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Betacoronaviruses Differentially Activate the Integrated Stress Response to Optimize Viral Replication in Lung-Derived Cell Lines
Published 2025-01-01“…The betacoronavirus genus contains five of the seven human coronaviruses, making it a particularly critical area of research to prepare for future viral emergence. …”
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14223
<i>Toxoplasma gondii</i> and Rabies—The Parasite, the Virus, or Both?
Published 2025-01-01“…<i>Toxoplasma gondii</i> is an intracellular protozoan parasite that infects a wide range of vertebrates, including humans. Although cats are the only definitive host, any warm-blooded animal can act as a paratenic host. …”
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14224
Algorithm of Behaviour of Virtual Avatars During Public Speaking Training in a VR Environment
Published 2024-12-01“…The virtual avatars, powered by the algorithm, were able to simulate realistic human behaviours and responses, thus providing a more engaging and immersive learning experience for users. …”
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Penggunaan Compressive Sensing pada Pengenalan Huruf dengan Tulisan Tangan Menggunakan Metode K-Nearest Neighbor
Published 2022-12-01“…Abstract Retrieval, delivery, or exchange of information in the form of data is needed by humans. Human life requires information quickly and precisely, so data are used so it doesn't take up a lot of bandwidth and memory capacity when it arrive at the server. …”
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Contralateral Posterior Chamber Phakic Intraocular Lens Implantation as Rehabilitation of Refractive Lens Exchange with a Monofocal Intraocular Lens in a Young, Nonpresbyopic, Bila...
Published 2019-01-01“…Refractive errors are widespread in the human population; nowadays, numerous surgical options allow for efficient and safe correction them. …”
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IMRAS-Immunization with radiation-attenuated Plasmodium falciparum sporozoites by mosquito bite: Cellular immunity to sporozoites, CSP, AMA1, TRAP and CelTOS.
Published 2021-01-01“…<h4>Background</h4>Immunization with radiation-attenuated sporozoites (RAS) by mosquito bites provides >90% sterile protection against Plasmodium falciparum malaria in humans. We conducted a clinical trial based on data from previous RAS clinical trials that suggested that 800-1200 infected bites should induce ~50% protective vaccine efficacy (VE) against controlled human malaria infection (CHMI) administered three weeks after the final immunization. …”
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Disease-Associated Dopamine Receptor D2 Variants Exhibit Functional Consequences Depending on Different Heterotrimeric G-Protein Subunit Combinations
Published 2024-12-01“…We were able to confirm the reported gain-of-function phenotype by Rodriguez-Contreras et al. and extend it by the use of the most abundant heterotrimeric G-protein subunits, Gα<sub>oA</sub> and Gα<sub>i1</sub>, β<sub>1</sub> and β<sub>2</sub>, and γ<sub>3</sub> and γ<sub>7</sub>, in mouse and human basal ganglia. <b>Conclusions:</b> Although our results indicate that the interaction of the two variants with the most highly expressed heterotrimeric G-protein complex subunit combinations also results in a gain-of-function phenotype, they also clearly demonstrate that the phenotype can be significantly altered, dependent on heterotrimeric G-protein complex expression.…”
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Skin-associated Corynebacterium amycolatum shares cobamides
Published 2025-01-01“…Our study provides a unique model to study metabolite sharing by microorganisms, which will be critical for understanding the fundamental interactions that occur within complex microbiomes and for developing approaches to target the human microbiota for health advances.IMPORTANCEThe human skin serves as a crucial barrier for the body and hosts a diverse community of microbes known as the skin microbiome. …”
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A patient choice‐driven lifestyle intervention lowers HbA1c in type 2 diabetes: A feasibility study
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Risk Factors Associated with Leishmaniasis in the Most Affected Provinces by Leishmania infantum in Morocco
Published 2020-01-01“…Background. Human leishmaniasis, both visceral and cutaneous, has been reported in Morocco for centuries and constitutes a serious public health problem. …”
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RELEVANSI PEMIKIRAN IRIGARAY TERHADAP ARSITEKTUR
Published 2018-12-01“…Abstract_ Architectural theory was born from several philosophical thoughts which discussed the relationship between humans and space. The thought of the philosophers explained how to understand humans as users of architectural products. …”
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Comparison of miRNA expressions among benign, premalignant and malignant lesions of the larynx: could they be transformation biomarkers?
Published 2021-02-01“…Finding a biomarker to overcome these concerns are ongoing challenges and recently microRNAs (miRNAs) are attributed as possible candidates since they can regulate gene expressions in the human genome. The objective of our study was to investigate their capability as a transformation biomarker for malignant laryngeal lesions. …”
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Practice and effectiveness evaluation of integrated teaching of life education and hospice & palliative care for undergraduates in a medical college in Shanghai
Published 2024-11-01“…ObjectiveLife education and hospice & palliative care (HPC) involve many aspects of medicine, humanities and education, which is not only an important public health issue, but also an important livelihood issue and education issue widely concerned at home and abroad. …”
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TO THE BASICS OF MODERN POLITICAL ANTHROPOLOGY: FREEDOM AND JUSTICE IN THE SOCIAL CONTRACT THEORY OF T. HOBBES
Published 2020-06-01“…Thanks to Hobbes, the idea of external humility in disobedience to the inner, of freedom of conscience as a "human and citizen", of an understanding of individual independence, which is not just a permissible but accepted by state power, has been acquired with exceptional theoretical and practical meaning. …”
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Distinct neural computations scale the violation of expected reward and emotion in social transgressions
Published 2025-01-01“…Abstract Traditional decision-making models conceptualize humans as adaptive learners utilizing the differences between expected and actual rewards (prediction errors, PEs) to maximize outcomes, but rarely consider the influence of violations of emotional expectations (emotional PEs) and how it differs from reward PEs. …”
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