services in the Republic of Tatarstan, Russia
Published 2024-04-01“…Additionally, the results show that both maps have significant spatial disparities and that LER and ESs are negatively impacted by high human-socioeconomic activity. The integration of LER and ESs through the overlap of both maps provides a significant amount of spatial information for mapping, monitoring, management, and the protection of the fragile environment for sustainable landscape development and management.…”
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17099
Fuzzy Coordinated PI Controller: Application to the Real-Time Pressure Control Process
Published 2008-01-01“…This online conventional controller tuning technique will reduce the human involvement in controller tuning and increase the operating range of the conventional controller. …”
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17100
Climate change and agricultural productivity: Economic implications for food security
Published 2024-12-01“…These issues were compounded by the need to adapt agricultural methods and technologies to new climatic realities, which often require significant financial and human resources, particularly in developing countries with limited resources. …”
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