Analysis of factors influencing HPV vaccination intention among Chinese college students: structural equation modeling based on health belief theory by Shi-Yuan Song, Ying Guo, Yi-Hua Li, Zheng Wang, Wei Gao

“…BackgroundIncreasing human papillomavirus (HPV) vaccination rates is vital for achieving society-wide public health goals, yet current research on HPV vaccine-related knowledge, vaccination intentions, and behaviors among college students in ethnic minority regions is inadequate. …”
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Characterization of demethylating DNA glycosylase ROS1 from Nicotiana tabacum L. by D. V. Petrova, N. V. Permyakova, I. R. Grin, D. O. Zharkov

“…Expression of the NtROS1 gene in cultured human cells resulted in a global decrease in the level of genomic DNA methylation. …”
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Pre-pandemic cross-reactive antibody and cellular responses against SARS-CoV-2 among female sex workers in Dakar, Senegal by Bobby Brooke Herrera, Bobby Brooke Herrera, Bobby Brooke Herrera, Bobby Brooke Herrera, Beth Chaplin, Souleymane MBoup, Adam Abdullahi, Adam Abdullahi, Michelle He, Sydney M. Fisher, Sulaimon Akanmu, Charlotte A. Chang, Donald J. Hamel, Ravindra K. Gupta, Ravindra K. Gupta, Phyllis J. Kanki

“…We investigated the potential role of pre-existing immunity in shaping the epidemiology of COVID-19 in Africa.MethodsPlasma collected from Senegalese female sex workers prior to the COVID-19 pandemic was screened for SARS-CoV-2 and human coronavirus (hCoV) antibodies by virion immunoblots. …”
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Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults by Yuankang Zhu, Zhenlin Yang, Yuhao Chen, Lingzi Qian, Changning Hao, Liangshi Hao, Boshen Yang, Junli Duan

“…However, whether glyphosate exposure influences human cardiovascular health at the population levels remains unknown. …”
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Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer by QingShui Wang, ShuYun Weng, WenTing Zhong, YouYu Lin, Yan Yu, YiMin Huang, LiLin Ge, XiuLi Zhang, FangQin Xue, Yehuda G. Assaraf, Yao Lin

“…Abstract Background Death-Associated Protein Kinase 1 (DAPK1) family members are calcium/calmodulin-regulated serine/threonine kinases implicated in cell death, normal development, and human diseases. However, the regulation of DAPK1 expression in cancer remains unclear. …”
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Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy by Gregory B. Lesinski, Chrystal M. Paulos, Maggie Phillips, Jacklyn Hammons, Isaac Karpovsky, Zaid Mahdi, Natalie K. Horvat, Megan M. Wyatt, Margaret A. Hall, Cameron J. Herting, Richard A. Moffitt

“…Currently, genetically engineered mouse models (GEMMs) for PDAC are considered a “gold-standard” as they recapitulate many aspects of human disease. However, these models have limitations, including marked tumor variability across individual mice and the cost of colony maintenance.Methods Using flow cytometry and immunohistochemistry, we characterized the immunological features and trafficking patterns of adoptively transferred T cells in orthotopic PDAC (C57BL/6) models using two mouse cell lines, KPC-Luc and MT-5, isolated from C57BL/6 KPC-GEMM (KrasLSL-G12D/+p53−/− and KrasLSL-G12D/+p53LSL-R172H/+, respectively).Results The MT-5 orthotopic model best recapitulates the cellular and stromal features of the TME in the PDAC GEMM. …”
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Impact of intermediate-dose tertiary prophylaxis on quality of life and psychological aspects of adult patients with severe/moderate hemophilia A by Hua Gao, Jia Liu, Shiqiu Zhou, Jing Gao, Jing Tan, Rong Chen

“…This research aims to explore the impact of intermediate-dose tertiary prophylaxis with recombinant human FVIII (rhFVIII) on quality of life, anxiety and depression in such individuals transitioned from on-demand treatment.Methods This retrospective analysis collected data from July 2019 to July 2022. …”
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Nucleotide receptor P2X7/STAT6 pathway regulates macrophage M2 polarization and its application in CAR-T immunotherapy by Qin Si, Lu Yang, Jie Liu, Hui Liu, Ruifang Bu, Na Cui

“…This investigation scrutinizes whether silencing of P2X7 receptor within macrophages could lead to augmented anti-tumor potency of CAR-T. Method: Human peripheral blood mononuclear cells were artificially differentiated into macrophages or M2 macrophage in vitro. …”
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Evolutionary determinants of reproductive seasonality: A theoretical approach by Burtschell, Lugdiwine, Dezeure, Jules, Huchard, Elise, Godelle, Bernard

“…Overall, this study contributes a powerful theoretical framework and modelling tool that may apply across the life-history space, as well as sheds new light on the emergence and maintenance of non-seasonal breeding in slow-living species, including humans. …”
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Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro by Paulina Kobylka, Pawel Bakun, Joanna Kuzminska, Tomasz Goslinski, Marek Murias, Malgorzata Kucinska

“…This study tested curcumin derivatives with modified feruloyl moieties (<b>2a</b> and <b>2a-B</b>) and the β-diketo moiety (<b>2a-B</b>) to better understand their anticancer mechanism against human bladder cancer cells. The anticancer activity of <b>2a</b> and <b>2a-B</b> was determined using MTT (hypoxic conditions) and LDH (normoxic conditions) assays. …”
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Collecting perspectives on project prioritisation process in the EU co-funded multinational partnership for the assessment of risks from chemicals (PARC) through focus group discus... by Katya Manuella Permana, Maria Tannous, Hanna Mouaziz, Pascal Sanders, Nathalie Bonvallot, Christophe Rousselle

“…Abstract Introduction The European Partnership for the Assessment of Risks from Chemicals (PARC) is a 7-year multinational partnership aimed at consolidating and strengthening European Union’s (EU) research and innovation capacity for chemical risk assessment (RA) to protect human health and the environment. It consists of nine work packages (WP) involving more than 200 participating organisations from 29 countries. …”
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The regulatory role of cystatin C in autophagy and neurodegeneration by T. A. Korolenko, A. B. Shintyapina, A. B. Pupyshev, A. A. Akopyan, G. S. Russkikh, M. A. Dikovskaya, V. A. Vavilin, E. L Zavjalov, M. A. Tikhonova, T. G. Amstislavskaya

“…The aim: to study the role of cystatin C in neurodegeneration and evaluate the results in relation to the mechanism of autophagy. In our study on humans, a higher concentration of cystatin C was noted in cerebrospinal fluid than in serum; much lower concentrations were observed in other biological fluids (intraocular fluid, bile, and sweat). …”
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Evaluation of the impact of PEPFAR transition on retention in care in South Africa’s Western Cape Province by J Chiliza, R Laing, F G Feeley, A T Brennan

“…We observed no RIC difference by facility size and a slight increase when two or more human resources transitioned from PEPFAR to the government. …”
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Psychoeducation of higher education seekers with using of the resource-oriented model of stress resiliency in war conditions by V.V. Ogorenko, A.E. Nikolenko, T.Y. Shusterman, V.O. Kokashynskyi, A.B. Khotimska, M.H. Koren

“…The «BASIC Ph» model of stress resiliency was utilized as a framework for determining optimal human resource utilization during crises, with six modalities forming individual style of resiliency. …”
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Collaborative Governance in the Digital Transformation Age: A Systematic Literature Review with Bibliometric Mapping by Rio Yusri Maulana, Mitja Dečman

“…As societies increasingly rely on digital platforms and online communication, the prime urge and necessity of the human race – i.e., to communicate and collaborate in tackling these challenges – puts collaborative governance in digital transformation high on the agenda of governments, the private sector, and citizens. …”
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Association between metabolic score for visceral fat index and BMI-adjusted skeletal muscle mass index in American adults by Yifan Zhou, Xiangjie Su, Haitao Tan, Jun Xiao

“…Both obesity and the reduction of muscle mass can significantly affect human health. However, research exploring the relationship between METS-VF and SMI remains limited. …”
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miR-576-5p Promotes the Proliferation of Papillary Thyroid Carcinoma through the MAPK4-AKT Pathway by Rui Hai, Yang Zhou, Fan Li, Qingxi Guo, Yang Long, Fang Wang, Lian Cheng, Fei Wu, Shi Chen, Xiangyu Zhou

“…MicroRNA-576-5p (miR-576-5p) plays an important role in different human cancers. However, the biological function of miR-576-5p in papillary thyroid carcinoma (PTC) is still unclear. …”
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Relationship between meteorological factors and the incidence of severe fever with thrombocytopenia syndrome: a systematic review and meta-analysis by Guangju Mo, Hongmei Zhu, Jing Li, Huaiping Zhu, Qiyong Liu

“…Future studies on the relationship between meteorological factors and the incidence of SFTS should fully consider human activities and environmental factors, and explore the pathogenesis and transmission mechanisms in greater depth, so as to provide targeted preventive measures. …”
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Exploring salivary gene expression clusters: A bioinformatics approach for advanced diagnosis and prognosis in head and neck squamous cell carcinoma by Rajesh Parsanathan, Rishaba Byju, D.S. Prabakaran

“…Materials and methods: A comprehensive keyword search was conducted to extract 74 salivary gland secretion genes from the Human Protein Atlas. GeneMANIA and STRING databases were employed to analyse protein-protein interactions and predict functional partners. …”
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Role of Subsurface Geo-Energy Pilot and Demonstration Sites in Delivering Net Zero by M. H. Stephenson, D. A. C. Manning, M. J. Spence, L. Stalker, Z. K. Shipton, A. A. Monaghan

“…Gaps were identified in two areas: 1) test facilities to aid the design of low cost, high resolution, unobtrusive seismic and other monitoring for a seismically noisy urban environment with a sensitive human population, for example for ATES in urban areas; and 2) a dedicated through-fault zone test site to understand fault transmissivity and reactivation. …”
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