Molecular study of the status of Angiostrongylus cantonensis in rats in Haiti by Fedna Jimmy, Borne Romain, Rieffel Dominique, Bornette Gudrun, Henrys Jean-Hugues, Grenouillet Frédéric, Raoul Francis

“…Angiostrongylus cantonensis, commonly known as the rat lungworm, causes Eosinophilic meningitis in humans. Our study aimed to investigate the prevalence and distribution of this parasite in rats in Haiti. …”
Get full text

Molecular detection of parasites and host preference in wild-caught Culicoides biting midges (Diptera: Ceratopogonidae) in Chiang Mai and Nakhon Si Thammarat Provinces, Thailand by Kyi Soe Baby, Kaewmee Saowalak, Mano Chonlada, Pattanawong Urassaya, Tipparawong Nopporn, Siriyasatien Padet, Gatherer Derek, Urbaniak Michael D., Bates Paul A., Jariyapan Narissara

“…Blood meal analysis revealed that Culicoides primarily fed on cattle (17/29, 58.6%), followed by chickens (10/29, 34.5%), and humans (2/29, 6.9%). Our findings confirmed the existence of several Culicoides species in Thailand, which might be potential vectors for transmission of haemosporidians (Leucocytozoon and Plasmodium). …”
Get full text

Examining rural-urban differences in life satisfaction and its association with health among elderly people in India: Evidence from LASI survey by Nipam Datta, Sushanta Biswas, Dwipen Barman, Bijoy Das, Piyal Basu Roy, Abhijit Sarkar

“…Background: Health-related issues are common phenomena in the human body with increasing age. This study explores the disparities in life satisfaction among the elderly population in rural and urban areas of India and its association with health. …”
Get full text

SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation by Ryan T. Wagner, Ryan A. Hlady, Xiaoyu Pan, Liguo Wang, Sungho Kim, Xia Zhao, Louis Y. El Khoury, Shafiq Shaikh, Jian Zhong, Jeong-Heon Lee, Jolanta Grembecka, Tomasz Cierpicki, Thai H. Ho, Keith D. Robertson

“…Confirmation of this synthetic lethal interaction is performed in isogenic clear cell renal cell carcinoma and immortalized renal epithelial cell lines, in mouse and human backgrounds. Depletion of NSD1 using a CRISPRi targeting approach promotes the loss of SETD2-mutant cells coincident with elevated levels of DNA damage and apoptosis. …”
Get full text

Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin by Jichao Sun, Dinglan Wu, Liuhai Zheng, Huifang Wang, Jihao Zhou, Guangwei Shi, Jingbo Ma, Yuke Jiang, Zhiyu Dong, Jiexuan Li, Yuan-Qiao He, Chengchao Xu, Zhijie Li, Jigang Wang

“…A candidate Nb with high binding affinity to both human and mouse ERp57 was used for constructing CAR-NK cells. …”
Get full text

The Effect of Elevated Basal Follicle Stimulating Hormone Levels on Assisted Reproductive Technology Cycle Outcomes by Inci Kahyaoglu, Hatice Yilmaz Dogru, Sezin Erturk Aksakal, Iskender Kaplanoglu, Serdar Dilbaz, Leyla Mollamahmutoglu

“…Number of follicles ≥17 mm on human chorionic gonadotropin (hCG) day, number of retrieved oocytes, mature oocytes and fertilized oocytes were significantly higher in group I compared to the other groups (p=0.003, p=0.001, p=0.001, and p=0.001, respectively). …”
Get full text

Delineating urban flooding when incorporating community stormwater knowledge by Madeline Scolio, Peleg Kremer, Virginia Smith, Achira Amur, Bridget Wadzuk, Kate Homet, Eric Devlin, Md Abdullah Al Mehedi, Laura Moore

“…Given the complexity of flooding, there is no single method to fully encompass the impacts on both human well-being and the environment. Through the co-creation of flood risk knowledge, community members are empowered and play a critical role in fostering resilience in their neighborhoods. …”
Get full text

Comparative experimental anesthesia efficacy study of epidural injection at the sacrococcygeal space using ultrasound guidance versus blindness technique in Egyptian donkeys (Equus... by Mohamed A. Hamed, Hazem Hamouda, Mohammed Elmetwally, Foad Farrag, Mohamed Abdo Rizk, Mohamed M. A. Abumandour, Yamen Mohammed Hegazy, Alaa Samy

“…In the first group, we used ten cadaver donkeys that were humanely euthanized. In the second group, we used 10 live, healthy adult donkeys to assess the efficacy and time of analgesia onset for blind and ultrasound-guided epidural injections at the sacrococcygeal region. …”
Get full text

Sustainability by extraction of bioactive compounds from onion seeds by Mestour, Selma, Meniai, Abdeslam-Hassen, Melloul, Sarra, Louaer, Mehdi

“…These fatty acids are well known for their benefits for human health. Finally this research showed ability of the supercritical CO2 extraction to induce a sustainability character while being performing in producing bioactive substances, excluding the use of organic solvent and even replacing classical and traditional techniques like hydrodistillation.…”
Get full text

Particulate Pollution in Korhogo and Abidjan (Cote d’Ivoire) during the Dry Season by Sylvain Gnamien, Véronique Yoboué, Cathy Liousse, Money Ossohou, Sékou Keita, Julien Bahino, Silué Siélé, Lamine Diaby

“…Abstract Particulate pollution in West African cities seriously impacts public human health. Assessing the levels of pollution to which populations are exposed is problematic, as to date very few countries in Africa have an air quality monitoring network in place. …”
Get full text

Evaluation of a Novel Water-Based Automated Endoscope Cleaning Process Compared to Conventional Manual Cleaning for Reducing Duodenoscope Contaminatio by Koen van der Ploeg, Juliëtte A. Severin, Margreet C. Vos, Nicole S Erler, Adriana J.C. Bulkmans, Marco Bruno, Bibi C.G.C. Mason-Slingerland

“…Automation in reprocessing may limit human error, reduce the workload, and increase uniformity and traceability. …”
Get full text

Impact of sleep chronotype on blood pressure and metabolic markers by Weiwei Huang, Qinglu Wang, Yuan Gao, Jiefeng Wang, Feihao Wang, Jiyou Tang

“…ObjectiveThe aim of this study was to investigate the correlation between sleep chronotype and metabolic markers to further reveal the influence of sleep chronotype on human health.MethodsThe Morningness-Eveningness Questionnaire was administered to 442 volunteers aged 23–70 years old. …”
Get full text

In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection by Yuta Suzuki, Takayuki Miyazaki, Yoko Ida, Tatsuya Suzuki, Yumi Itoh, Shuto Nakao, Keita Kondo, Kenji Kubara, Keisuke Nishioka, Hiroki Muto, Ryuji Watari, Toshifumi Hirayama, Dai Kakiuchi, Shinya Sato, Satoshi Inoue, Yoshifumi Uemoto, Yohei Mukai, Atsushi Hoshino, Toru Okamoto, Junji Matsui

“…Here, we designed an mRNA encoding an engineered angiotensin-converting enzyme 2 (ACE2) decoy, 3N39v4, composed of high-affinity ACE2 and a human immunoglobulin G Fc domain. The 3N39v4-encoded mRNA was encapsulated in lipid nanoparticles for efficient in vivo delivery. …”
Get full text

Use of linear features by red-legged partridges in an intensive agricultural landscape: implications for landscape management in farmland by Perrot, Charlotte, Seranne, Léo, Berceaux, Antoine, Noël, Mathias, Arroyo, Beatriz, Bacon, Léo

“…Through GPS-monitoring of adult birds, we first assess home range size throughout the year and during the breeding season, in relation to breeding status and to linear features (seminatural linear vegetation and tracks-roads for human traffic) density. Then, we focus on habitat selection during the breeding period in relation to linear features. …”
Get full text

Safe-and-sustainable-by-design redox active molecules for energy storage applications by Clemens Wolf, Janine Maier, Julia Wenger, Georg Rudelstorfer, Christian Leypold, Julia Voglhuber-Höller, Matiss Reinfelds, Andrea Weiner, Arantza Muriana, Susanne Lux, Claudia Mair-Bauernfeind, Andreas Falk, Stefan Spirk

“…Conclusion Taken together, the modified designs led to safer and more sustainable redox active materials for both humans and the environment at lab scale. Implementing the results mentioned above to further expedite the technology will ultimately pave the way to more sustainable energy storage applications. …”
Get full text

Evaluating the Performance of Low-cost PM Sensors over Multiple COALESCE Network Sites by Vishal R. Dharaiya, Vasudev Malyan, Vikas Kumar, Manoranjan Sahu, Chandra Venkatraman, Pratim Biswas, Kajal Yadav, Diksha Haswani, Ramya Sunder Raman, Ruqia Bhat, Tanveer Ahmad Najar, Arshid Jehangir, Rohit P. Patil, G. Pandithurai, Sandeep Singh Duhan, Jitendra Singh Laura

“…Abstract Air quality is a global concern, with particulate matter receiving considerable attention due to its impact on human health and climate change. Recent advances in low-cost sensors allow their deployment in large number to measure spatio-temporal and real-time air quality data. …”
Get full text

An investigator-blinded, 24-month, parallel-group, non-inferiority study to compare aesthetic restorations in primary anterior teeth in a paediatric dental clinic: study protocol f... by Ana Paula Taboada Sobral, Elaine Marcilio Santos, Marcela Leticia Leal Gonçalves, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Elza Padilha Ferri, Juliana Maria Altavista Sagretti Gallo, Thais Gimenez, José Carlos Pettorossi Imparato

“…Secondary outcomes will include tooth survival, longevity of restoration, quality of life, perception and satisfaction of the participants’ parents/guardians.Ethics and dissemination This protocol has been approved by the Human Research Ethics Committee of Universidade Metropolitana de Santos (protocol number: 6.019.297. …”
Get full text

Characteristics and Sources of Organic Aerosol Markers in PM2.5 by Zheng Li, Ruiwen Zhou, Yuanyuan Li, Min Chen, Yachen Wang, Tonglin Huang, Yanan Yi, Zhanfang Hou, Jingjing Meng, Li Yan

“…These results confirmed that biomass burning can significantly influence the concentrations and chemical compositions of OAs, thereby they can affect human health and atmospheric chemistry.…”
Get full text

MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis by Junpei Kawamura, Munekazu Yamakuchi, Kentaro Ueno, Teruto Hashiguchi, Yasuhiro Okamoto

“…In addition, we investigated the tube formation, migration, and proliferation of human lung microvascular endothelial cells (HMVEC-L) transfected with miR-25-3p mimic, miR-25-3p inhibitor, or PHLPP2 small interfering RNA, and examined HIF-1α/VEGF-A signaling after hypoxic stimulation. …”
Get full text

Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter by Parveen Goyal, KanagaVijayan Dhanabalan, Mariafrancesca Scalise, Rosmarie Friemann, Cesare Indiveri, Renwick CJ Dobson, Kutti R Vinothkumar, Subramanian Ramaswamy

“…N -Acetylneuraminic acid (Neu5Ac) is a negatively charged nine-carbon amino sugar that is often the peripheral sugar in human cell-surface glycoconjugates. Some bacteria scavenge, import, and metabolize Neu5Ac or redeploy it on their cell surfaces for immune evasion. …”
Get full text