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28861
An electrolyte-gated transistor for the monitoring of a CRISPR/Cas activity
Published 2025-05-01“…Detection of Ribonucleic acids (RNA) is a critical step in the identification of viral or bacterial infections in humans and animals. Reverse transcriptase-polymerase chain reaction (RT-PCR) remains the gold standard, but clustered regularly interspaced short palindromic repeats linked to a Cas endoribonuclease particle (CRISPR/Cas) have recently revolutionized the recognition step of two RNAs, i.e. the CRISPR-RNA (crRNA) and the target, providing a much better selectivity compared to the naked hybridization on which RT-PCR is based. …”
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28862
HIV/AIDS prevalence among adolescents in Igbo-Eze South Local Government Area, Enugu State, and the need for faith-based interventions
Published 2024-09-01“…Introduction This study investigated the prevalence of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) among adolescents in Igbo-Eze South Local Government Area (LGA) of Enugu State, Nigeria. …”
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28863
Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity
Published 2018-09-01“…During conducting a first-in-human trial for a new molecular entity, we were able to determine the mechanism of dichotomized variability in plasma drug concentrations, which appeared closely related to adverse drug reactions (ADRs) through integrated omics analysis. …”
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28864
Life Cycle Assessment of Methanol Production from Municipal Solid Waste: Environmental Comparison with Landfilling and Incineration
Published 2025-01-01“…To answer this, this study evaluates the environmental performance of MSW-to-methanol technologies using life cycle assessment (LCA), focusing on key indicators such as global warming potential, resource depletion, and impacts on human health and ecosystem quality. The results reveal that methanol production from MSW significantly reduces global warming potential (GWP) by 87% compared to landfilling and 56% compared to incineration. …”
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28865
Infiltration and subtype analysis of CD3 + CD20 + T cells in lung cancer
Published 2025-01-01“…Abstract Background CD3 + CD20 + T cells (TB cells) are a subset of lymphocytes in the human body that are associated with inflammation. …”
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28866
Factors influencing the adoption of appropriate electronic waste recycling practices in Sub-Saharan Africa: Empirical literature review
Published 2025-01-01“…This provides a path for the implementation of sustainable development goals that aim to protect human health and the environment. Value: This study revealed that the absence of policies, regulations and recycling infrastructure are some of the factors affecting the adoption of e-waste recycling in sub-Saharan Africa. …”
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28867
Machine Learning-Based Integrated Analysis of PANoptosis Patterns in Acute Myeloid Leukemia Reveals a Signature Predicting Survival and Immunotherapy
Published 2024-01-01“…The qRT-PCR results revealed significant differential expression patterns of LGR5 and VSIG4 in normal and human leukemia cell lines (HL-60 and MV-4-11). Conclusions. …”
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28868
Liquid chromatography-high resolution mass spectrometry based analysis of persistent mobile organic compounds in aqueous samples: Method development and optimization
Published 2025-03-01“…Persistent Mobile Organic Compounds (PMOCs) represent a critical threat to water resources due to their high solubility, resistance to degradation, and potential toxicity, posing risks to human health and ecosystems. Their detection and analysis are particularly challenging, necessitating advanced analytical techniques to support regulatory measures and ensure safe drinking water. …”
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28869
Comparative assessment of diagnostic accuracy: Helicobacter pylori stool antigen test versus rapid urease test in adult patients with upper gastrointestinal symptoms
Published 2024-04-01“…Background and aim Helicobacter pylori (H. pylori) is the leading cause of human stomach infections. Accurate diagnosis is ucial for the effective management of H. pylori, leading to the eation of numerous diagnostic techniques, including both invasive and noninvasive methods. …”
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28870
Apply a deep learning hybrid model optimized by an Improved Chimp Optimization Algorithm in PM2.5 prediction
Published 2025-03-01“…PM2.5 pollution in the atmosphere not only contaminates the environment but also seriously affects human health. Therefore, studying how to accurately predict future PM2.5 concentrations holds significant importance and practical value. …”
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28871
A comprehensive analysis of the epidemiological and genomic characteristics of global Serratia Marcescens
Published 2025-01-01“…Results: The study analysed genomes from 33 countries, with major contributions from the USA (27.8%), UK (15.3%), Italy (14.7%), and Japan (10.7%). Human clinical samples accounted for 73.5% of the isolates, primarily from blood (44.8%) and sputum (19.3%). …”
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28872
The impact of the Lesotho health reform in the re-structuring of the village health workers program
Published 2025-01-01“…Abstract Background Community Health Workers locally known as Village Health Workers (VHW) in Lesotho are key members of the primary health workforce, and has been playing a significant role in building primary health systems in many countries and they can fill significant gaps in human resources as low and middle income countries work towards universal health coverage in the era of Sustainable Development Goals (SDGs). …”
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28873
The Role of Artificial Lakes Located in Forests in the Context of Small Retention, Biodiversity and Climatic Changes—Evidence From Southern Poland
Published 2025-01-01“…The model of plant associations showed the occurrence of 24 species of plants within nine plant assemblages in the Phragmitetea and Potametea classes of associations (Biocenotic index 1.007–1.692). Despite human activities, lake condition, as assessed by the ESMI index or the biocenotic diversity indices, is good (0.416–0.648). …”
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28874
DETECTION OF CAMPYLOBACTER SPP. WITH REAL-TIME POLYMERASE CHAIN REACTION
Published 2019-12-01“…Bacteria of Campylobacter genus are ones of the main zoonotic pathogens causing human and animal diseases. Campylobacter organisms are microaerophiles and, therefore, require low oxygen concentration (3–5%) and high carbon dioxide concentration (3–10%) for their growth. …”
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28875
Healthy connections: Crafting compelling healthcare marketing strategies
Published 2024-01-01“…There were 24 keywords with a significant human correlation.…”
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28876
A feasibility study of combining solar/wind energy to power a water pumping system in Jordan's Desert/Al-Mudawwara village
Published 2025-02-01“…In Jordan's isolated desert areas, where underground wells supply water for livestock and human consumption, water pumping systems (WPSs) are essential. …”
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28877
Employee Performance Evaluation Using A New Preferential Voting Process
Published 2020-11-01“…Findings: Interpretation and analysis of structured results obtained using a data envelopment analysis policy based on 360-degree evaluation can be the basis for improving human resources and continuing periodic evaluation to enhance employee performance continuously. …”
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28878
Examining Indonesian College Students’ Behavioral Intention of Using Moodle App for E-Learning Platform
Published 2024-08-01“…However, the technology readiness and acceptance of the human resource to this shift towards distance education via Learning Management System (LMS) remained in question. …”
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28879
Temporal Analysis of Changes in Anthropogenic Emissions and Urban Heat Islands during COVID-19 Restrictions in Gauteng Province, South Africa
Published 2021-05-01“…Therefore, the lockdown restrictions provided an experimental scenario in which pollutants could be drastically reduced, thus accentuated the human impact on microclimates.…”
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28880
An extensive review on implantable antennas for biomedical applications: Health considerations, geometries, fabrication techniques, and challenges
Published 2025-01-01“…Meeting these stringent standards is essential to ensure that IMDs operate safely and effectively within the human body over extended periods. By providing an in-depth review of state-of-the-art solutions and identifying emerging trends, this paper serves as an invaluable resource for researchers, engineers, and medical practitioners involved in the design and deployment of implantable medical devices. …”
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