Leveraging Social Media Data for Forest Fires Sentiment Classification: A Data-Driven Method by Warih Maharani, Hanita Daud, Noryanti Muhammad, Evizal Abdul Kadir

“…Background: The rise in forest fires over the last two years, which is due to rise in dry weather conditions and human activities, have greatly impacted an area of 1.6 million hectares, leading to significant ecological, economic, and health issues, hence the need to improve disaster response strategies. …”
Get full text

The comprehensive assessment of epigenetics changes during skin development by Li Lei, Ling Jiang, Yibo Hu, Menglu Chen, Jinhua Huang, Jing Chen, Qinghai Zeng

“…The transcriptomes of human skin samples from different ages or irradiated with different types and doses of UV light were analyzed using R (version 4.0.3) software. …”
Get full text

Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

“…In addition, the effect of CEMIP on tumor growth and the antitumor efficacy of targeting CEMIP in combination with ICB therapy were evaluated in murine models of colorectal cancer.Results We reported that CEMIP specifically downregulated the expression of MHC-I on the surface of murine and human colon cancer cells, hindering the cytotoxicity of CD8+ T cells. …”
Get full text

Under a not so white sky: visual impacts of stratospheric aerosol injection by Ansar Lemon, David W Keith, Steve Albers

“…We compare the simulated changes in color and brightness to experimental measurements of minimum thresholds humans can detect. The three aerosol types cause similar changes, except most notably the diamond aerosol increases brightness of the solar aureole by roughly three to five times less than do H _2 SO _4 or CaCO _3 . …”
Get full text

“Old” and “New” Trust in Higher Education by P. A. Ambarova, G. E. Zborovsky, N. V. Shabrova

“…They are important to design various academic practical experience oriented on the use of resource properties of trust with a view to developing the social and human capital of high school communities as well as to elaborate new social technologies for managing the processes of trust formation in the university.…”
Get full text

Comparative efficacy of repurposed drugs lopinavir-ritonavir and darunavir-ritonavir in hospitalised COVID-19 patients: insights from a tertiary centre cohort by Dóra Paróczai, Dóra Paróczai, András Bikov, András Bikov, Andreea Blidaru, Emanuel Bobu, Ana Lascu, Ana Lascu, Cristian Ion Mot, Cristian Ion Mot, Stefan Mihaicuta, Stefan Mihaicuta, Stefan Frent, Stefan Frent

“…Although lopinavir-ritonavir (LPV/r) and darunavir-ritonavir (DRV/r) have shown in vitro efficacy against COVID-19, the results in human studies have been inconsistent. Therefore, our objective was to compare the efficacy of LPV/r and DRV/r in COVID-19 patients admitted to a tertiary centre in Romania.Research design and methodsA clinical dataset from 417 hospitalised patients was analysed. …”
Get full text

High Glucose with Insulin Induces Cell Cycle Progression and Activation of Oncogenic Signaling of Bladder Epithelial Cells Cotreated with Metformin and Pioglitazone by Daejin Kim, Byul-Nim Ahn, YeongSeok Kim, Dae Young Hur, Jae Wook Yang, Ga Bin Park, Jung Eun Jang, Eun Ju Lee, Min Jeong Kwon, Tae Nyun Kim, Mi Kyung Kim, Jeong Hyun Park, Byoung Doo Rhee, Soon Hee Lee

“…The cells derived from human bladder epithelial cells (HBlEpCs) were treated with metformin or pioglitazone with high glucose and insulin. …”
Get full text

Toxicity, antifeedant and repellent activities of five essential oils on adult Cassida vittata Vill. (Coleoptera: Chrysomelidae) by Achraf Charkaoui, Rachid Jbilou, Houssam Annaz, Kacem Rharrabe

“…Chemical pesticides are considered the most common strategy to control this pest, and their use is extremely harmful to human health and the environment. In this context, the adults of C. vittata were exposed to five essential oils (EOs) obtained from: Artemisia herba alba Asso. …”
Get full text

Bradykinin B1 receptor signaling triggers complement activation on endothelial cells by Ingrid Lopatko Fagerström, Alexandra Gerogianni, Markus Wendler, Ida Arvidsson, Ashmita Tontanahal, Ann-Charlotte Kristoffersson, Fatimunnisa Qadri, Michael Bader, Michael Bader, Michael Bader, Michael Bader, Michael Bader, Diana Karpman

“…This study investigated if KKS activation induced complement activation on endothelial cells, and if activation was dependent on bradykinin B1 receptor (B1R) signaling.MethodsKKS was activated in normal human serum by kaolin or activated factor XII (FXIIa). …”
Get full text

Screening for schistosomiasis in a non-endemic setting: Accuracy of a rapid antibody test using finger prick blood by Margherita Ortalli, Bianca Granozzi, Michele Bacchiega, Concettina Di Lillo, Greta Roncarati, Silvia Stefania Longoni, Cristina Mazzi, Elisa Vanino, Zeno Bisoffi, Stefania Varani

“…Human schistosomiasis is a chronic neglected tropical disease caused by blood flukes of the genus Schistosoma, infecting 250 million people worldwide, mostly in sub-Saharan Africa. …”
Get full text

Complete Genome Sequence of Photobacterium damselae Subsp. damselae Strain SSPD1601 Isolated from Deep-Sea Cage-Cultured Sebastes schlegelii with Septic Skin Ulcer by Yongxiang Yu, Zheng Zhang, Yingeng Wang, Meijie Liao, Xiaojun Rong, Bin Li, Kai Wang, Jing Chen, Hao Zhang

“…Photobacterium damselae subsp. damselae (PDD) is a Gram-negative bacterium that can infect a variety of aquatic organisms and humans. Based on an epidemiological investigation conducted over the past 3 years, PDD is one of the most important pathogens causing septic skin ulcer in deep-sea cage-cultured Sebastes schlegelii in the Huang-Bohai Sea area and present throughout the year with high abundance. …”
Get full text

Design and assembly of plant-based COVID-19 candidate vaccines: reсent development and future prospects by E. A. Uvarova, P. A. Belavin, E. V. Deineko

“…This variant of the virus is characterized by a high degree of variability and, as the current situation with its spread across different regions of the globe shows, it can lead to a progressive spread of infection among the human population and become the cause of a pandemic. …”
Get full text

Middle East respiratory syndrome coronavirus (MERS-CoV) internalization does not rely on DPP4 cytoplasmic tail signaling by Karthika Thankamani, Divakar Shubham, Gayatri Kandpal, Ann Mary Isaac, Modenkattil Sethumadhavan Kavitha, V. Stalin Raj

“…Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) infects respiratory epithelial cells in humans and camels by binding to dipeptidyl peptidase 4 (DPP4) as its entry receptor. …”
Get full text

Comparative Effects of Crocin and Losartan on RAGE, TGF‐β, TNF‐α Gene Expression and Histopathological Changes of the Liver Tissue in Rats With Diabetes by Shahnaz Rajabi, Yaser Mohammadi, Hamid Kabiri‐rad, Mahdiyeh Rajabi‐moghaddam, Azam Rezaei Farimani

“…Conclusion Crocin may be a feasible therapeutic agent for treating diabetes and its symptoms when combined with pharmaceutical medications. Human research is still needed to reach clear conclusions.…”
Get full text

Cowpea cropping systems, traits preference and production constraints in the upper west region of Ghana: farmers' consultation and implications for breeding by Benjamin Karikari, Margaret Delle Maale, Ebenezer Anning, Daniel Brain Akakpo, Afishata Mohammed Abujaja, Isaac Kwahene Addai

“…Walp) is used primarily as food for humans and feed for animals. It is also used for soil management within a cropping system. …”
Get full text

Marker-assisted breeding of hybrid lines of <i>Triticum dicoccon</i> (Schrank) Schuebl. × <i>Triticum aethiopicum</i> Jakubz. with purple grain by P. I. Stepochkin, E. I. Gordeeva, Е. K. Khlestkina

“…Cereals whose grain contains antioxidants salutary for human health are promising for functional nutrition. …”
Get full text

Development of a non-specialist worker delivered psychological intervention to address alcohol use disorders and psychological distress among conflict-affected populations in Ugand... by Abhijit Nadkarni, Alessandro Massazza, Wietse A. Tol, Sergiy Bogdanov, Lena S. Andersen, Quincy Moore, Bayard Roberts, Helen A. Weiss, Soumya Singh, Melissa Neuman, Carl May, Daniela C. Fuhr

“…A key barrier to care is the lack of contextually relevant interventions and adequately skilled human resources to deliver them. This paper describes the systematic development of the CHANGE intervention, a potentially scalable psychological intervention for people with co-existing AUD and psychological distress in conflict-affected populations, delivered by non-specialist workers (NSWs). …”
Get full text

GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axis by Wen-Ke Wang, Hui-Yu Lin, Che-Hsuan Lin, Hsun-Hua Lee, Yen-Lin Chen, Yu-Hsien Kent Lin, Hui-Wen Chiu, Shry-Ming Sheen-Chen, Yuan-Feng Lin

“…RT-PCR assays were used to test the GRK6 expression in human BC tissues and cell lines. The in vitro cellular migration and in vivo lung colony-forming assays were established to estimate the metastatic potentials of TNBC cells. …”
Get full text

Digital intervention promoting physical activity among obese people (DIPPAO) randomised controlled trial: study protocol by Bruno Pereira, Martine Duclos, Alexandre Mazéas, Aïna Chalabaev, Marine Blond

“…A mixed-model approach will be used to analyse the change in outcomes over time.Ethics and dissemination The research protocol has been reviewed and approved by the Local Human Protection Committee (CPP Ile de France XI, No 21 004-65219). …”
Get full text

Biogenic Amines and Aflatoxins in Some Imported Meat Products: Incidence, Occurrence, and Public Health Impacts by Fahad Dhafer Algahtani, Alaa Eldin Morshdy, Mohamed A. Hussein, Essam Said Abouelkheir, Adeniyi Adeboye, Andrea Valentine, Mohamed Tharwat Elabbasy

“…Since the beginning of humanity, the global burden of foodborne disease has had a decimating effect on populations, with biogenic amines (BAs) and aflatoxins in meat products implicated. …”
Get full text