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30821
Metformin Use and Survival in Patients with Advanced Extrahepatic Cholangiocarcinoma: A Single-Center Cohort Study in Fuyang, China
Published 2021-01-01“…In recent years, anticancer properties of metformin have been revealed for numerous human malignancies. However, there are few indications available regarding the feasibility and safety of these studies in an advanced extrahepatic cholangiocarcinoma (EHCC) population. …”
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30822
Universal Health Coverage in Bangladesh: Activities, Challenges, and Suggestions
Published 2019-01-01“…While others pertain to the health sector’s implementation shortfalls including issues of human resources, political interference, monitoring, and supervision, most key informants discussed demand-side barriers too, such as sociocultural disinclination, historical mistrust, and lack of empowerment. …”
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30823
Microleakage Evaluation of Two Methacrylate-Based Composites (GC Kalore and Luna SDI) in Class II Restorations: A Laboratory Study
Published 2022-01-01“…In this experimental study, a total of 18 intact human premolars previously extracted for periodontal and orthodontic reasons were randomly divided into two groups. …”
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30824
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30825
Do you have enough space? Habitat selection of insectivorous cave-dwelling bats in fragmented landscapes of Eastern Amazon.
Published 2025-01-01“…We used radio telemetry to assess their use of habitats, under the prediction that these species prefer preserved habitats for their foraging bouts, avoiding human-modified habitats. We also anticipated larger areas and commuting distances for both species when foraging in disturbed landscapes. …”
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30826
Osteoprotegerin as an Emerging Biomarker of Carotid Artery Stenosis? A Scoping Review with Meta-Analysis
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30827
Strategic foresight of staffing needs of innovative development of socio-economic systems
Published 2019-03-01“…The research has been conducted in order to develop theoretical and methodological approaches to forecasting the future needs of the innovative economy in personnel to ensure the demand for formed human resources capacity. Development of basic techniques and instruments of calculation of need of innovative economy for highly qualified personnel on long-term and medium-term prospects has been based on such methodological approaches as system, activity and competence-based approaches, situational approach, methodology of the interactive, understanding and interpretive sociology, methodology of synergy, network thinking and social management, methodology of the modal analysis. …”
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30828
The impact of vaccine access difficulties on HPV vaccine intention and uptake among female university students in China
Published 2025-01-01“…Abstract Background Ensuring vaccine access is a prerequisite for promoting human papilloma virus (HPV) vaccination. Although HPV vaccination efforts in China have primarily focused on young females, little research has examined the difficulties they face in accessing the HPV vaccine and its impact on vaccine uptake and intention. …”
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30830
مطالعات اقتصاد مقاومتی: غلبۀ متنپژوهی بر نظریه و واقعیت!
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30831
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30832
Identification of cuproptosis and ferroptosis-related subtypes and development of a prognostic signature in colon cancer.
Published 2025-01-01“…Colon cancer, as a highly prevalent malignant tumor globally, poses a significant threat to human health. In recent years, ferroptosis and cuproptosis, as two novel forms of cell death, have attracted widespread attention for their potential roles in the development and treatment of colon cancer. …”
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30833
Five Years Follow-Up of Acrysof Cachet® Angle-Supported Phakic Intraocular Lens Implantation for Myopia Correction
Published 2022-01-01“…., Fort Worth, TX) is designed to correct high refractive errors in human eyes. The aim of this study was to evaluate the outcome of AcrySof Cachet® angle-supported pIOL implantation with particular regard to efficacy and safety of the implant over a 60-month follow-up period. …”
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30834
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30836
Therapeutic potential of phytocompounds of Bacopa monnieri (L.) Wettst (literature review)
Published 2024-10-01“…The extract was not toxic to humans. Numerous clinical trials show the effectiveness of the use of extracts in the treatment of anhedonia, depression, Alzheimer's disease, Parkinson's disease, dementia and hyperactivity. …”
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30837
Virtual Screening, Toxicity Evaluation and Pharmacokinetics of Erythrina Alkaloids as Acetylcholinesterase Inhibitor Candidates from Natural Products
Published 2025-02-01“…The objective of this study is to identify Erythrina alkaloids with strong inhibitory capacity against AChE and favorable pharmacokinetic profiles.Materials and Methods: A multi-step computational approach was employed, beginning with the virtual screening of 143 Erythrina alkaloid structures using molecular docking against the human AChE crystal structure. The binding affinities were compared with the known AChE inhibitor, galantamine. …”
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30838
Like milk on the stove: Healthcare professionals navigating uncertainty when caring for families with 22q11DS.
Published 2025-01-01“…<h4>Introduction</h4>22q11 deletion syndrome (22q11DS) results from a microdeletion on chromosome 22 and is the most common microdeletion disorder in humans, affecting 1 in 2148 live births. Clinical manifestations vary widely among individuals and across different life stages. …”
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30839
Innovations and barriers in sustainable and green finance for advancing sustainable development goals
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30840
Repurposing antiviral drugs targeting the PARP-1 and HER2 pathways with multifaceted impacts through integrated network analysis and molecular mechanics
Published 2025-06-01“…Through the application of network pharmacology, gene ontology, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, this study identified Human Epidermal Growth Factor Receptor 2 (HER2) and Poly [ADP ribose] polymerase 1(PARP-1) as key targets involved in the molecular pathways associated with breast cancer. …”
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