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A Systematic Review on Poisoned Patients as Potential Organ Donors
Published 2024-12-01“…Studies lacking patient data or involving non-human research were excluded. To assess the risk of bias and quality of the included studies, the Joanna Briggs Institute Critical Appraisal Checklists and the Newcastle-Ottawa Scale were used. …”
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Infection‐Related Hospitalization and Incident Heart Failure: The Atherosclerosis Risk in Communities Study
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Automated Video Assistant Referee in Lead Climbing
Published 2025-01-01“…., & Choi, J.-H. (2023). Human pose estimation using MediaPipe pose and optimization method based on a humanoid model. …”
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Development and optimization of a new competitive ELISA using recombinant (rPSA D15 and rCag11) antigens for the detection of Helicobacter pylori infection.
Published 2025-01-01“…H. pylori (Hp) is highly causative agent of chronic gastritis, gastric cancer and human death worldwide. To address the challenge of H. pylori infection, numerous immunological assays have been developed for its diagnosis and management. …”
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Evaluation of wheat products with high flavonoid content: justification of importance of marker-assisted development and production of flavonoid-rich wheat cultivars
Published 2017-11-01“…The creation of varieties with a high content of flavonoids (plant compounds that can have a positive effect on human health) is one of the important directions of plant breeding oriented on the functional foods development. …”
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Pengaruh Masase pada Punggung Terhadap Intensitas Nyeri Kala I Fase Laten Persalinan Normal Melalui Peningkatan Kadar Endorfin
Published 2015-01-01“…Intensitas nyeri dinilai dengan kuisioner dan kadar endorfin diukur dengan human beta endorfin Elisa Kit. Data dianalisis menggunakan uji t-test independent dan korelasi Spearmen. …”
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De la police coloniale française à la police nationale marocaine : décolonisation et héritages policiers (1953-1960)
Published 2023-12-01“…The police continuities, which unfold across various institutional, doctrinal, and human levels, seem astonishing, given the central role the Cherifian Police played in maintaining colonial order and harshly repression independence movements.This article delves into the institutional history of the police in Morocco from August 1953, when the exile of Sultan Mohammed V triggered a wave of nationalist violence that severely tested the colonial police, to the year 1960, when the privileged connection with France was questioned by the Moroccan regime on all fronts, including within the police. …”
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Influence of ethnicity on cyclin-dependent kinase inhibitor efficacy and toxicity: A systematic review and meta-analysis
Published 2025-02-01“…Background: The combination of cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) with endocrine therapy (ET) is the standard of care for patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (aBC). …”
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Microcephaly protein ANKLE2 promotes Zika virus replication
Published 2025-02-01“…We observe that ANKLE2 localization is drastically shifted to sites of NS4A accumulation during infection and that knockout of ANKLE2 reduces ZIKV replication in multiple human cell lines. This decrease in virus replication is coupled with a moderate increase in innate immune activation. …”
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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity
Published 2021-10-01“…However, shedding or downregulation of NKG2D ligands (NKG2DL) can prevent NKG2D activation, resulting in escape of cancer cells from NKG2D-dependent immune surveillance.Methods To enable tumor-specific targeting of NKG2D-expressing effector cells independent of membrane-anchored NKG2DLs, we generated a homodimeric recombinant antibody which harbors an N-terminal single-chain fragment variable (scFv) antibody domain for binding to NKG2D, linked via a human IgG4 Fc region to a second C-terminal scFv antibody domain for recognition of the tumor-associated antigen ErbB2 (HER2). …”
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Improvement in XIa Selectivity of Snake Venom Peptide Analogue BF9-N17K Using P2′ Amino Acid Replacements
Published 2025-01-01“…The anticoagulation assay showed that the four P2′ single-point mutants still had apparent inhibitory anticoagulation activity that selectively inhibited the human intrinsic coagulation pathway and had no influence on the extrinsic coagulation pathway or common coagulation pathway, which indicated that the single-point mutants had minimal effects on the anticoagulation activity of BF9-N17K. …”
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New pneumococcal serotype 20C is a WciG O-acetyltransferase deficient variant of canonical serotype 20B
Published 2025-01-01“…Consequently, genome-based serotyping/bioinformatic tools must scrutinize all cps genes for mutations that might inactivate/modify cps-encoded enzymes, ensuring effective tracking of emerging capsule variants in response to ongoing vaccination efforts.IMPORTANCEStreptococcus pneumoniae (pneumococcus) is a significant human pathogen known for producing a wide array of antigenically and structurally diverse capsule types, a fact that poses a serious challenge to the effectiveness of vaccines targeting pneumococcal capsule polysaccharide (PS). …”
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MathVision: An Accessible Intelligent Agent for Visually Impaired People to Understand Mathematical Equations
Published 2025-01-01“…The LSTM architecture, chosen for its effectiveness with sequential data, is trained on a dataset containing paired examples of equations and corresponding human-generated descriptions. Fine-tuning includes optimizing hyperparameters for the task, and evaluation metrics such as the BLEU score are used to assess the model’s performance in generating accurate and contextually relevant textual representations for the detected mathematical content. …”
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Effects of 24 Weeks of Growth Hormone Treatment on Bone Microstructure and Volumetric Bone Density in Patients with Childhood-Onset Adult GH Deficiency
Published 2020-01-01“…Effects of recombinant human growth hormone (rhGH) on bone microarchitecture in CO AGHD were insufficiently evaluated. …”
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MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy
Published 2025-02-01“…Methods The in vitro studies included the effects of DSS duration on MSCs, and the characterization of DSS-Exo and Exo, followed by the assessment of RNA and protein expression levels of peritoneal fibrosis markers and inflammatory cytokines levels after treating human peritoneal mesothelial (HMrSV5) cells. In vivo experiments were conducted on a PF mouse model to observe cell morphology, collagen deposition, fibrosis localization, and to evaluate peritoneal functions such as filtration rate, urea nitrogen clearance, peritoneal thickness, and protein leakage. …”
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