Health effects of mixed metal exposure on accelerating aging among the elderly population by Chuanli Yang, Jijun Zhang, Haohan Liu, Qin Hong, Yunhe Fan, Jie An, Haijia Zhang, Xiaobing Shen, Xiushan Dong

“…Background: Human exposure to heavy metals occurs through multiple pathways in daily life. …”
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Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics by Isy Petit, Quentin Faucher, Jean-Sébastien Bernard, Perrine Giunchi, Antoine Humeau, François-Ludovic Sauvage, Pierre Marquet, Nicolas Védrenne, Florent Di Meo

“…Predictivity can be improved by using Organs-on-Chips, which are more physiological, human-oriented, micro-engineered devices that include microfluidics. …”
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Spatiotemporal Variability of Hot Days in Association with the Large-Scale Atmospheric Drivers over Vietnam by Chinh Ta Huu, Tan Phan Van, Khiem Mai Van, Thang Vu Van, Lam Hoang Phuc, Worapong Lohpaisankrit, Quoc Bao Pham, Trinh Trong Nguyen, Phong Nguyen Thanh

“…The hot days and extreme summer events make the weather harsh and significantly affect human health and the environment. This study presents the spatiotemporal distribution of the number of hot days (NHDs) in Vietnam. …”
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Oridonin ameliorates renal fibrosis in diabetic nephropathy by inhibiting the Wnt/β-catenin signaling pathway by Jushuang Li, Lan Shu, Qianqian Jiang, Baohong Feng, Zhimin Bi, Geli Zhu, Yanxia Zhang, Xiangyou Li, Jun Wu

“…Here, we investigated the mechanism through which Ori affects the Wnt/β-catenin signaling pathway in diabetic rats and human proximal tubular epithelial cells (HK-2) exposed to high glucose (HG) levels. …”
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Microbial bioindicators associated with cadmium uptake in sixteen genotypes of Theobroma cacao by Jennifer E. Schmidt, Caleb A. Lewis, Alana J. Firl, Pathmanathan Umaharan

“…Recent regulatory limits on concentrations of cadmium (Cd), an element of concern for human health, have made Cd reduction a key issue in the global chocolate industry. …”
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Long-Term Clinical Outcomes of Small-Incision Femtosecond Laser-Assisted Intracorneal Concave Lenticule Implantation in Patients with Keratoconus by Qi Wei, Hui Ding, Ke Nie, He Jin, Tan Zhong, Hanyang Yu, Zhenduo Yang, Shisi Hu, Linyi He, Xingwu Zhong

“…The purpose of this study was to evaluate the long-term prognosis of small-incision femtosecond laser-assisted intracorneal concave lenticule implantation (SFII) in correction of human keratoconus. Methods. This was a prospective study for 11 patients who received SFII after being diagnosed as progressive keratoconus based on the Amsler–Krumeich classification system. …”
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PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism? by Justine Henriot, André Dallmann, François Dupuis, Jérémy Perrier, Sebastian Frechen

“…To this end, a systematic review of the absolute CYP3A expression in the human gastrointestinal tract and liver was conducted. …”
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An explorative qualitative study of barriers to the use of health and mental health services among migrant female sex workers in Germany and needs for action by Anastasiia Lotysh, Hürrem Tezcan-Güntekin, Olivia Kalinowski, Gizem Kaya, Franziska Kroehn-Liedtke, Hristiana Mihaylova, Meryam Schouler-Ocak, Wulf Rössler

“…Moreover, needs for actions were identified, which can be used for deriving recommendations for the improvement of healthcare situation of migrant sex workers living in Berlin.Conclusion/discussionHealth services and future intervention studies should consider barriers identified in this study to improve the health services utilization and health of sex workers as part of the effort to protect the right of humans to health.…”
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Neuromuscular electrical stimulation training induces myonuclear accretion and hypertrophy in mice without overt signs of muscle damage and regeneration by Aurélie Fessard, Aliki Zavoriti, Natacha Boyer, Jules Guillemaud, Masoud Rahmati, Peggy Del Carmine, Christelle Gobet, Bénédicte Chazaud, Julien Gondin

“…This method is commonly referred to as NeuroMuscular Electrical Simulation (NMES) in Human. Each NMES training session consisted of 80 isometric contractions delivered at ∼15% of maximal tetanic force to avoid muscle damage. …”
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An Efficient and Hybrid Deep Learning-Driven Model to Enhance Security and Performance of Healthcare Internet of Things by Muhammad Babar, Muhammad Usman Tariq, Basit Qureshi, Zabeeh Ullah, Fahim Arif, Zahid Khan

“…Sensors and actuators are used in smart medical devices to collect data about the human body, which is then sent to the fog layer for analysis. …”
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Effect of Green Roofs on the Thermal Environment of Prototype Broiler Houses by Maria Angela de Souza, Fernanda Campos de Sousa, Alex Lopes da Silva, Thauane Cordeiro Soares, Charles Paranhos Oliveira, Ricardo Brauer Vigoderis, Fernando da Costa Baêta, Ilda de Fátima Ferreira Tinôco

“…Parameters measured included air temperature, relative humidity, internal roof surface temperature, Temperature and Humidity Index (THI), Black Globe Humidity Index (BGHI), Human Comfort Index (HCI), and Thermal Radiation Load (TRL) under both open and closed conditions. …”
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Heart Rate Variability: A Psychophysiological Factor Related to Both Regular Physical Activity and Eudaimonic Well‐Being Among Young Adults by Yoshino Murakami, Daisuke Goto, Hayato Tsukamoto, Kazuho Yamaura, Takeshi Hashimoto

“…ABSTRACT Introduction Eudaimonic well‐being (EWB), which refers to optimal human functioning, is associated with psychophysiological outcomes, such as reduced inflammation and a lower risk of depression. …”
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Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p by Lei Xu, Gang Zhao, Hong Zhu, Shijun Wang, Aijun Sun, Yunzeng Zou, Junbo Ge

“…Induction with Rosiglitazone activated PPAR-γ and promoted its nuclear translocation in cultured human umbilical vein endothelial cells (HUVECs). …”
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Identification of retinol dehydrogenase 10 as a shared biomarker for metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus by Fangyu Li, Rui Li, Hongjun Deng

“…Similarly, serum levels of RDH10 were significantly lower in MASLD and T2DM model mice and humans than in controls.ConclusionOur study suggests that RDH10 is a common diagnostic marker for MASLD and T2DM and provides new research directions for the prevention and treatment of MASLD and T2DM.…”
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Fuzzy modeling using the similarity-based approximate reasoning system by Jalal Chachi, Mehdi Jalalvand

“…Just as we humans use many different types of inferential procedures to help us understand things or to make decisions,  there are many different fuzzy logic inferential procedures, including similarity-based approaches. …”
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Exploring household water conservation behaviors in Saudi Arabia: A structural equation modeling approach by Abdulaziz I. Almulhim, Ismaila Rimi Abubakar

“…Water conservation is crucial for human sustainable development, particularly in the face of increasing global challenges such as freshwater scarcity, rapid urbanization, and climate change. …”
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Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers by Ammelie Svea Boje, Lukas Pekar, Katharina Koep, Britta Lipinski, Brian Rabinovich, Andreas Evers, Carina Lynn Gehlert, Steffen Krohn, Yanping Xiao, Simon Krah, Rinat Zaynagetdinov, Lars Toleikis, Sven Poetzsch, Matthias Peipp, Stefan Zielonka, Katja Klausz

“…For EGFR-positive tumor targeting, humanized antigen-binding domains of therapeutic antibody cetuximab were used. …”
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Race to the Moon or the Bottom? Applications, Performance, and Ethical Considerations of Artificial Intelligence in Prosthodontics and Implant Dentistry by Amal Alfaraj, Toshiki Nagai, Hawra AlQallaf, Wei-Shao Lin

“…Regarding ethical issues, five studies identified concerns such as data privacy, system bias, and the potential replacement of human roles by AI. While patients generally viewed AI positively, dental professionals expressed hesitancy due to a lack of familiarity and regulatory guidelines, highlighting the need for better education and ethical frameworks. …”
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Application of Blockchain Technology in Carbon Trading Market: A Systematic Review by Timileyin P. Abiodun, Nnamdi I. Nwulu, Peter O. Olukanmi

“…The carbon trading system is a mechanism that employs carbon caps (limits) and taxation to regulate the rate of carbon dioxide emissions produced by human activities. To further strengthen the effectiveness of this mechanism, the United Nations (UN) initiated the Kyoto Protocol in 1997, enabling the trading of carbon emission rights in exchange for financial compensation. …”
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Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging by Hugo Helbert, Winnie Deuther-Conrad, Michel de Haan, Barbara Wenzel, Gert Luurtsema, Wiktor Szymanski, Peter Brust, Rudi A. J. O. Dierckx, Ben L. Feringa, Philip H. Elsinga

“…New in vitro binding data is also made available for (-)-FEOBV with human-sourced σ1 receptors, revealing a 300-fold stronger affinity for VAChT compared to σ receptors. …”
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