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15581
Failure evidences of reduced span bridges in case of extreme rainfalls - The case of Livorno
Published 2018-10-01“…Critical situations involving losses of human life and deterioration or failure of relevant structures are frequent. …”
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15582
Trastuzumab Resistance: Role for Notch Signaling
Published 2009-01-01“…Overexpression of ErbB-2 predicts for aggressive tumor behavior, resistance to some cytotoxic and antihormonal therapies, and poor overall survival. Trastuzumab, the humanized, monoclonal antibody directed against ErbB-2 has shown tremendous efficacy and improved overall survival for women when combined with a taxane-based chemotherapy. …”
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15583
Challenges of Studying Languages and Cultures in the Multicultural World
Published 2024-12-01“…Multilingualism and multiculturalism have been integral aspects of human civilization throughout history, yet they continue to present significant communicative challenges. …”
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15584
Echinococcus granulosus Prevalence in Dogs in Southwest Nigeria
Published 2014-01-01“…The result of this study established the presence of canine echinococcosis in Southwest Nigeria; thus there is the possibility of occurrence of zoonotic form of the disease (human cystic hydatid diseases) in the region.…”
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15585
Efficacy of Frontal Sinus as a Reliable Tool for Sex Differentiation – A Cross-Sectional Study
Published 2023-10-01“…Objective: Gender determination is pivotal in establishing a biological profile of human remains, where fragments of the skull persist with unidentifiable dental arch data. …”
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15586
Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma
Published 2025-01-01“…We identify a role for LECs as a source of extracellular 25-HC in tumors inhibiting PPAR-γ in intra-tumoral macrophages and monocytes, preventing their immunosuppressive function and instead promoting their conversion into proinflammatory myeloid cells that support effector T cell functions. In human melanoma, LECs also upregulate Ch25h, and its expression correlates with the lymphatic vessel signature, infiltration of pro-inflammatory macrophages, better patient survival, and better response to immunotherapy. …”
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15587
Investigating the relationship between the sense of belonging to the place and the level of social security of citizens - Case study: Qom-
Published 2021-06-01“…Human behaviors and activities of individuals are created in urban spaces, and cultural and social relationships are formed in these spaces. …”
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15588
Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8+ T cells
Published 2025-02-01“…Summary: The human brain harbors virus-specific, tissue-resident memory (TRM) CD8+ T cells. …”
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15589
Prostaglandin Receptor Signaling in Disease
Published 2007-01-01“…There are eight types of the prostanoid receptors conserved in mammals from mouse to human. They are the PGD receptor (DP), four subtypes of the PGE receptor (EP1, EP2, EP3, and EP4), the PGF receptor (FP), PGI receptor (IP), and TXA receptor (TP). …”
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15590
Pas de Deux: Active Ulcerative Colitis in an HIV-Positive Patient
Published 1996-01-01“…A 40-year-old male who was found to be human immunodeficiency virus-positive when he presented with bloody diarrhea in 1986 is described. …”
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15591
SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease
Published 2010-01-01“…The study of rare human genetic disorders has often led to some of the most significant advances in biomedical research. …”
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15592
Popular Psychology versus Scientific Evidence: Love Languages’ Factor Structure and Connection to Marital Satisfaction
Published 2021-01-01“…Love is an essential part of human experience and love languages have been studied to validate its factors’ structures to explain what makes people feel loved. …”
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15593
Quality of Life: A Case Report of Bullying in the Workplace
Published 2004-01-01“…Furthermore, it is often assumed that the executive/vice-chancellor, human resources, the trustees, or the governing board are unaware of bullying in their workplace. …”
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15594
Development of a methodological approach to the procedure for assessing the quality and effectiveness of the management decision–making mechanism
Published 2022-12-01“…Currently, active developments are underway to implement human and production resource management standards, new management mechanisms are emerging and being supplemented, but first of all, management activities can be assessed by the management decisions taken by the decision-maker, and the results that this management decision has brought. …”
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15595
Improvement of CRF-Based Saliency Detection Algorithm Using Matrix Decomposition Based Features
Published 2020-09-01“…One of the most important processing steps in the human vision system is the detection of a scene saliency map. …”
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15596
Neurogranin in Alzheimer's Disease: Roles in synaptic function, pathology, and potential as a diagnostic biomarker
Published 2024-09-01“…Thus, proteins involved in synaptic function, such as Ng, are of great interest in studying the disease. Some prior human studies have found that Ng, a protein involved in the regulation of synaptic function, is present at greater levels in the cerebrospinal fluid of people with AD compared with those without the disease. …”
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15597
Genome sequence of Streptomyces antioxidans MUSC 164T isolated from mangrove forest
Published 2018-04-01“…After 31 rounds of in vitro screening using human neuronal cell line (i.e. SH-SY5Y), the extract of 32 MUSC 164T was found to possess significant neuroprotective effect against hydrogen 33 peroxide[13]. …”
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15598
Application of Chaos Theory in Trucks' Overloading Enforcement
Published 2013-01-01“…Trucks' overloading is considered as one of the most substantial concerns in road transport due to a possible road surface damage, as well as, are less reliable performance of trucks' braking system. Sufficient human resource and adequate time scheduling are to be planned for surveying trucks' overloading; hence, it seems required to prepare an all-around model to be able to predict the number of overloaded vehicles. …”
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15599
Land system changes of terrestrial tipping elements on Earth under global climate pledges: 2000–2100
Published 2025-01-01“…They are highly sensitive to climate variations and serve as early warning signs of global change. Human activities, including global climate pledges, significantly influence the climate and the state of tipping elements. …”
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15600
Numerical Modelling of Building Vibrations due to Railway Traffic: Analysis of the Mitigation Capacity of a Wave Barrier
Published 2017-01-01“…Transmission of train-induced vibrations to buildings located in the vicinity of the track is one of the main negative externalities of railway transport, since both human comfort and the adequate functioning of sensitive equipment may be compromised. …”
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