Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) by Jonathan Brett, Paul S Haber, Nicholas Lintzeris, Didier Jutras-Aswad, Nadine Ezard, Brendan Clifford, Krista J Siefried, Adrian John Dunlop, Liam Acheson, Carl Moller, Michael Christmass, Kirsten Morley, Steven Shoptaw, Madhukar H Trivedi

“…Qualitative interviews will assess the acceptability of the intervention and outcome measures.Ethics and dissemination This study received ethics approval from the St Vincent’s Hospital Human Research Ethics Committee (2023/ETH00549). …”
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Novel Node Centrality-Based Efficient Empirical Robustness Assessment for Directed Network by Xiaolong Deng, Hao Ding, Yong Chen, Cai Chen, Tiejun Lv

“…Then, with the abundant experiments on the synthetic signed network and real-life networks derived from directed online social media and directed human mobile phone calling network, it has been proved that our ITG and IMpv based on directed social network robustness and node vulnerability assessment method is more accurate, efficient, and faster than several traditional centrality methods such as degree and betweenness. …”
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Thymosin alpha 1 in the prevention of infected pancreatic necrosis following acute necrotising pancreatitis (TRACE trial): protocol of a multicentre, randomised, double-blind, plac... by Tao Chen, Jing Zhou, Jianfeng Tu, Weiqin Li, XinTing Pan, Wenjian Mao, Lu Ke, Wenhua He, Miao Chen, Chengjian He, Weili Gu, Jingyi Wu, Jingchun Song, Haibin Ni, Junli Sun, Guoxiu Zhang, Weiwei Chen, Bing Xue, Xiangyang Zhao, Min Shao, Yuxiu Liu, Zhihui Tong

“…Most of the secondary endpoints will be registered within the index admission including in-hospital mortality, the incidence of new-onset organ failure and new-onset persistent organ failure (respiration, cardiovascular and renal), receipt of new organ support therapy, requirement for drainage or necrosectomy, bleeding requiring intervention, human leucocyte antigens-DR(HLA-DR) on day 0, day 7, day 14, and so on and adverse events. …”
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Association between population viral load surrogate indicator and HIV transmission potential: a prospective cohort study in Xinjiang, China by Qian He, Yongkang Ni, Yuefei Li, Xiaoyuan Hu, Xiaomin Hu, Zhen Ni, Changyu Zeng, Aizimaiti Aikebaier, Bixin Xu, Mingjian Ni

“…Abstract Background New indicators of potential human immunodeficiency virus (HIV) transmission are being actively explored. …”
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Complementary cognitive roles for D2-MSNs and D1-MSNs during interval timing by Robert A Bruce, Matthew Weber, Alexandra Bova, Rachael Volkman, Casey Jacobs, Kartik Sivakumar, Hannah Stutt, Youngcho Kim, Rodica Curtu, Kumar Narayanan

“…These data provide novel insight into basal ganglia cognitive operations beyond movement and have implications for human striatal diseases and therapies targeting striatal pathways.…”
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Electrochemical properties of hydroxyapatite immobilization material for potential cytosensor fabrication by Dennis Adusei, Bernard O. Asimeng, Francis D. Krampa, Elvis K. Tiburu

“…The SHAp/PEDOT: PSS blend was used to modify a screen-printed carbon electrode (SPCE) by drop-casting, followed by seeding of pheochromocytoma (PC 12) and human embryonic kidney (HEK)-293T cells on the modified SPCE to record the EP using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). …”
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Framing behaviour change for sustainable agriculture: Themes, approaches, and future directions by Kingsley Ofosu-Ampong, Wuletawu Abera, Anna Müller, Samuel Adjei-Nsiah, Richard Boateng, Bryan Acheampong

“…Despite the growing demand for behaviour change research and the benefit of understanding how human behaviour influences use cases and the adoption of agricultural innovations, research on how behaviour change occurs and the state of knowledge in the field remains scarce. …”
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Development and experimental validation of a machine learning model for the prediction of new antimalarials by Mukul Kore, Dimple Acharya, Lakshya Sharma, Shruthi Sridhar Vembar, Sandeep Sundriyal

“…Six molecules were purchased, out of which two human kinase inhibitors were identified to have single-digit micromolar antiplasmodial activity. …”
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Preliminary Study on Disinfectant Susceptibility/Resistance Profiles of Bacteria Isolated from Slaughtered Village Free-Range Chickens in Nairobi, Kenya by Igizeneza Acsa, Bebora Lilly Caroline, Nyaga Philip Njeru, Njagi Lucy Wanjiru

“…This will interfere with the cleansing of the respective premises, resulting in contaminated products, which may end-up causing disease in the humans consuming them. Hence, it is recommended that one ascertains the efficacy of respective disinfectant by carrying out disinfectant susceptibility testing to know the effective ones and the appropriate concentration to use.…”
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Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging by Chen Zhu, Youfa Wang, Xiaosong Yang, Qiran Zhao, Wenyan Xu, Xiaolu Wang, Yanjun Liang, Qihui Chen, Shenggen Fan

“…Abstract Background The role of diet in aging is crucial, yet research findings on how specific diets influence human aging remain inconsistent. Understanding the relationship between dietary factors and aging could inform interventions to promote healthier aging outcomes. …”
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Enhancing feature selection for multi-pose facial expression recognition using a hybrid of quantum inspired firefly algorithm and artificial bee colony algorithm by Mu Panliang, Sanjay Madaan, Siddiq Ahmed Babikir Ali, Gowrishankar J., Ali Khatibi, Anas Ratib Alsoud, Vikas Mittal, Lalit Kumar, A. Johnson Santhosh

“…Abstract Facial expression recognition (FER) has advanced applications in various disciplines, including computer vision, Internet of Things, and artificial intelligence, supporting diverse domains such as medical escort services, learning analysis, fatigue detection, and human-computer interaction. The accuracy of these systems is of utmost concern and depends on effective feature selection, which directly impacts their ability to accurately detect facial expressions across various poses. …”
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Interval-Aware Scheduling of Surveillance Drones: Exact and Heuristic Approaches by Kaito Mori, Hiroki Nishikawa, Hiroyuki Tomiyama

“…Drones, with their high mobility and advanced features such as high-resolution cameras, offer a promising alternative to human patrols. Moreover, establishing an optimal patrol schedule for drones is crucial for efficient security operations. …”
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The concept and structural elements of the system of personal empowerment rights of employees by I. M. Kravchenko

“…The article considers the problem of defining the system of personal non-property rights of an employee, as a set of its individual structural basic elements in the system of personal non-property benefits of an individual, and in the general system of human rights. The essence and content of any social, legal phenomena, which are the personal non-property rights of employees, as relevant legal values, can be fully revealed only thanks to the study of objective signs characteristic of these rights. …”
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The Indoor Concentration and Size Distribution of Airborne Bacteria in a Typical Traditional Market by Yi-Tang Chang, Wen-Te Liu, I-Chun Chen, Cheng-Che Chiang, Sai Hung Lau

“…These two sizes of particles are highly likely to deposit in the bronchial tubes of the respiratory tract after being inhaled by humans. Among the AB sampled, isolated and identified were Kocuria marina, K. carniphila, and Staphylococcus sciuri, which were frequently found in a typical indoor TWM. …”
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Identification And Classification of Tattoos In Autopsies; A Retrospective Study by Hatice Kübra Ata Öztürk, Kemalettin Acar, Ayse Kurtuluş Dereli

“…In forensic medicine, tattoos are used for human identification. Tattoos can help determine the origin of death by providing information about individuals' lifestyles. …”
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First Look at the Venoms of Two <i>Sinomicrurus</i> Snakes: Differences in Yield, Proteomic Profiles, and Immunorecognition by Commercial Antivenoms by Xiang-Yu Li, Ya-Qi Zhang, Xin-Ru Qian, Hong-Yan Zhao, Hong-Liang Lu, Jian-Fang Gao

“…Chinese coral snakes (<i>Sinomicrurus</i>) are highly neglected regarding their venom profiles and harm to humans, which impedes our ability to deeply understand their biological properties and explore their medicinal potential. …”
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Umbilical Cord Mesenchymal Stem Cells Overexpressing Heme Oxygenase-1 Promotes Symptoms Recovery in Cystitis Rats by Alleviating Neuroinflammation by Qiongqiong Gao, Zhentao Gao, Minzhi Su, Yong Huang, Chi Zhang, Cuiping Li, Hailun Zhan, Bolong Liu, Xiangfu Zhou

“…In the spinal dorsal horn (SDH), neuroinflammation plays a pivotal role in the development of IC. Injection of human umbilical cord mesenchymal stem cells (hUMSCs) to reduce inflammation is an effective strategy, and heme oxygenase-1 (HO-1) exhibits anti-nociceptive effect in neuroinflammatory pain. …”
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A Comparative Evaluation for Biologic Width following Surgical Crown Lengthening Using Gingivectomy and Ostectomy Procedure by Kiran Kumar Ganji, Veena Ashok Patil, Jiji John

“…However, very little has been done in humans. Aims. The purpose of the study was to evaluate the potential changes in the periodontal tissues, particularly the biologic width, following surgical crown lengthening by two surgical procedures before and after crown placement. …”
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Tumor characteristics and survival rate of axillary metastatic breast cancer patients: a three decades retrospective cohort study by Seyed Mohamad Sadegh Mousavi-kiasary, Mahdis Bayat, Fereshteh Abbasvandi, Batoul Khoundabi, Fatemeh Mousavi, Atieh Akbari, Maryam Bagherian, Afsoon Zandi, Behnam Honarvar, Mohammad Esmaeil Akbari

“…Moreover, estrogen and progesterone receptors, human epidermal growth factor2, tumor pathology type and tumor grade were prognostic factors of axillary LN status. …”
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Cerebrospinal fluid‐specific oligoclonal bands in dogs with idiopathic epilepsy by Junwei Föhr, Julia K. Prümmer, Arianna Maiolini, Eliane Marti, Ilijas Jelcic, Beatriz Vidondo, Mario Ziegler, Andrea Bathen‐Nöthen, Andrea Tipold, Holger A. Volk, Veronika M. Stein

“…Abstract Background In dogs with idiopathic epilepsy (IE), 33% develop resistance to conventional anti‐seizure medication (ASM) despite adequate treatment. In human medicine, an immune‐mediated etiology is suspected in a subset of ASM‐resistant patients with epilepsy and cerebrospinal fluid (CSF)‐specific immunoglobulin G (IgG)‐type oligoclonal bands (OCBs) have been detected. …”
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