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32461
Climate change as a wildlife health threat: a scoping review
Published 2025-02-01“…Amongst the subset of papers focused on vector distribution, top themes included concepts related to pathogen transmission dynamics, human/public health, and pathogen prevalence, while health papers focused on concepts related to increasing temperatures, species home ranges and distribution, and changing environmental variables. …”
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32462
Estimation of median LC50 and toxicity of environmentally relevant concentrations of thiram in Labeo rohita
Published 2025-02-01“…The findings demonstrate that thiram severely pollute the marine eco-system and is quite hazardous for aquatic species by causing severe health effects even at sub-lethal concentrations and thus, render the apparently clean water to be unfit for animal and human consumption.…”
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32463
Chronic and infectious respiratory mortality and short-term exposures to four types of pollen taxa in older adults in Michigan, 2006-2017
Published 2025-01-01“…Methods We obtained records for all Michigan deaths from 2006-2017 from the Michigan Department of Health and Human Services (MDHHS). Deaths from infectious and chronic respiratory-related causes were selected using International Classification of Diseases (ICD-10) codes. …”
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32464
Synthetic inhibition of SREBP2 and the mevalonate pathway blocks rhabdomyosarcoma tumor growth in vitro and in vivo and promotes chemosensitization
Published 2025-02-01“…Results: In silico analysis showed upregulation of sterol regulatory element-binding protein 2 (SREBP2) and MVP genes, including 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR), farnesyl-diphosphate synthase (FDPS), squalene epoxidase (SQLE), which correlated with worse overall patient survival. Targeting of MVP in human RD and RH30 lines by inhibitors of SREBP2 (fatostatin), HMGCR (lovastatin and simvastatin), and FDPS (zoledronic acid) resulted in impaired cell growth, migration, and viability, and increased oxidative cell death in combination with actinomycin D. …”
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32465
Hydrothermal synthesis of a nickel-oxide-infused orange peel nanobiocomposite for enhanced heavy metal removal from mining wastewater
Published 2025-06-01“…Heavy metals in various geochemical forms, such as exchangeable ions, carbonates, and oxides, pose significant risks to human health and the environment due to their persistence and bioaccumulation. …”
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32466
Development and progression association of various ophthalmic pathologies with the gut microbiome state (literature review)
Published 2023-11-01“…Modern researches focus on studying the effect of changes in the gut microbiome on human health, including his eyes. This suggests the potential use of this indicator as a non-invasive biomarker during differential diagnosis, as well as its introduction for ophthalmic therapy purposes. …”
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32467
The current state of knowledge on the role of NKG2D ligands in multiple sclerosis and other autoimmune diseases
Published 2025-01-01“…The activating receptor belonging to the NKG2D is stimulated by specific ligands: in humans these are major histocompatibility complex (MHC) class I polypeptide–related sequence A (MICA) and MHC class I polypeptide-related sequence B (MICB) proteins and UL16 binding 1–6 proteins (ULBP1-6). …”
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32468
First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale
Published 2023-01-01“…The genetic potential to synthesize human-dangerous mycotoxins (fumonisin, ochratoxin B, aflatoxin, and gliotoxin) has been revealed for M. nivale. …”
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32469
Investigation of the spatial and temporal long-term hydro-climatic trends in Upper Omo Gibe Basin, Ethiopia
Published 2025-02-01“…Human activities have changed hydroclimatic components worldwide, affecting agricultural productivity and water resources management. …”
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32470
Vulnerability, Resilience and Adaptation of Lagos Coastal Communities to Flooding
Published 2024-12-01“…Surviving in flood-prone cities like Lagos is a daunting task because flood affects livelihood, human health, and can even cause death. Specifically, the 2020 flood incidence in Nigeria affected about 40% of the local government areas, and 97% of the states, displacing over 120,000 persons and killing 68 persons aside from properties and farmlands destroyed. …”
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32471
Double degree programs and education for sustainable development implementation: Experience of Ukrainian and UK universities cooperation in wartime
Published 2025-02-01“…Ukrainian HEIs have been significantly losing their capacity for development. Loss of human capital, including educational losses, becomes more relevant from the perspective of further sector development.This paper explores the intersection of DDP implementation and the implementation of Education for Sustainable Development (ESD), focusing on faculty members’ experiences within the Twinning Initiative framework. …”
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32472
Syrian refugee and diaspora healthcare professionals: Case studies from the eastern mediterranean and European regions
Published 2025-01-01“…Initially, many stayed in the eastern mediterranean region; however, as the conflict became increasingly protracted and employment policies for Healthcare Professionals (HCPs) became increasingly restrictive, some moved elsewhere, particularly to Germany and the United Kingdom, both of which have aimed to capitalise on both refugee and diaspora HCPs to support human resources gaps in their health systems. Our aim is to explore the different policy practices towards Syrian refugee and diaspora HCPs in the eastern mediterranean and European regions. …”
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32473
Evaluation of the resistome and gut microbiome composition of hospitalized patients in a health unit of southern Brazil coming from a high animal husbandry production region
Published 2025-01-01“…The One Health approach, which integrates human, animal, and environmental health, highlights the roles of agricultural and hospital settings in the propagation of AMR. …”
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32474
Direct and indirect effects of land use on microbiomes of trap-nesting solitary bee larvae and nests
Published 2025-01-01“…IntroductionThe global decline in biodiversity and insect populations highlights the urgent need to conserve ecosystem functions, such as plant pollination by solitary bees. Human activities, particularly agricultural intensification, pose significant threats to these essential services. …”
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32475
Evaluation of the Level of Salivary sHLA-G in Children Aged 3–5 Years with or without Dental Caries
Published 2020-01-01“…As dental caries is a bacterial infectious disease, the host immune system parameters including soluble human leukocyte antigen-G (sHLA-G) are essential factors in estimating dental caries. …”
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32476
Space-time Characteristics of 16 PM2.5-bound Phthalates (PAEs) in Ambient Air from Shanghai: Profiles, Sources, Meteorological Effects, and Exposure Risks
Published 2023-08-01“…They occur in both particle and gas phases in the air causing threats to human health. In the study in hands, LC-MS/MS was employed for the analysis of PM2.5-PAEs in 128 ambient PM2.5 samples from nine locations (urban, sub-urban and coastal) in Shanghai between February 2015 and September 2021. …”
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32477
Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment
Published 2019-06-01“…Exploratory outcomes include several environmental as well as personality factors associated with OUD and with propensity to demonstrate a placebo effect.Ethics and dissemination Human subjects oversight for this study is provided by the University of Maryland, Baltimore and University of Maryland, College Park Institutional Review Boards. …”
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32478
Detection of Invasive Species (Siam Weed) Using Drone-Based Imaging and YOLO Deep Learning Model
Published 2025-01-01“…The study demonstrates the feasibility of using YOLO models to detect invasive species in natural landscapes, providing a safe alternative to the current method involving human spotters in helicopters. Future research will focus on developing tools to merge duplicates, gather georeference data, and report detections from large image datasets more efficiently, providing valuable insights for practical applications in environmental management at the catchment scale.…”
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32479
Phenolic Content and Antioxidant and Antimicrobial Activities of Malva sylvestris L., Malva oxyloba Boiss., Malva parviflora L., and Malva aegyptia L. Leaves Extract
Published 2021-01-01“…As such, it is emerging as a promising therapeutic agent for the treatment of various neurodegenerative diseases and many types of human infectious diseases.…”
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32480
-Tyrosine Confers Residualizing Properties to a -Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies
Published 2016-06-01“…The radiochemical purities, antigen-expressing U87MG.de2-7 human glioblastoma cell-binding properties, and targeting of xenografts at 72 hours post injection of all radioconjugates were compared. …”
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