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5401
Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections
Published 2021“…SARS-CoV-2 directly interacts with angiotensin-converting enzyme 2 (ACE-2) receptors in the human body. Complementary therapies that impact on expression of IgE and IgG antibodies, including administration of bee venom (BV), have efficacy in the management of arthritis, and Parkinson’s disease. …”
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5402
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5403
A systemic analysis of Creutzfeldt Jakob disease cases in Asia
Published 2024-12-01“…Sporadic CJD, which occurs for reasons unbeknown to science (85% of known cases), Genetic or Familial CJD which is characterized by the presence of mutations in the human prion protein (PRNP) gene (10–15% cases) and Iatrogenic CJD that occurs via accidental transmission through medical and surgical procedures (1–2% cases). …”
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5404
Assessment of technogenic pollution by silver compounds on the biological properties of the soil (model experiment)
Published 2024-12-01“… Introduction: Silver (Ag) has increasingly become one of the priority pollutants of soils, which is accompanied by a number of consequences for humans and soil biota. To fully assess the effects of the entry of different chemical forms of Ag into soils, it is necessary to conduct experiments with different types of soils, different exposure periods, as well as a wide range of biological indicators. …”
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5405
Quinoid to benzenoid transition-driven glutathione sensing: Dual-emission carbon dots and smartphone-based ratiometric fluorescence analysis
Published 2025-08-01“…Practical validation using human serum samples demonstrated the method's robustness in complex biological matrices, achieving high recovery rates between 98.5 % and 101.0 %, confirming its suitability for real-world clinical applications. …”
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5406
Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa)
Published 2025-01-01“…The porcine digestive system is physiologically similar to that of humans, making pigs a suitable model for studying DON-induced enterotoxicity. …”
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5407
Detection and Classification of Teacher-Rated Children’s Activity Levels Using Millimeter-Wave Radar and Machine Learning: A Pilot Study in a Real Primary School Environment
Published 2025-01-01“…Traditional assessments of children’s health and behavioral issues primarily rely on subjective evaluation by adult raters, which imposes major costs in time and human resource to the school system. This pilot study investigates the utilization of millimeter-wave radar coupled with machine learning for the objective and semi-automatic detection and classification of children’s activity levels, defined as restlessness, within a real classroom environment. …”
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5408
Whole Genome Sequencing Reveals Substantial Genetic Structure and Evidence of Local Adaptation in Alaskan Red King Crab
Published 2025-01-01“…A long tradition of responsible fisheries management has sustained these species for generations, but modern threats from climate change, habitat loss, and new fishing technologies threaten their ecosystems and the human communities that depend on them. Among these species, Alaska's most charismatic megafaunal invertebrate, the red king crab, faces all three of these threats and has declined substantially in many parts of its distribution. …”
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5409
Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae
Published 2025-02-01“…Background: Angiostrongylus cantonensis is a significant foodborne zoonotic parasite that causes severe neuropathological damage and symptoms in humans. Excretory-secretory products (ESPs) play a pivotal role in elucidating host-parasite interactions and can aid in penetrating host defensive barriers in helminths. …”
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5410
Probe – Integrated electrochemical sensing platform for detection of trace levels of Dapoxetine hydrochloride drug residue in water and drug formulations
Published 2025-04-01“…The extensive use and misuse of selective serotonin reuptake inhibitors (SSRIs) in drug formulations has resulted in their accumulation in food sources and environment, posing noteworthy threats to human health and the global economy. Dapoxetine hydrochloride (DPH) is one of the recent oral drugs frequently misused for the treatment of male sexual dysfunction of premature ejaculation and has lately international attention. …”
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5411
Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro
Published 2024-09-01“…In vitro cytotoxicity of hybrid peptides in human cervical cancer cells lines HeLa and Ca Ski was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”
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5412
KLF5 silencing restrains proliferation, invasion, migration and angiogenesis of gallbladder carcinoma cells by transcriptional regulation of PDGFA
Published 2024-12-01“…Conclusion Collectively, our results suggest that KLF5 regulates GBC cell proliferation, invasion, migration, angiogenesis, as well as apoptosis, via mediating PDGFA transcriptionally, which might provide a novel therapeutic strategy for treatment of human GBC.…”
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5413
A prospective, cross-sectional study to establish age-specific reference intervals for neonates and children in the setting of clinical biochemistry, immunology and haematology: th...
Published 2019-04-01“…Where possible, sample aliquots from the same patients are analysed for an analyte across multiple commercially available analysers.Ethics and dissemination The study protocol was approved by The Royal Children’s Hospital, Melbourne, Ethics in Human Research Committee (34183 A). The study findings will be published in peer-reviewed journals and shared with clinicians, laboratory scientists and laboratories.…”
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5414
Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders
Published 2025-02-01“…Further research has shown that cfDNA is associated with a wide range of human diseases and may have a feedback relationship with inflammation, potentially serving as a non-invasive, accurate, sensitive, and rapid biomarker for clinical applications in disease differential diagnosis, activity monitoring, and prognosis assessment. …”
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5415
Spawning biology, breeding, and larval rearing techniques for Xenentodon cancila (Hamilton) for aquaculture and recreational use in Bangladesh: The first approach
Published 2024-07-01“…Nine doses of common carp pituitary gland (CPG), human chorionic gonadotropin (HCG), and Ovaprim for breeding were administered, except in the control treatment that was without hormones. …”
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5416
Conservation networks do not match the ecological requirements of amphibians
Published 2023-06-01“…Here, we compared the ecological requirements of amphibian species with existing conservation network coverage in a human-dominated region of western France. First, we mapped suitable habitat distributions for nine species of amphibian with varying ecological requirements and mobility. …”
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5417
Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway
Published 2025-02-01“…Using an 8 % high-salt diet model, we evaluated the effects of Kae (200 mg/kg/day) in wild-type (WT) and activating transcription factor 4 (ATF4+/−) knockout mice. Additionally, human aortic endothelial cells (HAECs) cultured under high-salt conditions were used to assess Kae's protective effects, with ATF4 and acyl-CoA synthetase long-chain family member 4 (ACSL4) knocked down via siRNA transfection. …”
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5418
Variability and Source Characterization of Regional PM of Two Urban Areas Dominated by Biomass Burning and Anthropogenic Emission
Published 2022-04-01“…Abstract Identifying the sources and formation pathways of particulate matter (PM) and its components is important to determine the impact of atmospheric aerosols on human health and the warming of the global atmosphere. …”
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5419
The importance of genotyping within the climate-smart plant breeding value chain – integrative tools for genetic enhancement programs
Published 2025-02-01“…Leveraging these technologies can facilitate the development of climate-smart cultivars that adapt effectively to climate variation, meet consumer preferences, and address human and livestock nutritional needs. Most economically important traits in crops are controlled by multiple loci often with recessive alleles. …”
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5420
Taxonomic refinement of Bacillus thuringiensis
Published 2025-02-01“…The bacterium taxonomically belongs to the Bacillus cereus group, which also contains human pathogenic species, e.g., Bacillus anthracis. …”
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