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30281
Bridging brain and blood: a prospective view on neuroimaging-exosome correlations in HIV-associated neurocognitive disorders
Published 2025-01-01“…HIV-associated neurocognitive disorder (HAND) is a complex neurological complication resulting from human immunodeficiency virus (HIV) infection, affecting about 50% of individuals with HIV and significantly diminishing their quality of life. …”
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30282
Abundance, occurrence, and degradation of airborne antibiotic resistance genes in coastal and marine atmospheres
Published 2025-01-01“…Antibiotic resistance genes (ARGs) may have significant impacts on human health and ecosystems. Airborne ARGs are reportedly widely distributed across inland cities, but little is known about their abundance in marine atmospheres. …”
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30283
Factors associated with girl child marriage in Iran: a qualitative socio-ecological approach
Published 2025-01-01“…IntroductionGirl child marriage is an example of a human rights violation, the unfortunate consequences of which have raised growing concerns in the health system and have become a development challenge. …”
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30284
An approach to predict and inhibit Amyloid Beta dimerization pattern in Alzheimer’s disease
Published 2025-06-01“…Alzheimer’s Disease (AD) is one of the leading neurodegenerative diseases that affect the human population. Several hypotheses are in the pipeline to establish the commencement of this disease; however, the amyloid hypothesis is one of the most widely accepted ones. …”
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30285
Assessing Knowledge, Attitudes, and Practices of Medication Disposal: A Study on Rural Communities in Sarojini Nagar, Lucknow
Published 2024-12-01“…Introduction: The increasing global consumption of medications has led to a significant rise in the improper disposal of unused and expired drugs, posing risks to both human health and the environment. Objective: This study aims to evaluate the understanding, beliefs, and behaviours related to the disposal of such medications within the rural community of Sarojini Nagar, Lucknow. …”
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30286
Safety Evaluation for Connected and Autonomous Vehicles’ Exclusive Lanes considering Penetrate Ratios and Impact of Trucks Using Surrogate Safety Measures
Published 2020-01-01“…However, most of the previous research studies neglected comprehensive consideration of the safety impact on different market penetration rates (MPRs) of CAVs, traffic demands, and proportion of trucks in mixture CAVs with human’s driven vehicle environment. On this basis, this study is to (1) identify the safety impact on exclusive lanes for CAVs under different MPRs with different traffic demands and (2) investigate the safety impact of trucks for CAV exclusive lanes on mixture environment. …”
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30287
circ_0075048 silencing regulates LCP1 to improve IL-1β-induced chondrocyte injury by binding with miR-663b
Published 2025-01-01“…Methods The expression of circ_0075048 was analyzed based on the Gene Expression Omnibus dataset GSE178724. Human chondrocytes were stimulated with IL-1β to establish an in vitro OA model. …”
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30288
Phenolic and amino acid profiles, and antioxidant properties of third generation snack foods adding Citrus mitis by-products and milk powder: impact of extrusion processing and mic...
Published 2025-02-01“…Total flavonoid content (TFC), hydroxyl radical scavenging activity (HRSA), and inhibition of human LDL oxidation (ILDLox) decreased in PS2 regarding PS1. …”
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30289
Rapid and Efficient Purification of Functional Collectin-12 and Its Opsonic Activity against Fungal Pathogens
Published 2019-01-01“…Furthermore, CL-12 has been shown to be associated with the pathogenesis of human diseases such as Alzheimer’s disease and multiple sclerosis lesion development. …”
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30290
Temporal variation in habitat quality shapes the distribution–abundance relationship in waterbirds at landscape scale
Published 2024-12-01“…This finding has important practical consequences, particularly in landscapes under human exploitation, where management decisions can determine ecosystem structure. …”
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30291
Overexpression of IL-6 and STAT3 may provide new insights into ovine pulmonary adenocarcinoma development
Published 2025-01-01“…Abstract Background Ovine pulmonary adenocarcinoma (OPA) is caused by Jaagsiekte sheep retrovirus (JSRV) and is considered an important potential animal model for human lung cancer. The precise mechanisms of OPA oncogenesis are still uncertain. …”
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30292
Barriers Affecting Promotion of Active Transportation: A Study on Pedestrian and Bicycle Network Connectivity in Melbourne’s West
Published 2024-12-01“…In this research, we focused on the suburb of Point Cook, located within the City of Wyndham in Melbourne’s west, owing to its rising human population and private vehicle ownership. The primary aim of this research is to examine the barriers in the interconnectivity of active transport networks for pedestrians and cyclists and to determine the segments of the transportation network that are not accessible to Point Cook residents. …”
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30293
IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSION
Published 2023-10-01“…Thus, the decrease in the level of non-protein-bound sulfhydryl groups of erythrocytes enables to assess the degree of stress that affects the human body, as well as the antioxidant protection enhancement in patients with hypertension after taking vitamin E and selenium both before and after engaging in physical exercise.…”
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30294
Antibacterial Potential of Crude Extracts from <i>Cylindrospermum alatosporum</i> NR125682 and <i>Loriellopsis cavernicola</i> NR117881
Published 2025-01-01“…The challenges of antimicrobial resistance (AMR) to human health have pushed for the discovery of a new antibiotics agent from natural products. …”
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30295
Correlation among blastocoel fluid DNA level, apoptotic genes expression and preimplantation aneuploidy
Published 2025-02-01“…This study aimed to develop less invasive methods for predicting ploidy status by investigating how ploidy status affects blastocoel fluid DNA (BF-DNA) levels and apoptotic gene expression as indicators of embryo viability. Human blastocysts were classified into three groups; survivable embryo (SE), fatal single and double aneuploidy (FSDA) and multiple aneuploidy (MA) using array comparative genomic hybridization (array-CGH) by trophectoderm biopsy. …”
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30296
Differential expression of DNA fragmentation factor 45 in leukoplakia and oral squamous cell carcinoma and its correlation with TNF-α levels
Published 2024-06-01“…Background: DNA fragmentation factor (DFF) - 45, a heterodimeric protein, involved in apoptotic processes is found to play important role in various human cancers. Its role in the development and progression of oral cavity squamous cell carcinoma (OSCC) is still unclear. …”
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30297
Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes
Published 2022-01-01“…Our data show that eCIRP expression was increased in the sera of psoriasis patients and imiquimod- (IMQ-) induced psoriatic mice and cells stimulated with proinflammatory cytokines (IL-1α, IL-17A, IL-22, oncostatin M, and TNF-α; mix M5). Recombinant human CIRP (rhCIRP) promoted the expression of the proinflammatory cytokines TNF-α, IL-6, and IL-8 and the activation of NF-kappaB (NF-κB) and ERK1/2 in cultured keratinocytes. …”
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30298
Metformin and Probiotics Interplay in Amelioration of Ethanol-Induced Oxidative Stress and Inflammatory Response in an In Vitro and In Vivo Model of Hepatic Injury
Published 2021-01-01“…Therefore, we investigated the effectiveness of combination therapy using a mixture of eight strains of lactic acid-producing bacteria, commercialized as Visbiome® (V) and Met in preventing the ethanol-induced hepatic injury using in vitro and in vivo models. Human HepG2 cells and male Wistar rats were exposed to ethanol and simultaneously treated with probiotic V or Met alone as well as in combination. …”
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30299
Occurrence and Exposure Assessment of Zearalenone in the Zhejiang Province, China
Published 2024-12-01“…This study aims to examine the hazards of zearalenone (ZEN) to humans and assess the risk of dietary exposure to ZEN, particularly in relation to precocious puberty in children from the Zhejiang Province. …”
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30300
Ecological Stress Modeling to Conserve Mangrove Ecosystem Along the Jazan Coast of Saudi Arabia
Published 2025-01-01“…In contrast, island coastal areas exhibit low stress levels due to minimal human activity, except in dense canopy regions where significant stress, likely linked to climate change, was observed. …”
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