A lectin produced by a Streptomyces species targets mammalian pancreatic acinar cells in mice and humans by Janine C. Quijano, Honoka Natsuyama, Alonso Tapia, Karine Bagramyan, Jose A. Ortiz, Jacob Mares, Markus Kalkum, Yoko Fujita-Yamaguchi, Hsun Teresa Ku

“…Previously, a bacterial lectin, named Streptomyces hemagglutinin (SHA), was found to agglutinate human type B erythrocytes. However, the binding of SHA to mammalian cell types other than human erythrocytes has not been explored. …”
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Social Work and Human Rights: Uncrossed Paths Between Exposure, Engagement, Lens, and Methods in Professional Practice by Maria Irene Carvalho, Cristina Albuquerque, Pedro Borrego

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Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression by Pedro J Romero, Mauro Delorenzi, Amaia Martínez-Usatorre, Laura Ciarloni, Noushin Hadadi, Eric Durandau, Sylvain Monnier-Benoit, Paolo Angelino, Victoria Wosika, Alessandra Jordano Conforte, Sara S Fonseca Costa, Hector Fabio Satizabal, Jérémie Despraz, Andres Perez-Uribe, Stephan Morgenthaler, Brian Hashemi, Sahar Hosseinian-Ehrensberger

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Longitudinal Screening for Diabetic Retinopathy in a Nationwide Screening Program: Comparing Deep Learning and Human Graders by Jirawut Limwattanayingyong, Variya Nganthavee, Kasem Seresirikachorn, Tassapol Singalavanija, Ngamphol Soonthornworasiri, Varis Ruamviboonsuk, Chetan Rao, Rajiv Raman, Andrzej Grzybowski, Mike Schaekermann, Lily H. Peng, Dale R. Webster, Christopher Semturs, Jonathan Krause, Rory Sayres, Fred Hersch, Richa Tiwari, Yun Liu, Paisan Ruamviboonsuk

“…To evaluate diabetic retinopathy (DR) screening via deep learning (DL) and trained human graders (HG) in a longitudinal cohort, as case spectrum shifts based on treatment referral and new-onset DR. …”
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Correction: Human-machine interactions with clinical phrase prediction system, aligning with Zipf's least effort principle? by PLOS One Staff

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Physical Activity Protects the Human Brain against Metabolic Stress Induced by a Postprandial and Chronic Inflammation by Leo Pruimboom, Charles L. Raison, Frits A. J. Muskiet

“…Although the notion that increased physical activity would improve health in the modern world is widespread, here we provide a novel perspective on this truism by providing evidence that recovery of normal human behaviour, such as spontaneous physical activity, would calm proinflammatory activity, thereby allocating more energy to the brain and other organs, and by doing so would improve human health.…”
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Simulation of Software Development Team Productivity Incorporating Social and Human Factors: A System Dynamics Model by Luz Marcela Restrepo-Tamayo, Gloria Piedad Gasca-Hurtado, Johnny Valencia-Calvo

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Human Adipose-Derived Mesenchymal Stem Cells Cryopreservation and Thawing Decrease α4-Integrin Expression by Ana Carolina Irioda, Rafael Cassilha, Larissa Zocche, Julio Cesar Francisco, Ricardo Correa Cunha, Priscila Elias Ferreira, Luiz Cesar Guarita-Souza, Reginaldo Justino Ferreira, Bassam Felipe Mogharbel, Venkata Naga Srikanth Garikipati, Daiany Souza, Mirian Perlingeiro Beltrame, Katherine Athayde Teixeira de Carvalho

“…The aim of this study was to analyze human adipose tissue-derived mesenchymal stem cells phenotypic expression (CD34, CD45, CD73, CD90, CD105, and CD49d), colony forming unit ability, viability, and differentiation potential before and after cryopreservation. …”
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Designing Gold Nanoparticle-Ensembles as Surface Enhanced Raman Scattering Tags inside Human Retinal Cells by Sanda Boca, Dumitrita Rugina, Adela Pintea, Nicolae Leopold, Simion Astilean

“…No further encoding operation is necessary in our case since part of ascorbic acid used as reducing agent remains attached in the interparticle junctions, providing persistent and strong SERS signal when the fabricated tags are internalized by human retinal cells. Our studies demonstrate a promising potential of new SERS-active nanoparticles to serve as effective reporters for biomedical tracing and imaging.…”
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Cutaneous Human Papillomavirus E7 Type-Specific Effects on Differentiation and Proliferation of Organotypic Skin Cultures by K. Westphal, B. Akgül, A. Storey, I. Nindl

“…Background: A role for cutaneous human β-papillomavirus (HPV) types as co-factors in the development of non-melanoma skin cancer has been postulated. …”
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Mathematical Model of Human Papillomavirus (HPV) Dynamics With Double-Dose Vaccination and Its Impact on Cervical Cancer by Henok Desalegn Desta, Getachew Teshome Tilahun, Tariku Merga Tolasa, Mulugeta Geremew Geleso

“…We develop a deterministic mathematical model to investigate the transmission dynamics of human papillomavirus (HPV) and its impact on cervical cancer. …”
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Effects of linsitinib on M22 and IGF:1-treated 3D spheroids of human orbital fibroblasts by Fumihito Hikage, Megumi Suzuki, Tatsuya Sato, Araya Umetsu, Toshifumi Ogawa, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe

“…Abstract To elucidate the role of IGF1R inhibition in the pathogenesis of Graves’ orbitopathy (GO), the effects of linsitinib (Lins) on a recombinant human TSHR antibody (M22) and IGF1 to activate TSHR and IGF1R of human orbital fibroblasts (HOFs) obtained from patients without GO (HOFs) and patients with GO (GHOFs) were studied using in vitro three-dimensional (3D) spheroid models in addition to their 2D planar cell culture. …”
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Co-Expression of Plexin-B1 and Met in Human Breast and Ovary Tumours Enhances the Risk of Progression by Guido Valente, Giuseppina Nicotra, Marisa Arrondini, Roberta Castino, Lorena Capparuccia, Maria Prat, Simonetta Kerim, Luca Tamagnone, Ciro Isidoro

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From Skinned Cats to Angels in Fur: Feline Traces and the Start of the Cat-Human Relationship in Victorian England by Hilda Kean

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An updated systematic review with meta-analysis and meta-regression of the factors associated with human visceral leishmaniasis in the Americas by Anna Gabryela Sousa Duarte, Guilherme Loureiro Werneck, Sarah de Farias Lelis, Thays Santos Mendonça, Daniela Dias Vasconcelos, Tiago Silveira Gontijo, Álisson Oliveira dos Santos, Lucas Edel Donato, Vinícius Silva Belo

“…Abstract Background Human visceral leishmaniasis (VL) is a systemic disease with high case-fatality rates and a widespread distribution. …”
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Retraction: Nanocurcumin Prevents Hypoxia Induced Stress in Primary Human Ventricular Cardiomyocytes by Maintaining Mitochondrial Homeostasis. by PLOS One Editors

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The impact of an imperfect vaccine and pap cytologyscreening on the transmission of human papillomavirus and occurrenceof associated cervical dysplasia and cancer by Tufail Malik, Jody Reimer, Abba Gumel, Elamin H. Elbasha, Salaheddin Mahmud

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Variable Cell Transmission Model for Mixed Traffic Flow with Connected Automated Vehicles and Human-Driven Vehicles by Yuting Jin, Zhihong Yao, Jiazhe Han, Lu Hu, Yangsheng Jiang

“…The current research on the mixed traffic flow characteristics of human-driven vehicles (HDVs) and connected automated vehicles (CAVs) mainly focuses on the micro-level. …”
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Development of Entrepreneurial Activity Using the Integration of Human Capital and Green Technologies to Optimize the Sustainable Development of the Territories by Alma Karshalova, Aidos Akpanov, Santay Tleubayeva, Anuar Belgibayev, Askar Makhmudov, Aigul Atchabarova, Margarita Zholayeva

“…The purpose of the study is to identify ways to develop entrepreneurial activity by integrating human capital and green technologies to optimize the sustainable development of the tourism sector. …”
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MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma by Peng Xu, Fei-Hang Ge, Wen-Xin Li, Zhen Xu, Xue-Li Wang, Jing-Lan Shen, Ai-Bo Xu, Rong-Rong Hao

“…In addition, miR-147a expression was elevated in human glioblastoma cells upon erastin or RSL3 stimulation. …”
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