Toxic Assessment of Heavily Traffic-related Fine Particulate Matter Using an in-vivo Wild-type Caenorhabditis elegans Model by Meng-Ching Chung, Kuo-Lin Huang, Japheth L. Avelino, Lemmuel L. Tayo, Chih-Chung Lin, Ming-Hsien Tsai, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Ching-Kai Su, Sen-Ting Huang

“…The nematodes exposed PM2.5 models not only posed potentially adverse health effects on human but also represented ecotoxic impacts on the ecosystem. …”
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Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease, by regulating LPCAT3 by Majd B. Protty, Victoria J. Tyrrell, Ali A. Hajeyah, Bethan Morgan, Daniela Costa, Yong Li, Anirban Choudhury, Rito Mitra, David Bosanquet, Alex Reed, Iuliia K. Denisenko, Katsuyuki Nagata, Hideo Shindou, Benjamin F. Cravatt, Alastair W. Poole, Takao Shimizu, Zaheer Yousef, Peter W. Collins, Valerie B. O’Donnell

“…Furthermore, the Lands cycle acyl-transferases that catalyze their formation are unidentified. eoxPL were measured in platelets and leukocytes from an atherosclerotic cardiovascular disease (ASCVD) cohort and retrieved human arterial thrombi from three anatomical sites. …”
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Artificial intelligence-driven ensemble deep learning models for smart monitoring of indoor activities in IoT environment for people with disabilities by Munya A. Arasi, Hussah Nasser AlEisa, Amani A. Alneil, Radwa Marzouk

“…Conventional machine learning and deep learning approaches effectively detect human activity. This study develops and designs a metaheuristic optimization-driven ensemble model for smart monitoring of indoor activities for disabled persons (MOEM-SMIADP) model. …”
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Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy by Christopher R. Starr, Assylbek Zhylkibayev, Oleg Gorbatyuk, Alli M. Nuotio-Antar, James Mobley, Maria B. Grant, Marina Gorbatyuk

“…Furthermore, ARPE-19 cells were infected with lentiviral particles expressing human ChREBP (ARPE-19^ChREBP) and subjected to global proteomics. …”
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Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs by Elias A. Said, Sumaya Al-Dughaishi, Wadha Al-Hatmi, Iman Al-Reesi, Mohammed S. Al-Balushi, Atika Al-Bimani, Juma Z. Al-Busaidi, Marwa Al-Riyami, Murtadha Al-Khabori, Salam Al-Kindi, Francesco A. Procopio, Shadia Al-Sinawi, Aliyaa Al-Ansari, Crystal Y. Koh, Khalid Al-Naamani, Ali A. Al-Jabri

“…We investigated whether NAS TLRs can induce MK and PTN production by human iAPCs, namely monocytes, macrophages, MDDCs, myeloid dendritic cells (mDCs), and pDCs. …”
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The Fibularis Quartus Muscle: A Cadaveric Case Report with Historical, Embryological, Molecular and Clinical Considerations by Dibakar Borthakur, Rajesh Kumar, Namaschivayam G R, Mohammed Ahmed Ansari, Seema Singh

“… Introduction: The fibularis quartus (FQ) or peroneus quartus (PQ) is a supernumerary muscle occasionally seen in the lateral compartment of the human leg. It is a weak evertor and has a role in pronation and lateral stabilization of the foot. …”
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In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic... by Anders Bruun Mathiasen, Abbas Ali Qayyum, Erik Jørgensen, Steffen Helqvist, Annette Ekblond, Michael Ng, Kishore Bhakoo, Jens Kastrup

“…While regenerative stem cell therapy for ischemic heart disease has moved into phase 3 studies, little is still known about retention and migration of cell posttransplantation. In human studies, the ability to track transplanted cells has been limited to labeling with radioisotopes and tracking using nuclear imaging. …”
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Response of the gut microbiome and metabolome to dietary fiber in healthy dogs by Amrisha Bhosle, Matthew I. Jackson, Aaron M. Walsh, Eric A. Franzosa, Dayakar V. Badri, Curtis Huttenhower

“…Thus, our study corroborates findings in human cohorts and reinforces the role of personalized microbiomes even in seemingly phenotypically homogeneous subjects.IMPORTANCEConsumption of dietary fiber changes the composition of the gut microbiome and, to a larger extent, the associated metabolites. …”
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Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity by Caitlin V. Lewis, Antony Vinh, Henry Diep, Chrishan S. Samuel, Grant R. Drummond, Barbara K. Kemp-Harper

“…Amplex Red and DCF fluorescence assays detected increased hydrogen peroxide generation following stimulation with IL-4, but not IFN-γ+LPS. Coculture with human aortic adventitial fibroblasts revealed that M(IL-4), but not M(IFN-γ+LPS), enhanced fibroblast collagen 1 protein expression. …”
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In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity by R. Deveswaran, D.J. Madhu Kumar, V. Madhavan, Soma Chaki, Misbah Khan, Govind R. Kadambi, B.V. Basavaraj, J. Anbu

“…Cell line studies using human gingival fibroblasts demonstrated that higher doses of the extracts exhibited a mitogenic effect, with a plateau observed at higher concentrations. …”
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Retinoblastoma-binding Protein 9 Suppresses Intestinal Inflammation and Inflammation-induced Tumorigenesis in MiceSummary by Kensuke Hamada, Yuki Nakanishi, Yu Muta, Mayuki Omatsu, Kosuke Iwane, Munehiro Ikeda, Jiayu Chen, Yoko Masui, Naoki Aoyama, Nobukazu Agatsuma, Go Yamakawa, Takahiro Utsumi, Hiroki Kitamoto, Makoto Okabe, Yoshiro Itatani, Takumi Adachi, Koubun Yasuda, Shuji Yamamoto, Akihisa Fukuda, Etsushi Kuroda, Masaki Ohmuraya, Kazutaka Obama, Seiichi Hirota, Hiroki Ikeuchi, Kenji Nakanishi, Hiroshi Seno

“…However, the functional role of RBBP9 in ulcerative colitis (UC) and colitis-associated cancer (CAC) remains elusive. Methods: Human samples of UC and CAC were examined by immunohistochemical and bioinformatics analyses. …”
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Recombinant short TNF-BD protein from smallpox virus is pharmacologically active in an experimental septic shock model by I. P. Gileva, S. N. Yakubitskiy, I. V. Kolosova, S. N. Shchelkunov

“…Tumor necrosis factor (TNF) is one among the key cytokines that mediate the immune system to protect humans against viral infections. Throughout evolution, anthropogenic Variola virus (VARV) has developed effective mechanisms to overcome human defense reactions. …”
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A ten-year evaluation of central nervous system cystic echinococcosis in a highly endemic area of Iran: Molecular epidemiology and clinicopathological characteristics by Mohsen Najjari, Ali Dehesht Manesh, Shahab Rezaeian, Bibi Razieh Hosseini Farrash, Mohammad Ali Mohammadi, Mohammad Ebrahimipour

“…Cystic echinococcosis can involve various organs in humans with the brain and spine being particularly vulnerable. …”
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Genotyping <em> Escherichia coli </em> O157:H7 strains isolated from cattle and small ruminants in Fars province (Iran) using Enterobacterial Repetitive Intergenic Consensus PCR A... by Sedigheh Mokhtari, Yahya Tahamtan, Mohammad Kargar, Keyvan Tadayon, Elham Moazamian

“… Background: Shiga toxin-producing Escherichia coli (STEC) strains are bacteria that cause gastrointestinal illnesses in humans. The strain E. coli O157:H7 diarrhea, hemorrhagic colitis, and hemolytic-uremic syndrome in humans. …”
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mtlA, a novel typing gene offering enhanced resolution for pandemic Vibrio species by Lei Zhou, Danlei Liu, Zilong Zhang, Yongqiang Zhu, Huajun Zheng

“…Around 13 species of Vibrio are known to cause infections in humans. Without appropriate medical interventions, the consequences of these infections can escalate to become life-threatening. …”
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Behaviour of post-tensioned benches made of high-content recycled aggregate concrete reinforced with racquet string fibres by Narakorn Suwannachote, Thanongsak Imjai, Fetih Kefyalew, Radhika Sridhar, Reyes Garcia, U. Johnson Alengaram, Sivakumar Naganathan

“…Tests were carried out to evaluate 1) static loading behaviour, 2) long-term behaviour after 365 days of sustained loading, and 3) human-induced vibrations. The static test results show that benches with 100% RAC and PTMS had higher capacity (by about 25%) that counterpart benches without PTMS. …”

Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traitsResearch in context by Lennart Riemann, Rodrigo Gutierrez, Ivan Odak, Joana Barros-Martins, Lennart M. Roesner, Ximena Leon Lara, Christine Falk, Thomas F. Schulz, Gesine Hansen, Thomas Werfel, Reinhold Förster, Berislav Bošnjak, Felix Jenniches, Norman Klopp, Till Robin Lesker, Martin Stangel

“…Summary: Background: Aging increases disease susceptibility and reduces vaccine responsiveness, highlighting the need to better understand the aging immune system and its clinical associations. Studying the human immune system, however, remains challenging due to its complexity and significant inter-individual variability. …”
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The role of light and vision in farmed ungulates and implications for their welfare by Julia Stuhlträger, Eberhard von Borell, Jan Langbein, Christian Nawroth, Maria Vilain Rørvang, Camille M. C. Raoult, Camille M. C. Raoult

“…In the past, animal environments have been designed primarily to optimize production output and adjusted to human needs. This emphasis has changed toward a more animal-based focus. …”
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The expression profile of genes associated with behavior, stress, and adult neurogenesis along the hippocampal dorsoventral axis in tame and aggressive foxes by Yu. V. Alexandrovich, E. V. Antonov, S. G. Shikhevich, A. V. Kharlamova, L. V. Meister, Y. V. Makovka, D. V. Shepeleva, R. G. Gulevich, Yu. E. Herbeck

“…It is presumed that these genes constitute an important part of the mechanism reducing stress induced by contacts with humans and contribute to linking stress regulation with adult neurogenesis in tame foxes and domesticated animals in general.…”
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Genetic and biochemical characterization of staphylococci occurring in Novosibirsk, Russia by Y. N. Kozlova, N. V. Fomenko, V. V. Morozova, I. V. Saranina, A. Yu. Tikunov, D. A. Ganichev, A. G. Samokhin, V. V. Pavlov, O. M. Rozhnova, I. A. Bondar’, E. V. Zenkova, V. V. Nimaev, V. V.  Klimontov, N. V. Tikunova

“…Staphylococci are capable of penetrating many human tissues and organs, causing superficial and deep purulent infections, respiratory and urinary tract infections, food poisoning and intoxication. …”
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