Mono-allelic epigenetic regulation of polycistronic transcription initiation by RNA polymerase II in Trypanosoma brucei by Rudo Kieft, Laura Cliffe, Haidong Yan, Robert J. Schmitz, Stephen L. Hajduk, Robert Sabatini

“…Trypanosoma brucei brucei is unable to infect humans because of its susceptibility to an innate immune complex, trypanosome lytic factor (TLF) in the circulation of humans. …”
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River water quality monitoring using machine learning with multiple possible in-situ scenarios by Dani Irwan, Saerahany Legori Ibrahim, Sarmad Dashti Latif, Chris Aaron Winston, Ali Najah Ahmed, Mohsen Sherif, Amr H. El-Shafie, Ahmed El-Shafie

“…Future studies should concentrate on resolving these issues and investigating other elements, such as environmental variables, land use patterns, and human activity, that may affect the forecast of water quality.…”
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Study of the Shock Absorption Effectiveness of Air Cushions by Jacek Roguski, Leszek Jurecki, Ryszard Łyszczek, Krzysztof Cygańczuk

“…The basic principles of operation of the jump cushion are based on controlled absorption of the kinetic energy of the human body falling from a great height. Thanks to the use of air layers and flexible energy-absorbing materials, the jump cushion is able to reduce the overload affecting the human body during contact with the shock-absorbing surface. …”
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Harmful impacts of microplastic pollution on poultry and biodegradation techniques using microorganisms for consumer health protection: A review by Mohamed E. Abd El-Hack, Elwy A. Ashour, Fatemah AlMalki, Asmaa F. Khafaga, Mahmoud Moustafa, Mohammed O. Alshaharni, Islam M. Youssef, Ahmed A. Elolimy, Sylwester Świątkiewicz

“…This review focuses on the effects of microorganisms in removing microplastic pollution, the detrimental impact of microplastics on poultry production, and the connection between microplastic pollution and human health.…”
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MRI-based analysis of the microstructure of the thalamus and hypothalamus and functional connectivity between cortical networks in episodic cluster headache by Chiara Abagnale, Antonio Di Renzo, Giada Giuliani, Gabriele Sebastianelli, Francesco Casillo, Lucia Ziccardi, Vincenzo Parisi, Cherubino Di Lorenzo, Mariano Serrao, Francesca Caramia, Vittorio Di Piero, Gianluca Coppola

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Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression by Kasper Recourt, Joop Van Gerven, Joop Van Gerven, Nadieh Drenth, Jeroen van der Grond, Kantaro Nishigori, Nic J. Van Der Wee, Gabriël E. Jacobs, Gabriël E. Jacobs

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Considérations ontogénétiques et phylogénétiques concernant l’origine de la parole by Louis-Jean Boë, Jean Granat, Jean-Louis Heim, Jean-Luc Schwartz, Pierre Badin, Guillaume Barbier, Guillaume Captier, Antoine Serrurier, Nicolas Kielwasser

“…We analyzed 31 skulls from now to 1.5 Ma (millions years) BP (Before Present) for fossil hominids available at the Muséedel’Homme in Paris or in the literature: (1) 10-30 ka BP: modern humans: Paleolithic; (2) 90-200 ka BP: anatomically modern humans; (3) 45-90 ka BP: Neanderthals; (4) 1.5 Ma BP: Homoergaster; These skulls are all well kept and possess a jaw in the majority of cases but the vertebral column has been reconstituted. …”
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Clinical Holistic Medicine: Metastatic Cancer by Søren Ventegodt, Elin Solheim, Mads E. Saunte, Mohammed Morad, Isack Kandel, Joav Merrick

“…This paper describes how work with a patient with metastasized cancer can be done in the holistic clinical practice in 14 days on an individual basis, helping the patient to recover her human character, purpose of life, coherence, and will to live, thus improving quality of life and possibly also survival time. …”
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Exploiting somatic oncogenic driver alterations in a patient with Li-Fraumeni syndrome– paving the path towards precision medicine: a case report by Carolin Seeling, Sonja Dahlum, Ralf Marienfeld, Vera Jan, Brigitte Rack, Uwe Gerstenmaier, Ambros J. Beer, Regine Mayer-Steinacker, Wolfgang Thaiss, Thomas F. E. Barth, Thomas Seufferlein, Nadine T. Gaisa, Stephan Stilgenbauer, Wolfgang Janni, Reiner Siebert, Hartmut Döhner, Verena I. Gaidzik

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Genetic context modulates aging and degeneration in the murine retina by Olivia J. Marola, Michael MacLean, Travis L. Cossette, Cory A. Diemler, Amanda A. Hewes, Alaina M. Reagan, Jonathan Nyandu Kanyinda, Daniel A. Skelly, Gareth R. Howell

“…Therefore, examining molecular aging in the retina across different genetic backgrounds will enhance our understanding of human-relevant aging and degeneration in both the retina and brain—potentially improving therapeutic approaches to these debilitating conditions. …”
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Food taboo practices and associated factors among pregnant women in Sub-Sahara Africa: a systematic review and meta-analysis by Aysheshim Kassahun Belew, Berhanu Mengistu, Ayenew Molla Lakew, Esmeal Ali Muhammad

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The Ethical Challenges of Gamification in Iran: Uncovering the Dark Side by Mona Jami Pour, Hamideh Binaei

“…ObjectiveThe popularity of gamification in business, in areas such as marketing, sales, human resources, and education is growing rapidly. …”
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Lifestyle Interventions Targeting Body Weight Changes during the Menopause Transition: A Systematic Review by Janet Jull, Dawn Stacey, Sarah Beach, Alex Dumas, Irene Strychar, Lee-Anne Ufholz, Stephanie Prince, Joseph Abdulnour, Denis Prud’homme

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Proteomic analysis of murine norovirus-infected Raw 264.7 cells reveals the induction of Ras GTPases by Sung Ho Yun, Md Arif-Ur Rahman, Soo-Bin Nam, Soo Hyeon Kim, Gyuri Kim, Kun Cho, Jong-Soon Choi

“…Abstract The human norovirus (abbreviated as HuNV) is the most common agent responsible for acute viral gastroenteritis. …”
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The Role of Gut Microbiota in Hypertension Management - A Review by Alicja Kot, Marta Wojtczak, Natalia Myśliwiec, Adrian Różycki, Michał Pniak, Paweł Miklis, Maciej Mawlichanów, Aleksandra Ciesielska, Aleksandra Sieradzka, Krzysztof Szerej

“…This comprehensive review explores the intricate relationship between gut microbiota and hypertension, delving into the underlying mechanisms, evidence from animal and human studies, and potential therapeutic interventions. …”
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CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression by Agapitos Patakas, Bochong Li, Naveen K Mehta, Kristan Meetze, Patrick A Baeuerle, Jennifer S Michaelson, Hannah M Findlay, Timothy B London

“…In this setting, we biophysically characterize and report the activities of CLN-978 in cell co-culture assays, multiple mouse models and non-human primates.Results Human T cells redirected by CLN-978 could eliminate target cells expressing less than 300 copies of CD19 on their surface. …”
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Glymphatic dysfunction and neurodegeneration in ALS: Longitudinal insights from rNLS8 TDP-43 mice by Akram Zamani, Adam K. Walker, David K. Wright

“…We found that while glymphatic function normalized to control levels at 7-days post-Dox, AQP4 expression in the cortex was significantly decreased. After 3-weeks of human TDP-43 expression, glymphatic dysfunction, weight loss, neurodegeneration, motor impairments and astrogliosis were observed. …”
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Stress-Induced Changes in the Gastrointestinal Motor System by Victor Plourde

“…Both animal models and human paradigms have been explored. It is acknowledged that stress modulates gastrointestinal (GI) motility through central mechanisms including corticotropin-releasing-factor. …”
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IL-6 Inhibition Reduces STAT3 Activation and Enhances the Antitumor Effect of Carboplatin by Zhi-Yong Wang, Jun-Ai Zhang, Xian-Jin Wu, Yan-Fang Liang, Yuan-Bin Lu, Yu-Chi Gao, You-Chao Dai, Shi-Yan Yu, Yan Jia, Xiao-Xia Fu, Xiaoquan Rao, Jun-Fa Xu, Jixin Zhong

“…Enhanced expression of IL-6 and activation of STAT3 were observed in human colorectal carcinoma samples compared to normal colorectal tissue, with higher levels of IL-6/STAT3 in low grade carcinomas. …”
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A basic study on tree growth and landscape greening in Coastal Urban areas: The case of Hakata port in Fukuoka City, Japan by Maoko Yoshino, Kazuo Asahiro

“…However, growth differences may also be influenced by soil conditions, wind speeds, and human activities. Therefore, further analysis using more detailed physical and chemical surveys, wind conditions, and human use data is needed. …”
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