New Insights into the Androgen-Targeted Therapies and Epigenetic Therapies in Prostate Cancer by Abhijit M. Godbole, Vincent C. O. Njar

“…Herein, we provide an overview of the structure of human AR and its key structural domains that can be used as targets to develop novel antiandrogens. …”
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Effects of Type 2 Diabetic Serum on Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells by Xiangqun Deng, Min Xu, Moyu Shen, Jinluo Cheng

“…To clarify these conflicting findings, we investigated the effects of diabetic serum on the proliferation and osteogenic differentiation of mesenchymal stem cells (MSCs). We used human sera from subjects with different levels of glycemic control to culture the MSCs and induce osteogenic differentiation. …”
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IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells by Katie B. Shannon

“…IQGAPs are found in eukaryotic cells from yeast to human, and localize to actin-containing structures such as lamellipodia, membrane ruffles, cell-cell adhesions, phagocytic cups, and the actomyosin ring formed during cytokinesis. …”
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Investigation of the digital technologies influence on the process transformation in cinema by Yu. V. Vorontsova, D. N. Koltsov

“…Cinema is a particularly effective means of satisfying the human need for affective self-expression and establishing emotional communication between people. …”
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Anàlisi del Pacte de la Unió Europea sobre Migració i Asil by Magda Ennaji Térmens

“… Aquest article s’enfoca a analitzar el nou Pacte sobre Migració i Asil de la Unió Europea, centrant-me en dos punts principals: el procés negociador i els factors que han donat lloc a l’adopció del nou marc jurídic, i l’estudi de les disposicions normatives més controvertides i que susciten preocupació entre ONG, experts i activistes, pel seu enfocament securititzador de les fronteres exteriors de la Unió Europea, en comptes de basar-se en la protecció dels drets humans i que poden ocasionar, a la pràctica, possibles violacions del dret internacional i del Dret de la UE, especialment del dret d’asil. …”
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Application of emerging technologies for gut microbiome research by Wit Thun Kwa, Saishreyas Sundarajoo, Kai Yee Toh, Jonathan Lee

“…The gut microbiome is also a dynamic reflection of health status, which can be modified, thus representing great potential to exploit the mechanisms that influence human physiology. Recent years have seen a dramatic rise in gut microbiome studies, which has been enabled by the rapidly evolving high-throughput sequencing methods (i.e. 16S rRNA sequencing and shotgun sequencing). …”
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Preventing Foodborne Illness: Typhoid Fever—Salmonella Typhi by Keith R. Schneider, Renée Goodrich Schneider, Rachael Silverberg

“…Schneider, Renée Goodrich Schneider, and Rachael Silverberg, and published by the Food Science and Human Nutrition Department, January 2016. FSHN0514/FS125: Preventing Foodborne Illness: Typhoid Fever—Salmonella Typhi (ufl.edu) …”
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West Nile and Usutu viruses: current spreading and future threats in a warming northern Europe by Justine Laverdeur, Justine Laverdeur, Hélène Amory, Pablo Beckers, Daniel Desmecht, Frédéric Francis, Mutien-Marie Garigliany, Marie-Pierre Hayette, Annick Linden, Gilles Darcis

“…Climate change heavily threatens planetary and human health. Arboviral infections are best studied using the One Health concept, due to their reliance on complex interactions between environmental factors, arthropod vectors and vertebrate hosts. …”
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La crise de l’urbain et la condition moderne dans les romans de Saul Bellow by Timea Lönhardt

“…This paper proposes to study the correspondence that Saul Bellow’s novels establish between the urban crisis and the human condition in the United States of the second half of the twentieth century, which will eventually entail a discussion of the writer’s conception of the modern world in its social, political and intellectual aspects. …”
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Overview of Mink Immunity and Resistance to Pseudomonas aeruginosa by Jiangsong Bai, Xiao Wang, Zihui Zhang, Pengjing Lian, Jian Qiao

“…Pseudomonas aeruginosa is one of the most host-susceptible pathogenic bacteria to cause acute and chronic infections in humans and animals. Notably, its infection can especially cause fatal pathogenic infectious pneumonia in minks. …”
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Toxicity of Common Indoor Household Insecticides Registered in Florida by Frederick M. Fishel

“…Insecticides are designed to control insect pests, but they can also be toxic (poisonous) to desirable plants and animals, including humans. Some pesticides are so highly toxic that very small quantities can kill a person, and almost any pesticide can make people ill if they are exposed to a sufficient amount. …”
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Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application by Romilly E. Hodges, Deanna M. Minich

“…Research into human biotransformation and elimination systems continues to evolve. …”
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Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine by Wen-Chin Lee, Lung-Chih Li, Jin-Bor Chen, Hsueh-Wei Chang

“…In this study, we examined whether mitochondria play a pivotal role in modulating the effects of antioxidants during IS treatment. In the context of human umbilical vein endothelial cells, we found that IS had a dose-dependent antiproliferative effect. …”
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Quantitative Evaluation of Bacteria Adherent and in Biofilm on Single-Wall Carbon Nanotube-Coated Surfaces by Fabrizio Pantanella, Francesca Berlutti, Daniele Passeri, Daniela Sordi, Alessandra Frioni, Tiziana Natalizi, Maria Letizia Terranova, Marco Rossi, Piera Valenti

“…Biofilm is a common bacterial lifestyle, and it plays a crucial role in human health, causing biofilm-mediated infections. …”
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Recent Advances in Dipeptidyl-Peptidase-4 Inhibition Therapy: Lessons from the Bench and Clinical Trials by Jixin Zhong, Quan Gong, Aditya Goud, Srividya Srinivasamaharaj, Sanjay Rajagopalan

“…Although the cardiovascular effect of DPP4 inhibition has been substantially studied, the exact role of DPP4 in cardiovascular disease especially in humans remains elusive. Previous small studies and meta-analyses have suggested a benefit in both surrogate outcomes and cardiovascular events for these agents. …”
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E. coli-Produced BMP-2 as a Chemopreventive Strategy for Colon Cancer: A Proof-of-Concept Study by Saravanan Yuvaraj, Sa’ad H. Al-Lahham, Rajesh Somasundaram, Patrick A. Figaroa, Maikel P. Peppelenbosch, Nicolaas A. Bos

“…Here we demonstrate that transforming E. coli with a cDNA encoding an ileal-derived mature human BMP-2 induces effective apoptosis in an in vitro model system for colorectal cancer, whereas the maternal organism was not effective in this respect. …”
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Conditional Inactivation of HIF-1 Using Intrabodies by Arjan J. Groot, Eelke H. Gort, Elsken van der Wall, Paul J. van Diest, Marc Vooijs

“…The transcription factor Hypoxia-Inducible Factor 1 (HIF-1) is a key regulator in this response and frequently activated in human cancer. HIF-1 activation is associated with tumor aggressiveness and poor clinical outcome and, therefore, may provide an attractive therapeutic target. …”
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COVID-19 and post-disease features in patients with obesity by Ekaterina S. Frolova, Pavel P. Veselovsky, Galina A. Chumakova, Nadezhda G. Veselovskaya, Anna V. Ott

“…The COVID-19 pandemic has affected the global population, causing significant economic effect, material damage, and irreparable human losses. Many countries were forced to promptly reorganize their healthcare system in order to save patients with COVID-19. …”
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Towards cross-platform interoperability for machine-assisted text annotation by Richard Eckart de Castilho, Nancy Ide, Jin-Dong Kim, Jan-Christoph Klie, Keith Suderman

“…The study is conducted in the context of a specific annotation methodology, namely machine-assisted interactive annotation (also known as human-in-the-loop annotation). This methodology requires the ability to freely combine resources from different document repositories, access a wide array of NLP tools that automatically annotate corpora for various linguistic phenomena, and use a sophisticated annotation editor that enables interactive manual annotation coupled with on-the-fly machine learning. …”
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Tuberculous Osteomyelitis of the Scapular Spine Revealing HIV-1 Infection by Khaoula Idsaid, Malika Idalene, Khadija Danaoui, Wiam Ait Driss, Rania Elfargani, Nabila Soraa, Noura Tassi

“…The subtle clinical manifestation and association with human immunodeficiency virus infection poses obstacles for early diagnosis and management. …”
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