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14461
Species- and strain-specific microbial modulation of interferon, innate immunity, and epithelial barrier in 2D air–liquid interface respiratory epithelial cultures
Published 2025-01-01“…To explore how the microbiome’s biodiversity affects microbe-epithelial interactions, we screened 58 phylogenetically diverse microbes for their transcriptomic effect on human primary bronchial air–liquid interface (ALI) cell cultures. …”
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14462
Prediction of drug-drug plasma protein binding interactions of resveratrol in combination with celecoxib and leflunomide by molecular docking combined with an ultrafiltration techn...
Published 2020-03-01“…The present study is aimed at computational prediction of the molecular interactions between resveratrol, celecoxib, leflunomide and human serum albumin (HSA) and then investigates the plasma protein binding of resveratrol combined with celecoxib or leflunomide by an ultrafiltration technique. …”
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14463
Distributed Intelligent Assistance Robotic System with Sensor Networks Based on Robot Technology Middleware
Published 2014-06-01“…Besides, the system provides user human tracking services based on multifeature mean shift under the double-layer locating mechanism. …”
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14464
Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity
Published 2025-02-01“…In this review, we explore the potential mechanisms that govern cancer cell fusion, the molecular mediators involved, the metastatic characteristics acquired by fusion-derived hybrids, and their clinical significance in human cancer. Additionally, we discuss emerging pharmacological strategies aimed at targeting fusogenic molecules as a means to prevent metastatic dissemination.…”
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14465
Extension of the basic Global Health Security (GHS) index: Health system security indicator
Published 2021-01-01“…This extension of the GHS index provides a more reliable model for predicting the ability of a country's health system to provide an adequate response in a pandemic crisis when human health is seriously endangered. Evaluation of the results of the extension of the GHS index by additional non-medical predictors was performed using multiple linear regression analysis (MLRA), both for the basic and for the extended model. …”
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14466
Status prawny hermafrodytów w Rzymie
Published 2025-02-01“…Romans applied this term to describe peculiar phenomena caused—as they believed—by divine activity, which were aimed at indicating the imminent rupture of pax deorum, i.e. an accord between humans and the gods. The social norms established within ancient states were based on strict division of roles and functions, resulting from gender diff erentiation. …”
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14467
Les primates non humains sont-ils médecins ? Une analyse critique des études sur l’automédication et de ses mécanismes premiers
Published 2017-09-01“…Since the last 35 years, many researchers have worked on self-medication in non-human primates, and have explained the manifestation of some behaviours by therapeutic or prophylactic self-medication. …”
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14468
Un pays à l’image d’une jambe humaine : anatomie de l’imaginaire géographique et paysager italien
Published 2018-12-01“…This highly contemporary image is actually rooted in a much older image, which was just as popular during the Renaissance and which represented Italy as a human leg. This image first appeared in a geography book by Leandro Alberti dating from 1551, entitled Descrittione di tutta Italia, which was very successful during the Renaissance. …”
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14469
La Crucifixion aux saintes femmes du Grand séminaire de Strasbourg. Expressivité et sens de la nature dans l’art allemand vers 1520
Published 2023-03-01“…There are many features that evoke the Danube style, formerly known as the Donauschule : an intensely expressive atmosphere, a breath that animates the natural world and connects it with human beings, and the Mantegnesque motif of the group of Holy Women, taken from a woodcut by Albrecht Altdorfer. …”
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14470
Michel Foucault, Bruno Latour e algumas linhas de fuga na produção de conhecimentos
Published 2011-01-01“…Firstly, we gather questionings about the epistemological bases on which psychology has been founded in order to become scientific, as well as about the dichotomy between natural sciences and human sciences. Secondly, we turn our attention to Foucault's and Latour's works to discuss rituals of production and regulation of scientific discourses. …”
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14471
A narrativa mediada e a permanência da tradição: percurso de um anti-herói brasileiro
Published 2011-01-01“…They still retain, however, the authentic dramatic models to represent human life.…”
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14472
Non-Drug and Non-Invasive Therapeutic Options in Alzheimer’s Disease
Published 2025-01-01“…Singly or as an applied technique to change the permeability of the blood–brain–barrier (BBB), FUS and TPS have demonstrated the benefits of use in treating AD in animal and human studies. Adipose-derived stem Cells (ADSCs), gene therapy, and many other alternative methods (diet, sleep pattern, physical exercise, nanoparticle delivery) are also new potential treatments since multimodal approaches represent the modern trend in this disorder research therapies.…”
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14473
Using omega 3 as an anti-aging treatment
Published 2020-12-01“…Skin aging can be divided into chronological aging and photoaging, the latter being activated through damage to human skin, attributable to repeated exposure to ultraviolet (UV) rays from sunlight. …”
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14474
Risk Management for 4-H Youth Development Work: Large Animals—Livestock
Published 2016-02-01“…This 8-page fact sheet covers risks in the following categories: injuries to people, injuries to animals, property damage, biosecurity (diseases transmitted to humans and between animals), and general precautions. …”
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14475
Image establishment of a higher education institution lecturer in the new educational environment
Published 2022-04-01“…The study uses institutional and structural analysis methods, system analysis methods, human capital research methods, panel research and data collection method. …”
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14476
Synthesis, Characterization, and Anticancer Activity of New Metal Complexes Derived from 2-Hydroxy-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide
Published 2015-01-01“…The cytotoxic activity of the ligand and its metal complexes showed potent cytotoxicity effect against growth of human liver cancer HepG2 cell lines compared to the clinically used Sorafenib (Nexavar).…”
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14477
APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage
Published 2024-12-01“…Aim: The aim of this study was to assess the utility of weighted amide proton transfer (APTw) MRI in three different rodent models of hepatocellular carcinoma (HCC).Methods: APTw MRI was evaluated in models of diethylnitrosamine (DEN) induced HCC, N1S1 syngeneic orthotopic xenograft and human HepG2 ectopic xenograft.Results: All models of HCC showed a higher APTw signal over the surrounding normal tissues. …”
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14478
Transcription factor specificity protein (SP) family in renal physiology and diseases
Published 2025-01-01“…A detailed analysis of their expression and cellular localization in the healthy human kidney is presented, highlighting their involvement in fatty acid metabolism, electrolyte regulation, and the synthesis of important molecules. …”
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14479
Unified Fingerprinting/Ranging Localization in Harsh Environments
Published 2015-11-01“…Context-awareness in wireless sensor networks (WSNs) relies mainly on the position of objects and humans. The provision of this positional information becomes challenging in the harsh environmental conditions where WSNs are commonly deployed. …”
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14480
Le sens géographique du jardin « individuel » et sa relation au paysage
Published 2020-12-01“…How can the "individual" garden become a part of the objects and tools used by the geographer to apprehend the human environment? How does this question relate to the seemingly wider question of the ways in which the notion of the landscape is used in geography? …”
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