Glutamine and cancer: metabolism, immune microenvironment, and therapeutic targets by Ding Nan, Weiping Yao, Luanluan Huang, Ruiqi Liu, Xiaoyan Chen, Wenjie Xia, Hailong Sheng, Haibo Zhang, Xiaodong Liang, Yanwei Lu

“…Abstract Glutamine is the most abundant amino acid in human serum, and it can provide carbon and nitrogen for biosynthesis, which is crucial for proliferating cells. …”
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Intensified monsoonal rainstorm events over westerly-dominated Asian interior during the warm mid-Holocene by Peixian Shu, Weijian Zhou, Aaron E. Putnam, Baosheng Li, Shugang Kang, Yingying Sha, Zhengguo Shi, Guodong Ming, Hong Wang, Youbin Sun, David K. Wright, Weiguo Liu, Xiaodong Liu, Peng Cheng, Yougui Song, Dongfeng Niu, John R. Dodson, Hua Du, Jiaju Zhao, Zeke Zhang, Yahui Qiu, Zhisheng An

“…Abstract Hydroclimatic change in the Asian interior plays a key role in regulating regional environmental sustainability, water security, and human-nature relationships. However, the influence of the summer monsoon and westerly circulation on the evolution of hydroclimate over the arid Asian interior remains controversial. …”
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Accident Data-Driven Consequence Analysis in Maritime Industries by Jiahui Shi, Zhengjiang Liu

“…Their consequences are another important issue because they often involve significant economic losses and human casualties. Accident consequences do not occur randomly, but are triggered by a series of influential factors. …”
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Salmon Muscle Adherence to Polymer Coatings and Determination of Antibiotic Residues by Reversed-Phase High-Performance Liquid Chromatography Coupled to Selected Reaction Monitorin... by E. Zumelzu, M. J. Wehrhahn, O. Muñoz, F. Rull

“…The introduction of antibiotics is a matter of concern regarding the effects on human health and biodiversity. It is important to determine their impact on the adhesion of postmortem salmon muscle to can walls and the surface and structural changes affecting the functionality of multilayers. …”
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Corporate Carbon Footprint Analysis: Example Calculation for a Chemical Factory by Gözde Çolak, Burçin Atılgan Türkmen

“…In recent years, the concept of sustainable development has emerged as a concept associated with the risk that humanity will be unable to leave a livable world to future generations. …”
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Safety of Pegfilgrastim (Neulasta) in Patients with Sickle Cell Trait/Anemia by Pashtoon Murtaza Kasi, Mrinal M. Patnaik, Prema P. Peethambaram

“…Pegfilgrastim (Neulasta) is a recombinant filgrastim (human granulocyte colony-stimulating factor (G-CSF)) attached to a polyethylene glycol (PEG) molecule and is given as part of chemotherapy regimens that are associated with significant myelosuppression and risk for febrile neutropenia. …”
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Activator Protein-1 Transcriptional Activity Drives Soluble Micrograft-Mediated Cell Migration and Promotes the Matrix Remodeling Machinery by Martina Balli, Jonathan Sai-Hong Chui, Paraskevi Athanasouli, Willy Antoni Abreu de Oliveira, Youssef El Laithy, Maurilio Sampaolesi, Frederic Lluis

“…In this study, we identified the active protein-1 (AP-1) member Fos-related antigen-1 (Fra-1) to play a central role in the extracellular signal-regulated kinase- (ERK-) mediated enhanced cell migratory capacity of soluble micrograft-treated mouse adult fibroblasts and in the human keratinocyte cell model. Accordingly, we show that increased micrograft-dependent in vitro cell migration and matrix metalloprotease activity is abolished upon inhibition of AP-1. …”
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National and regional aspects of formation of physical culture and recreation environment in educational institutions of the Republic of Tatarstan by Manurov, Ilgiz M., Kalmanovich, Vladimir L.

“…The sports and recreation environment is a broad sphere imbued with the values of humanity and an abundance of educational opportunities. …”
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Self‐Driving Lab for Solid‐Phase Extraction Process Optimization and Application to Nucleic Acid Purification by Sebastian Putz, Jonathan Döttling, Tim Ballweg, Andre Tschöpe, Vitaly Biniyaminov, Matthias Franzreb

“…Through the integration of robotics, machine learning, and data‐driven experimentation, the SDL demonstrates a highly accelerated process optimization with minimal human intervention. In the multistep purification approach, the system is able to optimize buffer compositions for DNA extraction from complex samples, demonstrating effectiveness in both conventional chaotropic salt‐based methods and innovative chaotropic salt‐free buffers. …”
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Adult Hippocampal Neurogenesis in Parkinson’s Disease: Impact on Neuronal Survival and Plasticity by Martin Regensburger, Iryna Prots, Beate Winner

“…The pathology of the adult neurogenic niches in human PD patients is still mostly elusive, but different preclinical models have shown profound alterations of adult neurogenesis. …”
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A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η1-C2H4OMe)(DMSO)(phen)]+ (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells... by Federica De Castro, Erika Stefàno, Erik De Luca, Antonella Muscella, Santo Marsigliante, Michele Benedetti, Francesco Paolo Fanizzi

“…Recently, a novel Pt(II) complex, [Pt(ƞ1-C2H4OMe)(DMSO)(phen)]+ (phen =  1,10-phenanthroline), Pt-EtOMeSOphen, was synthesized and studied for its antitumor activity against eight human cancer cell lines. Pt-EtOMeSOphen showed higher cytotoxic effects than cisplatin in most of the cancer cell lines and in particular against the neuroblastoma cell line (SH-SY5Y). …”
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A Bichannel Transformer with Context Encoding for Document-Driven Conversation Generation in Social Media by Yuanyuan Cai, Min Zuo, Qingchuan Zhang, Haitao Xiong, Ke Li

“…We evaluate the proposed BCTCE by both automatic evaluation and human judgment. The experimental results on the dataset CMU_DoG indicate that the proposed model yields significant improvements over the state-of-the-art baselines on most of the evaluation metrics, and the generated responses of BCTCE are more informative and more relevant to dialogues than baselines.…”
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The Role of Digital Feedback on the Self-Esteem of Digital Natives by Şakir Güler, Murat Sezgin

“…The development of web technologies makes virtual platforms as an inseparable part of human life. This situation makes digital feedback highly effective on the self-esteem of individuals. …”
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Classification of Genes Based on Age-Related Differential Expression in Breast Cancer by Gunhee Lee, Minho Lee

“…As clinical transcriptome data have accumulated significantly, we classified all human genes based on age-specific differential expression between normal and breast cancer cells using public data. …”
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Form over Substance: Possibilities to Prove Electoral Irregularities under Serbian Law by Jelena Jerinić

“…Besides Serbian legislation and case law, the analysis leans on the relevant European standards, including the case law of the European Court of Human Rights. The results show that in practice, electoral commissions and courts use a limited circle of means of evidence and that the evidence submitted by complainants is not evaluated in the same way as the one coming from electoral boards. …”
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Genome Stability Pathways in Head and Neck Cancers by Glenn Jenkins, Kenneth J. O'Byrne, Benedict Panizza, Derek J. Richard

“…Variable functionality of an increasing spectrum of repair gene polymorphisms is associated with increased cancer risk, while aetiological factors such as human papillomavirus, tobacco and alcohol induce significantly different behaviour in induced malignancy, underpinned by differences in genomic stability. …”
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The Development of Cultural Ecotourism-Based Tourism: The Role of Village Governments in Managing Sustainable Tourism in Badung Regency by Juwita Pratiwi Lukman, I Putu Dharmanu Yudartha, Kadek Chyntia ktaviani, Ni Putu Diah Sintya Dewi, Selvia Widiyanti, Talitha Purnama Adristari

“…Recommendations include strengthening infrastructure, enhancing local community capacity, and implementing collaborative strategies to support the development of social sciences and humanities in the context of sustainable tourism.…”
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Ukraine-Russian Federation Relations within the Concepts of Security Dilemma and Responsibility To Protect (R2P) by Tuba Taşlıcalı Koç

“…Since the early ages of history, the need to feel safe in human beings has emerged and the instinct to act collectively for the purpose of self-protection has settled. …”
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Exploring Logical Intuition in Base-Rate Problems Using the Instructional Manipulation Paradigm by Debiao Zhu, Ping Lu, Zhujing Hu, Jianyong Yang, Dandan Nie

“…The study provides additional evidence for human rationality.…”
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Biofilm Compositions and Bacterial Diversity on Kitchen Towels in Daily Use by Yao Zhang, Kexin Li, Yibo Ru, Yue Ma

“…<i>Kocuria</i>, <i>Rothia</i>, <i>Psychrobacter</i>, <i>Enhydrobacter</i>, and <i>Pseudomonas</i> are genera of relatively high abundance that may originate from the human body and foods. In addition, correlations among environmental factors, major bacterial genera, physical properties, and biofilm formation of the towels were analyzed, which could provide a scientific reference for maintaining towel hygiene.…”
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