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29981
Aberrant methylation of placental development genes in chorionic villi of spontaneous abortions with trisomy 16
Published 2024-04-01“…In humans, aneuploidy is incompatible with the birth of healthy children and mainly leads to the death of embryos in the early stages of development in the first trimester of pregnancy. …”
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29982
The Development and Content of Movement Quality Assessments in Athletic Populations: A Systematic Review and Multilevel Meta-Analysis
Published 2025-01-01“…Abstract Background Despite their prominence in the sport and human movement sciences, to date, there is no systematic insight about the development and content of movement quality assessments in athletic populations. …”
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29983
Clinical and Functional Characteristics of a Novel KLF11 Cys354Phe Variant Involved in Maturity-Onset Diabetes of the Young
Published 2021-01-01“…Background. Mutations in human KLF11 may lead to the development of maturity-onset diabetes of the young 7 (MODY7). …”
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29984
Study on the Application of a Photocatalytic Titanium Dioxide Coating on Glass Beads for the Treatment of Perfluorooctane Sulfonic Acid
Published 2024-01-01“…Perfluorooctanesulfonic (PFOS) acid is a persistent anthropogenic organic fluorinated compound ubiquitous in industrial applications and is resistant to conventional wastewater treatment methods. Human exposure to PFOS can cause adverse health effects. …”
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29985
Exploring the efficacy of drought tolerant, IAA-producing plant growth-promoting rhizobacteria for sustainable agriculture
Published 2025-12-01“…The growing human population and abiotic stresses pose significant threats to food security, with PGPR favorable as biofertilizers for plant growth and stress relief. …”
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29986
Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter
Published 2025-02-01“…N -Acetylneuraminic acid (Neu5Ac) is a negatively charged nine-carbon amino sugar that is often the peripheral sugar in human cell-surface glycoconjugates. Some bacteria scavenge, import, and metabolize Neu5Ac or redeploy it on their cell surfaces for immune evasion. …”
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29987
Differentiating False Loss of Resistance from True Loss of Resistance While Performing the Epidural Block with the CompuFlo® Epidural Instrument
Published 2019-01-01“…A CompuFlo® epidural instrument has been introduced to measure the pressure of human tissues in real time at the orifice of a needle and has been used as a tool to identify the epidural space. …”
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29988
Mf-net: multi-feature fusion network based on two-stream extraction and multi-scale enhancement for face forgery detection
Published 2024-11-01“…Abstract Due to the increasing sophistication of face forgery techniques, the images generated are becoming more and more realistic and difficult for human eyes to distinguish. These face forgery techniques can cause problems such as fraud and social engineering attacks in facial recognition and identity verification areas. …”
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29989
Enhanced quantitative precipitation estimation through the opportunistic use of Ku TV-SAT links via a dual-channel procedure
Published 2025-01-01“…This technique provides rain measurements at a fine temporal resolution (a few tens of seconds) and with a spatial resolution of a few kilometres, which is a good compromise for human activities such as civil security (watershed monitoring, flash flood), agriculture or transport. …”
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29990
Association between gut microbiota and short-chain fatty acids in children with obesity
Published 2025-01-01“…The microbiota influences human metabolism via specific pathways, particularly butyrate, caproate, and the genus Oscillibacter, all closely associated with obesity.…”
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29991
Generation of microdissected DNA probes from metaphase chromosomes when chromosome identification by routine staining is impossible
Published 2020-08-01“…Application of microdissected DNA libraries and DNA probes in numerous and various modern molecular cytogenetic studies showed them as an efficient and reliable tool in the analysis of chromosome reorganization during karyotypic evolution and in the diagnosis of human chromosome pathology. An important advantage of DNA probe generation by metaphase chromosome microdissection followed by sequence-independent polymerase chain reaction in comparison with the method of DNA probe generation using chromosome sorting is the possibility of DNA probe preparation from chromosomes of an individual sample without cell line establishment for the production of a large number of metaphase chromosomes. …”
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29992
Addressing challenges in vector control: a review of current strategies and the imperative for novel tools in India’s combat against vector-borne diseases
Published 2024-07-01“…The promising new vector control tools are insecticide-treated nets with synergist and/or pyrrole chlorfenapyr, alternatives/additions to synthetic pyrethroids like neonicotinoids, clothianidin for indoor residual spray, newer formulations such as Bacillus sphaericus for use in larvicides, attractive toxic sugar baits, especially to curtail outdoor transmission, endectocides like ivermectin for use in animals/humans, insecticidal paints, spatial repellents, insecticide-treated wearables and others. …”
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29993
Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity
Published 2025-01-01“…Additionally, LNP-M effectively delivered DNA-encoded antigens, such as mouse PD-L1 and p53R172H, or monoclonal antibodies targeting mouse PD1 and human p53R282W. This approach inhibited tumor growth or metastasis in several mouse models. …”
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29994
Optimized YOLOV8: An efficient underwater litter detection using deep learning
Published 2025-01-01“…Underwater litter has been a major issue in preserving the marine ecosystem. Human waste is deposited into lakes, rivers, and seas which leads to polluted water. …”
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29995
Enhancers and genome conformation provide complex transcriptional control of a herpesviral gene
Published 2024-11-01“…These data enable us to construct a complete model revealing that the mechanistic diversity of this essential regulatory circuit matches that of human genes.…”
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29996
Biological Impact of Exposure to Extremely Fine-Grained Volcanic Ash
Published 2018-01-01“…Detailed studies about the impact of volcanic ash on human health are still lacking. Therefore, the disease of exposed populations is unknown. …”
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29997
The association between PM2.5 and frailty: evidence from 122 cities in China and 7 countries in Europe
Published 2024-12-01“…PM2.5 particulate matter exposure is a significant factor affecting human health and is crucial in the aging process. …”
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29998
A comparative bio-mechanical performance assessment of additively manufactured bone scaffolds using different beta Ti alloys and Gyroid based cellular structure
Published 2025-03-01“…An exponential rise in demand for artificial implants has emphasized the need for novel biomaterials with good biocompatibility and mechanical properties comparable to human cortical and cancellous bone, to mitigate stress shielding and other post implantation challenges. …”
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29999
An open-label study to determine the maximum tolerated dose of oral ESK-440 administered as a single agent in patients with advanced or metastatic solid tumors
Published 2025-03-01“…Tyrosine kinase inhibitors (TKIs) targeting ALK have improved disease outcomes, but resistance mechanisms are common. This first-in-human trial evaluates ESK-440, a dual inhibitor of ALK and focal adhesion kinase, as a novel strategy for cancers with resistance to ALK-targeting TKIs. …”
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30000
Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation
Published 2019-01-01“…To investigate the protective effect of ginsenoside Rg1 on relieving sepsis-induced lung inflammation and injury in vivo and in vitro. Methods. Cultured human pulmonary epithelial cell line A549 was challenged with LPS to induce cell injury, and CLP mouse model was generated to mimic clinical condition of systemic sepsis. …”
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