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DeepDrug as an expert guided and AI driven drug repurposing methodology for selecting the lead combination of drugs for Alzheimer’s disease
Published 2025-01-01“…Abstract Alzheimer’s Disease (AD) significantly aggravates human dignity and quality of life. While newly approved amyloid immunotherapy has been reported, effective AD drugs remain to be identified. …”
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13586
Liver and Nutrition. An Optimal Diet for Non-Alcoholic Fatty Liver Disease
Published 2018-11-01“…The molecular mechanisms of beneficial effects on human health have been confirmed for such Mediterranean diet components as polyphenols, carotenoids, oleic acid, polyunsaturated fatty acids and dietary fiber. …”
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The Idea of Education: Development or Service Delivery?
Published 2020-05-01“…The logical-semantic analysis, hermeneutic method and synthesis of the views among the representatives in the filed of the humanities were used to study the phenomenon of “educational services”. …”
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Assessment of Groundwater Potential Zones of Upper Blue Nile River Basin Using Multi-Influencing Factors under GIS and RS Environment: A Case Study on Guder Watersheds, Abay Basin,...
Published 2022-01-01“…Groundwater is the most crucial resource for human beings and plays an important role in combating climate change and is substantial to human existence on the globe. …”
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High Doses of Halotolerant Gut-Indigenous Lactobacillus plantarum Reduce Cultivable Lactobacilli in Newborn Calves without Increasing Its Species Abundance
Published 2017-01-01“…In contrast to studies where human-derived Lactobacillus LGG or rhamnosus had notoriously high, but short-lived, colonization, we found that L. plantarum colonized stably with fecal shedding of 6±1 log10·g−1 (irrespective of dose, P>0.2). …”
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Cell-Specific Regulation of Inflammatory Cytokines and Acute-Phase Proteins by the Glucocorticoid Receptor
Published 2023-01-01“…This study was performed to understand the glucocorticoid receptor’s (GR’s) effects on chemokine and acute-phase protein expression in human liver, in settings of bacterial infection (modeled using LPS) or inflammation (modeled using TNFα). …”
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Genes related to the white face colour pattern in eight Russian cattle breeds
Published 2018-04-01“…It is possible that white colour of livestock animals had aesthetic significance for humans as well. The first step towards detection of genes and mutations controlling white colouring in animals is the genome-wide association studies. …”
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Smart Healthy Schools: An IoT-enabled concept for multi-room dynamic air quality control
Published 2024-01-01“…In the post-pandemic era, equipping schools with a network of smart IoT sensors has become critical to aspire for the optimal control of the IAQ and lowering the airborne infection risk of several pathogens, indirectly related to cumulated human emitted CO2 levels over time. Thermal energy waste in winter due to improved air renewal remains of major concern but can be well monitored within a SHS monitoring architecture thanks to the flexibility of the LoRaWAN protocol able to process also a large amount of energy and climatic data at room and building scale. …”
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Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins
Published 2002-01-01“…Its aspirin-triggered 15R epimer (15-epi-LXA4) and their bioactive stable analogs act in the subnanomolar to nanomolar range in human cellular systems and murine models of acute inflammation and reperfusion. …”
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Effect of Walking Modes and Temperatures on the Robustness of Ventilation Systems in the Control of Walking-induced Disturbances
Published 2022-06-01“…The database and method developed in this study could be beneficial for the control of human walking-induced disturbances in those settings that require a highly controlled indoor environment.…”
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lnc-MRGPRF-6:1 Promotes ox-LDL-Induced Macrophage Ferroptosis via Suppressing GPX4
Published 2023-01-01“…Likely, we constructed lnc-MRGPRF-6:1 knockdown and overexpression of human monocyte-derived macrophages and detected the expression levels of ferroptosis-related biomarkers. …”
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Meta-analysis examining the association between low platelet monoamine oxidase levels and Zuckerman's sensation seeking scale in a sex dependent manner
Published 2025-02-01“…MAO levels can be measured in humans by collecting blood platelets. Low platelet MAO levels in healthy individuals are associated with personality differences, such as increases in sensation seeking. …”
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Assessing the impact of climate and land use change on flood vulnerability: a machine learning approach in coastal region of Tamil Nadu, India
Published 2025-01-01“…Abstract Flooding and other natural disasters threaten human life and property worldwide. They can cause significant damage to infrastructure and disrupt economies. …”
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Legality as a principle of court activity in respecting the rights, freedoms and interests of minors in cases of administrative offences
Published 2024-12-01“…The study focuses on the empirical aspect of the application by courts of the Constitution and laws of Ukraine regarding the observance of human rights and freedoms in proceedings on administrative offences involving certain categories of citizens who need additional protection – minors. …”
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Holarctic phylogeographic structure of Eurasian wigeon (Mareca penelope)
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