A Toxicological Evaluation of Methylliberine (Dynamine®) by Timothy S. Murbach, Róbert Glávits, John R. Endres, Amy E. Clewell, Gábor Hirka, Adél Vértesi, Erzsébet Béres, Ilona Pasics Szakonyiné

“…Future studies are encouraged to corroborate the safety, and assess efficacy, of methylliberine in humans.…”
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Influence of Er,Cr:YSGG Laser Irradiation on the Push-Out Bond Strength of Zirconia and Glass Fiber Posts with Radicular Dentin by Raneem S. Alofi, Ibraheem F. Alshiddi, Yasser F. AlFawaz, Abdulaziz Alsahhaf, Khulud Abdulrahman Al-Aali, Tariq Abduljabbar, Fahim Vohra

“…Ninety extracted single-rooted human teeth were randomized into 6 groups (n = 15/group) on the basis of different posts (zirconia/glass fiber) and Er,Cr:YSGG laser tips (axial and radial). …”
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Spawning biology, breeding, and larval rearing techniques for Xenentodon cancila (Hamilton) for aquaculture and recreational use in Bangladesh: The first approach by Paul Shyamal Kumar, Sarker Bhakta Supratim, Sultana Nahid, Pall Jewel Chandra, Perven Tania, Saha Debasish, Majumdar Priyanka Rani

“…Nine doses of common carp pituitary gland (CPG), human chorionic gonadotropin (HCG), and Ovaprim for breeding were administered, except in the control treatment that was without hormones. …”
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Exosomes derived from hUC-MSCs exhibit ameliorative efficacy upon previous cesarean scar defect via orchestrating β-TrCP/CHK1 axis by Xiaoling Zeng, Yuan Liao, Dan Huang, Jing Yang, Zhihua Dai, Zhengyong Chen, Xin Luo, Han Gong, Shengwen Huang, Leisheng Zhang

“…On the one hand, we took advantage of the TGF-β-induced in vitro myofibrotic model and the full-thickness uterine injury rat model to verify the efficacy of human umbilical cord MSC-derived exosomes (hUC-MSC-Exos). …”
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Trends in blood transfusion and causes of blood wastage: a retrospective analysis in a teaching hospital by Ju-huei Chien, Chao-yuan Yao, Hui-fen Chen, Tsing-Fen Ho

“…Conclusions The study highlights that blood wastage often stems from human error or improper storage conditions. The leading cause of platelet product disposal is incorrect storage temperatures, along with the inability to repurpose thawed plasma for plasma products. …”
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Longitudinal Metabolomics Data Analysis Informed by Mechanistic Models by Lu Li, Huub Hoefsloot, Barbara M. Bakker, David Horner, Morten A. Rasmussen, Age K. Smilde, Evrim Acar

“…Simulated challenge test data generated using a human whole-body metabolic model were also arranged as a third-order tensor: <i>virtual subjects</i> by <i>metabolites</i> by <i>time samples</i>. …”
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Superior biomechanical stability of pedicle screws compared to lateral mass screws: recommendations for bicortical positioning and enhancing bone contact in geriatric C1 vertebrae by Leon-Gordian Leonhardt, Leonie Rörup, Anna Lena Kammal, Michael Hahn, Marc Dreimann, Benjamin Ondruschka, Felix Nikolai von Brackel, Tim Rolvien, Lennart Viezens, Simon von Kroge

“…Purpose The aim of this study was a comparative analysis of the mechanical durability of screw fixation concerning microstructural characteristics of the trajectories of LMS and PS in mono- and bicortical position. Methods Human C1 from geriatric body donors (n = 28; 50% female, age 80.8 ± 13.9 years) were collected and characterized based on their bone microstructure. …”
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Visual impairment prevention by early detection of diabetic retinopathy based on stacked auto-encoder by Shagufta Almas, Fazli Wahid, Sikandar Ali, Ahmed Alkhyyat, Kamran Ullah, Jawad Khan, Youngmoon Lee

“…Traditional diagnosis methods are prone to human error, necessitating accurate alternatives. …”
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Efficient and accurate tobacco leaf maturity detection: an improved YOLOv10 model with DCNv3 and efficient local attention integration by Yi Shi, Hong Wang, Fei Wang, Yingkuan Wang, Jianjun Liu, Long Zhao, Hui Wang, Feng Zhang, Qiongmin Cheng, Shunhao Qing

“…This research addresses the inherent subjectivity and variability in conventional maturity evaluation techniques reliant on human expertise by introducing an innovative YOLOv10-based method for tobacco leaf maturity detection. …”
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A new and automated risk prediction of coronary artery disease using clinical endpoints and medical imaging-derived patient-specific insights: protocol for the retrospective GeoCAD... by Louisa Jorm, Daniel Moses, Dona Adikari, Ramtin Gharleghi, Shisheng Zhang, Arcot Sowmya, Sze-Yuan Ooi, Susann Beier

“…The objectives are to (1) profile CTCA images with respect to variations in anatomical shape and associated haemodynamic risk expressing, at least in part, an individual’s CAD risk, (2) develop a machine-learning algorithm for the rapid assessment of anatomical risk directly from unprocessed CTCA images and (3) to build a novel CAD risk model combining traditional risk factors with these novel anatomical biomarkers to provide a higher accuracy CAD risk prediction tool.Ethics and dissemination The study protocol has been approved by the St Vincent’s Hospital Human Research Ethics Committee, Sydney—2020/ETH02127 and the NSW Population and Health Service Research Ethics Committee—2021/ETH00990. …”
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Hydrogeochemistry of Surface and Ground Water in Alatening Village, Northwest Region, Cameroon by Kahnji Iren Njoyim, Lucas Kengni, Margaret Awah Tita, Estella Njoyim Buleng Tamungang, Vitalis Fonfo Fonzenyuy, Bertrand Tatoh Aziwo

“…Electrical conductivity and total dissolved solids (TDS) were low implying low mineralised water which can also lead to shortage of important minerals in humans. All the essential ions were found within the WHO guideline values without any significant change in concentrations between seasons (p>0.05). …”
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Harnessing new mHealth technologies to Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART trial): a protocol for a randomised controlled trial by Ben J Marais, Joel Negin, James Johnston, Virginia Wiseman, Greg J Fox, Thu Anh Nguyen, Binh Hoa Nguyen, Viet Nhung Nguyen, Justin Beardsley, Guy Barrington Marks, Kavindhran Velen, Tho Dang, Hoang Anh Nguyen, Dinh Hoa Vu, Thu Thuong Do, Cuong Pham Duc, Huu Lan Nguyen, Huu Thuong Pham, Warwick Britton

“…Cost-effectiveness will be presented as an incremental cost per patient successfully treated and an incremental cost per quality-adjusted life-year gained.Ethics Ethical approval for the study was granted by The University of Sydney Human Research Ethics Committee (2019/676).Dissemination Study findings will be disseminated to participants and published in peer-reviewed journals and conference proceedings.Trial registration number ACTRN12620000681954.…”
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Spatiotemporal simulation of blue-green space pattern evolution and carbon storage under different SSP-RCP scenarios in Wuhan by Guiyuan Li, Wangzhen Wang, Bowen Li, Zhongyuan Duan, Liang Hu, Jingwen Liu

“…Abstract Rapid socioeconomic growth has altered land use patterns, resulting in a surge in worldwide CO2 emissions, triggering global climate challenges and adversely affecting human health, safety, and sustainable socioeconomic development. …”
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Dexmedetomidine Attenuates Monocyte-Endothelial Adherence via Inhibiting Connexin43 on Vascular Endothelial Cells by Yunfei Chai, Runying Yu, Yong Liu, Sheng Wang, Dongdong Yuan, Jimei Chen

“…For the first time, we clarify effects of dexmedetomidine on monocyte-endothelial adherence and whether its underlying mechanism is relative to connexin43 (Cx43), a key factor regulating monocyte-endothelial adherence. U937 monocytes and human umbilical vein endothelial cells (HUVECs) were used to explore monocyte-endothelial adherence. …”
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Survival outcomes of marijuana users in p16 positive oropharynx cancer patients by Han Zhang, Michael Xie, Marc Levin, Stuart D. Archibald, B. Stanley Jackson, J. E. M. Young, Michael K. Gupta

“…Abstract Background Oropharynx squamous cell carcinoma (OPSCC) has become the predominant subsite for head and neck mucosal cancers (HNC) due to the rise of human papillomavirus (HPV) related disease. Previous studies have suggested an association between marijuana use and HPV-related OPSCC. …”
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Phylogeography and biological characterization of H12N2 virus isolated from whooper swan in Central China by Pengfei Ren, Zhen Gao, Xing Li, Jiao Tang, Pei Li, Zhonglin Huang, Jinchi Guo, Pengfei Cui, Lin Jin, Junping Li, Libin Liang

“…When AIVs originating from wild birds cross species barriers to infect mammals or humans, they pose a significant threat to public health. …”
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Conservation networks do not match the ecological requirements of amphibians by Matutini, Florence, Baudry, Jacques, Fortin, Marie-Josee, Pain, Guillaume, Pithon, Josephine

“…Here, we compared the ecological requirements of amphibian species with existing conservation network coverage in a human-dominated region of western France. First, we mapped suitable habitat distributions for nine species of amphibian with varying ecological requirements and mobility. …”
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Genomic insights into the specialisation and selection of the Jinding duck by H. Chen, Y. Huang, J. Xue, K. luo, H. Tang, S. Zheng, Y. Xiong, Y. Wu, J. Li, R. Xuan, R. Xiong, Y. Gong, X. Fang, L. Wang, J. Miao, J. Zhou, H. Tan, Y. Wang, L. Wu, J. Ouyang, Y. Shen, X. Yan

“…The domestication of ducks represents a pivotal evolutionary shift from the unguided propagation of wild species to deliberate human-mediated selection, culminating in distinct behavioural, morphological, and physiological traits that differentiate domesticated ducks from their wild counterparts. …”
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BPZ inhibits early mouse embryonic development by disrupting maternal-to-zygotic transition and mitochondrial function by Zhiming Ding, Huilei Chen, Huiru Cheng, Caiyun Wu, Hongzhen Ruan, Bingjing Zhu, Ping Zhou, Zuying Xu, Huifen Xiang

“…Bisphenol Z (BPZ) is used as an alternative to BPA, and humans are widely exposed to BPZ through various routes. …”
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Comparing low-cost activated carbon made from coffee waste and bagasse to remove heavy metals and methylene blue dye by Nahla. M. Salatein, Mahmoud Shaaban, Irene. S. Fahim

“…Heavy metal contamination from wastewater, mainly iron (Fe), copper (Cu), and methylene blue (MB) dye, presents a substantial risk to both human health and the environment. Biomass-sourced activated carbon, with its porous structure and environmentally friendly adsorption properties, offers a sustainable method for removing these metals. …”
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