miR-223 and Chromogranin A Affect Inflammatory Immune Cell Activation in Liver Metastasis of Neuroendocrine Neoplasms by Lukas Geisler, Katharina Detjen, Teresa Hellberg, Marlene Kohlhepp, Carsten Grötzinger, Jana Knorr, Ines Eichhorn, Raphael Mohr, Theresa Holtmann, Bertram Wiedenmann, Frank Tacke, Christoph Roderburg, Alexander Wree

“…Subsequently, in vitro transfections using the well-established human pancreatic NEN cell line (BON), and co-culture experiments with primary macrophages and neutrophils were performed. …”
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Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway by Qiuer Liang, Minghao Chen, Guangtian Chen, Pengli Xu, Lai Kwan Lam, Pengcheng Xie, Ting Xie, Wanqing Tu, Tianhao Liu, Xiaopeng Peng, Haoyao Yuan, Liguo Chen, Ya Xiao

“…Using an 8 % high-salt diet model, we evaluated the effects of Kae (200 mg/kg/day) in wild-type (WT) and activating transcription factor 4 (ATF4+/−) knockout mice. Additionally, human aortic endothelial cells (HAECs) cultured under high-salt conditions were used to assess Kae's protective effects, with ATF4 and acyl-CoA synthetase long-chain family member 4 (ACSL4) knocked down via siRNA transfection. …”
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Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways by Randa Ismail, Heba A. Habib, Aliaa F. Anter, Amr Amin, Gehan H. Heeba

“…Moreover, it increased MTX cytotoxicity in different human cell lines.…”
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Comparative Evaluation of Accuracy of Different Apex Locators: Propex IQ, Raypex 6, Root ZX, and Apex ID with CBCT and Periapical Radiograph—In Vitro Study by Okba Mahmoud, Mawada Hassan Awad Abdelmagied, Ahmad Hisham Dandashi, Bakr Nssaief Jasim, Hussam Alddin Tawfik Kayali, Saaid Al Shehadat

“…Thirty-five extracted single-rooted human mandibular first premolars with curvatures from 10° to 20° were selected according to the inclusion and exclusion criteria and cut at the cementoenamel junction to achieve a standard reference point for WL determination. …”
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Impact of same-day ART initiation on medical care and medication discontinuation among patients with incident HIV infection or AIDS in Taiwan: A population-based cohort study by Chen-Han Chueh, Hsiao-Jou Yu, Yu-Wen Wen, Ming-Neng Shiu, Yi-Ying Chen, Shao-Chin Chiang, Yi-Wen Tsai

“…Background: Care retention and medication adherence are crucial for individuals living with human immunodeficiency virus (HIV). Discrepancies exist between real-world evidence and randomized trials regarding early antiretroviral therapy (ART) initiation and care retention. …”
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The effect of interferon alpha administration on cytokine levels in sheep by Devran Coşkun, Merve İder, Mustafa Sedat Arslan, Rahmi Canbar, Enver Yazar

“…<b>Aim: </b>The primary aim of this study was to determine the effect of parenteral recombinant human interferon (rHuIFN)-?2a administration on serum tumor necrosis factor (TNF)-?…”
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Methods to Compare Predicted and Observed Phosphene Experience in tACS Subjects by Aprinda Indahlastari, Aditya K. Kasinadhuni, Christopher Saar, Kevin Castellano, Bakir Mousa, Munish Chauhan, Thomas H. Mareci, Rosalind J. Sadleir

“…Interpretations from phosphene analysis can serve as a first step in understanding underlying mechanisms of tACS in healthy human subjects and assist validation of computational models. …”
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Variability and Source Characterization of Regional PM of Two Urban Areas Dominated by Biomass Burning and Anthropogenic Emission by Christian Mark G. Salvador, Jhon Robin dR. Yee, Iara Chantrelle V. Coronel, Angel T. Bautista, Raymond J. Sugcang, Mark Anthony M. Lavapiez, Rey Y. Capangpangan, Preciosa Corazon B. Pabroa

“…Abstract Identifying the sources and formation pathways of particulate matter (PM) and its components is important to determine the impact of atmospheric aerosols on human health and the warming of the global atmosphere. …”
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The importance of genotyping within the climate-smart plant breeding value chain – integrative tools for genetic enhancement programs by Ana Luísa Garcia-Oliveira, Rodomiro Ortiz, Fatma Sarsu, Søren K. Rasmussen, Paterne Agre, Asrat Asfaw, Moctar Kante, Subhash Chander

“…Leveraging these technologies can facilitate the development of climate-smart cultivars that adapt effectively to climate variation, meet consumer preferences, and address human and livestock nutritional needs. Most economically important traits in crops are controlled by multiple loci often with recessive alleles. …”
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Exploring the role of ELOVLs family in lung adenocarcinoma based on bioinformatic analysis and experimental validation by Zihan Wang, Wenjing Cui, Long Liang, Jingge Qu, Yuqiang Pei, Danyang Li, Ying Luo, Yue Zhang, Yifan Qiu, Yongchang Sun

“…Methods Gene expression profiling interactive analysis (GEPIA), human protein atlas (HPA), cBioPortal, Kaplan–Meier (KM) plotter, single-sample Gene Set Enrichment Analysis (ssGSEA) algorithm and SubMap algorithms were utilized to analyze the role of ELOVLs in the LUAD. …”
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Data-driven machine learning approaches for simultaneous prediction of peak particle velocity and frequency induced by rock blasting in mining by Yewuhalashet Fissha, Prashanth Ragam, Hajime Ikeda, N. Kushal Kumar, Tsuyoshi Adachi, P.S. Paul, Youhei Kawamura

“…Both the local ecology and human communities suffer from the consequences of these vibrations. …”
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Lighting quality evaluation on growth performance and feather pecking behavior of broilers by Chenghao Pan, Rong Xiang, Jinming Pan

“…Considering the friendliness of white light to human eye, warm white light should be recommended to reduce pecking behavior in production.…”
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Fracture Strength and Marginal Adaptation of Conservative and Extended MOD Cavities Restored with Cention N by Maryam Firouzmandi, Ali Asghar Alavi, Dana Jafarpour, Soroush Sadatsharifee

“…In this experimental study, 120 human maxillary premolars were randomly divided into six groups according to the type of restoration and cavity volume (n = 20): (I) conservative MOD restored with Cention N, (II) conservative MOD restored with bonded Cention N, (III) conservative MOD restored with Z250 resin composite, (IV) extended MOD restored with Cention N, (V) extended MOD restored with bonded Cention N, and (VI) extended MOD restored with Z250 resin composite. …”
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Taxonomic refinement of Bacillus thuringiensis by Nagham Shiekh Suliman, Reza Talaei-Hassanloui, Hamid Abachi, Sadegh Zarei, Ebrahim Osdaghi

“…The bacterium taxonomically belongs to the Bacillus cereus group, which also contains human pathogenic species, e.g., Bacillus anthracis. …”
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Ganciclovir Resistance-Linked Mutations in the HCMV <i>UL97</i> Gene: Sanger Sequencing Analysis in Samples from Transplant Recipients at a Tertiary Hospital in Southern Brazil by Anna Caroline Avila da Rocha, Grazielle Motta Rodrigues, Alessandra Helena da Silva Hellwig, Dariane Castro Pereira, Fabiana Caroline Zempulski Volpato, Afonso Luís Barth, Fernanda de-Paris

“…<b>Background/Objectives:</b> Human cytomegalovirus (HCMV) DNAemia remains a significant concern for transplant recipients, largely due to mutations in the viral genome that may lead to antiviral-resistant strains. …”
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Exploring avocado consumption and health: a scoping review and evidence map by Stephen A. Fleming, Tristen L. Paul, Rachel A. F. Fleming, Alison K. Ventura, Megan A. McCrory, Corrie M. Whisner, Paul A. Spagnuolo, Louise Dye, Jana Kraft, Jana Kraft, Nikki A. Ford

“…ObjectiveThis scoping review evaluates the breadth of research on avocado intake and health, considering all populations and health outcomes (registered on Open Science Foundation at https://osf.io/nq5hk).DesignAny human intervention or observational study where effects could be isolated to consumption of avocado were included. …”
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Silencing FOXA1 suppresses inflammation caused by LPS and promotes osteogenic differentiation of periodontal ligament stem cells through the TLR4/MyD88/NF-κB pathway by Miao He, Yangdong Lin

“…Human periodontal ligament stem cells (hPDLSCs) play a critical role in the regeneration of periodontal tissue. …”
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Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study) by Lotte Haverman, Eelco Franz, Ka Yin Leung, Albert Jan Van Hoek, Hans Knoop, Cees C van den Wijngaard, Elizabeth N Mutubuki, Tessa van der Maaden, Albert Wong, Anna D Tulen, Siméon de Bruijn

“…Secondary outcomes include effect of vaccination prior to infection on persistent symptoms, loss of health-related quality of life (HRQoL) and risk factors for persisting symptoms following infection with SARS-CoV-2.Ethics and dissemination The Utrecht Medical Ethics Committee (METC) declared in February 2021 that the Medical Research Involving Human Subjects Act (WMO) does not apply to this study (METC protocol number 21-124/C). …”
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Induction of SUSD2 by STAT3 Activation Is Associated with Tumor Recurrence in HER2-Positive Breast Cancer by Yisun Jeong, Hyungjoo Kim, Daeun You, Soo Youn Cho, Sun Young Yoon, Seok Won Kim, Seok Jin Nam, Jeong Eon Lee, Sangmin Kim

“…We also found that SUSD2 expression was positively correlated with HER2 expression in a publicly available human primary breast cancer dataset. Although SUSD2 expression was associated with HER2, its expression levels were not affected by TRZ. …”
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Exploring freshwater soundscapes of tropical marshland habitats in Southeast Asia: insights into auditory sensory adaptation of wild Siamese fighting fish Betta splendens by Andreia Ramos, David Gonçalves, Raquel O. Vasconcelos

“…This is particularly relevant for freshwater ecosystems, which are extremely diverse and face escalating pressures from human activities and associated noise pollution. …”
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