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14961
A Pediatric Case of Cowden Syndrome with Graves’ Disease
Published 2017-01-01“…Cowden syndrome (CS) is a rare dominantly inherited multisystem disorder, characterized by an extraordinary malignant potential. In 80% of cases, the human tumor suppressor gene phosphatase and tensin homolog (PTEN) is mutated. …”
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14962
Age-Dependent Differences in Systemic and Cell-Autonomous Immunity to L. monocytogenes
Published 2013-01-01“…The systemic immune response to Listeria monocytogenes has been studied extensively in murine models; however, the clinical applicability of these findings to the human newborn remains incompletely understood. Furthermore, the ability to control infection at the level of an individual cell, known as “cell-autonomous immunity,” appears most relevant following infection with L. monocytogenes; as the main target, the monocyte is centrally important to innate as well as adaptive systemic immunity to listeriosis. …”
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14963
“Neither knowing nor not knowing”: Existential Anxiety and Ecological Certainty in the Poetry of W.S. Merwin
Published 2024-12-01“…This paper argues that Merwin’s poetry is constantly aware of the dangers caused by mankind’s impact on the environment, which has the effect of separating humanity from the natural world. In this situation Merwin is certain of the rights of animals and oppressed peoples, yet his poetic voice is less certain of his position in the world. …”
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14964
Research Progress on Mesenchymal Stem Cells for the Treatment of Diabetes and Its Complications
Published 2023-01-01“…Diabetes mellitus (DM) is a chronic disease that threatens human health. Although many drugs are available to treat DM, various complications caused by DM are unavoidable. …”
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14965
The “Ants of Cyprus” website: a dynamic, online awareness raising and conservation tool
Published 2025-01-01“…Ants are an important arthropod group due to their involvement in ecological processes amongst others as ecosystem engineers or predators, but some invasive alien species are also implicated in detrimental environmental, economic and human health effects. Despite recent advancements, the ant biodiversity of Cyprus is still in need of further research with previous online species inventories synthesising a checklist of just 65 native and 10 alien species. …”
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14966
Evolution of the C-Type Lectin-Like Receptor Genes of the DECTIN-1 Cluster in the NK Gene Complex
Published 2012-01-01“…Pattern recognition receptors are crucial in initiating and shaping innate and adaptive immune responses and often belong to families of structurally and evolutionarily related proteins. The human C-type lectin-like receptors encoded in the DECTIN-1 cluster within the NK gene complex contain prominent receptors with pattern recognition function, such as DECTIN-1 and LOX-1. …”
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14967
Roles of Oncogenic Long Non-coding RNAs in Cancer Development
Published 2018-12-01“…It has been shown that abnormal expression of lncRNAs is observed in several human solid tumors. Several studies have shown that many lncRNAs can function as oncogenes in cancer development through the induction of cell cycle progression, cell proliferation and invasion, anti-apoptosis, and metastasis. …”
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14968
Modeling the Combined Effect of Hepatitis B Infection and Heavy Alcohol Consumption on the Progression Dynamics of Liver Cirrhosis
Published 2022-01-01“…Liver cirrhosis is the liver scarring in human body which causes the liver organ failure to function its regular activities effectively and normally. …”
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14969
Green Route for Efficient Synthesis of Novel Amino Acid Schiff Bases as Potent Antibacterial and Antifungal Agents and Evaluation of Cytotoxic Effects
Published 2014-01-01“…Compounds have also been evaluated for cytotoxic effects against human colon cancer cell line Colo205.…”
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14970
The effect of career development and placement on job satisfaction which impacts the company's employee performance
Published 2024-03-01“…The company is one of the important sectors in improving the country's economy, and every company certainly wants optimal income. Therefore, human resources are an important aspect to continue improving as one of the driving forces so that the company runs optimally through work placements tailored to their abilities. …”
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14971
Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence
Published 2020-03-01“…We provided evidences showing that genotoxic injury, such as low dose irradiation, may promote an IGFBP-4 release in bloodstream both in mice irradiated with 100 mGy X-ray and in human subjects that received Computer Tomography. …”
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14972
M2 Macrophages Mediate the Resistance of Gastric Adenocarcinoma Cells to 5-Fluorouracil through the Expression of Integrin β3, Focal Adhesion Kinase, and Cofilin
Published 2020-01-01“…THP-1 cells were polarized using recombinant human IL-4, then were cocultured with AGS cells treated with fluorouracil. …”
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14973
Performance features of virus removal filters with novel regenerated cellulose hollow fiber membranes
Published 2025-02-01“…Following the revision of International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) Q5A, the guidelines for the virus safety of biopharmaceuticals now state that an effective viral clearance process should achieve a viral reduction of 4 log10 or greater. …”
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14974
Psychometric properties of the New Ecological Paradigm Scale (NEP)
Published 2024-01-01“…Climate change is a growing threat to humanity. Coping with its potentially disastrous effects will require a widespread behavioural change at both the societal and individual levels. …”
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14975
Machine learning algorithms can predict emotional valence across ungulate vocalizations
Published 2025-02-01“…This approach is critical in the field of emotional communication, where more information is needed to reach a better understanding of the emotional origins of human language. In addition, these results can help toward the development of automated tools for animal well-being monitoring.…”
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14976
Zamucoan ethnonymy in the 18th century and the etymology of Ayoreo
Published 2021-12-01“…Finally, although Ayoreo, “people, human beings,” is an autochthonous word, its adoption as an ethnonym is relatively recent and is due to social dynamics common to other Chacoan populations after the Chaco War.…”
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14977
The effect of educational games on the emotional intelligence of the children of 13-14 ages group
Published 2016-05-01“…Also, researchers should be encouraged to study these games which play an important role in human development and related studies should be supported.…”
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14978
Demographic Profile of Older Adults Using Wheeled Mobility Devices
Published 2011-01-01“…A total of 723 adults ageing 60 and older are representing three cohorts, from nursing homes, the Center for Assistive Technology, and the wheelchair registry from the Human Engineering Research Laboratories. Wheeled mobility devices were classified into three main groups: manual wheelchairs, power wheelchairs, and scooters. …”
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14979
A New Pixels Flipping Method for Huge Watermarking Capacity of the Invoice Font Image
Published 2014-01-01“…The proposed denoising method makes invoice font image smoother and fiter for human vision. Experiments show that the proposed flipping method not only keeps the invoice font structure well but also improves watermarking capacity.…”
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14980
Laser Therapy and Dementia: A Database Analysis and Future Aspects on LED-Based Systems
Published 2014-01-01“…First results concerning the measurement of the transmission factor (TF) through the human skull of a new LED- (light emitting diode-) based system are presented (TF = 0.0434 ± 0.0104 (SD)). …”
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